Lɛ wi lan bɔt wan mɔsul bayɔpsi. Yu tink se yusɛf go nid dis?

Yu dɔn ɛva yɛri bɔt ‘Muscle Biopsy’? Sɔntɛm yu ɔ pɔsin we yu sabi dɔn tɛl yu fɔ du dis. Wetin rili na am? Wetin mek dɛn kin du am? Lɛ wi tɔk bɔt am simpul wan, so dat yu go ɔndastand. Nɔr nid fɔ frayd, bɔrku tɛm dɛn kin du am fɔ ɛp fɔ no ustɛm na yu prɔblɛm.

Wetin na mɔsul bayɔpsi?

Fɔ tɔk am simpul wan, fɔ tek mɔsul bayɔpsi na we dɛn kin pul wan rili smɔl pat pan yu mɔsul, dat na, frɔm wan mɔsul na yu bɔdi, ɛn chɛk am. dis na fכ no if yu gεt εni spεshal sik (`myopathies`) we de afekt yu mכsul dεm. Wan dɔktɔ kin sɛn di skel mɔsul sɛmpul to wan lɛb. Na de, dɛn kin luk am ɔnda maykroskɔp fɔ si if ɛnitin de we nɔ fayn ɔ prɔblɛm de. I tan lɛk we yu kɔt wan klos ɛn chɛk fɔ si if di trɛd dɛn gud ɔ nɔ fayn.

Ustɛm a nid fɔ tek mɔsul bayɔpsi?

Imajin se yu dɔn de fil wik na yu mɔsul dɛm fɔ sɔm tɛm, ɔr yu mɔsul dɛm de gɛt sɔri, sɔri, ɔr gɛt sɔm ɔda sayn dɛm wae nɔr kɔmɔn (simptom dɛm fɔ `myopathy`). Dɔn dɔktɔ go tɛl yu se yu nid fɔ du dis bayɔpsi. Bɔt dɛn nɔ go du am wantɛm wantɛm.

Bɔku tɛm, dɔktɔ dɛn kin du sɔm ɔda tɛst dɛn fɔs:

• Fyzikal ɛn nyurolɔjik ɛgzam : Dɛn go chɛk yu gud gud wan fɔ si aw yu nervɔs sistɛm de wok.
• Blɔd tɛst : Fɔ ɛgzampul, dɛn kin du tɛst we de luk wan ɛnzaym we dɛn kɔl kriaytin kinaz, ɔ tɛst fɔ di jɛnɛtiks.
• Imej tɛst : Tin dɛn lɛk MRI skan ɛn CT skan.
• Nεv kכndukshכn stכdi dεm εn εlektromayografi (EMG) : dεn ya de luk aw mεsej dεm de fכlכ bitwin yu nεv dεm εn mכsul dεm, εn aw dεn de wok.

Ivin wit dɛn tɛst ya, sɔntɛnde dɛn nɔ kin no di rayt tin we mek pɔsin gɛt di sik. Na da tɛm de dɔktɔ dɛn kin ɔda fɔ mek dɛn tek di mɔsul dɛn bayɔpsi fɔ no mɔ ɛn fɔ no if i gɛt di sik klia wan .

Yu kin nid fɔ tek yu mɔsul bayɔpsi if yu dɔktɔ sɔprayz se yu gɛt ɛni wan pan dɛn tin ya:

• di mכskul dεm : εgzampl dεm na Duchenne mכskul distrofi, Becker mכskul distrofi, εn myotonic distrofi.
• Parasayt infεkshכn : Infεkshכn lεk trichinosis εn toxoplasmosis we de afekt yu mכsul dεm.
• inflammatory muscle kondishכn dεm: lεk polymyositis εn dεrmatomyositis.
• mεtabolik myopathies : fכ egzampl, Pompe sik εn כda sik dεm we de stכr glycogen.
• Congenital myopathies : Kכndishכn dεm we de we dεn bכn am, lεk nemaline myopathy.
• Toxic myopathies : Na tin wae kin apin wae yu de yuse sɔm mɛrɛsin fɔ lɔng tɛm, fɔ ɛgzampul stεrɔyd ɔr statin.

Us mɔsul dɛn kin pik fɔ mek dɛn du bayɔpsi?

Dɛn kin tek dis bayɔpsi frɔm wan pan sɔm patikyula mɔsul dɛn na yu bɔdi. Di wan dɛn we bɔku pipul dɛn kin gɛt na:

• Kwadrisɛps : Na di big mɔsul grup we de bifo yu shɔl.
• Deltoid : Na di mכsul we de kכnekt di fכnt, sayd, εn bak pat pan yu sכlda.
• Bicep : Na di mכsul we de fכnt pan yu כp an, bitwin di sכlda εn di εlbo.

Di dɔktɔ go want fɔ mek shɔ se di mɔsul we dɛn pik fɔ bayɔpsi nɔ tu wik ɔ gɛt ɔda sayn dɛn. Bɔt di dɔktɔ go want fɔ mek shɔ bak se di mɔsul nɔ tu wik, dɛn nɔ jɔs dɔn injɛkt am, ɔ i nɔ wund. Dis kin afɛkt di rizɔlt fɔ di bayɔpsi ɛn i nɔ kin gi kɔrɛkt infɔmeshɔn.

Aw a fɔ rɛdi fɔ mek dɛn tek mi mɔsul bayɔpsi?

Yu dɔktɔ go ɛksplen to yu di bayɔpsi ditayli ɛn gi yu instrɔkshɔn bɔt aw fɔ pripia. I rili impɔtant fɔ fala dɛn instrɔkshɔn ya di rayt we. If yu nɔ ɔndastand sɔntin ɔ yu gɛt ɛni kwɛstyɔn, nɔ fred fɔ aks yu dɔktɔ.

Jɛnɛral wan, yu fɔ tek tɛm wit dɛn tin ya:

• If yu dɔn gɛt ɛni mɔsul injɛkshɔn, mɔsul tɛst lɛk EMG, ɔ ɛni injuri na yu mɔsul dɛn insay di las siks mɔnt, yu fɔ rili tɛl yu dɔktɔ.
• Yu dɔktɔ kin tɛl yu fɔ stɔp fɔ tek mɛrɛsin dɛn we de mek yu nɔ gɛt blɔd lɛk aspirin sɔm dez bifo dɛn du di bayɔpsi fɔ mek yu nɔ gɛt prɔblɛm wit blɔd. Bɔt, i bɛtɛ fɔ lɛ yu nɔ stɔp fɔ tek ɛni mɛrɛsin te yu dɔktɔ tɛl yu fɔ tek am.
• Dɛn kin aks yu fɔ fast fɔ sɔm awa bifo dɛn du di bayɔpsi, we yu nɔ it ɔ drink ɛnitin (eksept wata).
• If dɛn gi yu sɛdeshɔn ɔ jenɛral anestezi we dɛn de du dis, yu go nid pɔsin fɔ kɛr yu go na os afta di bayɔpsi.

Wetin na di we aw dɛn kin du di mɔsul bayɔpsi?

di step dεm fכ mכsul bayopsi de difrεn sכmtεm dipכnt pan di mεtכd we dεn yuz. tu men we dεm de: wan ``open`` bayopsi εn wan ``nidul`` bayopsi. Ɛni we, dɛn kin gi yu (ɔ yu pikin) ``sedation`` ɔ ``general anesthesia`` bifo tɛm.

Aw fɔ du wan opin mɔsul bayɔpsi

di step dεm fכ opin mכsul bayopsi kin bi lεk dis:

• Fɔs, di dɔktɔ kin klin di say we dɛn kɔt am fayn fayn wan wit wan antiseptik sɔlvushɔn.
• Dɔn, dɛn kin injɛkt wan lokal anestetik na di say, so yu nɔ go fil ɛni pen we dɛn kɔt di say.
• Neks, dɛn go kɔt wan say we lɔng lɛk 4 to 6 sɛntimita na yu skin.
• di dכkta go separet yu skin, di layεr fεt כnda di skin (subcutaneous fat), εn di mεmbran we de kכba di mכsul dεm (muscle fascia - wan kכnektiv tisu), εn afta dat i go muf go na di mכsul we de כnda.
• Frɔm de, dɛn kin kɔt wan smɔl sampul pan di mɔsul tisu.
• Dɔn di dɔktɔ kin lɔk di mɔsul mɛmbran ɛn di skin bak wit suture.
• Dɛn kin kɔba di wund wit mɛrɛsin ɛn bandej ɛn goz.

Aw fɔ du nidul mɔsul bayɔpsi

di step dεm fכ nidul mכsul bayopsi kin bi lεk dis:

• Di dɔktɔ kin klin di say we dɛn tek di bayɔpsi fɔs wit wan antiseptik sɔlvushɔn.
• Dɔn dɛn kin injɛkt wan lokal anestetik, so yu nɔ go fil ɛni pen we dɛn de du di bayɔpsi.
• Di dɔktɔ go mek wan rili smɔl say na yu skin.
• Neks, dɛn kin put spɛshal nidul bayɔpsi inschrumɛnt tru di smɔl say we dɛn kɔt. Bɔku tɛm, dis kin tan lɛk pensil.
• Dɛn kin yuz ɔltra saund mashin (ultrasound imaging) fɔ gayd dis divays prɛsishɔn to di mɔsul.
• Dɔn di dɔktɔ kin yuz di inschrumɛnt fɔ kɔt sɔm smɔl smɔl pat dɛn na di mɔsul. Bɔku tɛm, dɛn kin tek lɛk 3 ɔ 4 sɛmpul dɛn.
• Afta dɛn dɔn pul di tisu we dɛn nid, dɛn kin pul di inschrumɛnt, dɛn kin prɛs di say fɔ sɔm tɛm fɔ mek di blɔd nɔ kɔmɔt, dɛn kin put mɛrɛsin na di wund, ɛn dɛn kin kɔba goz ɛn bandej dɛn.

Aw dis kin mek pɔsin fil bad?

If dɛn du dis bayɔpsi ɔnda jenɛral anestezi, yu nɔ go fil ɛni pen. If yu mek dɛn du am ɔnda lokal anestezi, di pen go smɔl, ɔ ivin nɔ go de. Bɔt yu kin fil se yu de pinch ɔ pul smɔl.

Afta di bayɔpsi, yu kin fil sɔm smɔl pen na di say we dɛn tek di bayɔpsi fɔ lɛk tu to tri dez. Ɛspɛshali if yu bin gɛt opin bayɔpsi, di say kin at fɔ lɛk wan wik so. Sɔm brus dɛn kin de bak rawnd di sayt.

I bɛtɛ fɔ aks yu dɔktɔ bɔt wetin dɛn kin du fɔ di pen ɛn us kayn mɛrɛsin yu fɔ tek.

Wetin kin apin afta dɛn dɔn du di bayɔpsi?

If dɛn gi yu sɛdeshɔn ɔ jenɛral anestezi, dɛn go kɛr yu go na rum fɔ wɛl fɔ shɔt tɛm afta dɛn dɔn du di bayɔpsi. Yu go de de te di tin dɛn we di mɛrɛsin kin du to yu dɔn. Dɔn yu kin go na os, bɔt yu fɔ mek ɔda pɔsin drayv yu go na os. Yu dɔktɔ go gi yu instrɔkshɔn bɔt aw fɔ kia fɔ di bayɔpsi wund.

di dכkta de yuz spεshal kεmikכl dεm fכ friz di mכsul sεmpl we dεn tek frכm di bayopsi kwik kwik wan (`flash freeze`). Dɛn kin du dis fɔ mek di tisu nɔ pwɛl ɛn fɔ mek i fayn fɔ ɛgzamin. Dɔn dɛn kin sɛn am na wan lɛb. wan `pathologist de we spεshal pan nyuromכskular sik dεm`. I go tek tɛm luk di sampul ɔnda maykroskɔp. Sɔntɛnde, di spɛshal pɔsin go du ɔda tɛst dɛn pan di sampul. fכ egzampl, dεn go yuz spεshal day (`stains`) כ chεk fכ sכm `antibodi`.

Ɛni risk de fɔ mek dɛn tek di mɔsul dɛn bayɔpsi?

Kɔmplikɛshɔn dɛn we kin kam frɔm di mɔsul bayɔpsi nɔ kin rili apin. Bɔt sɔm tin dɛn de we kin apin we nɔ kin apin so ɔltɛm:

• Infεkshכn na di wund.
• di mכsul dεm we de kכmכt tru di wund (`mכsul hεnia`).
• Fɔ opin di wund bak afta di stich dɛn dɔn lɔs.
• Aksidɛntal injuri na fɔ pwɛl yu mɔsul, nerv, ɔ blɔd vesel we yu nɔ bin want.

Wan ska kin de na di say we dɛn tek di bayɔpsi. Sɔm pipul dɛn skin kin gɛt skata izi wan pas ɔda pipul dɛn.

Ustɛm a go gɛt di ripɔt?

Afta dɛn dɔn du bayɔpsi, i go bi se fɔ wet fɔ di rizɔlt na di tin we at pas ɔl. Yu dɔktɔ go ɛksplen aw ɛn ustɛm yu go gɛt di ripɔt. I kin tek sɔm dez, ɔ i kin tek pas wan wik. If di ripɔt nɔ kam bak bay di de we yu dɔktɔ se, kɔl yu dɔktɔ bak ɛn aks bɔt am.

Wetin di ripɔt tɔk bɔt?

di mכsul bayopsi ripot gεt di ditel dεm bכt di kכntribyushכn dεm fכ di mכsul sεmpl we dεn tek. Dis kin inklud tin dɛn lɛk:

• tin dεm lεk di strכkchכ fכ di mכsul fayb dεm (i.e. di mכsul sεl dεm), aw dεn hεlty, εn dεn "ej".
• di ditel dεm bכt di כda sεl dεm na da tisu de, fכ egzampl, di nεv sεl dεm (nyuron dεm).
• tin dεm lεk inflameshn, maytochכndrial abnכmaliti, glycogen εn lipid stכrej abnכmaliti.

Yu dɔktɔ go ɛksplen to yu wetin de insay dis ripɔt ɛn wetin i min.

Sɔntɛnde, di bayɔpsi kin luk nɔrmal, ɔr kin gɛt smɔl smɔl sayn dɛm fɔ di sik. insay dis kes, sכmtεm dεn kin kכl am "unspecified myopathy." Dis na bikɔs di bayɔpsi nɔ go dɔn fɛn di rayt say we di sik de, ɔ di sik kin stil de na in fɔs stej. If dis apin, yu kin gɛt fɔ du ɔda mɔsul bayɔpsi.

If prɔblɛm de wit di ripɔt, wetin yu go du nɛks?

di rizulεt dεm fכ mכsul bayopsi kin plεnti tεm fכ no wan spεsifi k mכsul sik (`myopathy`).

If dɛn no se yu gɛt wan patikyula sik, yu dɔktɔ go ɛksplen am to yu ɛn tɔk bɔt wetin yu nid fɔ du nɛks. Tugeda, una go mek wan tritmɛnt plan we go woke fayn fɔ una. Nɔ wɔri, yu dɔktɔ go ɛp yu.

Ustɛm yu nid fɔ tɔk to di dɔktɔ?

If yu notis wan ɔ mɔ pan dɛn sayn ya we de sho se yu bayɔpsi sayt gɛt di sik, yu fɔ kɔl yu dɔktɔ wantɛm wantɛm:

• Fɔ swel rawnd di wund, fɔ rɛd, ɔ fɔ chenj di kɔlɔ na di skin na nɔmal tin.
• Di skin we de rawnd di wund kin fil wam pas ɔda say dɛn.
• Pus ɔ ɔda wata we de kɔmɔt na di wund (`Pus ɔ drenaj`).
• Fɔ gɛt fiva.
• Fɔ fil taya pasmak (`Fatigue`).

Yu tink se we yu tek mɔsul bayɔpsi, yu go ebul fɔ no se yu gɛt MS (Multiple Sclerosis)?

Dɛn nɔ kin yuz mɔsul bayɔpsi fɔ kɔnfɔm di diagnosis fɔ MS (Multiple Sclerosis). Bɔt dɔktɔ kin se dɛn fɔ tek dis bayɔpsi fɔ mek dɛn nɔ gɛt ɔda sik dɛn we gɛt di sem sayn dɛn we gɛt di sem sayn dɛn we gɛt fɔ du wit MS.

Na nɔmal tin fɔ fil fɔ fred ɛn wɔri we yu kam fɔ no se yu nid fɔ gɛt mɔsul bayɔpsi. Ɛn i nɔmal bak fɔ fil wɔri we yu de wet fɔ di rizɔlt. Yu dɔktɔ go no ɔl di sayd ɛfɛkt dɛn we dis bayɔpsi kin gɛt, so nɔ fred fɔ aks ɛni kwɛstyɔn we yu go gɛt. If yu bayɔpsi ripɔt sho se sɔntin nɔ rayt, tray fɔ tink bɔt am as di fɔs tin we yu fɔ du fɔ mek yu wɛl. Yu dɔktɔ go wok wit yu fɔ disayd fɔ du impɔtant tin dɛn bɔt yu wɛlbɔdi biznɛs.

Wetin na di impɔtant tin we wi fɔ kɛr go na os frɔm dis stori?

Okay, so di impɔtant tin fɔ mɛmba frɔm wetin wi dɔn tɔk bɔt na dat, mɔsul bayɔpsi na rili impɔtant tɛst we de ɛp fɔ no kɔrɛkt wan prɔblɛm ɔ sik na yu mɔsul dɛm.

Dis kin tan lɛk se i de mek yu fred smɔl. Bɔt i kin ɛp yu fɔ no di kɔrɛkt tin ɛn bigin di rayt tritmɛnt fɔ yu. If yu gɛt ɛni kwɛstyɔn ɔ tin we de mɔna yu, mek shɔ se yu tɔk bɔt am wit yu dɔktɔ. Mɛmba se dis na impɔtant tin fɔ ɔndastand yu sik ɛn fɔ mɛn am fayn fayn wan.

` Mɔsul Bayɔpsi, Mɔsul Bayɔpsi, mayopati, mɔsul wik, mɔsul sik, diagnosis, mɛdikal tɛst, ɔpreshɔn