Sɔntɛnde, if di sɔl ɔ sɔdiɔm we de na wi bɔdi nɔ bɔku, dat kin mek wi denja. Bɔt yu no se if wi inkrisayz dis sodium we dɔn go dɔŋ wantɛm wantɛm, i kin pwɛl wi bren? wan siriכs kכndyushכn we kin apin na dis kayn tεm dεn kכl am `Central Pontine Myelinolysis (CPM).` sכmtεm dεn kin kכl am bak `Osmotic Demyelination Syndrome (ODS).` Lε wi tכk bכt dis mכr ditayli, biכs dis na tin we wi כl nid fכ no.
Wetin na `Sɛntral Pɔntin Maylinɔlaysis (CPM)`? Fɔ tɔk am simpul wan...
fכ simpul wan, `Central Pontine Myelinolysis (CPM)` na di damej pan di nεv sεl dεm na di `Pons` εria na di midul pan wi bren stεm εn di protεktiv kכva we de rawnd dεm, we dεn kכl di `myelin sheath.` Tink am lεk di plastic kכva we de rawnd waya. dis maylin sεl de εp di nεv sεl dεm fכ travul fast fast.
Wi bren stem na wan pat we rili impɔtant na wi bɔdi. na di say we di infכmeshכn de travul bak εn go bifo bitwin wi spεnal kכd εn di big "tink" pat na di bren. I de ɛp bak fɔ kɔntrol impɔtant tin dɛn lɛk fɔ blo, fɔ digest, ɛn fɔ bit di at.
so, insay di kes fכ `CPM`, dis maylin sεt de pwεl, εn te go di nεv sεl dεm kin pwεl. Bɔku tɛm dis kin apin if di sodium lɛvɛl na wi bɔdi go ɔp wantɛm wantɛm, kwik kwik wan. dis risk kin kam spεshal wan we wi de trit lכw sodium na di bכdi (dis na wetin wi kin kכl `hyponatremia`).
CPM kin mek yu gɛt difrɛn kayn sayn dɛm. Dɛn tin ya na we di mɔsul dɛn wik, we i nɔ ebul fɔ waka, we i nɔ ebul fɔ tɔk fayn, ɛn we i de chenj di we aw i de biev. Bɔrku pipul dɛn kin wɛl kpatakpata, bɔt sɔm kin gɛt disabled fɔ lɔng tɛm. Sɔntɛm, i kin day.
Udat de pan risk pas ɔl fɔ gɛt dis `CPM` kɔndishɔn?
Infakt, ɛni sik ɔ kɔndishɔn we de ridyus di sɔdiɔm lɛvɛl na di bɔdi de mek di risk fɔ gɛt CPM bɔku. Pipul wae dɔn gɛt low sodium lɛvɛl fɔ pas 48 awa na dɛn kin gɛt di ay risk.
Di situeshɔn dɛn we men wan gɛt fɔ du wit `CPM` na:
- Fɔ yuse rɔm pasmak (`Alcohol use disorder`) : Dis na di men tin we kin mek yu drink rɔm.
- Liva transplant : Sɔdiɔm prɔblɛm kin apin ivin we di liva nɔ de wok fayn.
- Bɔn bad bad wan : Bɔn bad bad wan kin mek di wata ɛn sɔl na di bɔdi nɔ balans.
- Hyperemesis gravidarum (we dɛn kin vɔmit pasmak we dɛn gɛt bɛlɛ) : Sɔm mama dɛn kin gɛt bad bad vɔmit we dɛn gɛt bɛlɛ, we kin mek bak di sodium nɔ bɔku.
- Malnutrishɔn : Dɛn prɔblɛm ya kin apin ivin we pɔsin nɔ gɛt di rayt it ɛn drink.
Aw kכmכn dis kכndyushכn we dεn kכl `Sεntral Pontin Mayelinolysis`?
Fɔ tɔk tru, dɔktɔ dɛn nɔ kin ebul fɔ tɔk klia wan aw dis sik kin bɔku. Wan rizin na dat bɔrku pipul dɛm wae gɛt mild CPM nɔr kin sho sɔm kayn sik. Dat min se dɛn nɔ ivin no se dɛn gɛt di sik.
Bɔt dɛn kin si siriɔs kes dɛm fɔ CPM pan pipul dɛm wae de drink pasmak, pipul dɛm wae gɛt liva transplant, ɛn pipul dɛm wae gɛt ɔda siriɔs mɛrɛsin.
Wetin mek dis `Sɛntral Pɔntin Maylinɔlaysis` kin apin? Wetin na di tin dɛn we kin mek i apin?
as wi bin dכn tכk, di men kכz fכ `Central Pontine Myelinolysis` na we di sכdiכm lεvεl dεm de inkrεs kwik kwik wan. dis kin apin we dεn de trit di lכw sכdiכm lεvεl na di bכdi (`hyponatremia`).
Naw, luk, sɔdiɔm na impɔtant ilɛktrɔlayt fɔ wi bɔdi. Fɔ tɔk am simpul wan, sɔdiɔm de ɛp fɔ balans di wata we de insay ɛn ɔdasay na wi sɛl dɛn. If pɔsin drink pasmak, i kin gɛt sik na in liva, ɛn bɔku ɔda tin dɛn we kin mek i gɛt wɛlbɔdi, dat kin mek di sodium nɔ bɔku na di bɔdi. If dɛn nɔ trit dis sik we dɛn kɔl hayponatremia fayn, i kin mek pɔsin sik bad bad wan ɛn go na ɔspitul.
So, we yu de na ɔspitul, dɔktɔ dɛn kin kɔrɛkt dis smɔl sodium lɛvɛl bay we dɛn kin gi yu wan sɔl we dɛn kin put insay yu bɛlɛ (IV) . Bɔt if yu sɔdiɔm lɛvɛl go ɔp tumɔs kwik ya, na da tɛm de CPM kin apin.
Tink bɔt am lɛk wetin kin apin we yu tɔn bɔku wata wantɛm wantɛm pan plant we dɔn dray. Na sɔntin we pɔsin fɔ tek tɛm du. Na di sem tin kin apin fɔ kɔrɛkt di sodium lɛvɛl na di bɔdi.
Aw dis `Sεntral Pכntin Maylinכlaysis` kin apin? Wetin kin rili apin insay di bɔdi?
We di sɔdiɔm we de na yu blɔd go ɔp kwik kwik wan wantɛm wantɛm, di wata we de insay di nɛv sɛl dɛn kin kɔmɔt na di sɛl dɛn. dis dεn kכl am `osmotik shift` . Dis kin mek di nɛv sɛl dɛn nɔ gɛt wata , lɛk se dɛn de dray. dis wata we de dכn wata de pwεl di nεv sεl dεm εn di maylin sεl we de rawnd dεm. dis damej pan di maylin sεt dεn kכl am `myelinolysis` .
di nεv sεl dεm na di pons, we na wan pat pan di bren stεm, kin rili izi fכ dis kayn maylεnolaysis, we mek dεn kכl am sεntri pכntin maylεnolaysis.
Wetin na di difrεns bitwin `Sεntral Pכntin Mayεlinכlaysis (CPM)` εn `Ekstrapכntin Mayεlinכlaysis (EPM)`?
dis maylin dεm we dεn dכn pwεl nכ de apin כltεm na di pons nכmכ. sכmtεm, maylεnolaysis kin apin na כda pat dεm na di bren bak. dis kayn maylin dεm we de pwεl na do na di pons dεn kכl am εkstrapכntin maylinכlaysis (EPM) .
Bɔt, EPM nɔ kin bɔku. Na lɛk wan pan ɔl 4 pipul dɛm wae gɛt CPM (lɛk 25%) kin gɛt EPM bak.
Wetin na di simptom dɛm fɔ `Central Pontine Myelinolysis`?
di simptom dεm fכ CPM kin bigin insay fכ de dεm we dεn kכrekt di sכdiכm lεvεl kwik kwik wan. dis simptom dεm kin difrεn dipכnt pan usay na di bren di maylin dεm dεm dεn dכn apin εn aw bכku damej dכn apin. De men sayn wae yu kin si na:
- Di chenj wae de kam pan aw pɔrsin de biev: lɛk fɔ vɛks ɔr de vɛks wantɛm wantɛm.
- Kɔnfyushɔn: Fɔ fil lɛk se yu nɔ no natin, lɛk se yu fɔgɛt usay yu de ɛn ustɛm i de.
- I nɔ kin izi fɔ tɔk (dysarthria): Wɔd dɛn kin slɔp ɛn di tɔk nɔ kin klia.
- I nɔ izi fɔ swɛla (dysphagia): I nɔ izi fɔ swɛla it ɛn drink, fil lɛk se yu de chok.
- Facial paralysis: Wan say na di fes kin swɛt ɛn i kin stɔp fɔ wok fayn.
- di mכsul dεm we wik: Di limb dεm kin fil lεk se dεn de go sכmtεm.
- Lɔs fɔ balans ɛn kɔdineshɔn: I de stag we yu de waka, nɔ ebul fɔ ɔndastand tin dɛn fayn fayn wan.
- di mכsul dεm we nכ de muv εn trem (`Tremors`): di limb dεm de shek we dεn nכ de kכntro.
- di ay muvmεnt dεm we nכ de muv rεgulεr (`Oculomotor dysfunction`).
- Pakinsin: Yu kin shek, i nɔ kin izi fɔ tɔk, ɛn i kin at fɔ waka, we fiba di sik we dɛn kɔl Pakinsin.
- Kwadriparesis: Wik na ɔl di 4 an, leg, ɛn fut.
insay di kes dεm we rili siriכs, CPM kin mek wan kכndyushכn we dεn kכl `lכk-in sεndrכm`, we כl di mכsul dεm pas di ay mכsul dεm de paralayz. Dis min se di sikman kin tink ɛn muv in yay, bɔt i nɔ kin ebul fɔ tɔk ɔ muv in bɔdi. Dɛn kin fɔdɔm bak na kɔma ɔ day.
Aw dεn kin no dis kכndyushכn `Central Pontine Myelinolysis`? (Diagnosis) .
Fɔ no if yu gɛt CPM, yu dɔktɔ go du dɛn tin ya:
- Aks bɔt yu sayn dɛm: wetin yu de fil, aw lɔng yu dɔn gɛt dɛn prɔblɛm ya, ɛn ɔda tin dɛm.
- Dɛn kin luk fɔ di tin dɛm wae kin mek yu gɛt dis sik: tin dɛm lɛk aw yu sodium lɛvɛl bin tan lɛk wae dɛn bin de trit yu, ɛn if yu gɛt ɔda mɛrɛsin.
- MRI skan: MRI kin ɛp yu dɔktɔ fɔ si di say dɛn we dɔn pwɛl (lɛsin) na yu bren we maylinolysis kin mek. Bɔt sɔntɛnde, dɛn say ya we dɔn pwɛl nɔ kin si pan MRI te lɛk tu wiks afta di sayn dɛn bigin.
Wetin na di tritmɛnt dɛm fɔ `Central Pontine Myelinolysis`?
No spesifik, standad tritmɛnt nɔ de fɔ CPM. Di men gol fɔ tritmɛnt na fɔ kɔntrol di sayn dɛm. Fɔ ɛgzampul, dopaminergic drugs (drɔg dɛm wae de mek di dopamine lɛvɛl go ɔp) kin ɛp sɔmtɛm fɔ pipul dɛm wae gɛt dis sik wae de kam wit Pakinson (we de shek shek, i nɔr kin izi fɔ tɔk).
Sɔm dɔktɔ dɛn dɔn trit di kɔndishɔn we dɛn kɔl `CPM` bay we dɛn de put di sodium lɛvɛl dɔŋ bak, dɔn dɛn de inkrisayz am bak rili sloslo. Bɔt dis tritmɛnt we dɛn kin du nɔ kin wok fɔ ɔlman.
Aw fɔ protɛkt yusɛf frɔm `Sentral Pontine Myelinolysis`? (Prɛvenshɔn) .
Dis na di tin we impɔtant pas ɔl.
- If yu gɛt wan sik we kin mek yu bɔdi nɔ gɛt bɛtɛ sodium, na fɔ no bɔt am.
- If yu gɛt prɔblɛm wit yu rɔm, duya go to yu dɔktɔ fɔ ɛp yu. If yu drink rɔm, dat kin mek yu gɛt hayponatremia (we sodium nɔ bɔku). I kin mek bak di liva nɔ wok, we kin mek dɛn transplant di liva. Dis na di men tin dɛm we kin mek pɔsin gɛt CPM.
Dɔktɔ dɛn kin mek dɛn nɔ gɛt Sɛntral Pɔntin Maylinɔlaysis (CPM) bay we dɛn de fala di klinik gaydlayn dɛn we de naw fɔ mek di sɔdiɔm lɛvɛl go ɔp sef ɛn smɔl smɔl pan di wan dɛn we gɛt hayponatremia.
Yu tink se dɛn kin mɛn Sɛntral Pɔntin Maylinɔlaysis? Yu tink se dɛn kin chenj am?
Dis na prɔblɛm we bɔku pipul dɛn gɛt. Akɔdin to stɔdi dɛn we dɛn jɔs dɔn du, lɛk 94% pan di pipul dɛn we gɛt CPM kin liv. כlso, bitwin 25% εn 40% de mek ful rεkכvεshכn.
Bɔt, lɛk 25% pan di pipul dɛm wae gɛt CPM nɔr kin wɛl ɔl. Dɛn pipul ya kin nid sɔm sɔpɔt ɔlsay na dɛn layf. Tritmɛnt lɛk fɔ tɔk, ɔkupeshɔn tɛrapi, ɛn fyzikal tritmɛnt kin ɛp dɛn fɔ du tin dɛn we dɛn kin du ɛvride.
Aw fɔ liv wit di `CPM` sityueshɔn?
Yu dɔktɔ go gi yu di advays we yu nid. If yu fala da tritmɛnt plan de kɔrɛkt wan, yu go ebul fɔ kɔntrol di sayn dɛn we de ambɔg yu ɛvride layf.
Yu ɛn yu famili kin bɛnifit bɔku frɔm di savis dɛn we de sɔpɔt yu. Tɔk to yu dɔktɔ bɔt aw fɔ kia fɔ yu na os, sɔpɔt grup dɛn, ɛn ɔda tin dɛn.
Aw fɔ gɛt ɛp fɔ di sik we dɛn kɔl alcohol use disorder?
Dɔktɔ dɛn kin trit di sik we pɔsin kin gɛt we i de yuz rɔm wit bihayvya tɛrapi ɛn mɛrɛsin. Bɔku sɔpɔt grup dɛn de bak we de ɛnkɔrej ɛn ɛp fɔ gɛt akɔntabliti.
Pipul wae gɛt Alcohol Use Disorder kin gɛt tritmɛnt na ɔspitul, rɛzidɛshɔnal rihabiliteshɔn fasiliti, ɔr tru ɔutpatient savis.
Di fɔs tin we yu fɔ du fɔ mek yu wɛl frɔm di sik we yu de yuz fɔ drink rɔm na fɔ admit se yu gɛt prɔblɛm. We yu aks dɔktɔ fɔ ɛp yu, yu kin rili mek yu chans fɔ wɛl.
Di tin we impɔtant pas ɔl - mɛmba! (Mɛsej we dɛn kin tek go na os)
Sεntri Pכntin Maylinolaysis (CPM) na wan kכndyushכn we dεn kin rili avεnt. Dɔktɔ dɛn de fala di gaydlain dɛn we de naw fɔ tek tɛm ɛn tek tɛm inkrisayz di sodium lɛvɛl pan di wan dɛn we gɛt hayponatremia (lɔ sodium).
Yu kin ridyus yu risk, mɔ if yu gɛt prɔblɛm wit fɔ drink rɔm, bay we yu tek step fɔ stɔp. If yu nid ɛp, tɔk to yu dɔktɔ. Dɛn kin gi yu di sɔpɔt ɛn tin dɛm wae yu nid fɔ mek yu chenj yu layf ɛn gɛt wɛl bɔdi abit dɛm.
Mɛmba se, fɔ no na di big tin we go protɛkt wi!
` Sεntrεl Pכntin Mayεlinכlaysis, Bren, Nεv, Sכdiכm, Maylin, Alkol, CPM
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