Prɔblɛm de wit yu kɔnia? Lɛ wi lan bɔt kɔnia distrofi!

Yu kin fil se yu yay nɔ de shayn? Sɔntɛnde, i nɔ kin izi fɔ yu fɔ luk layt? Ɔ yu kin fil ɔltɛm se sɔntin nɔ fayn na yu yay? Sɔntɛnde, dɛn tin ya kin bi sayn fɔ wan sik we gɛt fɔ du wit di kɔnia na di yay. Tide wi go tɔk bɔt wan pan dɛn kayn tin ya, "Corneal Dystrophy". Nɔ wɔri, wi go tɔk bɔt dis simpul wan, di we we yu go ɔndastand.

Wetin na Kɔnia Distrofi?

Fɔ tɔk am simpul wan, kɔnia distrofi na wan jɛnɛral wɔd fɔ wan grup we de afɛkt di kɔnia , di transparent pat na yu yay. I pas 20 difrɛn kayn sik dɛn we de ɔnda dis kategori. Dɛn kayn distrofi ya kin mek chenj ɔr pwɛl di tisu dɛm na di kɔnia. I tan lɛk se yu gɛt smɔl smɔl spat ɔ strek dɛn na klia glas we yu nɔ go ebul fɔ si klia wan we yu luk insay . If dis damej kin kam bad bad wan, yu kin gɛt chenj na yu yay ɛn ivin yu nɔ kin si fayn igen.

di imכtant tin na dat dεn kכnia distrofi ya na jεnεtik kכndishכn dεm. Dat min se na di chenj dɛn we de apin na wi DNA kin mek dɛn . Sɔm chenj dɛn we yu kin gɛt frɔm yu mama ɛn papa. Ɔda wan dɛn kin apin we yu nɔ bin de ɛkspɛkt, bay dɛnsɛf. Sɔm kayn sik kin apin fɔ rizin dɛn we masta sabi pipul dɛn stil nɔ ɔndastand gud gud wan.

Sɔm kayn kɔnia distrofi de?

Yes, dεn kin kכl dεm akɔdin to aw dεn de afekt di difrεn layεr dεm na di kכnia. Men wan na dɛn wan ya:

• di wan dεm we de afekt di כta layεr dεm na di kכnia (εpitel εn sכbεpitεlial).
• di wan dεm we de afekt di כta εn midul layεr dεm na di kכnia (Epithelial-stromal).
• di wan dεm we de afekt di midul layεr na di kכnia (Stromal).
• di wan dεm we de afekt di layt we de insay di kכnia (endothelial).

Naw lɛ wi luk ɛni wan pan dɛn kayn dɛn ya smɔl mɔ.

di εpitεlial εn sכbεpitεlial kכnia distrofi dεm

dis na sik dεm we de afekt di tכp layεr dεm na di kכnia. Sɔm ɛgzampul dɛn na:

• Epitεlial bεsmεnt mεmbran distrofi
• di εpitεlial rεkכrεnt εroshכn distrofi dεm (tri sכbtayp dεm de bak) .
• Distrofi we tan lɛk jelatin we de drɔp
• Lisch epitel distrofi we de mek pɔsin gɛt di sik
• Meesmann distrofi we gɛt di sik
• Subεpitεlial mכsinכs distrofi

Bɔku pan dɛn distrofi ya kin apin we dɛn smɔl . כltu, di εpitεlial bεsmεnt mεmbran distrofi kin apin (pan כl we nכto כltεm) we i big. Di ɔda wan na kɔnia distrofi we tan lɛk jelatin drɔp.Dis kin apin pan ɛni ej bifo i ol 20 ia.

Epitεlial-stromal distrofi dεm

dis dεm de afekt כl tu di כta layεr na di kכnia εn di midul layεr כnda am.

• Granular kɔnia distrofi (tayp 1 ɛn 2) .
• Lattice corneal dystrophy (dis tu gεt sכbtayp dεm εn difrεn vεryut dεm) .
• Distrofi we Reis-Bückler bin gɛt
• Thiel-Behnke distrofi we gɛt di sik

Ɔl dɛn tin ya kin apin mɔ we dɛn smɔl . Lattice corneal dystrophy tayp 1 kin apin as let as 20 ia ol.

Distrofi dɛn we de na di stromal

dis dεm kin afekt mεntal wan di midul, tik layεr na di kכnia.

• Makula distrofi we gɛt di sik
• Schneider kristalin distrofi we gɛt di sik
• Distrofi we pɔsin kin gɛt we i bɔn
• Flek distrofi we gɛt di sik
• Posita distrofi amɔrfɔs
• Distrofi we bin de bifo di Dɛsmɛt
• Sɛntral klawdi distrofi fɔ François

Stromal dystrophies kin afɛkt pikin dɛn . Bɔt tu pan dɛn tin ya kin apin as yu de ol. Schneider kכnia distrofi kin divεlכp as let as i ol 30 ia, εn prε-Descemet kכnia distrofi kin divεlכp afta i rich 30 ia.

εndoteyl kכnia distrofi dεm

dis na sik dεm we de afekt di rili dilik layεr insay di kכnia.

• Fuchs εndoteyl distrofi
• Posita polimכrf distrofi
• Distrofi we pɔsin kin bɔn wit in bɔdi
• X-linked εndoteyl distrofi

pan כl di kכnia distrofi dεm, Fuchs εndoteyl kכnia distrofi na di wan we kכmכn pas כl , we de mek 39% pan כl di kכnia transplant dεm we dεn du na Amɛrika.

Wetin na di sayn dɛm fɔ kɔnia distrofi?

Di sayn dɛm fɔ kɔnia distrofi kin difrɛn difrɛn wan fɔ di patikyula kayn we yu gɛt. Sɔm pipul dɛn nɔ kin gɛt ɛni sayn atɔl . We di sayn dɛn kin sho, dɛn kin afɛkt ɔl tu di yay dɛn ɛn smɔl smɔl dɛn kin wɔs as tɛm de go.

Imajin se yu kɔnia tan lɛk glas we shep fayn fayn wan, we klia, ɛn we nɔ gɛt wan bɔt. Bɔt di kɔnia distrofi kin chenj dat. pan bכku pan dεn kכndyushכn ya, nyu tisu dεm de gro pan di kכnia, כ i de bכku na say dεm we i nכ fכ bכku. Dɔn, instead fɔ luk tru klia glas, i tan lɛk se yu de luk tru ol glas we gɛt fɔlt ɛn we dɔn blo. I at fɔ si tru dat, nɔto so?

semweso, nyu tisu fכmeshכn כ akyumyuleshכn de mek i at fכ si tru di layεr dεm we afekt na di kכnia. Dis na di rizin we mek pipul dɛn we gɛt kɔnia distrofi nɔ kin si fayn ɔ we gɛt fɔg .

Di sayn dɛm wae kin kam pan pɔrsin na dɛn wan ya:

• Visual acuity loss: Dis kin apin we di say we di kɔnia de chenj ɔ i nɔ de wɛl fayn fayn wan. Dis min se yu nɔ kin si klia wan ilɛksɛf yu wɛr glas ɔ kɔntakt lens.
• Kɔnia haz: Dis kin mek yu yay tan lɛk klawd. Bɔrku tɛm dis na rεsidyual ifekt wae de damej ɔr chenj na di kɔnia.
• Fɔrin bɔdi sɛns: I kin tan lɛk se sɔntin dɔn stɔp na yu yay , bɔt we yu luk, yu nɔ go ebul fɔ fɛn ɛnitin.
• Ay pen ɔr yay iritashɔn: Dɛn sayn ya kin no mɔr we yu wek afta yu dɔn lɔk fɔ lɔng tɛm, fɔ ɛgzampul we yu wek na mɔnin.
• Layt sɛnsitiviti (Photophobia): Dis min se brayt layt nɔ kin bia ɛn i kin mek i nɔ fil fayn ɔ i kin mek i fil pen.
• Wata yay (Epiphora): If yu yay fil dray, dis kin bi bikɔs yu kray wata de tray fɔ mek mɔ kray wata fɔ kɔmpɛns.
• Nystagmus: Dɛn nɔ kin kɔntrol di ay muvmɛnt kwik kwik wan frɔm wan say to di ɔda say ɔ insay wan sɛkɔral patɛn.

Wetin kin mek di kɔnia distrofi?

Ɛni wan pan dɛn difrɛn kayn kɔnia distrofi ya gɛt fɔ du wit di tin dɛn we de mek pɔsin gɛt jɛnɛtiks . dis kin bi "de novo" chenj dεm (we min se dεn kin apin randomly na yu bכdi) כ dεn kin gεt frכm wan כ yu tu mama εn papa.

Sɔm difrɛns dɛn we dɛn kin gɛt frɔm dɛn mama ɛn papa kin nid wan kɔpi nɔmɔ fɔ di jin frɔm wan mama ɔ papa. כda vεryushכn dεm nid tu kכpi fכ di mutated jin, wan frכm εvri mama εn papa. Dɔn bak, sɔm kayn kɔnia distrofi stil de, ɛn dɛn nid fɔ du mɔ risach fɔ no us patikyula jɛnɛtik difrɛns dɛn kin mek dɛn gɛt am.

Udat de pan denja pas ɔl fɔ gɛt dis sik?

Bɔrku pan di kɔnia distrofi nɔr kin afɛkt pipul dɛm difrɛn we bay dɛn rays ɔr man ɔ uman. di onli eksepshכn na Fuchs εndoteyl kכnia distrofi.Bɔku patikyula tin dɛn de we kin mek i gɛt prɔblɛm:

• Ras: Wait pipul dɛn kin gɛt am mɔ.
• Ej: Pipul wae dɔn pas 30 ia kin gɛt dis sik.
• Jɛnda: Uman dɛn kin gɛt am mɔ.

Wetin na di prɔblɛm dɛn we kin apin we pɔsin gɛt kɔnia distrofi?

Dɛn tin ya we kin fɔdɔm ɔnda di ɔmbrela fɔ di kɔnia distrofi, kin afɛkt di we aw layt de pas na yu kɔnia. Dis kin mek di klin we yu kɔnia klia kin go dɔŋ, ɛn dis kin mek di layt we de pas insay am nɔ fayn. Dis min se di kɔnia distrofi kin mek pɔsin nɔ ebul fɔ si bɛtɛ , bɔt i nɔ kin mek pɔsin blaynd ɔl .

Bɔt, we pɔsin nɔ de si bɛtɛ igen, dat kin bi siriɔs prɔblɛm. I kin afɛkt di we aw yu ebul fɔ drayv, rid, ɛn du bɔku wok dɛn ɛvride.

Aw dɛn kin no se pɔsin gɛt kɔnia distrofi?

Wan ay spɛshal dɔktɔ, ilɛksɛf na ɔftalmɔlɔjis ɔ optometrist, kin no se i gɛt kɔnia distrofi. Dɛn kin yuz bɔku tin dɛn ɛn difrɛn we dɛn fɔ du dat. Di pat we impɔtant pas ɔl na fɔ chɛk yu yay , mɔ fɔ ɛgzam fɔ slit lamp . Wan slit lamp ɛgzam min fɔ luk insay yu yay wit spɛshal maykroskɔp. Dis kin mek dɔktɔ dɛn si ɛni chenj ɔ damej we kin gɛt fɔ du wit kɔnia distrofi.

Ɔda tɛst dɛn we yu ay spɛshal pɔsin kin yuz na:

• di tכpografi fכ di kכnia: dis de mek wan "map" fכ di sכfa fכ yu kכnia. i de sho if eni εria dεm de na di kכnia sεf we hכy כ lכw pas di εria dεm we de rawnd.
• Pachymetry: Dis de mek yu kɔnia tik. dis kin εp fכ no di prכblεm dεm na di dip layεr dεm na di kכnia (lεk εndoteyl distrofi).
• Jɛnɛtik tɛst: Dis kin min fɔ tek wan sɛmpul pan yu saliva ɔ blɔd ɛn luk fɔ patikyula chenj dɛn na DNA . Dis kin ɛp fɔ kɔnfɔm di patikyula kayn kɔnia distrofi we yu gɛt.
• Optical Coherence Tomography (OCT): Pan ɔl we dɛn kin yuz dis fɔ luk yu retina, dis tɛst kin gi yu bak valyu skan fɔ yu kɔnia. Dis kin fayn mɔ we yu de plan sɔm tritmɛnt dɛn fɔ di kɔnia.
• Kɔnia bayɔpsi: Wan ay spɛshal dɔktɔ kin tek wan smɔl tisu sɛmpul frɔm yu kɔnia ɛn sɛn am to lab fɔ mek dɛn tɛst am. Patɔlɔjis go analayz di sampul fɔ no if yu gɛt kɔnia distrofi ɛn if na so, us kayn. Dis tɛst nɔr kin rili kɔmɔn fɔ kɔnia distrofi, bɔt i kin ɛp fɔ no di sik.

Dɛn kin du ɔda tɛst dɛn dipen pan yu sik ɛn ɔda tin dɛn. Yu ay spɛshal dɔktɔ kin tɛl yu mɔ bɔt ɔda tɛst dɛn we dɛn kin advays.

Aw dɛn kin trit kɔnia distrofi?

Bɔrku we de fɔ trit kɔnia distrofi. di tritmεnt de dipכnt pan di layt we di kכnia afekt εn aw di kכndyushכn de siriכs.

Bikɔs di tritmɛnt dɛn we yu kin gɛt kin difrɛn, yu yay dɔktɔ na di bɛst say fɔ no bɔt di tritmɛnt dɛn we yu kin gɛt. Dɛn kin ɛksplen to yu di ditel dɛm fɔ di tritmɛnt opshɔn dɛm, di prɔblɛm dɛm wae kin kam, di sayd ɛfɛkt dɛm, ɛn ɔda ditel dɛm.

Na sɔm pan di men we dɛn fɔ trit am:

Tritmɛnt dɛn we dɛn kin put pan pɔsin in bɔdi

Dɛn tin ya kin pe atɛnshɔn fɔ trit di sayn dɛm ɛn di tin dɛm we kin apin to di say we yu kɔnia de. Ɛgzampul dɛn:

• Aydrop ɔ ɔntmɛnt we gɛt mɛrɛsin: Dɛn tin ya kin trit sɔm sayn dɛm lɛk pen, fil fɔ gɛt sɔntin na yu yay, ɛn fɔ dray.
• Antibayɔtik: Dɛn tin ya kin ɛp fɔ mek yu nɔ gɛt di sik if yu kɔnia dɔn pwɛl ɛn yu kin gɛt smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl.
• Spɛshal kɔntakt lɛns dɛn: Jɔs lɛk di kɔntakt lɛns dɛn we dɛn kin yuz ɔltɛm, dɛn kin wɛr dɛn tin ya na di say we di kɔnia de. Di men difrɛns na dat dɛn kin ɛp yu kɔnia fɔ wɛl ɛn mek yu nɔ pwɛl mɔ.

Fɔtotɛrapitik keratektomi (PTK) .

fכto tεrapi kεratektכmi (PTK) involv fכ pul pat dεm na di kכnia we dεn de yuz wan lεzεr bim we dεn tכn fayn fayn wan. Yu ay spɛshal dɔktɔ kin ebul fɔ tɔch di say dɛn we dɔn pwɛl ɛn pul di say dɛn we dɔn pwɛl.

Kɔnia transplant

If yu kɔnia chenj ɔ damej bad bad wan fɔ afɛkt yu yay, fɔ transplant kɔnia kin bi sɔntin we yu go ebul fɔ du. Dɛn ɔpreshɔn ya kin min fɔ chenj yu kɔnia tisu wit nyu tisu frɔm pɔsin we dɔn day. Dɛn tin ya kin bi ful ɔ pat pan transplant.

Wetin yu kin ɛkspɛkt if yu gɛt kɔnia distrofi?

If yu gɛt kɔnia distrofi, wetin yu kin ɛkspɛkt kin difrɛn smɔl. Bɔrku pipul dɛn kin gɛt wan pan dɛn sik ya, bɔrku tɛm bifo dɛn ol 20 ia.

Kɔnia distrofi kin bi wan sik we de go bifo . Dis min se in ifekt dεm de inkrεs sכmtεm as tεm - כltεm ova ia, sכmtεm ivin fכ dikεd. Sɔm pipul dɛn nɔ kin gɛt ɛni sayn fɔs, so dɛn nɔ kin ivin no se dɛn gɛt wan pan dɛn sik ya fɔ lɔng lɔng tɛm. Sɔm pipul dɛn nɔr kin ɛva gɛt ɛni sayn ɔr prɔblɛm atɔl.

Bikɔs bɔku difrɛn tin dɛn de we yu kin gɛt, i go fayn fɔ aks yu yay dɔktɔ bɔt wetin fɔ ɛkspɛkt. Dɛn kin tɛl yu wetin go rili impɔtant to yu.

Aw lɔŋ di kɔnia distrofi kin las?

Kɔnia distrofi na tin dɛn we kin apin we pɔsin de liv in layf . Yu bɔn wit dɛn. di kכnia transplant kin "kכl" dεn kכndyushכn dεm ya, bכt dat nכto garanti. Bɔrku pipul dɛm wae gɛt kɔnia transplant go dɔn gɛt dis sik na di kɔnia we dɛn transplant. If dat apin, i kin nid fɔ gɛt mɔ tritmɛnt – ivin sɛkɔn kɔnia transplant.

Wetin na di lukin-grɔn fɔ dis sityueshɔn?

Bɔrku tɛm, kɔnia distrofi kin mek yu nɔr de si sɔm kayn we , bɔt i nɔ kin izi fɔ mek yu nɔ de si fayn fayn wan te yu blaynd ɔltin (na stet we yu nɔ kin ivin si layt).

If yu gɛt kɔnia transplant, yu go gɛt di sem prɔblɛm dɛn we ɔda pipul dɛn we gɛt transplant kin gɛt. Yu go nid fɔ tek di mɛrɛsin dɛn we de mek yu bɔdi nɔ gɛt bɛtɛ wɛlbɔdi fɔ di res ɔf yu layf fɔ mek yu imyun sistɛm nɔ atak di tisu we dɛn transplant. Dɔn bak, ivin wit di tritmɛnt dɛn we de mek pɔsin nɔ ebul fɔ fɛt di sik, i kin mek pɔsin nɔ gri fɔ tek am.

Bikɔs bɔku tin dɛn de we kin afɛkt aw yu de si tin, di bɛst pɔsin fɔ aks bɔt aw yu de si yu sik na yu yay dɔktɔ. Dɛn kin gi yu infɔmeshɔn we gɛt fɔ du wit yu patikyula tin we de apin to yu.

Yu tink se dɛn kin avɔyd di kɔnia distrofi?

Kɔnia distrofi na jɛnɛtik kɔndishɔn, we min se nɔ we nɔ de fɔ mek i nɔ apin ɔ fɔ ridyus di risk fɔ gɛt am.

If a gɛt kɔnia distrofi, aw a go kia fɔ misɛf?

If yu gɛt kɔnia distrofi, yu fɔ go to yu yay dɔktɔ ɔltɛm, lɛk aw dɛn se. Dɛn kin wach yu sik, luk fɔ chenj na yu yay tisu, ɛn ɛni sayn wae yu de gɛt. Dɛn kin ajɔst ɛn ɔpdet yu tritmɛnt plan bak fɔ mek i wok fayn fɔ lɔng tɛm.

If yu ay spɛshal dɔktɔ gi yu mɛrɛsin fɔ yu yay, yu fɔ yuz am jɔs lɛk aw dɛn tɛl yu . Mɛrɛsin kin ɛp fɔ stɔp di sayn dɛm fɔ dɛn kayn tin ya ɔr slo fɔ chenj ɔr pwɛl hat.

Ɛspɛshali if yu dɔn gɛt ɛni kayn kɔnia transplant, i rili impɔtant fɔ tek yu mɛrɛsin dɛn jɔs lɛk aw dɛn tɛl yu fɔ tek. If yu du dat, i go ɛp fɔ mek shɔ se yu bɔdi nɔ rijek di tisu we dɛn transplant. Dis kin ɛp fɔ mek yu nɔ gɛt siriɔs prɔblɛm ɛn ivin fɔ mek yu nɔ si fayn fɔ ɔltɛm.

Ustɛm a fɔ go to mi dɔktɔ we de mɛn mi yay?

Yu go gɛt fɔl-ɔp visit ɔltɛm fɔ di tɛm we dɛn dɔn plan fɔ du am.Yu fɔ go to yu ay spɛshal pɔsin fɔ dis. Dɔn bak, if yu notis ɛni sayn ɔ chenj na yu yay, ɔ if wan tritmɛnt de kɔz sayd ɛfɛkt ɔ i tan lɛk se i nɔ de wok bɛtɛ, yu fɔ tɔk to dɛn bɔt am. Dɛn go tray fɔ ɛp yu fɔ fɛn we fɔ sɔlv di prɔblɛm dɛn we yu de gɛt.

Us kwɛstyɔn dɛn a fɔ aks mi dɔktɔ we de mɛn mi yay?

Yu kin aks yu dɔktɔ we de mɛn yu yay dɛn kwɛstyɔn ya:

• Us kayn kɔnia distrofi a gɛt?
• Us tritmɛnt(dɛn) yu kin advays?
• Ɛni sayn de wae kin mek yu nid fɔ go to dɔktɔ kwik kwik wan?
• Wetin na di lɔng tɛm lukin-grɔn fɔ mi kɔndishɔn?
• Ɛnitin de we a go du fɔ mek a tink gud wan?

Fɔ dɔn, wetin fɔ mɛmba

Kɔnia distrofi na ay sik wae kin kam fɔ no bɔrku tɛm wae yu yɔŋ . If yu de fil bad fɔ tray fɔ ɔndastand dɛn sik ya, nɔto yu wangren de. I pas twɛnti difrɛn kayn kɔnia distrofi. Di tin dɛn we dɛn sik ya kin du kin difrɛn bak.

Bɔt yu nɔr nid fɔ tray fɔ ɔndastand ɔr de manej kɔnia distrofi fɔ yusɛf. Yu yay dɔktɔ kin ɛp yu fɔ ɔndastand yu patikyula sik, di tin dɛn we i kin du, ɛn aw fɔ trit am. Ɛn, wit bɔku tritmɛnt opshɔn dɛm, yu gɛt bɛtɛ chans fɔ kɔntrol yu sik ɛn fɔ mek i nɔr gɛt bɛtɛ impak pan yu layf. Nɔ fred, kɔntinyu fɔ strɔng, ɛn fala yu dɔktɔ in advays.

` Kכnia Distrofi, kכnia na di yay, jεnεtik ay sik, blכr vishכn, ay tritmεnt, kכnia transplant, ay hεlth