Yu pikin in chɛst kin tan lɛk se i ful-ɔp ɛn i tan lɛk se in jaw big? I kin bi Chrub rilijɔn. Lɛ wi tɔk bɔt am!

Yu kin wɔri smɔl se yu smɔl pikin in fes dɔn chenj smɔl, wit dɛn chɛst we tan lɛk se dɛn dɔn ful-ɔp. Ɔ di dɔktɔ dɔn tɛl yu bɔt wan chenj na dɛn chin? Wi kɔl dis kɔndishɔn (Chrubism) . Di nem kin tan lɛk se i strenj smɔl, bɔt lɛ wi kip am simpul. Dis na wan sik wae nɔr kin bɔrku, bɔt e impɔtant fɔ no bɔt am.

Wetin na Chrubizm?

Fɔ tɔk am simpul wan, Chɛrɔb na tin we nɔ kin apin so ɔltɛm. I kin apin we abnɔmal tisu de gro na yu pikin in jawbon insted ɔf wɛlbɔdi bon tisu. Dis abnɔmal tisu nɔto kansa ɛn bɔku tɛm i nɔ kin gɛt pen. Bɔt i kin mek di pikin in jaw wayd na in tu say ɛn dɛn chɛst kin luk rawnd ɛn blo . Sɔm pikin dɛn kin lɔs dɛn tit ɔ dɛn kin gɛt tit we nɔ kin gro ɔltɛm. Chɛrɔb nɔ kin afɛkt ɔda bon dɛn na di bɔdi, na di jawbon nɔmɔ .

Dɛn sayn ya nɔ kin bigin fɔ sho wantɛm wantɛm afta dɛn bɔn am. Dɛn kin apia bitwin 2 ɛn 7. De kayn sik kin difrɛn frɔm wan pɔrsin to ɔda pɔrsin. Sɔm pikin dɛn nɔ kin gɛt ɛni sayn atɔl, ɔ di sayn dɛn kin rili klia ɛn dɛn nɔ kin notis am. Bɔt we i rili bad, i nɔ kin izi fɔ di pikin fɔ tɔk, fɔ swɛla, ɔ ivin fɔ blo.

Di bɛst pat na dat, bɔku tɛm, chɛrɔb kin sɔlv insɛf bay we i big we dɛn nɔ gɛt tritmɛnt. Dɔktɔ dɛn kin de wach dis sik ɔltɛm ɛn dɛn kin jɔs tɛl am fɔ trit am if di sik bad bad wan ɔ if i de ambɔg di pikin in kwaliti layf bad bad wan.

Aw kɔmɔn tin fɔ bi Krub?

Chɛrɔb nɔto tin we bɔku pipul dɛn kin gɛt. Risach pipul dɛm nɔr no ɔmɔs pipul dɛm gɛt dis sik, bɔt dɛn dɔn mek sɔm ɛstimat bays pan mɛdikal atikul dɛm wae dɛn dɔn pul. Wan stɔdi we dɛn bin du insay 2019 sho se na 513 pipul dɛn we gɛt Chɛrɔb rilijɔn we dɛn bin dɔn ripɔt na di buk dɛn we dɛn kin rayt bɔt mɛrɛsin. So yu kin si aw i nɔ kin bɔku.

Wetin na di sayn dɛn we de sho se pɔsin gɛt Chɛrɔb?

Dɛn tin ya na di kɔmɔn sayn dɛn we de sho se pɔsin gɛt Chɛrɔb:

• di lכw jaw bon (mandibul) de wayd pas aw dεn bin de εkspεkt.
• di tin dεm we de gro lεk sist na di pikin in jaw εria.
• Raun, puffy cheeks.
• Chenj na di shep fɔ di tit, di tit we nɔ de, ɔ di tit we gɛt impak.

Sɔm pikin dɛn kin gɛt dɛn sik ya bak:

• I tan lɛk se di yay dɛn de kɔmɔt na do ɛn de luk ɔp. di wayt pat pan di yay (sclera) de sho כnda di blak ayris.
• di ekstra tisu na di כp jaw de afekt di yay εn di nεv dεm we de wit am, we de mek i nכ de si fayn כ sכmtεm i nכ de si.
• Mɔt we yu de blo.
• Fɔ snor.
• Obstruktiv slip apnɛa.
• I nɔ izi fɔ tɔk ɔ swɛla.

Wetin na di tin dɛn we de mek pipul dɛn na Chɛrɔb?

כl di kes dεm fכ chεrub (mכr dan 90%) na di mכtεshכn dεm na di jin we dεn kכl `SH3BP2`.

dis `SH3BP2` jin de instrכkt wi bכdi aw fכ mek di `SH3BP2` protin. dis protin de involv insay di prכsεs fכ pul ol bon tisu εn bil nyu bon tisu (bon rimכdelin). di jεnεtik mכtεshכn dεm de mek di bכdi de prodyuz tu mכch pan dis `SH3BP2` protin.

we dis protin de prodyuz pasmak, inflameshn de apin na di jawbone. i de mek bak di sεl dεm we dεn kכl כstioklast . כstioklast na wan kayn sεl we de ple imכtant rol fכ brok di bon tisu dεm we di bכdi nכ nid igen. Bɔt we dɛn sɛl ya bɔku pasmak, dɛn kin bigin fɔ brok di bon tisu dɛn na di jawbon we dɛn nɔ nid am. dis abnכmal bon we de lכs, we dεn kam togεda wit di inflameshn we de kכz fכ di inkrεs pan SH3BP2, de mek di fכmeshכn fכ sist lεk growth dεm na di jawbon. dis growth dεm de gro sכmtεm, na dat de mek di kכntribyushכn simptom dεm fכ di kכndyushכn (Cherubism).

כltu, sכm pikin dεm we gεt Chεrubism nכ gεt di SH3BP2 jin mכtεshכn. If na so i bi, ɔda tin dɛn we kin chenj na di jɛnɛtiks kin mek i apin. Bɔt di wan dɛn we de stɔdi bɔt dis nɔ dɔn no yet ustɛm dɛn chenj dɛn de.

Na (Chrubism) na sɔntin we de kɔmɔt frɔm wan jɛnɛreshɔn to di ɔda wan?

Yɛs, bɔku pikin dɛn kin gɛt di chenj we dɛn kin chenj dɛn jɛnɛtiks we kin mek dɛn bi Chɛrɔb. di kכndishכn de pas dכn insay wan כtosom dכminant patεn fכ inhεrit. Fɔ tɔk am simpul wan, if wan mama ɔ papa gɛt di jenɛtik mutation, di pikin gɛt chans fɔ gɛt am bak.

Bɔt sɔm pikin dɛn kin gɛt dis sik ilɛksɛf nɔbɔdi na di famili nɔ bin dɔn gɛt dis sik bifo. Risach pipul dεm kכl dis ‘de novo mutation’ . Dat min se, nyu jɛnɛtik chenj we kin apin to pɔsin, we nɔ gɛt ɛni famili istri.

So, pan ɔl we bɔku tɛm na Kirub dɛn kin kɔmɔt frɔm dɛn gret gret granpa dɛn, nɔto ɔltɛm i kin bi. Ivin if nɔbɔdi nɔ de na di famili we gɛt dis sik, dɔktɔ dɛn kin tek Chɛrɔb as sɔntin we pɔsin kin no bɔt.

Yu tink se ɔda tin dɛn de we gɛt fɔ du wit di Chɛrɔb rilijɔn?

Insay sɔm pikin dɛn, Chɛrɔb kin apin bak as pat pan ɔda jenɛtik kɔndishɔn. Sɔm pan dɛn tin ya we gɛt fɔ du wit dis na:

• `(Fragile X sindrom)`
• `(Jaffe-Campanacci sindrom)`
• `(Nyurofibromatosis tayp 1)`
• `(Noonan sindrom)`
• `(Ramɔn sindrom)`

insay dεn kayn kes dεm ya, di kכz fכ Chεrubism nכto di SH3BP2 jin mכtεshכn. Bifo dat, ɔda chenj dɛn we de apin na di jɛnɛtiks we gɛt fɔ du wit di sik na dɛn kin mek dɛn gɛt dis sik.

Aw dɔktɔ dɛn kin no se dɛn gɛt Chɛrɔb?

Dɔktɔ dɛn kin fala dɛn tin ya fɔ no if pɔsin gɛt Chɛrɔb:

• Fɔ chɛk in bɔdi: Dis kin min fɔ chɛk di pikin fɔ si if i gɛt sɔm sayn dɛn lɛk in jaw we nɔ kɔmɔn, in tit we nɔ de, ɔ in tit prɔblɛm (Cherubism).
• Ɔda imej tɛst: Dɛn tɛst ya na tɛst lɛk X-ray ɔ CT skan (kɔmpyuta tomografi skan) . Dɛn tin ya kin ɛp fɔ no di kayn we aw di jawbon de fayn fayn wan.
• Ɔda jenɛtik tɛst: Dɛn kin du dɛn tɛst ya fɔ chɛk fɔ si if di jɛnɛtik chenj dɔn chenj.

Dɔktɔ dɛn nid bak fɔ pul ɔda sik dɛn we gɛt di sem kayn sik, lɛk fibrous dysplasia ɔ aneurysmal bone cysts , ɛn fɔ no if Chɛrɔb na pat pan wan jenɛtik sindrom.

Wetin na di tritmɛnt fɔ Chɛrɔb?

Bɔku pikin dɛn we gɛt chɛrɔb nɔ nid ɛni spɛshal tritmɛnt. Bɔku tɛm, di dɔktɔ dɛn we de mɛn pikin dɛn kin tek "wet ɛn si" we. Dat min se dɛn kin wach di sik ɛn si aw i kin bi. Bɔku tɛm, dɛn abnɔmal tisu dɛn ya kin gro te di pikin rich di tɛm we i fɔ bɔn, dɛn kin de di sem fɔ sɔm ia, dɔn dɛn kin bigin fɔ smɔl smɔl smɔl. Di sayn dɛm fɔ chɛrɔb kin dɔn we pɔsin big.

Bɔt if yu pikin gɛt prɔblɛm fɔ it ɔ fɔ blo, di dɔktɔ kin tɛl am fɔ du ɔpreshɔn. Bɔt, dɔktɔ dɛn kin se dɛn fɔ du ɔpreshɔn afta di tisu we nɔ de gro dɔn stɔp. If pɔsin stil gɛt sɔm sayn dɛn ɛn i want fɔ chenj di we aw in fes tan, dɛn kin tink bɔt fɔ du ɔpreshɔn. Rikɔnstrɔktiv ɔpreshɔn kin ɛp fɔ shep pɔsin in fes bak di we aw i lɛk.

Tritmɛnt dɛn we de sɔpɔt pɔsin

Chɛrɔb kin afɛkt bɔku tin dɛn na pikin in layf, mɔ if di sik rili bad. So, di pikin kin nid tritmɛnt we dɛn mek fɔ wetin i nid. Di tritmɛnt we dɛn kin pik kin bi:

• Tit tritmɛnt: Pikin dɛn we gɛt chɛrɔb kin nid fɔ gɛt dɛnt tritmɛnt, lɛk fɔ pul dɛn tut ɔ fɔ put dɛn tut insay tut . we di tin dεm we de gro lεk sist na di jaw bigin fכ shrink, di pikin kin nid bak bres (כtכdכnt) .
• Sɔpɔt we pɔsin de si: If i gɛt siriɔs chɛrɔb, di pikin in yay kin afɛkt. Wan dɔktɔ we de mɛn di pikin kin chɛk aw di pikin de si ɛn fɛn di bɛst sɔlv fɔ wetin i nid.
• Ɛp fɔ tɔk ɛn swɛla: If i nɔ izi fɔ di pikin fɔ tɔk ɔ fɔ swɛla, .Wan dɔktɔ we de mɛn pipul dɛn we de tɔk ɛn langwej (SLP) kin ɛp.
• Saikɔlɔjik sɔpɔt: Chɛrɔb kin afɛkt di we aw pikin de fil bɔt insɛf. I impɔtant fɔ tɔk to yu pikin bɔt aw i de fil ɛn aw dis sik de afɛkt aw i de tink bɔt insɛf. Yu pikin kin bɛnifit if yu tɔk to pɔsin we de stɔdi bɔt pikin dɛn maynd bɔt aw i de fil.

Wetin di wan dɛn we gɛt Chɛrɔb rilijɔn go si?

Bɔku pipul dɛn nɔ go gɛt ɛni sayn fɔ Chɛrɔb we dɛn ol 30. Bay da tɛm de, di nɔmal bon tisu dɔn tek di nɔmal bon tisu in ples.

Na smɔl tɛm nɔmɔ, di sayn dɛn we de sho se di chɛrɔb kin kɔntinyu fɔ de te i big. If dis apin, dɔktɔ go gi yu di advays ɛn sɔpɔt we yu nid.

Yu tink se dɛn go ebul fɔ stɔp Chɛrɔb?

Dɔktɔ nɔr no ɛni we fɔ mek dis sik nɔ kam. If pɔsin na yu famili gɛt Chɛrɔb, i go fayn fɔ mek yu gɛt kɔyl fɔ yu jɛnɛtiks bifo yu gɛt bɛlɛ.

Aw a go kia fɔ mi pikin?

If yu pikin gɛt Chɛrɔb, no bɔt dɛn tin ya:

• Kɔntinyu fɔ kɛr yu pikin go to dɔktɔ we de mɛn pikin dɛn. Di dɔktɔ go tɛl yu aw ɔltɛm yu fɔ kam bak.
• Mek dɛn chɛk yu pikin in yay akɔdin to di schedule we di dɔktɔ tɛl am fɔ du.
• Sɔpɔt di pikin wit di we aw i de fil. Ɛnkɔrej dɛn, tɔk to dɛn.

Ustɛm a fɔ kɔl dɔktɔ?

Kɔl yu dɔktɔ we de mɛn pikin dɛn if yu pikin gɛt ɛni wan pan dɛn tin ya:

• I nɔ kin izi fɔ blo, lɛk fɔ snor ɔ fɔ slip we yu nɔ ebul fɔ blo .
• I nɔ izi fɔ swɛla.
• I nɔ izi fɔ tɔk.
• Prɔblɛm dɛn we pɔsin kin gɛt we i de si.

Aw di nem (Kɛrɔb) kam?

Na Dɔktɔ Wiliam A. Jɔns bin gi di sik in nem insay 1933 . I pik di nem "Cherubism" bikɔs di sayn dɛm fɔ di sik na fɔ mek yu fes tan lɛk pikin, we ful-ɔp ɛn sɔntɛnde in yay dɛn kin tɔn ɔp. I bin biliv se dɛn tin ya tan lɛk di wan dɛn we “chɛrɔb” gɛt, we na wan fayn ɛn enjɛl figa we dɛn kin si na art ɛn difrɛn rilijɔn tradishɔn dɛn. Frɔm da tɛm de, dɛn dɔn de yuz di nem.

I kin mek yu sɔprayz fɔ no se yu pikin gɛt wan sik we nɔ kin apin so ɔltɛm. We i kam pan Chɛrɔb, di sayn dɛn nɔ kin de we dɛn bɔn am, so yu kin wɔri we yu si chenj na yu pikin in fes ɔ we dɔktɔ tɔk bɔt am. Bɔt mɛmba se bɔku pan di kes dɛn we di Chɛrɔb dɛn kin gɛt kin sɔlv fɔ dɛnsɛf bay di tɛm we di pikin dɔn big.If i siriɔs, dɔktɔ dɛn kin trit di tin dɛn we de apin to di sik (Cherubism). If yu gi yu pikin bɔku lɔv ɛn sɔpɔt am pan aw i de fil, dat go ɛp am fɔ gɛt ɔl di kia we i nid fɔ mek i yuz dɛn pikin ɛn yɔŋ tɛm fayn fayn wan.

Mɛsej we dɛn kin kɛr go na os

Chɛrɔb na wan sik we nɔ kin apin so ɔltɛm we kin afɛkt di jawbon. Dis kin mek di pikin in chɛst dɛn kin bɔl ɛn di jaw kin tan lɛk se i wayd. Dis kin bɛtɛ as di pikin de gro. Bɔt if i nɔ izi fɔ dɛn fɔ blo ɔ swɛla, go to dɔktɔ. Di tin we impɔtant pas ɔl na fɔ kɔntinyu fɔ gi yu pikin yu lɔv ɛn sɔpɔt. Di tin we impɔtant pas ɔl na fɔ ɛp yu pikin fɔ gɛt trɛnk we i de fala di advays we dɔktɔ gi yu. Nɔ wɔri, nɔto yu wan de pan dis waka.

` Chεrubism, jεnεtik sik dεm, jawbone, bulging cheeks, pikin dεm sik, dental prכblεm, SH3BP2 jin