We wi kɔt ɔ wund ɛnisay na wi bɔdi, i rili impɔtant fɔ mek blɔd nɔ kɔmɔt . Na wan tin we de mek wi bɔdi ebul fɔ protɛkt wisɛf. Bɔt, wetin kin apin if blɔd klɔt fɔm insay di blɔd vesel dɛn we de insay di bɔdi fɔ natin? Dat kin denja smɔl. Tide wi go tɔk bɔt dis kayn sik we pɔsin kin gɛt frɔm in mama ɛn papa we kin mek di blɔd klɔt we i nɔ nid. Dat na Factor V Leiden trombofilia .
Fɔ tɔk am simpul wan, wetin na Factor V Leiden?
Factor V Leiden thrombophilia na wan kכndyushכn we de kכz fכ wan jεnεtik mכtεshכn we yu gεt frכm we yu bכn . Dis kin mek yu blɔd kin klɔt bad bad wan pas aw i kin klɔt. Dɛn kin kɔl di nem “factor five Leiden.” Di V tinap fɔ di Roman nɔmba fayv.
Nɔto ɔlman wae gɛt dis sik go gɛt blɔd klɔt. Bɔt yu de pan ay risk fɔ gɛt blɔd klot we yu kɔmpia am to pɔsin we nɔ gɛt dis jɛnɛtik chenj. Dis kin mek yu gɛt tu men tin dɛn we de mek yu sɔfa:
- Dip vein thrombosis ( DVT ): Dis na we blɔd klɔt de fɔm insay wan blɔd vesel we de dip insay di bɔdi. Bɔku tɛm, dɛn tin ya kin apin na di vein dɛn na di leg ɔ an. Bɔt sɔntɛnde dɛn kin fɔm bak na di veins na di liva , kidni , bren, ɔ yay.
- Pulmonary embolism (PE): Dis kin denja smɔl. Wetin kin apin ya na dat wan blɔd we dɔn fɔm kin brok, travul wit di blɔd, ɛn stɔp na di lɔng dɛn .
De impɔtant tin na dat yu nɔr nid fɔ panik wans yu dɔn no se yu gɛt dis sik. Nayn pan tɛn pipul dɛm (90%) wae gɛt dis sik nɔr kin ɛva gɛt abnɔmal blɔd klɔt. Bɔt i impɔtant fɔ no bɔt di prɔblɛm dɛn we kin apin.
Wetin na de sayn dɛm wae kin no dis sik?
Infakt, no sayn nɔ de we gɛt fɔ du wit dis jenɛtik mutation. Yu kin liv yu wan ol layf we yu nɔ no. Bɔt if blɔd klɔt, yu go bigin fɔ gɛt sɔm sayn dɛn.
I rili impɔtant: If yu gɛt ɛni wan pan dɛn tin ya we de sho se yu gɛt DVT ɔ PE, go na ɔspitul in Imejɛnsi Dipatmɛnt (ETU) ɔ kɔl ambulans wantɛm wantɛm . Dis nɔto sɔntin we wi fɔ delay.
| Di say we di blɔd de klɔt | Sɔm sayn dɛn we kin apin |
|---|---|
| Dip vein trombosis (DVT) . |
|
| Wan blɔd we de klɔt na di lɔng (PE) . |
|
Wetin mek dis de apin? Wetin na di rizin fɔ dis?
Factor V Leiden de kכz bay wan jεnεtik mכtεshכn. Lɛ wi ɛksplen dis smɔl mɔ simpul wan.
Bɔku kayn prɔtin de we de ɛp wi blɔd fɔ klɔt. dεn kכl dεn tin ya ‘coagulation factors’. "Koaguleshכn fכktכ V" na wan pan dεn kayn kכl protin dεm ya. wi bכdi de instrכkt fכ mek dis protin bay wan jin we dεn kכl `F5`.
nכmal wan, wi כl de bכn wit tu hεlty kכpi dεm fכ dis `F5` jin. כltu, pכsin we gεt Factor V Leiden kכndishכn gεt wan כ tu kכpi dεm fכ dis `F5` jin we nכ de fכm. Dis jin we nɔ fayn na wan grup we de du risach na di siti we nem `Leiden` na di Netherlands bin fɔs fɛn am. Na dat mek i gɛt in nem.
sכm chenj de insay di strכkchכ fכ di Faktor V protin we di bכdi de prodyuz bikoz fכ di instrכkshכn dεm we dεn gεt frכm di dεfektiv `F5` jin. fכ dis sכm chenj, כda protin dεm we dεn kכl `protein C` εn `protein S`, we de kכntro di bכdi we de kכlכt, dat na fכ stכp di bכdi fכ kכlכt we nכ nid, nכ kin kכntro dis כltεr Factor V protin. I tan lɛk motoka we nɔ gɛt brek. So, blɔd kin bigin fɔ klɔt ivin di tɛm we i nɔ nid.
Dis na sɔntin we kɔmɔt frɔm jɛnɛreshɔn?
Yɛs. Yu kin gɛt dis frɔm yu mama, yu papa, ɔ ɔl tu. i de inhεrit insay wan ``autosomal dominant`` patεn. Dis min se yu kin gɛt dis jin we nɔ fayn frɔm yu mama ɔ yu papa.
- כl di pipul dεm (hεterozaygכs) kin gεt wan kכpi nכmכ fכ dis jin we nכ de wok fayn (frכm mama כ papa).
- na sכm tεm we pכsin (homozygous) kin gεt כl tu di kכpi dεm fכ dis difεktiv jin (frכm mama εn papa). Dɛn pipul ya kin gɛt bɔku prɔblɛm fɔ mek dɛn blɔd klɔt.
Us tin dɛn kin mek di blɔd klɔt?
If yu gɛt Factor V Leiden, dɛn tin ya kin mek yu gɛt mɔ blɔd klɔt. So i impɔtant fɔ tɔk bɔt dis wit yu dɔktɔ.
| Risk factor | Tɔk bɔt |
|---|---|
| Influɛns we di jɛnɛtiks gɛt | inhεrit tu kכpi dεm fכ di fכs F5 jin (homozygous). |
| Famili istri | Yu klos famili mɛmba dɛn dɔn gɛt DVT ɔ PE. |
| Ɔda tin dɛn we kin apin to pɔsin we sik | Fɔ gɛt ɔda mɛrɛsin dɛn we kin afɛkt di we aw blɔd kin klɔt. |
| Ɔpreshɔn | Di risk kin bɔku fɔ sɔm tɛm afta dɛn dɔn du big ɔpreshɔn. |
| We uman gɛt bɛlɛ | di risk kin bכku we uman bεlε εn afta dεn bכn pikin. |
| Ɔmon tɛrapi | Fɔ tek bɔn kɔntrol pils ɔ ɔda ɔmon tritmɛnt dɛn we gɛt di ɔmon we dɛn kɔl ɛstrojen. |
| Di we aw pɔsin de liv in layf | Smok, fat, ɛn sidɔm na di sem pozishɔn fɔ tu lɔng. |
Aw dɔktɔ dɛn kin no bɔt dis sik? Wetin na di tritmɛnt dɛn?
If yu gɛt histri fɔ DVT ɔ PE, mɔ we yu yɔŋ, ɔ if pɔsin na yu famili gɛt histri fɔ dis sik, yu dɔktɔ kin sɔprayz se Factor V Leiden.
Dɛn kin du spɛshal blɔd tɛst (inklud di jenɛtik tɛst) fɔ no dis. Dis kin mek yu no klia wan if yu gɛt dis jin we nɔ fayn, ɛn if na so i gɛt, if yu gɛt wan ɔ tu kɔpi pan am.
Di we aw dɛn kin trit am
Bikɔs dis na tin we kin apin to pɔsin in jɛnɛtiks fɔ ɔl in layf, no tritmɛnt nɔ de fɔ chenj di jin. Bifo dat, di tritmɛnt dɛn kin wok fɔ sɔlv di blɔd we dɔn de ɛn fɔ ridyus di risk fɔ mek di blɔd klɔt tumara bambay. Fɔ du dis, yu dɔktɔ kin tɛl yu fɔ du dɛn tin ya:
- Antikoagulant mεdikeshכn: dεn kכl dεm bak ``blood thinners.'' dεn mεdikeshכn dεm ya de sכlv di bכdi kכlכt εn mek nyu kכlכt nכ fכm. Yu dɔktɔ go disayd aw lɔng yu nid fɔ tek dɛn mɛrɛsin ya bay di risk we yu gɛt.
- Kɔmpreshɔn stɔking: Dɛn tin ya kin ɛp fɔ mek di blɔd go fayn fayn wan na di leg dɛn ɛn i kin mek di blɔd nɔ klɔt.
- Vena cava filta: Dis na smɔl tin we tan lɛk filta we dɛn kin put insay wan big vein na di bɔdi fɔ mek di blɔd we kin kam na di leg nɔ go travul go na di lɔng dɛn.
- Ɔpreshɔn: Sɔntɛnde, dɛn kin gɛt ɔpreshɔn fɔ pul di blɔd we dɔn klɔt.
If yu gɛt dis sik, yu fɔ rili tɔk to yu dɔktɔ bifo yu yuz bɔn kɔntrol, plan fɔ gɛt bɛlɛ, ɔ bigin ɛni ɔmon tritmɛnt.
Aw fɔ liv wɛl wit Factor V Leiden?
Fɔ bɔrku pipul dɛm wae gɛt dis sik, nɔr kin afɛkt di layf wae dɛn kin liv. Ivin if blɔd klɔt, tritmɛnt kwik kin mek yu nɔ gɛt siriɔs prɔblɛm. So nɔ panik. Bɔt, i rili impɔtant fɔ tek kia ɔf di we aw yu de liv yu layf.
- Nɔ smok kpatakpata.
- Nɔ sidɔm na di sem pozishɔn fɔ tu lɔng. Ɛspɛshali we yu de flay fɔ lɔng tɛm, grap ɛn waka rawnd ɛn strɛch yu leg dɛn wan tɛm insay awa.
- Mek yu gɛt wɛlbɔdi bɔdi wet.
- Nɔ yuz ɔmon tritmɛnt we gɛt ɛstrojen if yu dɔktɔ nɔ advays yu.
Na nɔmal tin fɔ fil frayd ɛn wɔri we yu kam fɔ no se yu gɛt Factor V Leiden thrombophilia. Bɔt mɛmba se bɔku pan di pipul dɛn we gɛt dis sik kin liv nɔmal layf ɛn nɔ gɛt ɛni prɔblɛm. De tin wae impɔtant pas ɔl na fɔ no bɔt yu sik ɛn fala yu dɔktɔ in advays.
Mɛsej we dɛn kin kɛr go na os
- Factor V Leiden thrombophilia na wan jεnεtik kכndyushכn we de pas dכn tru jεnereshכn. Dis kin mek di blɔd klɔt mɔ ɛn mɔ.
- Nɔto ɔlman wae gɛt dis sik kin gɛt blɔd klɔt. Nayn pan tɛn pipul dɛn nɔ go ɛva gɛt prɔblɛm.
- If yu gɛt sɔm sayn dɛn fɔ DVT ɔ PE, lɛk fɔ swel yu leg, fɔ rɛd, fɔ pen na yu chɛst, ɛn fɔ mek yu nɔ ebul fɔ blo, go na ɔspitul in Imejɛnsi Dipatmɛnt (ETU) wantɛm wantɛm.
- If dɛn no dis sik, tritmɛnt lɛk tin dɛn we de mek blɔd tan kin kɔntrol di we aw blɔd de klɔt.
- Ɔltɛm go to yu dɔktɔ bifo yu bigin ɛni ɔmon tɛrapi ɔ bɔn kɔntrol we ɛn bifo yu gɛt bɛlɛ.
- I rili impɔtant fɔ fala wɛlbɔdi layf ɛn avɔyd tin dɛn we kin mek yu gɛt prɔblɛm.
Factor V Leiden, blɔd we de klɔt, DVT, Pulmonary Embolism, trombophilia, jɛnɛtik sik, blɔd we de klɔt na blɔd vesel, Sri Lanka
💬 Comments (0)
No kɔmɛnt nɔ de yet. Ad yu kɔmɛnt ya fɔ di fɔs tɛm.
Ad yu kɔmɛnt