Na nɔmal tin fɔ fil smɔl frayd ɛn fred we yu de kam fɔ bigin tritmɛnt fɔ kansa. Bɔt we yu no gud gud wan bɔt di mɛrɛsin we yu de tek ɛn aw i de afɛkt yu bɔdi, da fred de kin ridyus bad bad wan. Tide wi de tɔk bɔt wan mɛrɛsin we dɛn kɔl Dacarbazine, we dɛn kin yuz fɔ mɛn dis kayn kansa. Lɛ wi tɔk bɔt dis simpul we so dat yu go ɔndastand.
Us kayn mɛrɛsin na Dacarbazine?
Fɔ tɔk am simpul wan, dacarbazine na wan kayn mɛrɛsin we dɛn kin yuz fɔ mɛn pipul dɛn we gɛt kemotɛrapi . Kimotɛrapi na wan kayn pawaful mɛrɛsin we dɛn kin gi fɔ stɔp di kansa sɛl dɛn fɔ gro ɔ fɔ kil dɛn.
Dɛn kin yuz dis mɛrɛsin mɔ fɔ mɛn:
- Fɔ kansa na di skin
- We dɛn put am togɛda wit ɔda mɛrɛsin dɛn fɔ trit di sik we dɛn kɔl Hodgkin
Dɛn nɔ de gi yu dis mɛrɛsin na os. Na dɔktɔ ɔ nɔs we dɛn dɔn tren spɛshal fɔ gi am na ɔspitul ɔ klinik kin gi am. Dɛn kin gi di mɛrɛsin insay di bɔdi bay we dɛn injekt am na wan vein ɔ bay we dɛn put am insay wan vein, lɛk salin .
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu bigin tritmɛnt
I rili impɔtant fɔ mek yu dɔktɔ no gud gud wan bɔt yu wɛlbɔdi biznɛs bifo yu bigin dis tritmɛnt. So if yu gɛt ɛni wan pan dɛn tin ya, mek shɔ se yu tɛl yu dɔktɔ .
| Situeshɔn we yu nid fɔ ripɔt | Wetin mek dat impɔtant? |
|---|---|
| Infεkshכn dεm we de naw (e.g., vayral infεkshכn dεm lεk chikinpoks, hεpi) . | Bikɔs dis mɛrɛsin de ridyus di bɔdi in immunity, di infɛkshɔn dɛn we dɔn de kin wɔs. |
| Kidni ɔ liva sik | Bikɔs dɛn ɔgan ya de involv fɔ pul drɔgs na di bɔdi, i impɔtant fɔ no aw dɛn de wok. |
| Kɔndishɔn dɛn lɛk we di rɛd blɔd sɛl dɛn nɔ bɔku, di wayt blɔd sɛl dɛn, ɔ di pletlɛt dɛn | Dacarbazine kin ridyus di nɔmba fɔ dɛn sɛl ya mɔ, so i impɔtant fɔ no bɔt di tin we de apin naw. |
| If yu jɔs dɔn gɛt redyushɔn tɛrapi | Bikɔs ɔl tu di raytin tɛrapi ɛn di kemotɛrapi kin afɛkt di bɔdi, di dɔktɔ fɔ no bɔt dis. |
| If yu gɛt alɛji to dis mɛrɛsin ɔ ɔda mɛrɛsin ɔ it | Dis rili impɔtant fɔ mek yu nɔ gɛt siriɔs alɛji. |
| If yu gɛt bɛlɛ ɔ yu de tray fɔ gɛt bɛlɛ | Dis rili impɔtant. Dis mɛrɛsin kin ambɔg di pikin we de na in bɛlɛ bad bad wan. |
| If yu na mama we de gi pikin in bɛlɛ | Yu fɔ avɔyd fɔ gi pikin in mama in bɛlɛ we yu de tek tritmɛnt, bikɔs di mɛrɛsin kin pas na di mama in milk ɛn i kin ambɔg di pikin. |
Tin dɛn we wi fɔ pe atɛnshɔn mɔ to we wi de tek dis mɛrɛsin:
Yu nid fɔ tek kia smɔl ɛkstra pan yu bɔdi ɔl di tɛm we yu de trit yu.
Dɛn kin du blɔd tɛst ɔltɛm
We yu de tek dis mɛrɛsin, yu dɔktɔ go tɛl yu fɔ du blɔd tɛst ɔltɛm . Dɛn tin ya na fɔ wach aw di mɛrɛsin de afɛkt yu bɔdi ɛn yu blɔd sɛl dɛn. Nɔ skip dɛn tɛst ya.
Diskɔmfɔt
Na nɔmal tin fɔ mek yu fil fayn ɛn yu taya we yu de du kemotɛrapi. Dis na bikɔs dɛn mɛrɛsin ya kin afɛkt ɔl tu di kansa sɛl dɛn ɛn di wɛlbɔdi sɛl dɛn te to sɔm mak. So, nɔ stɔp fɔ trit yu jɔs bikɔs yu nɔ de fil fayn. I impɔtant fɔ dɔn di tritmɛnt saykl we dɛn dɔn tɛl yu pas yu dɔktɔ tɛl yu fɔ stɔp .
Tek tɛm wit infɛkshɔn.
Dis mɛrɛsin kin mek di wayt blɔd sɛl dɛn na di bɔdi we de fɛt sik nɔ bɔku, ɛn dis kin mek pɔsin gɛt infɛkshɔn mɔ ɛn mɔ .
If yu gɛt sɔm sayn dɛn lɛk fiva, kol, trot we de at, kɔf, ɔ nos we de rɔn, nɔ fɔ mɛn yusɛf ɛn kɔl yu dɔktɔ wantɛm wantɛm.. Insay dis tɛm, nɔ fɔ go na say dɛn we sik pipul dɛn de ɛn ples dɛn we pipul dɛn kin bɔku as yu ebul.
Blɔd ɛn brus
Di nɔmba fɔ di pletlɛt dɛn, we de ɛp di blɔd fɔ klɔt, kin go dɔŋ. Dis kin mek yu gɛt mɔ blɔd ɛn brus . Tɛl yu dɔktɔ if yu notis ɛni blɔd we nɔ kɔmɔn, lɛk fɔ brus we yu nɔ ɛksplen, smɔl smɔl rɛd spat dɛn na yu skin, blɔd na yu stɔl, ɔ blɔd na yu urine.
Nɔ gɛt bɛlɛ!
Di tin we impɔtant pas ɔl na fɔ avɔyd fɔ gɛt bɛlɛ ɔltogɛda we yu de du dis tritmɛnt ɛn afta dis tritmɛnt fɔ as lɔng as yu dɔktɔ tɛl yu fɔ du am. Dis mɛrɛsin kin rili ambɔg di pikin we nɔ bɔn yet. Dɔn bak, mama dɛn we de gi pikin in bɛlɛ fɔ avɔyd fɔ gi dɛn pikin in bɛlɛ we dɛn de tek dis tritmɛnt. If yu gɛt ɛni kwɛstyɔn bɔt dis, tɔk to yu dɔktɔ opin wan.
Wetin na di bad tin dɛn we kin apin to pɔsin?
Lɛk ɛni mɛrɛsin, dacarbazine kin mek yu gɛt sayd ɛfɛkt. Bɔt, nɔto ɔlman kin gɛt dɛn. Di tebul we de dɔŋ ya de sho klia wan bɔt dɛn tin ya.
| Posisibul sayd effekt dɛm fɔ Dacarbazine | |
|---|---|
| 🚨 Tin dɛm fɔ ripɔt to yu dɔktɔ wantɛm wantɛm | |
| Alɛji Riakshɔn dɛn | Skin rash, it, swel na di lip/tɔng/fes, i nɔ izi fɔ blo. |
| Di sayn dɛn we de sho se pɔsin gɛt di sik | Fiva, kol, kɔf, trot we de at, pen we yu de pis. |
| Di pletlɛt dɛn we nɔ de bɔku ɔ di sayn dɛn we pɔsin kin gɛt we i de blɔd | Brus we nɔ ɛksplen na di bɔdi, rɛd, fayn fayn spat dɛn na di skin, blak stɔl, ɛn blɔd na di urine. |
| Lɔw rɛd blɔd sɛl (anemia) . | Fɔ fil taya we nɔ kɔmɔn, we nɔ gɛt layf, we nɔ gɛt bɛtɛ trɛnk, we gɛt blu yay. |
| Ɔda siriɔs sayn dɛn | I nɔ izi fɔ blo, di mɔsul dɛn de pen, pen usay dɛn injɛkt di mɛrɛsin, vɔmit, yu yay ɔ yu skin yɔlɔ, chenj na di urine we yu de mek. |
| 🙂 Tin dɛm we kɔmɔn, bɔt dɛn fɔ ripɔt to dɔktɔ if dɛn kɔntinyu | |
| Prɔblɛm dɛn we de na di dijestiv sistɛm | Nɔs, bɛlɛ at, dayarɛa, nɔr kin want fɔ it. |
| Ɔda smɔl smɔl tin dɛn we kin apin | Di ia we de lɔs, di skin kin fil we di san de shayn. |
If yu gɛt ɛni ɔda kayn sik we nɔ kɔmɔn we dɛn nɔ tɔk bɔt na dis list, duya tɛl yu dɔktɔ bɔt dɛn bak.
Wetin a go du if a mis wan doz ɛn tek bɔku mɛrɛsin?
I rili impɔtant fɔ tek yu kemotɛrapi mɛrɛsin di de we dɛn dɔn sɛtul ɛn di tɛm we dɛn dɔn sɛtul. If yu nɔ du dat, dat kin afɛkt di we aw di tritmɛnt go wok fayn. If yu nɔ ebul fɔ go di de we yu dɔn sɛtul, kɔl yu dɔktɔ wantɛm wantɛm .
Bikɔs dɛn nɔ kin yuz dis mɛrɛsin na os, di risk fɔ mek pɔsin tek am pasmak nɔ kin bɔku. Bɔt if yu tink se yu dɔn gɛt am ɛni we, yu fɔ kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta wantɛm wantɛm na di Kɔlɔmbɔ Nashɔnal Ospital , ɔ go na di Imejɛnsi Tritmɛnt Yunit (ETU) na di ɔspitul we de nia yu.
Mɛsej we dɛn kin kɛr go na os
- Dacarbazine na pawaful mɛrɛsin we de fɛt kansa we pipul dɛn we gɛt spɛshal trenin na ɔspitul kin gi am insay dɛn bɛlɛ.
- Bifo yu bigin fɔ trit yu, tɛl yu dɔktɔ bɔt ɔl yu mɛrɛsin, mɛrɛsin dɛn we yu de tek, ɛn alɛji.
- Ɔltɛm, de wach fɔ si sayn dɛm lɛk fiva, blɔd we nɔ kɔmɔn, ɛn brus. If yu notis ɛni wan pan dɛn tin ya, go to dɔktɔ wantɛm wantɛm.
- Nɔ gɛt bɛlɛ ɛn gi pikin in bɛlɛ ɔltogɛda we yu de trit yu.
- Pan ɔl we i nɔmal fɔ mek yu nɔ fil fayn, tɛl yu dɔktɔ bɔt ɛni bad bad tin we kin apin to yu ɔ we kin kɔntinyu fɔ apin.
- Fɔ fala di dɔktɔ in instrɔkshɔn dɛn gud gud wan rili impɔtant fɔ mek di tritmɛnt go bifo.
👩🏽 ⚕️ Ɔda kwɛstyɔn dɛn (FAQ dɛn)
💬 Wetin dɛn kin yuz Dacarbazine (DTIC-Dome) fɔ?
Dis nɔto ɔdinari pil! Dis na wan pawaful kemotɛrapi (Alkylating agent) drɔg we dɛn kin injɛkt dairekt insay pɔsin in vein (IV Injection) na kansa ɔspitul fɔ pwɛl di bad bad ‘Hodgkin’s Lymphoma’ ɛn fɔ mek i skata bad bad wan pan di skin kansa (Metastatic Melanoma)!
💬 Aw dis kεmikכl vaysin (Dacarbazine / Chemo) de dכn kכmplit di kεnsar sεl dεm we i go insay wi bכdi?
fכ mek di kεnsar sεl divayd/riprodyuz, i nid fכ mek nyu ‘DNA’. dis dכg de go insay wi bכdi, εn di liva de aktibכt sכm pan am (Active metabolite - MTIC). afta dat i de go dayrekt insay di kεnsar sεl dεm, i de lכp rawnd di chen we de mek di DNA (GC bays pe) εn i de lכk/lכk am (Alkylation / Cross-linking). we dεn hit/skata di DNA, di kεnsar sεl de bכku εn day rayt de lεk se dεn shot am.
💬 Kansa Deaths Wetin na di risk wae de denja pas ɔl (Black Box Warnings) wae di pɔrsin kin gɛt wae dɛn gi am dis vaysin?
di denja we de kil di sikman na dat dis de mek di mכro we de fכm blɔd pwεl 100% (Bone Marrow Suppression)! We di blɔd sɛl dɛn lɔs, ivin smɔl kol kin mek yu gɛt nyumonia/vomit blɔd ɛn di pɔsin kin day. di ɔda big denja na dat dis kin mek di blɔd vesel dɛn na di liva kin blok (Hepatic Necrosis / VOD) ɛn di liva kin rɔtin. Dɔn bak, vɔmit/nɔs we yu nɔ go ebul fɔ bia go mɔs apin di de we dɛn gi dis injɛkshɔn.
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