Wetin na Choroid Plexus Carcinoma? Lɛ wi tɔk bɔt dis bren kansa we denja bɔt we nɔ kin bɔku!

Sɔntɛnde, we wi tink bɔt di sik dɛn we di wan dɛn we wi lɛk, mɔ wi smɔl pikin dɛn kin gɛt, wi kin fil big big lod ɛn fred, nɔto so? Tide wi go tɔk bɔt wan kayn kansa na yu bren we rili siriɔs, bɔt we nɔ kin apin so ɔltɛm . Nɔ fred wantɛm wantɛm we yu yɛri in nem. Bikɔs, fɔ no bɔt ɛni sik na big trɛnk fɔ bia wit am. So, lɛ wi tɔk ditayli bɔt dis Choroid Plexus Carcinoma.

Wetin na Choroid Plexus Carcinoma?

Fɔ tɔk am simpul wan, dis Choroid Plexus Carcinoma na kansa we de divɛlɔp insay wan spɛshal tisu we dɛn kɔl choroid plexus insay wi bren. Jɔs tink bɔt, difrɛn pat dɛn ɛn difrɛn kayn tisu dɛn de insay wi bren. dis choroid plexus tisu de insay di kכva dεm (ventrikl) insay di bren. lεk wata balכn, na dis choroid plexus tisu we de mεntal εp fכ mek sεribrospεnal fכluid (CSF) we de protεkt εn gi wi bren εn di spεnal kכd we de rכn dכn di spayna.

Dis na wan bad bad tumbu . Dis min se di sɛl dɛn we de insay de gro we dɛn nɔ ebul fɔ kɔntrol, dɛn kin gro kwik kwik wan, ɛn dɛn kin skata to ɔda say dɛn. dכkta dεn kin kכl dis bak grεd 3 choroid plexus tumor.'' dεn kin gro kwik kwik wan εn de tray fכ spre כlsay na di sεntri nεv sεstem'' (CNS) tru di CSF'' fכluid. Na dat mek sɔntɛnde fɔ trit dɛn kin tranga smɔl.

Aw dis sik kin bɔku?

Yu kin sɔprayz fɔ yɛri dis, bɔt dis sik we dɛn kɔl choroid plexus carcinoma na rili sik we nɔ kin bɔku . jכs tink, pan כl di 100 tכp dεm na di bren tכmכro, less dan 1% na choroid plexus tumor. tri kayn choroid plexus tכmכro dεm de. pan dεm, dis choroid plexus carcinoma na di rεst εn כnli kayn kεnsar, dat na di malignant tכp . I sɔri fɔ no se dis sik kin afɛkt pikin dɛn ɛn smɔl pikin dɛn mɔ .

Wetin na di sayn dɛm fɔ dis sik? Aw wi kin no am?

So, wetin na de sayn dɛm fɔ dis sik? Dis kin difrɛn difrɛn wan bay di sayz we di tumbu gɛt, usay i de na di bren, ɛn di pikin in ej. Bɔt, in jɔnal, sɔm sayn dɛn de we yu fɔ luk fɔ:

• Kɔnstant filin fɔ taya pasmak ɛn taya: I tan lɛk se di pikin nɔ de alayv, dɛn nɔ de rɔn rawnd ɛn ple lɛk aw dɛn bin de ple. I tan lɛk se dɛn de slip ɔltɛm.
• Ɛd we de at: Sɔntɛm yɔŋ pikin nɔ go ebul fɔ tɔk dis, bɔt wi kin no bay tin dɛn lɛk we dɛn ol dɛn ed, kray ɔltɛm, ɛn nɔ gri fɔ it.
• I kin vɛks ɔ i kin mek i vɛks: I kin bi se smɔl pikin kin vɛks ɛn i nɔ kin izi fɔ mek i kɔrej am. Sɔntɛm dɛn kin traŋa pas aw dɛn bin de du trade.
• Nɔs ɛn vɔmit: Dis kin wɔs, mɔ na mɔnin.
• Sɔm pat dɛn na di bɔdi kin swɛla ɔ wikɛd: Wan an ɔ yu leg kin fil lɛk se i dɔn swɛla ɔl.
• Seizure: I kin gɛt kɔnvulshɔn wantɛm wantɛm ɛn nɔ kin no natin.
• Prɔblɛm fɔ si: Yu kin si blɔk vishɔn ɔ yu kin si tu pikchɔ dɛn wan tɛm (diplopia). Smɔl pikin kin rɔb in yay ɔltɛm ɔ i nɔ kin izi fɔ mek i pe atɛnshɔn.
• di ed saiz we big: pan yכŋ pikin dεm, di ed kin big as di prεshכn insay di bren de bכku biכs di bon dεm na di sכkul nכ fulכp.

Nɔr frayd fɔ gɛt dis sik jɔs bikɔs yu gɛt wan ɔr tu pan dɛn sayn ya. Bɔt if dɛn sik ya kɔntinyu, i go fayn fɔ mek yu go to dɔktɔ fɔ tru .

Wetin mek dis kayn sik kin apin? Wetin na di kɔz?

Infakt, i nɔ kin izi fɔ mek dɔktɔ dɛn tɔk di rayt tin we mek sɔm pipul dɛn kin gɛt choroid plexus carcinoma. Bɔku tɛm, ɛni kansa kin kam we wan pan di jin dɛn we de na wi bɔdi chenj, we wi kin kɔl muteshon. Dis jεnεtik mכtεshכn de mek di hεlty sεl dεm bi kεnsar sεl dεm εn de mכltipכl we dεn nכ ebul fכ kכntrol, gro to tכmכro, εn sכmtεm dεn de spre כlsay na di bכdi.

Ɛni risk factor de wae kin afɛkt dis?

enibodi kin divεlכp dis kכndyushכn we dεn kכl choroid plexus carcinoma. Bɔt dɛn dɔn si se sɔm tin dɛm (wi kin kɔl dɛm risk factors) kin mek di chans fɔ gɛt am bɔku. Lɛ wi si wetin dɛn bi:

• Aicardi syndrome: Dis na wan sik wae de kam wit jεnεtiks wae nɔr kin apin. di pikin dεm we dεn bכn wit dis kכndyushכn gεt sכm abnכmal tin dεm na di bren divεlכpmεnt, we de mek dεn gεt kכroyd pleks tכmכro. Dis nɔ kin bi tin we pɔsin kin gɛt frɔm dɛn mama ɛn papa.
• Li-Fraumeni syndrome: Dis na wan sik bak we nɔ kin apin na di jɛnɛtiks. Pipul wae gɛt dis sik kin gɛt difrɛn kayn kansa. Bɔku tɛm dis kin apin bikɔs ɔf wan chenj we di jin chenj we kin kɔmɔt frɔm wan mama ɔ papa to di pikin.
• Bayolojikal sɛks: Pan ɔl we di rayt rizin nɔ klia, sɔm statystik dɛn sho se uman dɛn kin gɛt dis sik smɔl.

Aw dɔktɔ dɛn kin no bɔt dis sik? (Diagnosis) .

So, aw dɔktɔ dɛn kin kɔnfɔm if yu gɛt choroid plexus carcinoma? Dɛn kin du dis bay we dɛn kin tek tɛm lisin to yu sik dɛn, du ɛgzam fɔ yu bɔdi, ɛn afta dat dɛn kin du difrɛn tɛst dɛn. Dɛn tɛst ya kin difrɛn difrɛn wan bay yu ej, ɔr yu pikin in ej:

• Kɔgnitiv tɛst: Dis kin tɛst aw yu de wok fayn fayn wan, lɛk fɔ mɛmba, fɔ pe atɛnshɔn, ɛn fɔ ebul fɔ lan.
• Wan kɔmplit nyurolɔjik ɛgzam: Dis go chɛk fɔ si, yɛri, balans prɔblɛm, riflɛks, ɛn kɔdineshɔn fɔ difrɛn pat dɛn na di bɔdi.
• MRI (Magnetic Resonance Imaging) skan fɔ di bren ɔ ɔda imej tɛst (lɛk CT skan): Bɔku tɛm dis na di tɛst we impɔtant pas ɔl. i kin sho if eni tכmכro de na di bren, aw big dεn de, usay dεn de, εn if eni kכndyushכn de we dεn kכl haydrosεfalus (we de bכku fכ sεribrospεnal fכluid (CSF) na di bren kכva, we de mek di prεshכn go כp).
• DNA tεst (jεnεtik tεst): dεn kin du dis tεst fכ si if εni jεnεtik chenj de we kכnεkt wit kכndishכn dεm lεk di Li-Fraumeni sεndrכm we wi bin dכn tכk bכt כ Aicardi sεndrכm.
• spεnal tap (lumbar pancture): Dis involv fכ put wan tin nidul insay di lכw bכk εn tek sכm sכm sεmpl fכ CSF. Dɔn dɛn kin sɛn am na lɛbɔtri fɔ mek dɛn tɛst am fɔ si if i gɛt kansa sɛl dɛn.

Wetin na di tritmɛnt dɛm fɔ dis?

If dɛn kɔnfyus se yu gɛt tumbu lɛk dis, wetin yu go du nɛks? Bɔku tritmɛnt dɛn de we yu kin gɛt. Di men wan na ɔpreshɔn .

• Ɔpreshɔn: Nyurosɔjɔn dɛn kin du ɔpreshɔn pan di bren fɔ pul di tumbu ɔlsay as dɛn ebul. Dis na ɔpreshɔn we rili kɔmpleks. dεn tek wan sכm pat pan di tכmכro we dεn pul (bayopsi) εn sεn am na labכtכri fכ kכnfכm if na choroid plexus carcinoma כ כda kayn.

If dis bayɔpsi kɔnfɔm choroid plexus carcinoma, ɛn dɛn nɔ ebul fɔ pul di tumbu ɔl, ɔ if di kansa dɔn skata, yu ɔ yu pikin kin nid ɔda tritmɛnt. Dɛn tin ya na:

• Kimotɛrapi: Dis kin min fɔ gi di bɔdi difrɛn kayn mɛrɛsin fɔ kil di kansa sɛl dɛn. Dɛn mɛrɛsin ya kin kil di kansa sɛl dɛn we de sheb kwik kwik wan.
• rεdyushכn tεrapi: Dis de yuz ay-εnεji rayt (e.g. X-ray) fכ tכk εn pwεl di kεnsar sεl dεm.

Dɛn kin yuz wan ɔ mɔ pan dɛn tritmɛnt ya togɛda. Na wan tim we gɛt spɛshal dɔktɔ dɛn kin disayd dis, ɛn dɛn kin tink bɔt bɔku tin dɛn lɛk aw di pɔsin de fil ɛn aw di tumbu de.

Wetin na di prɔblɛm dɛn we kin apin afta dɛn dɔn du di ɔpreshɔn?

Jɔs lɛk ɛni ɔpreshɔn, smɔl chans de fɔ mek prɔblɛm dɛn apin afta dɛn dɔn ɔpreshɔn di bren. Pan ɔl we i nɔ kɔmɔn, sɔm pan di tin dɛn we pɔsin kin si sɔntɛnde na:

• Blɔd ɔ swel na di bren.
• I nɔ izi fɔ tink, kɔnfyushɔn ɔ delirium.
• Ed we de at we nɔ de chenj.
• Infekshɔn na di say we dɛn de du di ɔpreshɔn.
• Di mɛmori lɔs ɔ i nɔ kin izi fɔ tɔk.

Dɔktɔ dɛn go tɛl yu bɔt dɛn tin ya bifo tɛm.

Dɛn de mek nyu tritmɛnt fɔ dis sik?

Yɛs! Mɛdikal sayɛns de go bifo ɛvride. So, risach de kɔntinyu fɔ fɛn nyu, mɔ ifektiv tritmɛnt fɔ dis sik, choroid plexus carcinoma. Sɔm pan dɛn kin stil de na di risach stej (clinical trial). Na sɔm ɛgzampul dɛn ya:

• Immunotherapy: Dis na wan we we rili intrestin. I min fɔ mek wi yon imyun sistɛm (di sistɛm we de protɛkt wi frɔm sik dɛn) ɛn gi am mɛrɛsin dɛn we de ɛp am fɔ fɛn ɛn pwɛl di kansa sɛl dɛn.
• Targeted therapy: Dis kin min fɔ gi drɔgs wae de target sɔm kayn chenj dɛm na yu jɛnɛtiks wae de mek yu gɛt kansa ɛn wae de afɛkt ɔl dɛn chenj dɛm de. Dis kin mek di sɛl dɛn we gɛt wɛlbɔdi nɔ kin pwɛl bɛtɛ.

Yu kin lan mɔ bɔt dɛn nyu tritmɛnt ya bay we yu tɔk to yu dɔktɔ.

Aw i tan lɛk fɔ wɛl afta dɛn dɔn trit am?

De tɛm wae yu kin tek fɔ wɛl afta yu dɔn gɛt tritmɛnt, inklud wae yu kin go bak na woke ɔr skul, kin dipen pan sɔm tin dɛm. Na sɔm pan dɛn:

• Yu ej ɛn ɔl yu wɛlbɔdi.
• Di say we di tumbu de, di sayz we i gɛt, ɛn ɔmɔs tumbu dɛn de.
• If yu bin gɛt ɔda tritmɛnt lɛk kemotɛrapi ɔ redyushɔn tɛrapi, dɛn ifɛkt.

So, i impɔtant fɔ fala yu dɔktɔ in instrɔkshɔn dɛn di rayt we . fכ mכnitor if di hilin prכsεs de go fayn, dכkta dεm go aks yu bכku tεm fכ du bren imaging tεst (e.g. MRI scans). Fɔ du ɔltin kɔrɛkt wan rili impɔtant fɔ mek yu wɛl kwik kwik wan.

Wetin na di prɔgnosis wit dis sik?

Dis kwɛstyɔn na di big big lod we de pan bɔku pipul dɛn maynd. Di luk fɔ choroid plexus carcinoma, dat na di chans fɔ wɛl ɛn fɔ liv lɔng, kin difrɛn frɔm wan pɔsin to ɔda pɔsin. Bɔku impɔtant tin dɛn de we kin afɛkt am:

• Di pɔsin in ej (di rizɔlt kin difrɛn fɔ yɔŋ pikin dɛn).
• Di pɔsin in ɔl wɛlbɔdi stetmɛnt.
• If dɛn pul di wan ol tumbu we dɛn de du di ɔpreshɔn, ɔ na wan pat pan am nɔmɔ. (If dɛn kin pul di tumbu kpatakpata, di lukin-grɔn kin rili fayn.)

Dɔn bak, dɛn tin ya kin afɛkt di we aw pipul dɛn de si tin bak:

• if di tכmכro kam bak afta dεn כpεrayshכn כ כda tritmεnt dεm (rεkכrεshכn).
• If di kansa spred (metastasizes) frɔm di say we i bin de fɔs to ɔda pat dɛn na di bɔdi, fɔ ɛgzampul, di spɛnal kɔd.

Nɔto ɔlman na di sem, so i bɛtɛ ɛn kɔrɛkt fɔ aks yu mɛdikal tim wetin fɔ ɛkspɛkt bay yu kɔndishɔn.

stεdi, di כvala fayv ia sכvayv rεt fכ choroid plexus carcinoma de bitwin 40% εn 60%. Dis min se pan 10 pipul dɛm wae dɛn no se gɛt dis sik, 4 to 6 go liv fɔ fayv ia ɔr mɔr. כltu, fכ pכsin we gεt di jεnεtik kכndishכn we wi bin dכn tכk bכt Li-Fraumeni sεndrכm, dεn se dis pasεnshכn de lכs lεk 30 %.

Nɔ mek yu fred wit dɛn statystik ya. Dis na jɔs avrej. Ɔlman in kɔndishɔn, aw i de biev we dɛn de trit am, ɛn aw i de fɛt difrɛn. We dɛn de go bifo pan mɛrɛsin sayɛns, dɛn tin ya de bɛtɛ ɛvride.

Ustɛm wi fɔ rili go to dɔktɔ?

If yu ɔ yu pikin kɔntinyu fɔ gɛt wan ɔ mɔ pan di sik dɛn we wi dɔn tɔk bɔt, mɔ if yu si ɛni wan pan dɛn sik ya, yu fɔ rili go to dɔktɔ we sabi du di wok ɛn yu nɔ fɔ west ɛni tɛm :

• Di chenj dɛn we de apin klia wan na di we aw pɔsin de biev. Fɔ ɛgzampul, kɔnfyushɔn wantɛm wantɛm, vɛks pasmak, agyumɛnt.
• I nɔ kin izi fɔ yu fɔ blo.
• I nɔ izi fɔ waka, i nɔ de balans igen.
• Di sik dɛn we kin mek pɔsin sik wantɛm wantɛm (Seizures).
• Ed pen we rili bad, we pɔsin nɔ go ebul fɔ bia.
• Di chenj dɛn we pɔsin kin si wantɛm wantɛm na di we aw i de si ɔ we i de tɔk.

Wetin na di impɔtant kwɛstyɔn dɛn we wi fɔ aks di dɔktɔ?

We yu go to yu dɔktɔ, yu kin aks kwɛstyɔn dɛn lɛk dis fɔ mek yu ɔndastand yu sik klia wan. Nɔ fred fɔ aks ɔl wetin de na yu maynd:

• "Dɔkta, ɛksaktɔli us kayn bren tumor mi/mi pikin gɛt?"
• "Wetin na di bɛst tritmɛnt fɔ dis? Uswan pan dɛn fit mi/mi pikin pas ɔl?"
• "Wetin na di poshubul sayd effekt afta tritmɛnt?"
• "Aw ɔltɛm mi/mi pikin go nid fɔ gɛt tɛst lɛk imaging skan?"
• "Wetin na mi/mi pikin in lukin-grɔn wit dis kɔndishɔn?"

Wan wɔd to di famili, mɔ to di mama ɛn papa...

We dɛn no se yu pikin gɛt choroid plexus carcinoma, i nɔmal fɔ fil lɛk se yu wan ol wɔl dɔn kam krash dɔŋ. Ɔltin kin bigin fɔ apin kwik kwik wan. Yu go mit wan big tim fɔ dɔktɔ dɛn, we gɛt nyu nyurolɔjis ɛn ɔnkɔlɔjis dɛn. Yu kalenda go ful-ɔp wit tɛst, dɔktɔ apɔntinmɛnt, ɛn ɔpreshɔn. Afta di fɔs gladi gladi, yu go gɛt fɔ wet fɔ lɔng tɛm fɔ mek di rizɔlt kam bak, fɔ di nɛks step dɛm. Dis tɛm we yu de wet kin rili strɛs ɛn i nɔ kin izi fɔ yu.

Bɔt, ɛvri smɔl tɛm we yu kin spɛn wit yu pikin insay da tɛm de, i valyu. Lan nyu lullaby fɔ mek i slip, wach in fav katun ɔ fim dɛn togɛda, tray fɔ fɛn nyu tin we una go du togɛda we go mek una gladi.

I at fɔ liv insay di prɛsɛn mɔnt, de wɔri bɔt di nɛks skan, di nɛks tɛst ripɔt. Bɔt ilɛk wetin da skan ɔ ripɔt de sho, yu kin put yu wɔri ɛn fred dɛn na kɔna ɔltɛm ɛn gladi fɔ di valyu tɛm we yu spɛn wit yu pikin. Nɔto yu wan de. Bɔku pipul dɛn de we go ɛp yu ɛn lisin to yu.

Fɔ dɔn, di tin dɛn we impɔtant pas ɔl fɔ mɛmba (Take-Home Message) .

Okay, so lɛ wi sɔmariz di impɔtant tin dɛm we yu nid fɔ kip na yu maynd bɔt dis Choroid Plexus Carcinoma'' we dɛn dɔn tɔk bɔt fɔ lɔng tɛm?

• Choroid Plexus Carcinoma na wan kayn kansa we nɔ kin bɔku bɔt we kin gro kwik kwik wan we kin kam na di tisu na di bren we dɛn kɔl choroid plexus. I kin afɛkt yɔŋ pikin dɛn ɛn bebi dɛn mɔ .
• If yu gɛt wan ɔ mɔ tin dɛn lɛk we yu de slip pasmak, yu ed we de at ɔltɛm, yu de vɔmit ɔltɛm, yu de fil bad, ɔ yu gɛt prɔblɛm wit yu yay bikɔs ɔf tin dɛn we yu nɔ no bɔt, nɔ west yu tɛm ɛn go to dɔktɔ wantɛm wantɛm .
• Di men tritmɛnt dɛn we dɛn kin yuz na ɔpreshɔn, kemotɛrapi, ɛn redyushɔn tɛrapi . Sɔntɛnde, dɛn kin yuz pas wan pan dɛn tritmɛnt ya.
• Pan ɔl we dis na tranga ɛn tranga waka, if yu ɔ sɔmbɔdi na yu famili de gɛt dis prɔblɛm, mɛmba se nɔto yu wangren de . Gɛt tru dis wit di sɔpɔt we yu mɛdikal tim, yu fambul, ɛn padi dɛn de gi yu. Fɔ kɔntinyu fɔ gɛt gud maynd ɛn fɔ strɔng rili impɔtant pan dis fɛt.

Wi op se dis infɔmeshɔn go fayn fɔ yu. Gud wɛlbɔdi fɔ ɔlman!