Yu dɔktɔ dɔn gi Glasdegib (Daurismo) fɔ yu ɔ sɔmbɔdi na yu famili fɔ wan kansa we dɛn kɔl Acute Myelogenous Leukemia? Na wan rili pawaful drɔg we gɛt kɔmplikɛt nem. So, dis na wan rili simpul ɛn fayn we fɔ tɔk bɔt dis drɔg, aw dɛn de yuz am, ɛn wetin wi nid fɔ tek tɛm mɔ bɔt.
Us kayn mɛrɛsin na Glasdegib?
Fɔ tɔk am simpul wan, Glasdegib na mɛrɛsin we de tɔch di kansa sɛl dɛn ɛn stɔp dɛn fɔ gro. Di kansa sɛl dɛn na wi bɔdi nid spɛshal prɔtin fɔ mek dɛn gro. Wetin dis drɔg de du na fɔ stɔp di wok we dɛn prɔtin dɛn de de du. Dis we ya, we di kansa sɛl dɛn nɔ ebul fɔ gro, wi kin gɛt big ɛp fɔ kɔntrol kansa.
Dɛn kin yuz dis mɛrɛsin mɔ fɔ mɛn wan kayn blɔd kansa we dɛn kɔl acute myelogenous leukemia. Sɔntɛnde, yu dɔktɔ kin gi yu dis mɛrɛsin bak fɔ ɔda sik dɛn. Yu dɔktɔ go ɛksplen dis to yu ditayli.
De tin wae impɔtant pas ɔl fɔ tɛl yu dɔktɔ bifo yu tek dis mɛrɛsin
Bikɔs Glasdegib na mɛrɛsin we rili strɔng, i rili impɔtant fɔ tɛl yu dɔktɔ bɔt ɛni ɔda mɛrɛsin we yu gɛt. If yu gɛt ɛni wan pan di sik dɛn we de dɔŋ ya, tɛl yu dɔktɔ bɔt am bifo yu bigin fɔ tek di mɛrɛsin.
- If yu gɛt at sik.
- If yu bin dɔn gɛt at bit we nɔ de bit ɔltɛm.
- If yu gɛt histri fɔ ɛni sik we gɛt fɔ du wit yu mɔsul.
- If yu gɛt sik na yu kidni.
- If yu gɛt liva sik.
- if di lεvεl fכ di ilektrolayt dεm na di bכdi (e.g. potashכm, magnεsium) tu lכw כ tu hכy.
- If yu dɔn gɛt alɛji fɔ Glasdegib, ɔda mɛrɛsin, it, day, ɔ tin dɛn we de mek yu nɔ pwɛl.
- If yu gɛt bɛlɛ, ɔ yu de plan fɔ gɛt bɛlɛ jisnɔ.
- If yu na mama we de gi pikin in bɛlɛ.
If yu ayd dis infɔmeshɔn frɔm yu dɔktɔ, dat kin put yu wɛlbɔdi pan denja we nɔ nid fɔ de, so nɔ fred fɔ tɔk opin wan bɔt ɔltin.
Aw fɔ yuz di mɛrɛsin kɔrɛkt wan?
I rili impɔtant fɔ tek di mɛrɛsin jɔs lɛk aw di dɔktɔ tɛl yu fɔ tek am, insay di kɔrɛkt doz, di rayt tɛm.
- Swɛla dis tablɛt ɔl wit wan glas wata. Nɔ brok, krɔs, ɔ chew di tablɛt.
- Yu kin tek dis wit it ɔ yu nɔ it am. Bɔt di tin we impɔtant pas ɔl na fɔ tek am di sem we ɛvride.Fɔ ɛgzampul, if yu bigin fɔ tek am afta yu dɔn it, tek am ɛvride afta yu dɔn it. If yu bigin fɔ tek am bifo yu it, tek am ɛvride bifo yu it.
- Nɔ ɛva stɔp fɔ tek mɛrɛsin wantɛm wantɛm if yu dɔktɔ nɔ advays yu.
- If yu de gi pikin dɛn dis mɛrɛsin, tɔk to dɔktɔ we de mɛn pikin dɛn bɔt am ɛn jɔs yuz am akɔdin to in instrɔkshɔn.
- If yu aksidɛntli tek bɔku mɛrɛsin: If yu tink se yu dɔn tek bɔku mɛrɛsin, kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta wantɛm wantɛm na di Kɔlɔmbɔ Nashɔnal Ospital , ɔ go na di Imejɛnsi Tritmɛnt Yunit (ETU) we de nia yu.
Wetin yu kin du if yu mis wan doz?
If yu fɔgɛt fɔ tek wan doz, tek am jɔs lɛk aw yu mɛmba. Bɔt if i nɔ rich 12 awa te yu tek di nɛks doz, skip di doz we yu mis ɛn tek di nɛks doz di tɛm we yu dɔn sɛtul. Nɔ ɛva tek tu dos wan tɛm.
Wetin na di tin dɛn we nɔ fayn fɔ yuz dis mɛrɛsin?
Glasdegib kin intarakt wit ɔda mɛrɛsin, so i impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek.
Nɔ tek dɛn mɛrɛsin ya wit Glasdegib:
- Cisapride we dɛn kɔl Cisapride
- dronedarone we dɛn kɔl dronedarone
- flukonazɔl we dɛn kɔl fluconazole
- pimozayd we dɛn kɔl pimozide
- posakonazɔl we dɛn kɔl
- saquinavir we dɛn kɔl saquinavir
- tioridazin we dɛn kɔl tioridazin
Dɛn mɛrɛsin ya kin intarakt bak wit Glasdegib:
- Antivayrɔs drɔgs fɔ HIV ɔ AIDS
- Sɔm mɛrɛsin fɔ fungal infɛkshɔn (e.g. itraconazole, ketoconazole) .
- Sɔm antibayɔtiks (e.g. klarithromycin) .
- Sɔm mɛrɛsin fɔ mek yu gɛt sik (e.g. carbamazepine, phenytoin) .
- Ɔda mɛrɛsin dɛn we kin mek di at bit nɔ de bit ɔltɛm (lɔng di QT intaval) .
- Tradishonal mɛrɛsin dɛn lɛk Sɛnt Jɔn Wɔt
- Grepfruit jus we dɛn kin mek
Dis list nɔ kɔmplit. So gi yu dɔktɔ wan kɔmplit list fɔ ɔl di mɛrɛsin dɛn, vaytamɛn dɛn, ɛbul mɛrɛsin dɛn, ɛn sɔpɔtmɛnt dɛn we yu de tek. Nɔ fɔgɛt fɔ tɛl dɛn if yu de smok ɔ drink rɔm.
Tin dɛm fɔ tek tɛm mɔ bɔt we yu de tek Glasdegib
- Blɔd tɛst: I fɔ mek yu du blɔd tɛst (blɔd wok) lɛk aw yu dɔktɔ tɛl yu we yu de tek dis mɛrɛsin.
- Bɛlɛ: uman dɛn fɔ avɔyd fɔ gɛt bɛlɛ we dɛn de tek dis mɛrɛsin ɛn fɔ at le 30 dez afta dɛn dɔn stɔp di mɛrɛsin. Man dɛn fɔ avɔyd bak fɔ bɔn pikin we dɛn de tek dis mɛrɛsin ɛn fɔ at le 30 dez afta dɛn dɔn stɔp di mɛrɛsin. Dis mɛrɛsin kin ambɔg di pikin we nɔ bɔn yet bad bad wan.
- Fɔ gi pikin in mama in bɛlɛ: We yu de tek di mɛrɛsin ɛn fɔ at le 30 dez afta yu dɔn stɔp.Nɔ gi di pikin in bɛlɛ.
- Sεm εn blɔd gi: Nɔ gi sperm ɔ blɔd we yu de tek di mɛrɛsin ɛn fɔ at le 30 dez afta yu dɔn stɔp.
- Fɔ bɔn pikin: Dis mɛrɛsin kin afɛkt di we aw yu ebul fɔ bɔn pikin. If yu gɛt ɛnitin fɔ wɔri bɔt dis, tɔk to yu dɔktɔ.
Sayd ɛfɛkt dɛn we kin apin bikɔs ɔf mɛrɛsin
Lɛk ɛni mɛrɛsin, Glasdegib kin gɛt sayd ɛfɛkt. Sɔm dɛn nid fɔ pe atɛnshɔn to dɛn kwik kwik wan, ɛn ɔda wan dɛn kin kɔmɔn.
| Sayd ɛfɛkt we pɔsin kin gɛt | Tɔk bɔt |
|---|---|
| Tin dɛn fɔ ripɔt to yu dɔktɔ ɔ Imejɛnsi Dipatmɛnt (ETU) wantɛm wantɛm | |
| Alɛji we pɔsin kin gɛt | Skin rash, it, swel na di fes, lip ɔ tong. |
| I nɔ izi fɔ blo | I nɔ kin izi fɔ yu fɔ blo. |
| Sayn dɛn we de sho se pɔsin gɛt di sik | Fiva, kol, trot we de at, mɔt we de at. |
| Mɔsul dɛn kin pen | Di pen we yu nɔ ɛksplen, we gɛt siriɔs mɔsul pen. |
| Blɔd we nɔ de kɔmɔt fayn | Blak ɔ blɔd stɔl; fɔ vɔmit sɔntin we tan lɛk kɔfi grɔn; rɛd spat dɛn na di skin; blɔd we de kɔmɔt na yu nos, yu gɔm, ɔ yu yay; di brus we nɔ kɔmɔn na di skin. |
| Di chenj dɛn we de apin na di at rit | Chɛst pen, diziz, at de bit fast ɔr nɔr de bit ɔltɛm, fil lɛk yu nɔr de fil fayn, yu de fɔdɔm. |
| Taya we nɔ kɔmɔn | Fɔ fil pasmak, wik ɔ taya pasmak, we nɔ kɔmɔn. |
| Tɛl yu dɔktɔ if i kɔntinyu fɔ de ɔ i de mɔna yu. | |
| Chenj in teist | Di teist fɔ it kin chenj. |
| Banbɛlɛ | I nɔ izi fɔ pas stɔl. |
| Vɔmit | Fɔ fil lɛk se yu de vɔmit. |
| De swɛl | Di anklɛ, fut, ɔ an dɛn kin swel. |
| Jɛnɛral taya | Fɔ fil se yu taya smɔl. |
If yu gɛt ɛni ɔda kayn sik we nɔ kɔmɔn we dɛn nɔ tɔk bɔt na dis list, duya tɛl yu dɔktɔ bɔt dɛn bak.
Mɛsej we dɛn kin kɛr go na os
- Ɔltɛm tek Glasdegib jɔs lɛk aw yu dɔktɔ tɛl yu fɔ tek, di rayt tɛm, ɛn di rayt doz.
- Bifo yu bigin fɔ tek di mɛrɛsin, tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn, vaytamɛn dɛn, tradishɔnal mɛrɛsin dɛn we yu de tek, ɛn ɛni mɛrɛsin we yu gɛt.
- Nɔ fɔ gɛt bɛlɛ, fɔ gi pikin in bɛlɛ, fɔ gi blɔd, ɛn fɔ gi swɛt we yu de tek dis mɛrɛsin ɛn fɔ 30 dez afta yu dɔn stɔp. Dis kin apin to uman ɛn man.
- If siriɔs sayd ɛfɛkt (e.g., at fɔ blo, blɔd we nɔ kɔmɔn, pen na yu chɛst) apin, go to dɔktɔ wantɛm wantɛm ɔ go to di Imejɛnsi Dipatmɛnt (ETU).
- Dɛn dɔn gi yu dis mɛrɛsin fɔ yu nɔmɔ. Nɔ sheb am wit ɔda pipul dɛn fɔ ɛni rizin.
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