Sɔntɛnde yu kin fil lɛk se yu fayn we yu wek na mɔnin, bɔt as di de de go, yu bɔdi kin bigin fɔ lɔs ɛnaji? Ɛspɛshali we yu yaylid dɛn fil ebi ɛn drɔp, yu wɔd dɛn kin slɔp we yu de tɔk, ɔ i nɔ kin izi fɔ yu fɔ ivin es yu an ɔ yu leg? If dɛn tin ya na tin wae yu sabi, e fayn fɔ mek yu no bɔt de sik wae wi de tɔk bɔt tide, wae dɛn kɔl Myasthenia Gravis , ɔr MG fɔ shɔt.
Fɔ tɔk am simpul wan, wetin na Myasthenia Gravis?
Dis na ɔtoimyun sik wae kin las fɔ ɔl yu layf. Fɔ tɔk am simpul wan, di difɛns sistɛm we wi bɔdi de fɛt, we na di imyun sistɛm, kin mistek bigin fɔ atak di pat dɛn we gɛt wɛlbɔdi na wi yon bɔdi. insay MG, dis atak de tכk di kכnεkshכn bitwin wi nεv dεm εn mכsul dεm.
Imajin, wi bren de tɛl wan mɔsul se, "Okay, naw yu go kɔntrakt." Dis mɛsej fɔ travul along di nerves ɛn rich di mɔsul. bכt insay pכsin we gεt MG, di "rεsεpכta dεm" usay dεn de kכri dis mεsej de disrupt bay dεn כwn imyun sistεm. I tan lɛk se yu lɔs di signal we yu de tray fɔ kɔl pɔsin na fon.
Dis kin mek di sayn dɛn we dɛn kin sɛn to di mɔsul dɛn kin wik as dɛn de yuz dɛn, ɛn smɔl smɔl di mɔsul dɛn kin lɔs dɛn trɛnk. Bɔt afta dɛn dɔn rɛst fɔ shɔt tɛm, dɛn kin kam bak to dɛn nɔmal. Dis na di tin we difrɛn pas ɔl pan MG. Pan ɔl we dis sik kin apin pan ɛni ej, i kin apin mɔ pan uman dɛn we nɔ rich 40 ia ɛn man dɛn we dɔn pas 60 ia.
Wetin mek wi bɔdi de du dis to insɛf? Wetin na di rizin dɛn?
i nכ rili no wetin mek di imyun sistεm de atak wi כwn nyuromכskular jכnkshכn dis we. bכt di men rizin na dat di bכdi de prodyuz antibodi dεm we de agens di rεsεpכta dεm we de gεt di nyurotransmitta asεtilkolin. dis asetilkolin na di "mεsenja" we de kכri di mεsej we de tεl di mכsul dεm fכ kכntrakt. So we dis mɛsenja in ples fɔ akshɔn blok, di mɔsul dɛn nɔ de wok fayn.
Sɔm pipul dɛn kin gɛt antibodi dɛn bak we de agens ɔda prɔtin dɛn. Pan ɔl we dɛn kin tink se dis kin gɛt sɔntin fɔ du wit dɛn jɛnɛtiks, bɔku pipul dɛn we gɛt MG nɔ kin gɛt ɔda pɔsin na dɛn famili we gɛt dis sik.
Dɔn bak, dɛn dɔn si se di taymus gland , we na wan ɔgan we de ɔp di chɛst, de involv. Dis gland de big pan sɔm pipul dɛm we gɛt MG. Risach pipul dɛn biliv se sɔntɛnde dis gland kin mek di bɔdi nɔ no di rayt tin ɛn mek i mek dɛn antibodi dɛn ya we dɛn nɔ want.
Wetin na di men sayn dɛm wae pɔrsin kin si?
Di sayn dɛm fɔ MG kin difrɛn frɔm wan pɔrsin to ɔda pɔrsin. Sɔm pipul dɛn kin gɛt dis sik wantɛm wantɛm. Ɔda pipul dɛn kin gɛt dɛn smɔl smɔl. Lɛ wi tek wan luk pan de men say dɛm wae pɔrsin gɛt dis sik ɛn wetin na de sayn dɛm.
| Di pat na di bɔdi we dɛn afɛkt | Di tin dɛn we pɔsin kin si |
|---|---|
| Di mɔsul dɛn na di yay |
(Fɔ bɔku pipul dɛn, di sik kin bigin wit dɛn sayn ya.) |
| Fes, mɔt ɛn trot |
|
| Nek, an ɛn fut | |
| Di mɔsul dɛn we de mek pɔsin ebul fɔ blo |
Imejɛnsi: Mayasthenia Krays
Sɔntɛnde, lɛk 15% to 20% pan di pipul dɛm we gɛt MG kin gɛt siriɔs wikɛd wik na dɛn trot ɛn di mɔsul dɛm we de blo. Dɛn kɔl dis wan myasthenia kraysis.Dis na mɛdikal imejensi. If yu gɛt ɛni prɔblɛm fɔ blo, go na di Imejɛnsi Dipatmɛnt (ETU) na di ɔspitul we de nia yu wantɛm wantɛm.
Aw yu go no fɔ tru se dis na sik?
If yu gɛt dɛn sik ya, yu fɔ go to yu famili dɔktɔ fɔs. If i saspek dis, i go rifer yu to nyurolɔjist. I go aks yu bɔt yu sik dɛn ɛn du yu bɔdi ɛgzam. Apat frɔm dat, sɔm tɛst dɛn de we dɛn kin du fɔ no if pɔsin gɛt di sik:
- Blɔd tɛst: Chɛk yu blɔd fɔ dɛn bad bad antibodi dɛm (acetylcholine receptor antibodies) we wi bin dɔn tɔk bɔt.
- Edrophonium test: Dis test de chɛk fɔ si if mɛrɛsin de mek yu mɔsul dɛn trɛnk fɔ sɔm tɛm. If trɛnk de go ɔp wantɛm wantɛm, i kin bi sayn fɔ MG.
- Nyurostimulashכn tεst dεm: dεn de put sכmכl nidul insay wan mכsul εn dεn de mכsu di spid we di nεv signal dεm de spid. dis kin yus fכ si aw kwik wan mכsul de wik we dεn de yuz am bכku bכku wan (εlektromayografi).
- Ays pak tɛst: Dɛn kin put ays pak pan aylid we de drɔp fɔ sɔm minit fɔ si if di aylid go ɔp. dis kin gi yu aidia fכ di kכndyushכn biכs di kol de mek di nyuromכskular kכmyunikeshn bכku fכ sכm tεm.
- Imej: We dɛn dɔn kɔnfyus di sik, dɛn kin du CT skan ɔ MRI skan fɔ chɛk fɔ ɛni prɔblɛm wit yu taymus gland, lɛk tumbu (taymoma).
Wetin na di tritmɛnt dɛn we dɛn kin gɛt?
MG na sik we dɛn nɔ kin ebul fɔ mɛn ɔl, bɔt dɛn kin ebul fɔ mɛn am fayn fayn wan. Yu dɔktɔ go pik di tritmɛnt we go fayn fɔ yu bay aw yu sik bad, yu ej, ɛn yu ɔl wɛl bɔdi.
1. Drug dεm we de mek di mכsul dεm strכng: Di fכs layn fכ tritmεnt na dεm lεk pyridostigmine. dis dεm de wok bay we dεn de inkrεs di amoun fכ asetilkolin na di nyuromכskular jכnkshכn. Dis drɔg de gi trɛnk insay 15-30 minit afta yu tek am, ɛn i kin las fɔ lɛk 3-4 awa.
2. Immune system suppressors: Bɔku pipul dɛn nid dɛn mɛrɛsin ya bikɔs na wi yon imyun sistɛm de mek wi gɛt di sik. Fɔs, dɛn kin gi dɛn stɛroyd lɛk prɛdnisɔn, dɔn dɛn kin chenj ɔda mɛrɛsin dɛn lɛk azathioprine. Dɛn tin ya kin tek sɔm mɔnt fɔ sho di rizɔlt.
3. Taymectomy: Ilɛksɛf tumbu de na di taymus gland ɔ nɔ de, we dɛn du ɔpreshɔn fɔ pul am, dat kin ridyus di sik dɛn we sɔm sik pipul dɛn kin gɛt bad bad wan.
4. IV Tɛrapi: .Dɛn kin gi dis tritmɛnt wae de sik kin rili bad, ɔr pan kes dɛm lɛk myasthenia crisis.
- Plasmapheresis: Wan spɛshal mashin de pul di bad bad antibodi dɛm na yu blɔd ɛn gi yu bɔdi bak we gɛt wɛlbɔdi.
- IVIG tεrapi: We dεn gi di antibodi dεm (immunoglobulin) we dεn tek frכm hεlty dona dεm to di bכdi, i de chenj di wok we di imyun sistεm de du fכ sכm tεm.
- monoklonal antibodi dεm: Dis na spεshal antibodi dεm we dεn mek na labכtכri we de tכk εn atak spεshal pat dεm na di imyun sistεm we nכ de wok fayn.
Aw yu fɔ kia fɔ yusɛf?
Apat frɔm di tritmɛnt we yu de gi yu, yu kin gɛt bɔku fridɔm frɔm smɔl chenj dɛn na yu layf.
- Gɛt gud it: It sɔm smɔl smɔl it dɛn ɔl di de pas fɔ it wan big it. It yu men it dɛn we yu gɛt mɔ trɛnk. Tɔk to yu dɔktɔ bɔt aw fɔ tek mɛrɛsin dɛn we de mek yu mɔsul dɛn strɔng bifo yu it.
- Ɛksesaiz, bɔt no wetin yu ebul fɔ du: Pan ɔl we ɛksesaiz kin gi yu trɛnk fɔ lɔng tɛm, nɔ fɔ tray tranga wan pasmak. Aks yu dɔktɔ ɔ pɔsin we de mɛn yu bɔdi us ɛgzampul dɛn we fayn fɔ yu.
- Rɛst we yu fil taya: Kɔntinyu fɔ du di tin dɛn we yu de du ɛvride. Bɔt jɔs afta yu bigin fɔ fil taya, tek smɔl tɛm fɔ blo. Lisin to yu bɔdi.
- No wetin kin mek dɛn gɛt di sik: Sɔm pipul dɛn kin gɛt inkris pan MG simptom dɛn we dɛn sik, we dɛn strɛs, we uman dɛn de gɛt mɔnt, ɛn bikɔs ɔf sɔm mɛrɛsin dɛn. Tɔk to yu dɔktɔ bɔt dis.
Mɛsej we dɛn kin kɛr go na os
- Myasthenia gravis (MG) nɔto sɔntin we yu de du. Na prɔblɛm wit yu bɔdi in imyun sistɛm.
- Di men sayn dɛm na we di mɔsul dɛn wik we de go ɔp as di de de go, mɔ di yaylid dɛn we de drɔp, we yu de si tu tɛm, ɛn i nɔ izi fɔ tɔk ɛn swɛla.
- If yu gɛt ɛni prɔblɛm fɔ blo, na imejensi. Go na ɔspitul in Imejɛnsi Dipatmɛnt (ETU) wantɛm wantɛm.
- Dis na sik we pɔsin kin rili ebul fɔ kɔntrol. Wok klos wit yu nyurolɔjis ɛn fala di tritmɛnt ɛksaktɔli.
- Wit di rayt manejmɛnt, yu kin liv ful, aktif layf wit MG.
💬 Comments (0)
No kɔmɛnt nɔ de yet. Ad yu kɔmɛnt ya fɔ di fɔs tɛm.
Ad yu kɔmɛnt