Wetin na Wilms Tumor? Yu pikin de pan denja? Mek wi no se!

Aw yu go fil if yu de was, drɛs, ɔ jɔs ol yu smɔl pikin ɛn fil smɔl smɔl tin na dɛn bɛlɛ? Dat rili de mek pɔsin fred, nɔto so? Sɔmtɛm lɛk dis, wi nid fɔ tink bɔt dis sik we dɛn kɔl Wilms’ tumor. Lɛ wi tɔk bɔt am jɔs tide.

Wetin rili na Wilms Tumor?

Fɔ tɔk am simpul wan, Wilms tumor na wan kayn kidni kansa we kin apin to yɔŋ pikin dɛn. Na in de mek lɛk 90 pasɛnt pan di pikin dɛn we gɛt kansa na dɛn kidni. sכmtεm, Wilms tכmכro kin apin tכgeda wit כda kכndyushכn dεm we de we dεn bכn am. wi kin kכl dεn tin ya ``kכnεjital sεndrכm'' כ wan kכlekshכn fכ kכndishכn dεm we de de we dεn bכn am.

dis dεn kכl am bak `(Wilms' tumor)` εn `(nephroblastoma)`. Bɔku tɛm, na wan tumbu nɔmɔ kin de na wan kidni. כltu, sכm pikin dεm kin gεt tכmכro na dεn tu kidni dεm `(baylateral),` כ i kin bi mכr dan wan kεnsar εria na wan kidni.

Udat kin gɛt dis pas ɔlman?

Dis na wan sik wae nɔr kin bɔrku wae kin afɛkt big pipul dɛm. Wilms tumor na kansa we kin mɔna pikin dɛn we nɔ rich 15 ia yet, dɛn kin no 95% pan di pikin dɛn we gɛt dis sik bifo dɛn rich 10 ia.

Blak pikin dɛm we kɔmɔt na Afrika kin gɛt di risk smɔl. Pikin dɛn na Eshia kin gɛt smɔl risk. Dɔn bak, gyal pikin dɛn kin gɛt am smɔl pas bɔy pikin dɛn.

Insay smɔl pasɛnt pan di famili dɛn, dɛn dɔn ripɔt bak se dis na sɔntin we kɔmɔt frɔm jin.

Aw dis sik kin kɔmɔn?

Insay kɔntri lɛk Amɛrika, dɛn se na lɛk 500 nyu pipul dɛn kin gɛt Wilms tumor ɛvri ia. I at fɔ fɛn di rayt statystik bɔt aw i de na Sri Lanka, bɔt dis na kansa we dɛn kin si pan pikin dɛn.

Wetin na di congenital syndromes wae yu kin si wit Wilms tumor?

I nɔ kin izi fɔ mek pikin dɛn we gɛt Wilms tumor gɛt ɔda tin dɛn we dɛn bɔn wit. Bɔt i kin apin. Na sɔm pan de men sik dɛn ya:

• Beckwith-Wiedemann syndrome: Pikin dɛm we gɛt dis sindrom gɛt 5% to 10% risk fɔ gɛt Wilms tumor. Dis na wan sik wae de pat na di bɔdi kin gro big pas aw i kin bi. Sɔntɛnde, wan say na di bɔdi kin big pas di ɔda wan.
• WAGR sεndrכm: Pikin dεm we gεt dis sεndrכm gεt 50% risk fכ gεt Wilms tכmכro (di W na di nem tinap fכ Wilms). dis kin mek di ayris (Aniridia) lכs pat pan am, εn i kin mek i gεt prכblεm na di jεnital εn rεnal.
• Denys-Drash sindrom we gɛt di sik:Pikin dεm we gεt dis kכmbayn simptom dεm gεt bכku risk fכ gεt Wilms tכmכro, we kin mek prכblεm bak wit di riprodaktiv כgan dεm εn kidni dεm.

Wetin na di sayn dɛm fɔ Wilms tumor?

Luk fɔ dɛn sayn ya na yu pikin:

• Wan lump ɔ wan tin we strɔng/lump na di bɛlɛ (bɛlɛ). Dis lump ɔ lump kin mek yu fil pen sɔm tɛm, bɔt bɔku tɛm i nɔ kin pen.
• Wan bɛlɛ we de at.
• Blɔd we de na di urine (hematuria).
• Fiva.
• Ay blɔd prɛshɔn (haypa prɛshɔn). Dis kin mek di pikin gɛt blɔd na in nos, in ed at, ɛn in yay dɛn we gɛt blɔd.

If yu gɛt wan ɔ mɔ pan dɛn sayn ya , yu fɔ go to dɔktɔ wantɛm wantɛm.

Wetin kin mek Wilms tumor?

Infakt, wi stil nɔ no di rayt tin we kin mek Wilms in tumbu. Pan ɔl we na smɔl nɔmba pan pipul dɛn kin gɛt jɛnɛtik prɛdispɔzishɔn, i nɔ klia wetin mek i kin divɛlɔp bɔku tɛm.

Aw dɛn kin no (dɛn kin no) Wilms tumor?

If yu notis wan lump na yu pikin in dayaper eria, ɔ if di lump de mek yu yuz big dayapɛt, yu dɔktɔ kin want fɔ tɛst fɔ Wilms tumor. Sɔntɛnde, dɛn tumbu ya kin big pas wan kidni.

If yu pikin gɛt wan pan di sik dɛn we wi bin dɔn tɔk bɔt ɔ gɛt prɔblɛm wit in jɛnɛtiks, yu kin tɔk to yu dɔktɔ ɛn disayd if yu fɔ kɔntinyu fɔ du di tɛst.

Di tɛst dɛn we dɛn kin yuz fɔ no if pɔsin gɛt Wilms tumor na:

• Fɔ chɛk di pikin: We dɛn de du dis, di dɔktɔ kin tek tɛm ol di pikin in bɛlɛ.
• Di tɛst dɛn we dɛn kin du fɔ tek pikchɔ:
• Abdominal ɔltra saund skan.
• CT skan - Bɔku tɛm dɛn kin du dis bay we dɛn injekt spɛshal likwid (kɔntrast).
• Di dɔktɔ kin du ɛkstrem rayt ɔ CT skan bak na in chɛst fɔ si if di kansa dɔn go na di lɔng dɛn.
• Dɛn imej tɛst ya kin ɛp fɔ no if yu pikin gɛt tumbu. Dɛn kin ɛp bak fɔ no difrɛns bitwin Wilms tumor ɛn ɔda kayn kidni kansa.
• Blɔd ɛn urine tɛst: Dɛn tin ya na fɔ tɛst di liva fɔ wok ɛn fɔ tɛst di blɔd we de klɔt.
• Bayopsi: Dis na fɔ tek wan smɔl pat pan di tisu frɔm di tumbu ɛn sɛn am to lab fɔ mek dɛn tɛst am.

Wetin yu nid fɔ no bɔt kansa stej?

Tu we de fɔ no di stej we di Wilms tumor gɛt, dat na aw fa di kansa dɔn skata. dis dεn kכl am ``staging.'' di mכr we di nכmba hכy, na di mכr di kεnsar dεn dכn spre.

Dɔktɔ dɛn na Yuropian kɔntri dɛn de yuz di Intanɛshɔnal Sɔsayti fɔ Pidiatrik Ɔnkɔlɔji (SIOP) sistɛm. Dɔktɔ dɛn na Amɛrika ɛn Kanada de yuz di Children’s Oncology Group (COG) sistem.

di wan difrεns bitwin dεn tu mεtכd ya na dat insay di COG mεtכd, dεn de chεk di stej fכ di tכmכro afta dεn כpεrayshכn εn bifo dεn gi kεmothεrapi (anti-kansa dכg dεm). Insay di SIOP we, dɛn kin du di ɔpreshɔn afta di kemotɛrapi ɛn dɛn kin chɛk di stej afta dat nɔmɔ.

di stej dεm we de כnda di COG sistεm dεn sheb dεm lεk dis:

• Stej I: di tכmכro de כnli insay di pikin in kidni εn dεn kin pul am kכmplit wan wit כpεrayshכn.
• Stej II: di tכmכro dכn gro kכmכt na di kidni, bכt dεn kin pul am kכmplit wan wit כpεrayshכn.
• Stej III: Dɛn nɔ kin ebul fɔ pul di tumbu ɔltogɛda. di kεnsar sεl dεm de stil de na di pikin in bεlε (abdominal cavity).
• Stej IV: Di kansa dɔn pas di pikin in bɛlɛ ɛn in bɛlɛ to ɔda say dɛn lɛk di lɔng, liva, bon, ɛn bren.
• Stej V: di tכmכro de na di tu kidni dεm (baylatarכl). insay dis stej, dכkta dεm de luk di stej fכ di tu kidni dεm sεparat wan.

Aw dɛn kin trit Wilms tumor?

Bɔku tɛm, dɛn kin trit Wilms in tumbu wit ɔpreshɔn ɛn kemotɛrapi. Sɔntɛnde, dɛn kin yuz redyushɔn tɛrapi bak.

Pikin dɛn we gɛt tumbu we nɔ gɛt bɔku prɔblɛm, usay di kansa nɔ bin dɔn skata ɛn dɛn kin pul di tumbu kpatakpata, kin ebul fɔ du ɔpreshɔn dɛn wan. Sɔntɛnde, dɛn kin gi dɛn kemotɛrapi bifo dɛn du di ɔpreshɔn fɔ mek di tumbu smɔl, ɛn dis kin mek di ɔpreshɔn sef.

Bɔku tɛm dɛn kin gi kemotɛrapi insay di bɛlɛ (IV). Dɛn kin du dis na ɔspitul ɔ na ɔspitul.

Yu pikin kin gɛt bad bad tin dɛn we kin apin to am we i de tek kimotɛrapi ɔ redyushɔn tɛrapi. If dis apin, mek shɔ se yu tɛl yu dɔktɔ. Sɔm tin dɛn de we yu kin du fɔ ridyus di sayd ɛfɛkt ɛn mɛrɛsin dɛn we yu kin gi yu pikin.

Yu tink se dɛn go ebul fɔ mek Wilms in tumbu nɔ apin?

Natin nɔr de fɔ rili yu ɔ yu pikin kin du fɔ mek ɔr nɔr gɛt Wilms tumor. Dis na sɔntin we wi nɔ ebul fɔ kɔntrol.

Wetin na di prɔgnosis fɔ pɔsin we gɛt Wilms tumor?

di prכgnosis fכ Wilms in tכmכro kin jεnarali gud in mכst kεys dεm. Bɔku tɛm, di tin we kin apin kin rili fayn, mɔ if di dɔktɔ ebul fɔ pul di tumbu kpatakpata ɛn di kansa nɔ dɔn skata ɔdasay na di bɔdi. כltu, sכm chans de fכ mek Wilms in tכmכro ``rεkכr''.

Wilms tumor kin kil pɔsin?

Pan ɔl we dɛn kin trit Wilms tumor fayn fayn wan wit wan kɔmbayn ɔpreshɔn, kemotɛrapi, ɛn/ɔ redyushɔn tɛrapi, .Dis stil na kansa. So, i kin kil pɔsin. Na dat mek i impɔtant fɔ no am kwik ɛn bigin fɔ trit am.

Wetin na di sɔvayv rit fɔ Wilms tumor?

Na lɛk 90% pan di pipul dɛm we dɛn no se gɛt Wilms tumor stil de alayv afta fayv ia. dis rεt kin difrεn sכmtεm dipכnt pan tin dεm lεk di stej we di kεnsar de, di sayz fכ di tכmכro, εn aw di kansa sεl dεm de luk כnda maykroskכp (histology). Pan ɔl we dɛn bin de tɔk se pikin dɛn we nɔ rich 2 ia yet kin gɛt smɔl risk fɔ gɛt di sik bak, naw di ej nɔ impɔtant pas aw i bin de bifo.

Ustɛm a fɔ si mi dɔktɔ bɔt Wilms tumor?

If dɛn de trit yu pikin fɔ Wilms in tumor, go to yu dɔktɔ if yu gɛt ɛnitin fɔ wɔri bɔt ɔ kwɛstyɔn. Ɛspɛshali if yu notis ɛni nyu sayn ɔ if i tan lɛk se sɔntin de wɔs, mek dɛn no wantɛm wantɛm.

We yu de du yu tritmɛnt, yu mɛdikal tim go tɛl yu wetin fɔ wach fɔ, lɛk sayn dɛm fɔ urinary tract infection. If dis apin, yu go nid fɔ go na di imejensi rum.

Di pikin go nid bak fɔ go fɔ fala di visit ɔltɛm fɔ mek shɔ se dɛn de du wɛl. Di dɔktɔ kin rifer di pikin bak to spɛshal dɔktɔ we de mɛn di kidni (nɛfrɔlɔjis) ɔ spɛshal pɔsin we sabi bɔt di urinary system (urologist).

Aw a go ɛp mi pikin fɔ gɛt wɛlbɔdi afta dɛn dɔn trit mi wit Wilms tumor?

I impɔtant fɔ mek yu pikin du dɛn tin ya:

• Drink inof wata fɔ ɛp yu kidni fɔ wok fayn fayn wan.
• Nɔ yuz mɛrɛsin dɛn lɛk aspirin, ibuprofen, ɛn naproxen. Tɔk to yu pikin in dɔktɔ bɔt us prɔdak nɔ go ambɔg yu pikin in kidni.
• Chek yu blɔd prɛshɔn ɔltɛm.

Yu tink se Wilms tumor de mek pɔsin fil pen?

Sɔntɛnde Wilms tumor kin mek yu fil pen, bɔt nɔto ɔltɛm i kin mek yu fil pen.

Wetin na di difrɛns bitwin Wilms in tumor (nephroblastoma) ɛn nyuroblastoma?

Pan ɔl we dɛn tu wɔd ya kin tan lɛk se dɛn fiba, dɛn na tu kayn kansa we kin bigin na tu difrɛn kayn sɛl dɛn. Nephroblastoma na kansa na di kidni dɛm. Nyuroblastoma na kansa we kin bigin na di nerve cells. Bɔku tɛm i kin bigin na di adrenal gland dɛm, bɔt i kin kam insay di kidni dɛm bak. Dɛn tu kayn kansa ya kin apin to pikin dɛn, ɛn dɛn ɔl tu kin kam lɛk wan lump na di bɛlɛ. So, i impɔtant fɔ gɛt kɔrɛkt diagnosis.

If dɛn no se yu pikin gɛt Wilms tumor, yu dɔktɔ go mɔs tɛl yu fɔ go to wan mɛdikal sɛnta we spɛshal fɔ trit kansa we pikin dɛn gɛt. Pan ɔl we Wilms tumor nɔ kin bɔku, na sik we pɔsin kin mɛn. Yu pikin kin fit bak fɔ tek pat pan klinik trial. Bɔku pikin dɛn we gɛt Wilms tumor kin rayt dɛn nem na dis program. Bɔku tin dɛn we dɔn apin pan Wilms tumor tritmɛnt na di rizɔlt fɔ dɛn klinik trial ya.

Di tin we impɔtant pas ɔl (Take-Home Message) .

Okay, so wi don tok plenti boht Wilms in tumor, no so? Di men tin we yu fɔ mɛmba na dat , if yu si ɛnitin we nɔ kɔmɔn ɔ swɛlin na yu pikin in bɛlɛ, nɔ panik ɛn go to dɔktɔ wantɛm wantɛm.

• Wilms in tumor na kansa we kin kam na di kidni dɛm fɔ yɔŋ pikin dɛm.
• Pan ɔl we wi nɔ no di rayt tin we mek dis kin apin, sɔm tin dɛn kin apin we pɔsin gɛt frɔm in jɛnɛtiks.
• If dɛn no di sik kwik kwik wan ɛn trit am fayn, di chans fɔ mek i wɛl go bɔku.
• Ɔpreshɔn, kemotɛrapi, ɛn sɔntɛnde redyushɔn tɛrapi na di men tritmɛnt dɛn.
• Ivin afta yu dɔn gɛt tritmɛnt, i rili impɔtant fɔ fala di dɔktɔ in instrɔkshɔn dɛn gud gud wan ɛn go fɔ chɛk-ap di tɛm we dɛn dɔn sɛtul.

Nɔ fred. Mɛdikal sayɛns dɔn rili go bifo tide. Di tin we impɔtant pas ɔl na we yu pe atɛnshɔn ɛn du sɔntin kwik kwik wan. A de wish yu pikin fɔ wɛl kwik kwik wan!

` Wilms tumor, nephroblastoma, pikin kansa, kidni kansa, pikin dɛn wɛlbɔdi, kansa simptom, kansa tritmɛnt