Yu mɔsul dɛn de bit ɔ tayt ɔltɛm? Dis kin bi wan sik wae nɔr kin bɔrku wae dɛn kɔl Isaacs’ Syndrome?

Sɔntɛnde yu kin fil lɛk se yu mɔsul dɛn jɔs de twit, ɔ wantɛm wantɛm yu mɔsul dɛn de twis ɛn tayt? Dɛn sayn ya kin rili kɔmɔn pan big pipul dɛm. Bɔku tɛm, dɛn nɔ kin siriɔs. Bɔt, na smɔl tɛm nɔmɔ, dɛn sayn ya kin bi sayn fɔ wan siriɔs nyurolɔjik kɔndishɔn. Wan pan dɛn kayn tin ya we nɔ kin apin so ɔltɛm we wi go tɔk bɔt tide na di sik we dɛn kɔl Isaacs’ syndrome.

Wetin na di sik we dɛn kɔl Isaacs’ Syndrome? Lɛ wi ɔndastand am simpul wan!

Okay, mek wi si wetin na dis. Isaacs’ syndrome na wan nyuromɔskular disɔda we kin rili, rili rare. wetin kin apin pan dis na dat di nεv dεm na wi bכdi in pεrifεral nεv sεstem kin כva stimulate. Tink bɔt am lɛk we dɛn de on ɛn ɔf ilɛktrik switch ɔltɛm, wi nerv dɛnsɛf kin wok we wi nɔ nid. Dis kin mek di mɔsul dɛn bigin fɔ wok fɔ dɛnsɛf, ɛn wi nɔ kin ebul fɔ kɔntrol dɛn.

Bɔrku tɛm, pɔrsin wae gɛt dis sik kin gɛt mɔsul dɛm wae de spam, kramp, ɛn twitch. sכmtεm dis kin afekt wi כtonom nεv sεstem bak. Dis kin mek tin lɛk wae yu de swet pasmak ɛn yu at kin chenj.

Dɛn kin kɔl dis bak:

• Kɔntinyu fɔ gɛt mɔsul fayba aktiviti sindrom
• Di sik we dɛn kɔl Isaacs-Mertens syndrome
• Nyuromayotonia we de mek pɔsin gɛt sik
• Kwantal skwander sindrom

Aw kɔmɔn tin na dis sik we dɛn kɔl Isaacs’ Syndrome?

Infakt, dis na tin we nɔ kin apin so ɔltɛm. Ivin sayɛnsman dɛn nɔ kin ebul fɔ tɔk klia wan ɔmɔs pipul dɛn gɛt am, bikɔs te naw, na sɔm ɔndrɛd pipul dɛn nɔmɔ dɛn dɔn ripɔt ɔlsay na di wɔl.

Bɔt lɛk aw wi bin dɔn tɔk, di mɔsul dɛn we de kramp ɛn we di mɔsul dɛn kin shek (sɔntɛnde dɛn kin kɔl am fasciculations ) kin rili bɔku pan big pipul dɛn. Bɔku tɛm, dɛn nɔ kin denja. So nɔr frayd fɔ tink se Isaacs’ syndrome na siriɔs nyurolɔjik kɔndishɔn jɔs bikɔs yu gɛt wan. Bɔrku pipul kin gɛt dɛn kayn sik ya fɔ ɔda, simpul rizin.

Udat kin gɛt dis sik we dɛn kɔl Isaacs’ Syndrome?

Bɔrku tɛm, dis sik kin bigin bitwin 15 ɛn 60 ia. Bɔt dɛn dɔn ripɔt dis sik pan yɔŋ pipul dɛm, sɔmtɛm ivin pikin dɛm.

Dis sik kin gɛt fɔ du wit sɔm ɔda mɛrɛsin dɛn. Dis min se pipul dɛm wae gɛt dɛn kayn sik ya kin gɛt dis sik. Na sɔm ɛgzampul dɛn ya:

• Kansa
• Siliak sik we dɛn kin gɛt
• Kronik inflammatory demyelinating polyneuropathy (CIDP) - Dis na sik bak na di nerv.
• Sindrom we nem Guillain-Barré we gɛt di sik
• Di sik we dɛn kɔl Hashimoto
• Lupus we gɛt di sik
• Myasthenia gravis we gɛt di sik
• Nyuropathy we de na di periferik
• Rimatɔyd at at sik
• Taymoma - Dis na kansa we de divεlכp na di taymus gland.
• Vitamin B12 we nɔ de

Wetin na di tin dɛm wae kin mek dis sik wae dɛn kɔl nyuromyotonia?

Tu men rizin dɛn kin de fɔ dis:

1. Acquired: Dis na ɔtoimyun kɔndishɔn. Fɔ tɔk am simpul wan, di imyun sistɛm na wi bɔdi kin bigin fɔ atak wi yon wɛlbɔdi sɛl dɛn lɛk se na fɔrina dɛn we de kam insay wi. כlmost 50% pan di pipul dεm we gεt Isaacs sεndrכm gεt antibodi dεm we de atak di chanεl dεm we de alaw di εlektrolayt potashכm fכ go insay εn kכmכt na wi nεv dεm. dis muvmεnt fכ potashכm de afekt di nεv fכ wok. We dɛn chanɛl ya dɔn pwɛl, di nɛv dɛn kin wok pasmak.

2. Hεriditary kכndishכn: Dis na jεnεtik. Dat min se, na frɔm mama ɛn papa dɛn kin gɛt am to pikin dɛn.

Wetin na di sayn dɛm wae de sho se yu gɛt dis sik we dɛn kɔl Isaacs’ Syndrome?

Dɛn sayn ya kin de ɔlsay na di de ɛn dɛn kin ivin apin we yu de slip. Bɔrku tɛm, di sayn dɛm wae de sho se yu mɔsul dɛn de kramp kin mɔs notis na di an ɛn leg. Bɔt i kin afɛkt ɔda pat dɛn na di bɔdi bak.

Na sɔm pan di men sayn dɛm wae de sho se yu gɛt dis sik:

• Ataxia: Dis min se yu nɔ de balans ɛn yu bɔdi nɔ de wok togɛda we yu de waka ɔ muv. Yu kin swɛla lɛk pɔsin we dɔn chak.
• Taym we i tek fɔ mek di lump lɔs: We di lump tayt, i kin tek lɔng tɛm fɔ mek i kam bak to nɔmal.
• Fɔ swet pasmak (hyperhidrosis): Fɔ swet pasmak fɔ natin.
• Di chenj dɛn we de apin na di at rit: Di at bit kin bit kwik kwik wan ɔ slo .
• Taya ɛn nɔ ebul fɔ slip: Yu kin fil taya ɔltɛm ɛn nɔ kin ebul fɔ slip na nɛt.
• Fɔ rɔl, tayt, bit, ɛn wik: Dɛn tin ya kin bɔku smɔl smɔl as tɛm de go.
• Mayokamia: Dis na filin we di mɔsul dɛn de kɔntinyu fɔ twit, twitch, ɔ twitch. Sɔm pipul dɛn kin tɔk bɔt am se i "lɛk wom we de kray ɔnda di skin."
• I nɔ izi fɔ tɔk ɔ blo if di tɔnsil dɛn na di trot afɛkt.

Imajin, ivin we yu jɔs tinap, wan smɔl bɔdi we de na yu an ɔ yu leg kin kɔntinyu fɔ twit, lɛk se sɔntin we de insay de twit. Aw i go anɔynt if dis nɔ stɔp ivin we yu de go slip na nɛt? Na dat na wetin myokymia bi.

Aw dɛn kin no se pɔsin gɛt dis sik we dɛn kɔl Isaacs’ Syndrome?

Yu dɔktɔ kin tɛl yu fɔ du sɔm tɛst fɔ no if yu gɛt Ayzaks sik ɛn fɔ mek yu nɔ gɛt ɔda sik dɛn. Sɔm pan dɛn tin ya na:

• Blɔd tɛst: Dɛn tin ya kin ɛp fɔ no sɔm patikyula kayn antibodi dɛm na di blɔd fɔ lɛk af pan pipul dɛm wae gɛt Isaacs’ syndrome.
• Nεv kכndukshכn stכdi εn εlektromayogram (EMG): Dɛn tεst ya de mכsu aw yu mכsul dεm εn nεv dεm de wok, jכs lεk aw ilektrikian de chεk di kכrant we de insay waya.
• Imej stכdi lεk CT skan כ MRI skan: Dis kin luk insay di bכdi fכ si if כda prכblεm de.

Sɔntɛnde, dɛn kin kɔnfyus di sik we dɛn kɔl Isaacs’ syndrome wit ɔda tin dɛn lɛk stiff person syndrome , rippling muscle syndrome , ɔ cramp-fasciculation syndrome, so i impɔtant fɔ no di sik kɔrɛkt wan.

Aw dɛn kin trit di sik we dɛn kɔl Isaacs’ Syndrome?

Naw, no mɛrɛsin nɔ de fɔ dis sik. Di tritmɛnt na fɔ kɔntrol yu sik ɛn ɛp yu fɔ wok fayn fayn wan.

If Isaacs’ syndrome gɛt fɔ du wit ɔda ɔtoimyun sik ɔ malignancy, i impɔtant bak fɔ trit di ɔndalayn kɔndishɔn.

Yu dɔktɔ kin tɛl yu fɔ du dɛn tritmɛnt ya fɔ di sik we dɛn kɔl Isaacs’ syndrome:

• Di mɛrɛsin dɛn we de mek pɔsin nɔ fil bad: Fɔ ɛgzampul, mɛrɛsin dɛn lɛk phenytoin ɛn carbamazepine. Dɛn tin ya kin mek di mɔsul dɛn kin swɛt, dɛn kin shek, ɛn dɛn kin mek dɛn fil pen.
• Immunosuppressive medications: Drugs lɛk azathioprine ɛn methotrexate de wok bay we dɛn de kɔntrol di imyun sistɛm fɔ mek i nɔ du tin di rayt we.
• Intravenous immunoglobulin (IVIG): dis involv fכ gi sכlushכn we gεt antibodi dεm frכm hεlty dכna dεm insay di bכdi tru wan vein.
• Kɔtikosterɔyd dɛn we dɛn kin tek bay mɔt: Fɔ ɛgzampul, prɛdnisolon.
• Plasma ɛkshɛnj: .Dis na we fɔ filta di pɔyzin ɛn dɛn bad bad antibodi dɛm frɔm di blɔd fɔ pipul dɛm we gɛt abnɔmal antibodi dɛm.

Yu tink se dɛn kin ebul fɔ avɔyd di sik we dɛn kɔl Isaacs’ Syndrome?

Bikɔs sayɛnsman dɛn stil nɔ ɔndastand gud gud wan wetin kin mek dis apin, naw, no we nɔ de fɔ mek dɛn nɔ du dis.

Wetin na de luk fɔ pipul dɛm wae gɛt nyuromyotonia?

De luk fɔ pɔrsin wae gɛt dis sik kin difrɛn. E kin dipen pan aw de sik kin tranga, de tin wae kin mek pɔrsin gɛt dis sik, aw tritmɛnt kin woke fayn, ɛn ɔda mɛrɛsin wae gɛt fɔ du wit am.

Di nyuromyotonia simptom dɛm kin wɔs smɔl smɔl as tɛm de go. Dɛn kin rili stɔp fɔ muv ɛn ambɔg di tin dɛn we dɛn kin du ɛvride.

Dis min se wetin fɔs i tan lɛk se na smɔl mɔsul dɛn we de spam kin leta so bad dat i nɔ kin izi fɔ waka. So, i impɔtant fɔ no di sik kwik kwik wan ɛn bigin fɔ trit am.

Pan ɔl we naw, dɛn nɔr dɔn gɛt kɔmplit mɛrɛsin, dis sik nɔr kin kil pɔrsin.

Wetin a fɔ du fɔ liv fayn wit di sik we dɛn kɔl Isaacs’ Syndrome?

Fɔ liv wit dis sik kin tranga, bɔt sɔm pipul dɛn dɔn si se dɛn dɔn gɛt sakrifays fɔ kɔntrol di prɔblɛm dɛn we kin apin to dɛn bɔdi ɛn maynd bay we dɛn de du dɛn tin ya:

• Fɔ advatayz fɔ pipul dɛm wae gɛt nyuromɔskular disɔda: fɔ tek pat pan awɛns program ɛn fɔ tich ɔda pipul dɛm bɔt dis.
• Fɔ atɛnd di kɔyl sɛshɔn dɛm: Yu kin lan di strateji dɛm wae yu nid fɔ bia wit dis situeshɔn na yu maynd.
• Fɔ kɔnɛkt wit ɔda pipul dɛn we gɛt di sem kayn tin: Ɛspɛshali tru soshal midia. Na big trɛnk fɔ fil lɛk se nɔto yu wan de.
• Fɔ tink gud wan.
• Fɔ praktis yoga.
• We yu de waka: I impɔtant fɔ mek yu de du tin dɛn we yu go ebul fɔ du.

Wetin ɔda tin a kin aks mi dɔktɔ bɔt di sik we dɛn kɔl Isaacs’ Syndrome?

If dɛn no se yu gɛt nyuromyotonia ɔ Isaacs’ syndrome, mek shɔ se yu aks yu dɔktɔ dɛn kwɛstyɔn ya:

• Wetin mek a bin gɛt di sik we dɛn kɔl Isaacs?
• A gɛt ɛni ɔda mɛrɛsin we gɛt fɔ du wit dis?
• Aw wi go no fɔ tru se dis na Ayzaks in sindrom ɛn nɔto ɔda nyuromɔskular sik lɛk ALS (Amyotrophic Lateral Sclerosis)?
• Us pat dɛn na mi bɔdi dis kin afɛkt?
• Us tritmɛnt dɛn yu kin advays?
• A fit fɔ gɛt ɛni klinik trial?
• Yu tink se fizik tɛrapi ɔ ɔkupeshɔn tɛrapi go ɛp mi?
• Yu kin rifer mi to advays ɔ sɔpɔt grup fɔ ɛp mi fɔ bia wit dis prɔblɛm?
• Yu tink se ɛni ɔda pɔsin na mi famili nid fɔ tɛst fɔ no if i gɛt Ayzaks sik?

Fɔ dɔn, wetin fɔ mɛmba (Take-Home Message) .

Isaacs’ syndrome na wan nyuromɔskular disɔda we nɔ kin apin so ɔltɛm we kin mek di nerv ɛn mɔsul dɛn wok pasmak. If dɛn no se yu gɛt dis sik, nɔ panik, bɔt mek shɔ se yu tɔk to yu dɔktɔ. I kin chɛk fɔ ɔda tin dɛn we gɛt fɔ du wit dis ɛn ɛp yu fɔ kɔntrol di sayn dɛm lɛk we yu mɔsul dɛn de twitch ɛn stiff. Mɛmba se, if yu gɛt di rayt tritmɛnt ɛn sɔpɔt, yu kin liv fayn layf wit dis sik.

Isaacs ’ syndrome, neuromyotonia, mɔsul dɛn pen, mɔsul dɛn de twitch, nyurolɔjik sik