If yu ɔ pɔsin we yu lɛk gɛt Sistik Faybrosis (CF), yu go mɔs no gud gud wan di prɔblɛm dɛn we kin apin we pɔsin liv wit am. Bɔt di gud nyus na dat, we di sayɛns bɔt mɛrɛsin dɔn go bifo, nyu mɛrɛsin dɛn de naw we go ɛp yu fɔ bia wit dis sik. Tide, wi go tɔk bɔt wan pan dɛn kayn drɔgs ya. Dɛn kɔl am Ivacaftor. Yu kin sabi am wit di brand nem Kalydeco. Lɛ wi tek wan kwik luk pan dis drɔg.
Wetin kin rili apin wit dis mɛrɛsin?
Fɔ tɔk am simpul wan, Ivacaftor na wan mɛrɛsin we dɛn kin yuz fɔ mɛn Sistik Faybrosis (CF) . Bɔt i nɔ fayn fɔ ɔl di wan dɛn we gɛt CF. Dis dכg de wok כnli pan pipul dεm we gεt spεshal mכtεshכn na di jin dεm we de mek CF. Yu dɔktɔ go du di tɛst dɛn we yu nid fɔ no if dis mɛrɛsin fayn fɔ yu.
Sistik Faybrosis na wan sik we de kɔmɔt pan jɛnɛtiks we de mek wan prɔtin na wi bɔdi nɔ wok fayn. dis kin mek tik tik stika sekreshכn dεm kin kכmכt na כgan dεm lεk di lכng εn pankrias, we kin mek difrεn kכmplikεshכn dεm. di drog Ivacaftor de wok bay we i de mek di protin we dεn pwεl wok bak to sכm mak, i de tכn di sekreshכn dεm εn alaw dεm fכ pul dεm izi wan na di bכdi.
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu bigin fɔ tek mɛrɛsin
Bifo yu yuz dis mɛrɛsin, i rili impɔtant fɔ gi yu dɔktɔ klia pikchɔ bɔt yu ɔl wɛlbɔdi. Mek shɔ se yu tɛl dɛn bɔt dɛn tin ya mɔ:
- Liva sik: I impɔtant fɔ tɛl yu dɔktɔ if yu gɛt ɛni liva sik. Dis na bikɔs na di liva de mɛtabolayz dis mɛrɛsin mɔ. If yu gɛt prɔblɛm wit yu liva, yu dɔktɔ go nid fɔ ajɔst yu doz.
- Kidni sik: Semweso, if yu gɛt kidni prɔblɛm, tɛl wi bɔt dat bak.
- Alɛji: Tɛl yu dɔktɔ if yu gɛt ɛni alɛji to Ivacaftor ɔ ɛni ɔda mɛrɛsin, it, ɔ day.
- Bɛlɛ ɔ plan fɔ bɔn pikin: If yu gɛt bɛlɛ ɔ yu de tray fɔ gɛt bɛlɛ, tɛl yu dɔktɔ.
- If yu na mama we de gi pikin in bɛlɛ: Mek shɔ se yu tɔk bɔt dis if yu de gi pikin in bɛlɛ.
Na fɔ yu yon sef fɔ tɛl di dɔktɔ we yu nɔ ayd dis infɔmeshɔn. So nɔ fɔgɛt fɔ tɛl am ilɛksɛf na smɔl tin.
Aw ɛksaktɔli a kin yuz dis mɛrɛsin?
Fɔ mek yu gɛt di bɛst pan di mɛrɛsin, i rili impɔtant fɔ yuz am di rayt we.
Aw fɔ tek di mɛrɛsin
Dis mɛrɛsin yaI fɔ rili tek am wit it we gɛt fat. Fɔ ɛgzampul, if yu tek dis pil wit sɔntin lɛk eg, chiz tost, slais bred wit pinat bɔta, ɔ ɔmɛlet we dɛn mek wit bɔta, di bɔdi go tek di mɛrɛsin bɛtɛ. Nɔ tek am we yu ɛmti bɛlɛ.
Di tin we impɔtant pas ɔl: Nɔ tek dis mɛrɛsin wit grep jus fɔ ɛni rizin. Seville orenj dem tu no gud. Dɛn tin ya kin afɛkt di we aw di mɛrɛsin de wok fayn.
Tek di doz we dɛn dɔn tɛl yu nɔmɔ, we yu dɔktɔ tɛl yu fɔ tek am. Nɔ tek mɔ. Nɔ stɔp fɔ tek di mɛrɛsin wantɛm wantɛm if yu dɔktɔ nɔ advays yu.
If yu gi am to pikin dɛn
Sɔntɛnde, dɛn kin gi dis mɛrɛsin fɔ pikin dɛn we dɔn pas 6. Bɔt, tek tɛm tɔk to yu dɔktɔ we de mɛn pikin dɛn bɔt am ɛn fala wetin i tɛl yu fɔ du.
If dɛn ad di doz fɔ di mɛrɛsin (Overdose) .
If yu tink se yu dɔn tek bɔku mɛrɛsin, go na di Imejɛnsi Tritmɛnt Yunit (ETU) we de nia yu wantɛm wantɛm . Ɔ kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital fɔ advays.
If yu mis wan doz fɔ mɛrɛsin
If yu mis wan doz, tek am jɔs afta yu mɛmba. Bɔt if i nɔ rich 6 awa te yu tek yu nɛks doz, skip di doz we yu mis ɛn tek yu nɛks doz di tɛm we yu dɔn sɛtul. Nɔ ɛva tek dabl doz.
Ɔda mɛrɛsin dɛm wae kin intarakt wit Ivacaftor
I rili impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek, lɛk vaytamɛn ɛn ɛbul prɔdak dɛm. Sɔm mɛrɛsin kin miks wit Ivacaftor. Si dis tebul.
| Tayp fɔ mɛrɛsin/sɔbstans | Level fɔ wɔri bɔt |
|---|---|
| Sɔm mɛrɛsin dɛn we dɛn kin yuz fɔ mek pɔsin sik (e.g. carbamazepine, phenobarbital, phenytoin) . | Ridyus di effektiv we Ivacaftor de wok. |
| Grepfruit jus ɛn Sɛvil ɔrɛnj dɛn | I nɔ nid fɔ mek di mɛrɛsin go ɔp. |
| Rifampin, Rifabutin (mɛrɛsin fɔ TB) . | I de ridyus di effektiv we Ivacaftor de du bad bad wan. |
| St. John’s Wort (prɔdak we dɛn mek wit ɛbul) . | Ridyus di effektiv we Ivacaftor de wok. |
| Antifכngal dεm (e.g. kεtokonazכl, itrakonazכl, flukonazכl) . | Ivacaftor konsantreshכn kin inkrεs. |
| Sɔm antibayɔtiks (e.g. klarithromycin, erythromycin) . | Ivacaftor konsantreshכn kin inkrεs. |
| Sayklɔspɔrin, Takrɔlimus, Digɔksin | Ivacaftor kin afɛkt di we aw dɛn mɛrɛsin ya de wok fayn. |
Dis list nɔ kɔmplit, so i bɛtɛ fɔ tɛl yu dɔktɔ bɔt ɔltin we yu de tek.
Sɔm sayd ɛfɛkt dɛn we pɔsin kin gɛt we i tek di mɛrɛsin
Lɛk ɛni mɛrɛsin, Ivacaftor kin mek sɔm pipul dɛn gɛt sayd ɛfɛkt. Sɔm pan dɛn tin ya siriɔs, ɛn ɔda wan dɛn nɔ kin at fɔ du.
| If yu gɛt dɛn sik ya, tɛl yu dɔktɔ wantɛm wantɛm. | |
|---|---|
| Di sayn dɛn we de sho se pɔsin gɛt alɛji | Skin rash, it, swel na di fes, lip ɔ tong. |
| Di tin dɛn we kin apin to di liva | di urine we dak, di stɔl we gɛt layt kɔlɔ, di yay ɔ di skin we de yɔlɔ, pen na di ɔp rayt pat na di bɛlɛ, i nɔ de want fɔ it. |
| Vishɔn kin chenj | Blɔr vishɔn ɔ ɛni ɔda chenj. |
| Ɔda | Fɔ fil taya bad bad wan, fil lɛk se yu gɛt fiva. |
| Bɔku tɛm, dɛn tin ya nɔ kin siriɔs, bɔt if dɛn kɔntinyu fɔ de, tɛl yu dɔktɔ. | |
| Dijestiv sistɛm | Nɔ digest, nɔs, dayarɛa. |
| Ɔda | Ed pen , diziz , jɔyn pen. |
We yu de tek dis mɛrɛsin, yu dɔktɔ go nid fɔ chɛk yu yay ɛn di lɛvɛl we di liva ɛnzaym dɛn de na yu blɔd ɔltɛm. Dis na nɔmal tin.
Aw fɔ kip mɛrɛsin sef?
- Kip fa frɔm pikin dɛn.
- Stɔr na rum tɛmpracha (bitwin 15-30 digri sɛlshiɔs).
- Trowe di mɛrɛsin we dɔn pas ɛn yu nɔ yuz am.
Dɛn dɔn gi yu dis mɛrɛsin fɔ yu nɔmɔ. Nɔ sheb am wit ɛni ɔda pɔsin fɔ ɛni rizin.
Mɛsej we dɛn kin kɛr go na os
- Ivacaftor na spɛshal mɛrɛsin we dɛn kin gi fɔ trit sɔm kayn sistik fibrosis.
- Dɛn fɔ tek dis mɛrɛsin ɔltɛm wit it we gɛt fat.Tek am. Nɔ ɛva tek am wit grep jus.
- Tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn we yu de tek ɛn ɔl yu ɔda sik dɛn.
- If yu gɛt ɛni siriɔs sayd ɛfɛkt, lɛk we yu yay yɔlɔ, yu urine dak, ɔ yu skin de rɔsh, tɛl yu dɔktɔ wantɛm wantɛm.
- Dis mɛrɛsin na fɔ yu nɔmɔ. Nɔ gi am to ɛni ɔda pɔsin. If yu gɛt ɛni kwɛstyɔn, tɔk to yu dɔktɔ ɔltɛm.
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