Yu ɔ pɔsin we yu sabi gɛt aTTP (acquired thrombotic thrombocytopenic purpura), we na wan sik we nɔ kin apin so ɔltɛm ɛn we kin rili siriɔs? If na so, yu go dɔn yɛri bɔt wan mɛrɛsin we dɛn kɔl Caplacizumab. Bikɔs na spɛshal drɔg we gɛt sɔm kɔmplikɛt nem, lɛ wi tɔk bɔt am simpul wan, di we we yu go ɔndastand, ɛn di we we go mek yu gɛt padi biznɛs, nɔto so?
Us kayn mɛrɛsin na Caplacizumab?
Fɔ tɔk am simpul wan, aTTP na siriɔs prɔblɛm wit wi blɔd we de klɔt ɛn we de blɔd. Wetin kin apin na dat, smɔl smɔl blɔd dɛn kin kam na di blɔd vesel dɛn ɔlsay na di bɔdi, ɛn wi pletlɛt dɛn kin go dɔŋ kwik kwik wan. Plɛtlɛt na wan kayn sɛl we de ɛp fɔ stɔp blɔd. We dɛn yuz dɛn fɔ mek blɔd klot we nɔ nid dis we, dɛn nɔ kin du fɔ stɔp blɔd usay i rili nid.
Dis na di say we wan drɔg we dɛn kɔl Caplacizumab kin kam fɔ ɛp wi. I de wok bay we i de stɔp dɛn blɔd klɔt dɛn de fɔ mek dɛn nɔ stik togɛda ɛn mek blɔd klɔt dɛn we nɔ nid. na wan kayn spεsifi k protin (monoclonal antibodi) . Dis min se dɛn mek am fɔ du sɔntin nɔmɔ pan wan patikyula tin we dɛn want fɔ du.
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu tek dis mɛrɛsin
Bifo yu bigin fɔ tek dis mɛrɛsin, i rili impɔtant fɔ mek yu gi yu dɔktɔ wan kɔmplit akɔdin to yu wɛlbɔdi. Nɔ ayd ɛnitin. Mek shɔ se yu tɛl dɛn, mɔ:
- If yu gɛt prɔblɛm wit blɔd.
- If yu gɛt fɔ du ɛni ɔpreshɔn jisnɔ.
- If yu gɛt liva sik.
- If yu gɛt ɛni alɛji to Caplacizumab, ɔda mɛrɛsin, it, ɔ day.
- If yu gɛt bɛlɛ, yu de tray fɔ gɛt bɛlɛ, ɔ yu de gi pikin in bɛlɛ.
I impɔtant fɔ mek yu sef fɔ tɔk bɔt ɔl dis wit yu dɔktɔ ɛn nɔ ayd ɛnitin.
Aw fɔ yuz di mɛrɛsin?
Dis na mɛrɛsin we dɛn kin gi as injɛkshɔn. Dɛn kin injekt am na vein ɔ ɔnda di skin. Dɛn kin gi am na ɔspitul ɔ klinik. Bɔt sɔntɛnde yu kin nid fɔ yuz dis injɛkshɔn na os.
If na so i bi, di dɔktɔ ɔ di wan dɛn we de wok na di nɔs go gi yu di ful trenin we yu nid. So nɔ fred. Dɛn go ɛksplen ɔltin klia wan, ivin aw fɔ pripia di mɛrɛsin ɛn aw fɔ injɛkt am. Yuz di rayt doz, di rayt tɛm, lɛk aw di dɔktɔ tɛl yu.
I rili impɔtant:Nɔ ɛva trowe nidul ɛn sirinj dɛn we yu dɔn yuz na di dɔti. Bifo dat, put dɛn insay spɛshal kɔntena we gɛt shap tin dɛn. If yu nɔ gɛt wan, aks yu dɔktɔ fɔ gɛt wan.
Wetin a go du if a mis wan doz fɔ mɛrɛsin?
If yu mis wan doz, tek am jɔs afta yu mɛmba. Bɔt if i let pas 12 awa, skip di doz we yu mis ɛn tek yu nɛks doz di tɛm we yu de tek am ɔltɛm. Nɔ tek tu dos wan tɛm.
Wetin fɔ du if yu tek bɔku mɛrɛsin?
If yu tink se yu dɔn tek bɔku mɛrɛsin, go na ɔspitul in Imejɛnsi Yunit (ETU) wantɛm wantɛm. Ɔ kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital .
Tin dɛn we yu fɔ tek tɛm wit we yu de tek mɛrɛsin
Yu nid fɔ tink smɔl mɔ bɔt yu sef we yu de tek dis mɛrɛsin.
- Risk fɔ blɔd: Bikɔs di men wok we dis mɛrɛsin de du na fɔ stɔp blɔd fɔ klɔt, di risk fɔ mek blɔd kɔmɔt smɔl. Dis min se ivin smɔl wund kin blɔd pas aw i kin kɔmɔt. Yu kin ivin gɛt brus na yu bɔdi. So, tek tɛm wit tin dɛn we go mek pɔsin wund, lɛk fɔ yuz tin dɛn we shap.
- Ɔpreshɔn ɛn tritmɛnt fɔ yu tit: If yu go gɛt ɛni ɔpreshɔn ɔ ɔda mɛrɛsin, mek shɔ se yu tɛl di dɔktɔ se yu de tek dis mɛrɛsin. Yu fɔ tɛl yu dɛntist bak bifo yu du ɛni ɔpreshɔn pan yu tit.
- Ɔda mɛrɛsin dɛn: Tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek, nɔto jɔs di wan dɛn we dɔktɔ gi yu, bɔt tɛl yu bak di mɛrɛsin dɛn we yu nɔ de bay, vaytamɛn dɛn, ɛbul mɛrɛsin dɛn, ɛn sɔpɔtmɛnt dɛn. Blɔd tin dɛm (e.g., warfarin, enoxaparin, apixaban, rivaroxaban) kin intarakt wit dis mɛrɛsin.
- Di mɛdikal chɛk-ap: Go na di klinik dɛn di de dɛn we dɛn dɔn sɛtul as di dɔktɔ tɛl yu ɛn chɛk yu kɔndishɔn.
Wetin na di bad tin dɛn we kin apin to pɔsin?
Lɛk ɛni mɛrɛsin, Caplacizumab kin mek sɔm sayd ɛfɛkt. Sɔm pan dɛn tin ya siriɔs, ɛn ɔda wan dɛn kin kɔmɔn. De impɔtant tin na fɔ no bɔt dɛn sik ya ɛn tek akshɔn kwik if nid de.
| Tayp fɔ di sayd ɛfɛkt | Di sayn dɛm wae yu kin gɛt |
|---|---|
| Notis yu dɔktɔ wantɛm wantɛm! | |
| Alɛji we pɔsin kin gɛt | Skin rash, it, swel na di fes, lip, tong ɔ trot, i nɔ izi fɔ blo. |
| Sayn dɛn we de sho se pɔsin de blɔd bad bad wan | Blak ɔ tar stɔl, vɔmit blɔd we tan lɛk kɔfi grɔn, rɛd ɔ dak brawn urine, brus ɔ rɛd/pɔpul spat na di skin, ɛn blɔd we nɔ de stɔp na yu nos ɔ gam. |
| If dɛn tin ya kɔntinyu ɔ de mɔna yu, tɛl yu dɔktɔ. | |
| Ɔda sayd ɛfɛkt dɛn | Ed pen, mɔsul pen, bak pen, taya. |
Aw a fɔ kip di mɛrɛsin?
Fɔ mek di mɛrɛsin kɔntinyu fɔ gɛt di kwaliti, i impɔtant fɔ kip am di rayt we.
- Kip fa frɔm smɔl pikin dɛn ɛn animal dɛn we yu kin mɛn na os.
- Yu kin kip am na frij ɔ na rum tɛmpracha (dɔwn 30°C). Nɔ ɛva put am na friza.
- Kip di mɛrɛsin na di ɔrijinal bɔks we i kam insay, fa frɔm layt.
- If yu kip am na rum tɛmpracha, yu kin kip am fɔ 2 mɔnt. Bɔt nɔ put ɛni mɛrɛsin we dɛn dɔn kip da we de bak na frij. If ɛni wan we lɛf afta 2 mɔnt, trowe am.
- Nɔ yuz mɛrɛsin we dɔn pas.
Mɛsej we dɛn kin kɛr go na os
- Caplacizumab na wan patikyula vaysin we dɛn kin gi fɔ wan siriɔs blɔd dizayd we dɛn kɔl aTTP.
- Tek tɛm bad bad wan pan injury, bikɔs i kin gɛt bɔku risk fɔ mek yu blɔd we yu de tek dis mɛrɛsin.
- Mek shɔ se yu tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn we yu de tek.
- If yu notis sayn dɛm fɔ siriɔs blɔd (blak stɔl, vɔmit blɔd) ɔ sayn dɛm fɔ alɛji (we yu fes de swel), go to dɔktɔ wantɛm wantɛm.
- Dis mɛrɛsin na fɔ yu nɔmɔ. Nɔ ɛva sheb am wit ɔda pipul dɛn.
- Ɔltɛm fala yu dɔktɔ in instrɔkshɔn dɛn di rayt we.
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