Yu no bɔt di denja kɔndishɔn fɔ nekrɔtizing pankrias?

Yu dɔn ɛva yɛri bɔt wan siriɔs sik usay wan pat pan di pankrias kin day ? Dis na wetin wi kin kɔl ``Necrotizing Pancreatitis'' pan mɛrɛsin. Imajin aw i siriɔs fɔ lɛ wi lɔs wan pat pan wan impɔtant pat pan wi bɔdi. Dis kin apin we wan sik we dɛn kɔl ``Acute Pancreatitis '' kin rili bad. Tide, wi go tɔk bɔt dis ditayli, lɛk se wi de tɔk to wi padi.

Wetin na di ɛksaktɔli ``(Necrotizing Pancreatitis)``?

Fɔ tɔk am simpul wan, ``Necrotizing Pancreatitis`` na di day we pat pan yu ``Pancreas`` (Necrosis) day. Dis kin apin we di kɔndishɔn ``Pancreatitis`` kin rili bad. Pankrias na we di pankrias swel, rɛd, ɛn pen bikɔs ɔf injuri ɔ sɔntin lɛk pɔyzin. if dis inflameshn rili bad, di bכdi fכ fכlכ to di pankrεas tisu dεm kin disrupt ``Ischemia``. Dɔn dɛn tisu dɛn de nɔ kin gɛt di ɔksijɛn ɛn di tin dɛn we dɛn nid ɛn dɛn kin bigin fɔ day . Dɛn kɔl dis ``Nɛkrɔsis``. Dis na tin we rili denja.

If dis apin, yu mɛdikal tim go kip yu na ɔspitul fɔ sɔm tɛm ɛn wach yu gud gud wan fɔ ɛni ɔda prɔblɛm . Di tin we impɔtant pas ɔl fɔ wach na infekshɔn . Imajin if baktri dɛn bigin fɔ it di tisu we dɔn day, dɛn kin bɔku kwik kwik wan ɛn skata ɔlsay na yu bɔdi. If dat apin, i kin mek pɔsin gɛt siriɔs tin dɛn lɛk we di ɔgan dɛn nɔ wok , we kin mek pɔsin in layf de pan denja. If dɛn kayn tin ya apin, dɔktɔ dɛn kin gɛt fɔ pul di day tisu bay ɔpreshɔn .

Aw dis sik kin kɔmɔn?

fכ tכk roughly, lεk 20% pan di pipul dεm we gεt akyu pankrεas go gεt nεkrotizing pankrεas. Insay kɔntri lɛk Amɛrika, dɛn se na lɛk tri ɔndrɛd tawzin pipul dɛn kin go na ɔspitul ɛvri ia bikɔs ɔf pankrias. So, 20% na signifyant nɔmba, nɔto so?

Wetin na di sayn dɛm fɔ `(Necrotizing Pancreatitis)`?

Di fɔs sayn dɛm wae de sho na di wan dɛm wae gɛt akyu pankrias. Dɛn na:

• Bɔku pen na di ɔp pat na di bɛlɛ. Dis pen kin rayt bak to di bak.
• Abdominal distension ɔ bloating.
• Nɔs ɛn vɔmit.

As pankrias de kam tranga, sɔm kayn sik dɛn lɛk dis kin apin bak:

• Fiva ɛn kol kol.
• Di at rit we de go ɔp (Tachycardia).
• Fɔ tɔsti bad bad wan ɔ we yu nɔ gɛt wata na yu bɔdi.

Wetin na di tin dɛm wae kin mek yu gɛt ``Necrotizing Pancreatitis''?

Dis kin apin insay sɔm stej dɛn. Fɔs, di nɔmal inflamɛns na di pankrias (Acute Pancreatitis) kin bi bad bad wan. Dɔn, di blɔd saplai kin ambɔg (Ischemia), ɛn fɔ dɔn, di tisu dɛn kin day (Necrosis). Difrɛn tin dɛn de we kin mek ɛni wan pan dɛn tin ya apin.

Aw pankrias sik kin rili bad?

Di men tin we kin mek pɔsin gɛt akyu pankrias na di sik we dɛn kɔl galston . dis kin apin we wan gal ston de lod insay di gal blad εn i de blכk di pankrεas dakt. Dɛn kin kɔl dis bak galston pankriaytis . Di sɛkɔn men tin we kin mek pɔsin drink rɔm pasmak .

Inflameshɔn na rili di we aw di bɔdi de ansa we pɔsin wund, fɔ tray fɔ mek di tin we dɔn pwɛl. Bɔt sɔmtɛm dis inflammatory response kin so bad dat i kin bigin fɔ mek damej.

I nɔ klia yet wetin mek dis inflammatory response kin tranga pasmak pan sɔm pipul dɛm pas ɔda pipul dɛm. כltu, i klia se dis de mek `` sno bכl ifekt`` insay di pankrias.

di ay prεshכn we di siriכs inflameshn de kכz de aktibכt pankrεas εnzym dεm insay di pankrεas tisu. nכmal wan, dεn dijestiv εnzym dεm ya de aktibכt afta fכd go insay di dijestiv sistεm. Bɔt if dɛn aktiv dɛn bifo tɛm, dɛn kin bigin fɔ dayjɛst di pankrias insɛf. Imajin, yu de dayjɛst yu yon ɔgan wit yu yon ɛnzaym dɛn!

di rεdכks bכdi saplai de mek i gεt ``Ischemia`` εn tisu dεm de day ``Necrosis``

Dis damej we de go bifo pan di pankrias de mek di pankrias de wɔs. Afta sɔm tɛm, we di pankrias swel kin mek di blɔd vesel dɛn big, ɛn dis kin mek di blɔd we de flɔ to di tisu dɛn nɔ bɔku.

כda tin we kin afekt dis na di Systemic Inflammatory Response Syndrome (SIRS). Dis na wan kɔndishɔn wae de mek pɔrsin gɛt inflamɛns we kin apin ɔlsay na di bɔdi. Dis kin mek di ɔl blɔd prɛshɔn ɛn di blɔd flɔ go dɔŋ.

di bכdi we de fכlכ (ischemia) de mek di tisu dεm day (nεkrכsis). di dijeshכn fכ di pankrias bay di pankrεas εnzym dεm kin kכntribyut bak fכ dis tisu dεm we de day.

Wetin na di poshubul komplikashכn dεm fכ `(Necrotizing Pancreatitis)`?

Dis kכndyushכn kin kam wit difrεn kכmplikεshכn dεm fכ sכt εn lכng tεm.

Sɔm prɔblɛm dɛn we kin apin fɔ shɔt tɛm:

• Infεkshכn: Dis na di risk we de mek yu gεt Necrotizing Pancreatitis. Dis kin apin pan lɛk 20% pan di sik pipul dɛm. Tisu we dɔn day tan lɛk gud ples fɔ it fɔ baktri dɛn we de waka rawnd. I nɔ kin izi fɔ kɔntrol di infekshɔn we yu dɔn ɔlrɛdi sik. If i skata to di blɔd, i kin mek pɔsin in layf de pan denja. Infekshɔn na di blɔd kin mek pɔsin gɛt sɛpsis , we kin mek bɔku ɔgan dɛn nɔ wok . Dis na di men tin wae kin mek pipul dɛm wae gɛt Necrotizing Pancreatitis day.
• di nεkrכtik Fluid kכlekshכn dεm: insay siriכs pankrεas, di pankrεas εnzym dεm we dεn aktibכt kin lik kכmכt na di pankrεas εn pwεl di tisu dεm we de rawnd. wan kapsul we de fכm tכn tisu de fכm rawnd di pankrεas fכluid. If dis kapsul gεt dεd tisu εn baktri dεm, infεkshכn kin izi fכ stat εn spre. Na smɔl tɛm nɔmɔ dis kapsul kin big ɛn prɛs pan di ɔgan dɛn we de nia am, lɛk di bɛlɛ, di blɔd vesel dɛn, ɔ di bayl dakt dɛn.
• Ɛmoraji: Ɛmoraji pankrias nɔ kin bɔku, bɔt i kin mek pɔsin in layf de pan denja if i apin. Necrotizing pancreatitis de mek di risk fɔ dis blɔd de bɔku. Wan we we dis kin apin na if di inflamɛns ɔ wata we de na di pankrias go skata to wan at we de nia de, we go pwɛl di at in wɔl ɛn mek blɔd kɔmɔt. Wan ɔda we na if di pankrias ɛnzaym dɛn brok wan at in wɔl, ɛn mek wan pseudoaneurysm , we kin brok ɛn mek blɔd kɔmɔt.
• Abdominal Compartment Syndrome: We yu de swel, blɔd de kɔmɔt, ɛn ɔda wata we de gɛda we gɛt fɔ du wit necrotizing pancreatitis kin mek yu gɛt ay prɛshɔn insay di bɛlɛ. Dɛn kin si dis mɔ pan pipul dɛn we sik bad bad wan. Dis kin mek di blɔd nɔ de go na di ɔgan dɛn, we kin mek di blɔd klɔt , ischemia, ɛn hypoxia . Dis kin mek bak bɔku ɔgan dɛn nɔ wok fayn.

Di bad tin dɛn we kin apin fɔ lɔng tɛm:

• Pankrias Insufficiency: If bɔku pankrias tisu lɔs, sɔm pan di pankrias in wok kin lɔs. Exocrine Pancreatic Insufficiency na we di pankrias nכ de prodyuz inof εnzym dεm fכ daygεst it. Dis kin mek i nɔ gɛt bɛtɛ tin fɔ it ɛn i nɔ kin it fayn . εndocrine Pancreatic Insufficiency na we di pankrias nכ de prodyuz inof כmon dεm we de kכntro di bכdi shuga lεvεl. Dis kin mek yu gɛt aypa glycemia ɛn dayabitis .
• Disconnected Pancreatic Duct Syndrome: We yu de swel bad bad wan, blɔd de kɔmɔt, di tisu dɛn we de day, ɛn ɔda prɔblɛm dɛn we kin kam wit nekrotizing pancreatitis kin mek di pankrias dakt nɔ kɔmɔt na di pankrias ɔ di smɔl intestin. dis kin mek di pankrεas εnzym dεm kכntinyu fכ lik. dis lik kin mek di wata we de kכmכt fכ lכng tεm εn/כ pankrεas we de te.
• Bilari Strikchɔ: .siriכs εn lכng tεm inflameshn kin mek ska na eni wan pan di dakt dεm we de kכnekt di pankrias to di dijestiv sistεm (pankrias dakt, bayl dakt, duodenum - di biginin fכ di sכmכl intestin). dis ska de mek di dakt de sכmtεm abnכmal wan (strikt). dis de mek di bayl fכ fכlכ slo, εn di bayl de bigin fכ bak insay di biliary sistεm.
• Splanchnic Vein Thrombosis: Yu splanchnic vein dεm de כnda yu pankrias. Siriɔs pankrias kin mek dɛn gɛt inflamɛns. dis kin mek bכdi kכlכt (thrombosis) na dεn vein dεm ya. dis vein dεm inklud di spεlin vein, di mεsεntrik vein, di εpatik vein, εn di pכtal vein. If blɔd klɔt fɔm na wan pan dɛn, difrɛn prɔblɛm dɛn kin apin, lɛk pɔtal haypatɛnshɔn , vays na di bɛlɛ, blɔd we de kɔmɔt na di bɛlɛ, ischemic colitis, ɛn mesenteric ischemia.

Aw dɛn kin no se pɔsin gɛt Necrotizing Pancreatitis?

di dכkta dεm kin no dis kכndyushכn `(Necrotizing Pancreatitis)` afta dεn fכs no se `(Acute Pancreatitis).` Di klia sayn dεm fכ di tisu dεm we de day `(Necrosis)` nכ de apin te tri to fayv dez afta di pankrεatitis bigin. If yu gɛt sayn dɛm fɔ siriɔs pankriaytis sɔm dez afta di fɔs inflamɛns, yu dɔktɔ go yuz CT skan wit fluorescent day `(Contrast-enhanced CT scan)` ɔ MRI.` (MRI - Magnetic Resonance Imaging)` fɔ luk fɔ dis tisu day. Dɛn go luk bak fɔ ɔda prɔblɛm dɛn lɛk we wata kin gɛda.

Wetin na di tritmɛnt dɛm fɔ dis?

Yu tritmɛnt go dipen pan if yu gɛt infekshɔn ɔ ɔda prɔblɛm dɛn. If pankrias nɛkrɔsis nɔ gɛt wan sik ɛn nɔ gɛt ɛni sayn, bɔku tɛm dɔktɔ dɛn go trit am wit sɔpɔt kia . If sayn dɛm fɔ infekshɔn ɔ ɔda prɔblɛm dɛn kam, dɔktɔ dɛn go ɛp am as nid de. Dɛn go tray fɔ pul di tisu we dɔn day bay we dɛn de yuz di we dɛn we nɔ go ambɔg di bɔdi bifo dɛn du ɔpreshɔn.

Kɔnsɔvativ Manejmɛnt

Sɔpɔtiv kia fɔ nɔ-infɛkshɔn ``Sterile Necrotizing Pancreatitis`` inklud:

• Di tin dɛn we dɛn kin yuz fɔ mek pɔsin fil pen.
• Fluid dɛn we dɛn kin put insay di bɛlɛ `(IV Fluids)`.
• Ɛntɛral Nutrishɔn.

Bɔrku pan di kes dɛm wae nɔr kɔmplikt go sɔlv wit sɔpɔtiv kia nɔmɔ. Insay dis tɛm, yu mɛdikal tim go wach yu sik gud gud wan. Dɛn go wach yu vital sayn dɛm , yu bɛlɛ prɛshɔn, ɛn kɔmplit blɔd kɔnt.Dɛn go wach tin dɛn lɛk di Kɔmplit Blɔd Sɛl Kɔnt (CBC) ɛn wach fɔ di prɔblɛm dɛn we kin apin. If sɔntin lɛk infɛkshɔn ɔ ɔgan we nɔ de wok fayn apin, dɛn go gi layf sɔpɔt ɔ ɔda tin dɛn we dɛn nid.

Drenaj ɛn Debridmɛnt

As yu bigin fɔ si sayn dɛn fɔ se yu gɛt di sik so, yu mɛdikal tim go bigin yu fɔ tek antibayɔtik ɛn plan fɔ pul ɛni tisu we dɔn day if i pɔsibul. Dɛn go bigin wit di we we nɔ pas ɔl, dɔn dɛn go inkrisayz di intensiti smɔl smɔl if nid de.

Dɛn we ya na:

• Pɛrkyutanɛs drenaj: Pɛkyutanɛs min tru di skin. Wan intavɛnshɔnal raydiɔlɔjis kin yuz imej tɛknik (bɔku tɛm na ɔltra saund ɔ CT skan) fɔ fɛn di say we di tisu dɔn day ɛn i kin put wan tiub tru yu skin. Dɛn kin lɛf di tiub na in ples ɛn was am wit salin bɔku tɛm insay di de fɔ mek di wata kɔmɔt. Dis na di wangren tin we dɛn kin du fɔ lɛk wan pat pan tri pan di sik pipul dɛn. Fɔ ɔda pipul dɛn, i kin ɛp fɔ kɔntrol di infɛkshɔn te dɛn ebul fɔ du ɔda we dɛn fɔ pul di bɔdi sef wan.
• Endoscopic Debridement: Na wan we we dɛn kɔl ɛndoskopi de mek di dɔktɔ we de mɛn di bɛlɛ kin rich to di day tisu we de insay yu bɔdi we i nɔ kɔt yu skin. I go pas wan ɛndoskɔp, we gɛt ɔltra saund prob, tru yu ɔpa gastrointestinal trakt fɔ fɛn di say we di pankrias de. afta dat, dεn de pas instrכmεnt dεm tru di εndoskop fכ mek wan chanεl bitwin di dεd tisu εn yu gεstrointestinal trakt. Dɛn kin pul di tisu we dɔn day tru da chanɛl de.
• Vidio-assisted Retroperitoneal Debridement (VARD): Dis na ɔspitul we nɔ kin tek bɔku tin bak. Dis involv fɔ put ɔspitul inschrumɛnt dɛn tru di sem say we yu dɔn ɔlrɛdi gɛt na yu skin we dɛn kɔl Pɛkyuta Drenaj Pɔtal ɛn go na di say we di day tisu de. Wan ɔspitul de yuz fɔspɛs, irigashɔn ɛn sɔkshɔn fɔ pul di day tisu tru di say we dɛn kɔt am. If nid de, dɛn kin mek di say we dɛn kɔt am big ɛn put wan tiub we gɛt kamɛra we dɛn kɔl laparoskop. Dɔn dɛn kin pul di tisu we lɛf bay we dɛn de yuz wan laparoskopik we dɛn kɔl laparoskopik ɔpreshɔn.
• Open Surgery - Necrosectomy: Nεkrosεktכmi na we dεn de pul di dεd tisu. opin ɔpreshɔn involv fɔ opin di bɛlɛ ɛn fɛn di day tisu (Laparotomy). Dis stil na di kwik we fɔ fɛn ɛn trit di prɔblɛm dɛn we kin apin we pɔsin gɛt prɔblɛm. Pan ɔl we ɔpreshɔn kin gɛt sɔm prɔblɛm dɛn, na di las tin we dɛn kin du fɔ ɛnitɛm ɛn we di we dɛn we nɔ kin tek bɔku tɛm nɔ wok.

Wetin na di mכtalman rεt εn rεkכvεshכn rεt fכ `(Necrotizing Pancreatitis)`?

Di chans fɔ mek yu wɛl de dipen pan aw bɔku pan yu pankrias dɔn day, if yu gɛt infɛkshɔn ɔ yu ɔgan dɛn we nɔ de wok fayn, ɛn aw yu de du wɛl to tritmɛnt. If i nɔ rich 30% pan yu pankrias, di pipul dɛn we de day nɔ go rich 15% . If na tisu nɔmɔ de day we nɔ gɛt infɛkshɔn, dat fayn. Bɔt if pas 50% pan yu pankrias afɛkt, ɛn yu gɛt infɛkshɔn ɔ yu ɔgan dɛn we nɔ de wok fayn, di pipul dɛn we de day go go ɔp to pas 30% .

Nɔ mek yu fred wit dɛn statystik ya. Dis na jɔs jɔnaral infɔmeshɔn. Na di mɛdikal tim nɔmɔ we de trit yu go ebul fɔ tɛl yu fayn fayn wan bɔt yu sik ɛn yu chans fɔ wɛl.

Wetin kin apin afta dɛn dɔn trit am?

Na yu fɔlɔp apɔntinmɛnt afta tritmɛnt, yu dɔktɔ go aks yu bɔt ɛni sik we de go bifo ɔr nyu. Necrotizing Pancreatitis kin gɛt lɔng tɛm kɔmplikeshɔn ivin afta dɛn dɔn trit am. If yu gɛt sɔm sayn dɛm, dɛn kin aks yu fɔ du blɔd tɛst, lab tɛst, ɔr imej tɛst fɔ chɛk fɔ dɛn. Di prɔblɛm dɛn kin nid fɔ gɛt ɔda tritmɛnt, we kin bi fɔ shɔt tɛm ɔ fɔ lɔng tɛm.

Necrotizing pancreatitis na wan rili siriɔs kɔmplikeshɔn fɔ akyu pankrias. Pan ɔl we bɔku pipul dɛn kin wɛl frɔm akyu pankrias wit sɔpɔtiv kia nɔmɔ, di wan dɛn we kin gɛt siriɔs pankrias ɛn nɛkrɔsis nid fɔ gɛt lɔng tɛm, intensiv kia. Yu go nid wan tim we gɛt bɔku bɔku dɔktɔ dɛn fɔ wach yu kɔndishɔn ɛn ɛni prɔblɛm we go apin. Yu kin nid fɔ gɛt intavɛnshɔn ɔ ɔpreshɔn, ɛn sɔntɛm fɔ kia fɔ yu fɔ fala yu.

Di impɔtant tin dɛn we wi nid fɔ mɛmba frɔm dis stori (Take-Home Message) .

• Necrotizing Pancreatitis na siriɔs sik we wan pat pan di pankrias kin day.
• Bɔku tɛm, dis kin apin bikɔs ɔf siriɔs akyu pankrias. Di men tin dɛn we kin mek pɔsin gɛt ston na gal ston ɛn fɔ drink rɔm pasmak .
• If yu gɛt sɔm sayn dɛn lɛk bad bad bɛlɛ pen, fiva, nɔs, ɛn vɔmit, go to dɔktɔ wantɛm wantɛm.
• Infεkshכ n na di men εn denja kכmplikεshכn fכ dis kכndyushכn.
• Di tritmɛnt we dɛn kin pik kin difrɛn fɔ di pɔsin in kɔndishɔn. Difrɛn tritmɛnt dɛn de , frɔm sɔpɔt kia to ɔpreshɔn .
• Pan ɔl we dis na siriɔs sik, bɔku pipul dɛn kin wɛl if dɛn gɛt di rayt tritmɛnt ɛn kia fɔ dɛn , so nɔr giv ɔp.

If yu ɔ pɔsin we yu sabi gɛt ɛni wan pan dɛn sik ya, duya go to dɔktɔ wantɛm wantɛm. If yu trit am kwik, dat kin sev pipul dɛn layf!

` Necrotizing Pancreatitis, Pancreatitis, Pankreas day, Bɛlɛ at, Pankreas infɛkshɔn, Pankreas Sinhala, Pankreas sik dɛn