Yu gɛt dɛn strenj sayn ya? Lɛ wi tɔk bɔt Carcinoid Syndrome!

Sɔntɛnde, wi nɔ kin no di rayt tin we de apin na wi bɔdi, nɔto so? Yu dɔn ɛva gɛt blɔd wantɛm wantɛm, i nɔ kin izi fɔ blo, yu bɛlɛ kin pen, ɛn yu kin gɛt dayarɛa? Dis nɔto jɔs random tin dɛn. Sɔntɛnde, dɛn tin ya kin bi sayn fɔ wan sik we nɔ kin apin so ɔltɛm we dɛn kɔl Carcinoid Syndrome. Lɛ wi tɔk mɔ bɔt dis tide .

Wetin na di sik we dɛn kɔl Carcinoid Syndrome?

Fɔ tɔk am simpul wan, carcinoid syndrome na wan kɔlekɛshɔn fɔ simptom dɛm we kin kam wit wan kayn kansa we de gro na yu bɔdi we dɛn kɔl neuroendocrine tumors (NETs) . dis nyuroεndokrin sεl dεm na spεshal tכp sεl dεm we de involv insay wi nεv εn כmon sistεm dεm. NET dεm de apin we dεn sεl dεm ya de divayd wan wan εn mכltiplכ kwik kwik wan, we de fכm tכmכro dεm.

Naw yu go de wɔnda if dis na sik we de ambɔg ɔlman. Nɔ, fɔ tru, na wan sik we nɔ kin apin so ɔltɛm . Stɔdi dɔn sho se lɛk wan pan ɛvri fayv pipul dɛn we gɛt nyuroɛndokrin tɔŋ (NET) kin gɛt kansa sik. NET nɔto so kɔmɔn sɛf, wit dɛn se na 5 pan 100,000 pipul dɛn na Amɛrika.

dis NET dεm, spεshal wan dεm we de na yu gεstrointestinal trakt כ lכng dεm, de rilis bכku כmon dεm lεk sεrotonin εn כda kεmikכl dεm na di bכdi wan tεm. Na da tɛm de di sayn dɛm fɔ carcinoid syndrome de sho. Sɔmtɛm, yu kin no fɔs se yu gɛt NET afta di sayn dɛm fɔ dis sik dɔn apia.

Na smɔl tɛm nɔmɔ, if dɛn nɔ no ɛn trit dis kansa sik fayn fayn wan, i kin mek pɔsin gɛt wan imejensi we go mek pɔsin in layf de pan denja we dɛn kɔl ‘carcinoid crisis.’ So, i rili impɔtant fɔ mek wi no bɔt dis.

Wetin na di sayn dɛm fɔ Carcinoid Syndrome?

Lɛ wi tek wan luk pan de sayn dɛm wae kin kam wit dis sik. Si if yu gɛt ɛni wan pan dɛn sayn ya, wan bay wan:

• Flushing: Dis kin mek yu nɔ fil fayn smɔl. I tan lɛk se yu de blush we yu shem, bɔt if i kin apin bɔku tɛm fɔ natin, yu fɔ wɔri.
• Wiz ɛn shɔt briz (dyspnea): I kin fil lɛk se i at fɔ blo, ɔ lɛk sawnd we de wisɛl we de kɔmɔt na di chɛst.
• Bɛlɛ kramp ɛn bɔm, dayarɛa ɔltɛm: Na bɛlɛ de at wit kɔntinyu, siriɔs dayarɛa. Sɔntɛnde, i nɔ kin izi fɔ kɔntrol am.
• Fat poops we de smɛl bad: Di poop kin tan lɛk ɔyl ɛn gɛt wan ɔda smel.
• Ɛdima ɔ swel na yu fut ɛn yu leg dɛn:Sɔntɛnde dis kin bi sayn fɔ mek yu at pwɛl, so i impɔtant fɔ go to dɔktɔ kwik kwik wan.
• Di kayn we aw man dɛn kin want fɔ du mami ɛn dadi biznɛs ɔ we nɔ kin ebul fɔ tinap tranga wan: Sɔm pipul dɛn kin gɛt dɛn kayn tin ya.
• di skin de yכlכ εn di wayt dεm na di yay (Jaundice): Dis na wetin wi kin kכl ‘jaundice’. I kin bi prɔblɛm wit di liva.
• Diziz ɔ fil lɛk se yu nɔ gɛt bɛtɛ trɛnk: Dis kin bi sayn fɔ se yu blɔd prɛshɔn dɔn go dɔŋ.
• Fɔ fil lɛk se yu at de rɔn: Yu kin jɔs fil lɛk se yu chɛst de bit fast fast.

If yu kɔntinyu fɔ gɛt wan ɔ mɔ pan dɛn sik ya, mek shɔ se yu go to dɔktɔ fɔ tɔk bɔt dɛn. Dɛn tin ya kin bi sayn dɛm bak fɔ ɔda sik dɛm, bɔt i impɔtant fɔ kɔnfirm se yu gɛt kansa sik.

Wetin mek dis kayn kansa sik kin apin?

As a bin dɔn tɔk bifo tɛm, kansa sik kin apin if yu gɛt nyuroɛndokrin tɔŋ (NET). dis NET dεm na tכmכro dεm we de divεlכp frכm spεshal sεl dεm na yu nyuroεndokrin sistεm. Dɛn sɛl ya de mek ɔmon dɛn ɛn pul ɔmon dɛn na di bɔdi.

כltu, dεn NET dεm ya kin divεlכp na ples dεm lεk yu gεstrointestinal trakt, lכng, εn pankrias. כltu, di kansa sεndr כm kin kכz f כ di NET dεm na di gεstrointestinal trakt כ di lכng dεm we de rilis bכku כmon dεm (especially sεrotonin) wan wan insay di bכdi.

Tink bɔt am lɛk pɔt we de tɔn di wata smɔl smɔl, dɛn sɛl ya nɔmal fɔ pul ɔmon dɛn smɔl smɔl. Bɔt we NET fɔm, i tan lɛk se dɛn dɔn tɔn di pɔt wantɛm wantɛm, ɛn bɔku ɔmon dɛn kin kɔmɔt wan tɛm. Na da tɛm de de sayn dɛm fɔ dis sik kin apia.

Udat dɛn kin gɛt bɔku risk fɔ gɛt kansa sik?

Di men tin we kin mek dis apin na we yu gɛt nyuroɛndokrin tɔŋ (NET) na yu bɛlɛ ɔ yu lɔng . In ɔda wɔd, di carcinoid syndrome nɔ kin apin if yu nɔ gɛt NET.

Dat min se, if dɛn dɔn no se yu gɛt NET, yu fɔ wɔri bak bɔt dis sik. Sɔntɛnde, if sɔmbɔdi na di famili dɔn gɛt NET, dat kin bi risk factor bak to sɔm mak, bɔt i kin rili rare.

Wetin na di prɔblɛm dɛn we kin apin we pɔsin gɛt Carcinoid Syndrome?

Carcinoid syndrome nɔto jɔs wan sɛt ɔf simptom dɛm, i kin mek yu gɛt bɔku siriɔs prɔblɛm dɛm. Wan pan dɛn kayn tin ya na di sik we kin mek pɔsin in layf de pan denja we dɛn kɔl ‘carcinoid crisis’ we a bin dɔn tɔk bɔt.

Lɛ wi luk sɔm ɔda prɔblɛm dɛn we kin apin:

• Karsinoid at sik: .Dis nɔ kin apin bak, bɔt i kin mek pɔsin in layf de pan denja. di כmon dεm we di NET dεm de kכmכt de afekt di layn dεm na yu at chεmba dεm, valv dεm, εn blɔd vεsul dεm. Dis kin ivin mek yu at pwɛl.
• Mesenteric fibrosis: NET kin mek inflameshn εn skata na di mesentery, di tisu we de kכnekt yu intestines to yu bכdi wכl. Dis kin ambɔg di we aw di bɔdi de wok.
• Pwɛl hat: Carcinoid syndrome kin afɛkt yu bɔdi in ebul fɔ yuz wan impɔtant amino asid we dɛn kɔl triptofan. Triptofan de ɛp fɔ mek sɛrotonin. Serotonin na wan kemikal we de na di bren we de kɔntrol tin dɛn lɛk aw wi de fil, aw wi de biev, ɛn aw wi de slip. So if yu nɔ gɛt bɛtɛ sɛrotonin, dat kin mek yu gɛt pwɛl hat.

Di denja kɔndishɔn wae dɛn kɔl carcinoid crisis

Carcinoid crisis na wan imejensi wae kin rili rare bɔt kin mek pɔrsin in layf de pan denja . I kin apin bikɔs ɔf ɔpreshɔn, ɔda mɛrɛsin dɛn, ɔ injury bikɔs ɔf aksidɛnt.

Di kwaliti dɛm fɔ dis na:

• Big chenj dɛn na di blɔd prɛshɔn: Blɔd prɛshɔn kin go dɔŋ tumɔs (haypotension) ɔ go ɔp tumɔs wantɛm wantɛm.
• Fɔ flash bad bad wan: Di wan ol bɔdi kin tɔn rɛd wantɛm wantɛm ɛn i kin fil wam.
• I nɔ kin izi fɔ yu fɔ blo (Dyspnea): I kin apin we yu nɔ kin blo bɛtɛ.
• Kɔnfyushɔn: Yu kin fil lɛk se dɛn de ambɔg yu kɔnshɛns.

I rili impɔtant fɔ mek pɔsin we gɛt kansa ɔr nyuroɛndokrin tɔŋ (NET) kɛr kad we de sho aw dɛn de. Dis kin rili ɛp dɛn if dɛn nid fɔ go to dɔktɔ kwik kwik wan. Dɔn bak, if dɛn go du ɔpreshɔn pan yu, i impɔtant fɔ tɛl yu dɔktɔ dɛn bɔt dis sik. Dɔn dɛn kin gi yu mɛrɛsin bifo ɛn di tɛm we dɛn de du di ɔpreshɔn fɔ ridyus di risk fɔ gɛt ‘carcinoid crisis’.

Aw dɛn kin no se pɔsin gɛt Carcinoid Syndrome?

Dɔktɔ dɛn kin yuz bɔku tɛst fɔ no if pɔsin gɛt dis sik. Lɛ wi tek wan luk pan wetin dɛn bi:

• Yurin tɛst: Dis de chɛk di lɛvɛl dɛn fɔ sɔm ɔmon dɛn na yu urine, spɛshal wan bayprodukt fɔ sɛrotonin we dɛn kɔl 5-HIAA (5-hydroxyindoleacetic acid) .
• Fyzikal ɛgzam ɛn mɛdikal istri: De sayn dɛm fɔ carcinoid syndrome kin tan lɛk ɔda sik dɛm wae nɔr kin siriɔs, so yu dɔktɔ go aks yu ditayli bɔt yu sayn dɛm, aw lɔng dɛn dɔn de, ɛn if dɛn de wɔs.
• Blɔd tɛst dɛn:Dɛn tin ya de chɛk di lɛvɛl dɛn we di tin dɛn we de kɔmɔt na yu ɔgan ɛn tisu dɛn de kɔmɔt na di blɔd. If di lɛvɛl fɔ sɔm tin dɛn go ɔp ɔ dɔŋ wantɛm wantɛm, dat kin bi sayn fɔ sik. Fɔ ɛgzampul, dɛn kin luk wan mak we dɛn kɔl Chromogranin A.
• Nyuroεndokrin Positron Emission Tomography (PET) skan: dis na spεshal skan we de yuz wan day we dεn kכl gallium 68 dotatate fכ fכn di say we di nyuroεndokrin tכmכro dεm (NET) de.
• CT skan: CT skan de yuz X-ray ɛn kɔmpyuta fɔ mek tri-dimɛnshɔnal (3D) pikchɔ dɛn fɔ yu ɔgan ɛn bon dɛn. Dis kin ɛp bak fɔ no usay ɛni lumps de ɛn di sayz.
• Ultrasound scan: Dis de yuz sawnd wev fɔ mek pikchɔ dɛn fɔ di ɔgan dɛn.
• MRI skan (Magnetic Resonance Imaging (MRI): Dis kin yuz big magnet, redio wev, ɛn kɔmpyuta fɔ mek ditayli pikchɔ dɛn bɔt di insay pat pan di bɔdi.
• Ɛndoskopi: Insay dis tɛst, dɔktɔ kin put wan lɔng, tin tiub wit kamɛra ɛn layt insay yu bɔdi fɔ chɛk am. Fɔ ɛgzampul, dɛn kin yuz dis we fɔ chɛk di bɛlɛ ɔ di insay.

Wetin na di tritmɛnt fɔ Carcinoid Syndrome?

di kansa sεndrכm na di nyuroεndokrin tכmכro dεm (NET) de kכz am. So, we dɛn trit dɛn tumbu dɛn de, dɛn kin trit di sik bak.

Bɔku men we dɛn de fɔ trit pɔsin:

• Ɔpreshɔn: Dɛn kin pul di nyuroɛndokrin tɔŋ dɛn ɔl ɔ ridyus dɛn saiz. Di kayn ɔpreshɔn de dipen pan di say ɛn di sayz we di tumbu de.
• Somatostatin analogs: Dis na spɛshal kayn mɛrɛsin. Dɛn mɛrɛsin ya kin mek yu bɔdi nɔ mek bɔku ɔmon. dεn kin εp bak fכ kכntrכl di tכmכro dεm we de gro we di kεnsar sεl dεm dכn spre to כda pat dεm na di bכdi (mεtastas). Sɔm ɛgzampul dɛn na di mɛrɛsin dɛn we dɛn kɔl Ɔktriɔtayd ɛn Lanrɛɔtayd .
• Targeted therapy: Dis na spɛshal tritmɛnt we dɛn kin yuz bak fɔ kil di kansa sɛl dɛm. insay dis, dεn kin gi dכg dεm fכ tכk to spεsifi k jin dεm כ protin dεm na di kεnsar sεl dεm.
• Kimotɛrapi: Dis kin yuz drɔgs fɔ kil di kansa sɛl dɛn. Kimotɛrapi nɔ de wok di sem fɔ ɔl kayn NET.
• Embolization: Insay dis we ya, di bכdi we de gi bכdi to di tכmכro de blok, we de pwεl di tכmכro. Dis na tritmɛnt we dɛn kin yuz mɔ fɔ NET dɛn na di liva.

Yu tink se dɛn kin ebul fɔ avɔyd Carcinoid Syndrome?

Rili,Nɔ we nɔ de fɔ mek dɛn nɔ gɛt kansa bikɔs i gɛt fɔ du wit nyuro ɛndɔkrin tɔŋ (NET). Bikɔs no we nɔ de we dɛn no fɔ mek dɛn nɔ gɛt NET, no we nɔ de fɔ mek dɛn nɔ gɛt di sik dɛn we kin kɔmɔt frɔm dɛn.

Bɔt if yu no se yu gɛt NET, fɔ no di sayn dɛm fɔ kansa sik kwik kwik wan ɛn bigin tritmɛnt kin ridyus di risk fɔ gɛt prɔblɛm.

Aw a kin kia fɔ misɛf? / Aw a kin manej di simptom dɛm?

If yu gɛt kansa sik, yu kin gɛt nyuroɛndokrin tɔŋ (NET) bak. So, if yu gɛt sayn dɛm fɔ carcinoid syndrome, tɛl yu dɔktɔ wantɛm wantɛm. Dɛn kin ebul fɔ evaluate yu kɔndishɔn ɛn rεkomεnd di tεst dεm wae yu nid fɔ si if yu gɛt NET.

Di tri men sayn dɛm wae de sho se yu gɛt kansa na wae yu de flash, yu de swɛt, ɛn yu de gɛt dayarɛa. Na sɔm tin dɛn ya yu kin du fɔ ɛp fɔ manej dɛn tin ya:

• Flush: Dis na di we aw yu nervɔs sistɛm de ansa we yu gɛt strɛs na yu bɔdi ɔ yu maynd. Fɔ ridyus dis, tek dip briz, was yu fes ɛn chɛst wit dɔmp klos, ɔ gɛt sɔm fresh briz na do. If yu nɔ drink rɔm, dat kin ɛp bak.
• Wiz: Fɔ mek yu nɔ blo fayn, tray fɔ drink ɛbul ti ɔ yuz inhala ɔ vaypa . If yu de smok, tray fɔ lɛf fɔ smok. Smok kin mek yu aywe dɛn wam mɔ.
• Daya: If dayarɛa na prɔblɛm fɔ yu, tɔk to yu dɔktɔ bɔt aw fɔ ridyus di frɛkuɛns ɛn i nɔ kin tranga. Spɛshal mɛrɛsin dɛn de we dɛn mek fɔ kɔntrol di dayarɛa we kin kam wit di sik we dɛn kɔl carcinoid syndrome. Dɔn bak, it dɛn we gɛt fat, we gɛt spays, ɛn it dɛn we gɛt dairy kin mek dis sik wɔs fɔ sɔm pipul dɛn. So tek tɛm wit wetin yu de it.

Ustɛm a fɔ go to dɔktɔ? / Ustɛm a fɔ go na imejensi rum?

If yu simptom dɛm fɔ carcinoid syndrome de wɔs, mek shɔ se yu go to dɔktɔ. If dɛn de trit yu fɔ NET, tɛl yu dɔktɔ if yu notis ɛni nyu chenj na yu bɔdi we kin fil lɛk NET simptom. Dɛn chenj ya nɔr gɛt fɔ du wit yu NET diagnosis, bɔt di bɛst we fɔ no fɔ tru na fɔ tɔk to yu dɔktɔ. Dɔn bak, if yu sik ɔr di sayd ɛfɛkt dɛm wae yu gɛt frɔm yu tritmɛnt wɔs, tɛl yu dɔktɔ.

Ustɛm fɔ go na wan Imejɛnsi Tritmɛnt Yunit (ETU) .

If dɛn nɔ trit di sik we dɛn kɔl carcinoid syndrome, di sik kin wɔs as tɛm de go ɛn i kin bi wan sik we kin mek pɔsin in layf de pan denja we dɛn kɔl ‘carcinoid crisis.’ So, go na ɔspitul imejensi dipatmɛnt wantɛm wantɛm if yu gɛt:

• If yu gɛt palpiteshɔn ɔ yu chɛst de pen.
• If yu gɛt siriɔs dayarɛa fɔ sɔm dez.
• If yu gɛt siriɔs bɛlɛ pen.
• If yu fil se yu dɔn fɔdɔm.
• If yu gɛt wata we yu fes, yu nɛk, ɛn yu chɛst we de flash wantɛm wantɛm (acute flushing).

Us kwɛstyɔn dɛn a fɔ aks mi dɔktɔ?

Carcinoid syndrome kin bi sayn fɔ se yu gɛt nyuroendocrine tumor (NET). So if yu gɛt kwɛstyɔn bɔt kansa sik, yu kin gɛt bɔku kwɛstyɔn bɔt NET. Na sɔm kwɛstyɔn dɛn we yu kin aks yu dɔktɔ:

• If a gɛt kansa sindrom, aw a go no if a gɛt nyuroɛndokrin tɔŋ?
• If a gɛt tumbu, usay i de na mi bɔdi?
• Wetin na di tritmɛnt fɔ mi tumbu?
• Wetin na di sayd ɛfɛkt dɛm we di tritmɛnt kin gɛt?
• Yu tink se di nyuroɛndokrin tɔŋ we mek a gɛt kansa sik kin wɛl ɔltogɛda?
• Yu tink se kansa sik kin kam bak afta dɛn dɔn trit mi nyuroɛndokrin tɔŋ?

Faynal Mɛsej fɔ Tek-Hom

Carcinoid Syndrome na wan sik we nɔ kin apin so ɔltɛm we kin apin to pɔsin we gɛt nyuroɛndokrin tɔŋ (NET). Bɔrku tɛm, pipul dɛm wae gɛt carcinoid syndrome dɔn ɔlrɛdi no se dɛn gɛt NET. Sɔmtɛm, pipul dɛn kin fɔs no se dɛn gɛt NET afta dɛn dɔn no se dɛn gɛt kansa sik.

Di bɛst pat na dat NET dɛn kin trit. Fɔ no se yu gɛt kansa na di fɔs tin fɔ no if yu gɛt kansa ɛn if na so, aw fɔ trit am. So, if dɛn dɔn no se yu gɛt kansa, nɔ fred fɔ tɔk to yu dɔktɔ ɛn aks wetin na di nɛks step fɔ kɔnfɔm if yu gɛt NET. De tin wae impɔtant pas ɔl na fɔ gɛt di sik ɛn trit yu kwik kwik wan.

Mɛmba se nɔto yu wangren de. Insay dis kayn tin, i rili impɔtant fɔ fala di dɔktɔ dɛn advays ɛn aks fɔ sɔpɔt frɔm yu famili.

` Karsinoyd sindrom, nyuroεndokrin tכmכro dεm, NET dεm, sεrotonin, simptom dεm, kεnsar, כmon dεm