Yu de lɔs yu balans bak we yu de waka ɛn i nɔ izi fɔ yu fɔ muv yu yay? I kin bi PSP (Progresiv Supranyuklia Palsi)!

Yu kin si se yu nɔ de balans ɛn fɔdɔm ɛvri tɛm we yu de waka? Ɔ i nɔ kin izi fɔ yu fɔ kɔntrol yu yay we yu de tray fɔ luk dɔŋ? Sɔntɛm yu dɔn si pɔsin we yu sabi gɛt dis prɔblɛm. Dis kin bi sɔm pan de fɔs sayn dɛm fɔ wan sik wae nɔr kin bɔrku wae dɛn kɔl PSP, ɔr Progressive Supranuclear Palsy, wae wi go tɔk bɔt tide. Nɔ wɔri, wi go tɔk bɔt dis ditayli.

Wetin na PSP (Progresiv Supranyukliar Palsi)? Lɛ wi ɔndastand am simpul wan!

Okay, naw lɛ wi si wetin dis sik wit di rather long nem PSP (Progressive Supranuclear Palsy) bi. Fɔ tɔk am simpul wan, na wan sik we de go bifo pan nyurolɔjik we de pwɛl sɔm pat dɛn na wi bren. E kin afɛkt tin lɛk aw yu de waka, aw yu de tink, aw yu de swɛla, ɛn aw yu de muv yu yay. I gɛt ɔda nem dɛn bak, lɛk di sik we dɛn kɔl Steele-Richardson-Olszewski syndrome.

Naw luk, i izi if yu ɔndastand sɔm pan di wɔd dɛn we de insay di nem.

• "Progressive" min, lɛk aw a bin dɔn tɔk bifo, se dɛn sik ya kin wɔs smɔl smɔl as tɛm de go. di rizin fכ dis na we di bren sεl dεm de wik sכmtεm (wan nyurodijεnεraytiv kכndishכn).
• di wכd dεm "Supranuclear" εn "Palsy" dεn kin kam togεda fכ dεskrεb wan kכndyushכn we de afekt di muvmεnt fכ di yay dεm. "Supranuclear" min se di damej de oba di nyuklios dεm na di bren we de kכntro di yay muvmεnt. "Palsy" min se di mכsul dεm wik כ i kin at fכ yuz dεm.

Mɛmba se sɔmtɛm dɛn kin kɔnfyus PSP wit di sik we dɛn kɔl Pakinsin, mɔ we di sik bigin. Dɔktɔ dɛn kɔl dis "atypical parkinsonian syndrome" ɔ "Parkinson-plus disorder." Dis min se pan ɔl we i gɛt sayn dɛn we fiba di sik we dɛn kɔl Pakinsin, na difrɛn, mɔ kɔmpleks sik. Bɔt mɛmba se PSP kin go bifo kwik kwik wan pas di sik we dɛn kɔl Pakinsin.

Dis sik kin kam pan pipul dɛm wae dɔn pas 60. I nɔr kin izi fɔ pɔrsin wae nɔr rich 40 ia fɔ gɛt am.

Wetin na di men kayn PSP (Progressive Supranuclear Palsy)?

fכ men tכp dεm, כ fεnotayp dεm de fכ PSP. Pan ɔl we ɔl dɛn kayn tin ya gɛt kɔmɔn sayn, sɔm difrɛns dɛn de we nɔ klia. Di tu kayn dɛn we dɛn kin yuz mɔ na:

1. Wan sik we dɛn kɔl Richardson syndrome

2. Pakinsin sik lεk vεryכnt (PD-lεk vεryכnt - PSP-P) .

Dɛn tu kayn ya de ripresent lɛk 75% pan di PSP pasɛnt dɛn.

Pɔrsin wae gɛt Richardson syndrome kin gɛt bɔrku pan dɛn kayn sik ya:

• Prɔblɛm dɛn we pɔsin kin gɛt we i de waka ɛn balans.
• Abnɔmal tin dɛn we yu de tɔk (we yu nɔ de tɔk fayn, yu vɔys de chenj).
• Prɔblɛm wit mɛmori ɛn ebul fɔ tink.
• I nɔ kin izi fɔ kɔntrol di we aw yu yay de muv (espɛshali we yu de luk dɔŋ).
• Wan fes we yu de sho lɛk se yu de luk am stret wit yu yay we big.

Pipul wae gɛt dis sik wae tan lɛk Pakinsin sik (PSP-P) kin gɛt sɔm kayn sik wae de mɛk pɔrsin gɛt dis sik, bɔt dɛn kin fiba mɔr lɛk Pakinson sik. di men simptom na trem (we de shek we di mכsul dεm de kכntrikshכn we i nכ want). Tremכr kin bכku pas bεlε prכblεm εn bihayvya chenj. PSP-P de ansa mɔ to antiparkinsonian mɛrɛsin pas ɔda kayn PSP.

Di ɔda tu kayn dɛn we nɔ kin bɔku na:

• Kɔtikobasal sindrom.
• Pure akinesia ɛn gait friz (difikulti fɔ muv ɛn friz we yu de waka).

PSP (Progressive Supranuclear Palsy) na sik we pipul dɛn kin gɛt?

Nɔ, PSP na wan kɔndishɔn we nɔ kin apin so ɔltɛm. Dɛn se na lɛk fayv pan ɛvri ɔndrɛd tawzin pipul dɛn nɔmɔ gɛt dis sik. Na wan pan ɛvri ɔndrɛd tawzin pipul dɛn nɔmɔ kin gɛt dis sik ɛvri ia. So yu kin si aw dis nɔ kin apin so ɔltɛm.

Wetin na di sayn dɛm fɔ PSP (Progressive Supranuclear Palsy)?

Di sayn dɛm fɔ PSP kin difrɛn frɔm wan pɔrsin to ɔda pɔrsin. Dɛn kin bigin smɔl smɔl ɛn smɔl smɔl dɛn kin wɔs as di ia dɛn de go.

De fɔs sayn wae kin kam pan pɔrsin kin bi:

• Nɔ balans we yu de waka ɔ klaym stej. Dis kin mek pɔsin fɔdɔm bɔku tɛm, mɔ we i de bak.
• I nɔ izi fɔ luk dɔŋ wit di yay.
• Wan fes we yu de sho lɛk se yu de luk am stret wit yu yay we big.

Ɔda sayn dɛm wae yu kin si na:

• I nɔ kin izi fɔ swɛla it ɛn drink.
• di mכsul dεm stiff de mek i at fכ muv di bכdi (mobility).
• I nɔ izi fɔ tɔk. Di vɔys kin slo ɛn slɔp. I kin at bak fɔ kɔl wɔd dɛn.
• Mud chenj: pwɛl hat, nɔr bisin bɔt ɔda pipul dɛm, wae pɔrsin kin vɛks.
• Di pɔsin we i bi kin chenj.
• Di chenj na di we aw pɔsin de biev: i de du tin we i nɔ de tek tɛm, we i nɔ ebul fɔ pik wetin rayt frɔm wetin rɔŋ.
• Dimɛnshɔn (we de mɛmori ɛn intɛlijɛns de go dɔŋ smɔl smɔl).
• Nɔ ebul slip.
• REM slip bihayvya dizayd (RBD) (we yu de kray ɛn flay na yu an ɛn fut dɛn we yu de drim).
• Sεnsitiviti to brayt layt (fotophobia).

Wetin kin mek pɔsin gɛt PSP (Progressive Supranuclear Palsy)?

Sayɛnsman dɛn stil nɔ no bɛtɛ bɛtɛ wan wetin kin mek pɔsin gɛt PSP. Bɔt,dεn fכnshכn se wan protin we dεn kכl "tau" de involv insay dis. Tau na wan prɔtin we rili impɔtant fɔ di wɛlbɔdi na wi bren. na dis protin de protεkt di nכmal strכkchכ fכ di bren sεl dεm (nyuron dεm).

if yu gεt PSP, dεn tau protin dεm ya na yu bren de kכlכp tכgeda εn fכm agregεt. dεn kכlכmp dεm fכ tau protin dεm de dכn pwεl di bren sεl dεm. Risach pipul dɛn tɔk bɔt sɔm rizin dɛn we kin mek dis apin:

• Random jenɛtik muteshɔn dɛn.
• Di tin dɛn we dɛn nɔ no bɔt we kin mek pɔsin gɛt di sik.
• Wan kemikal we wi nɔ no we de na wi envayrɔmɛnt (ɛya, wata, it) we de pwɛl sɔm sɛnsitiv pat dɛn na di bren smɔl smɔl.

PSP nɔ de afɛkt ɔlman di sem we. I kin afɛkt difrɛn pat dɛm na di bren na difrɛn stej dɛm na di sik, to difrɛn digri dɛm. Afta sɔm tɛm, PSP kin skata to bɔku pan di bren. insay di fכs stej dεm, di kכndyushכn kin afekt di basal ganglia εn di bren stεm mכst.

Yu bren stem de du bɔku impɔtant wok dɛn lɛk fɔ swɛla ɛn fɔ tinap. Di basal ganglia de ɛp yu bak fɔ kɔntinyu fɔ tinap, muv yu yay, tink, ɛn kɔntrol aw yu de fil.

PSP (Progressive Supranuclear Palsy) na frɔm in mama ɛn papa?

Nɔ, PSP rili rare. If yu gɛt PSP, di risk fɔ mek ɔda pipul dɛn na yu famili, inklud yu brɔda ɛn sista ɛn pikin dɛn, gɛt am rili smɔl. So natin nɔ de fɔ wɔri bɔt.

Wetin na di risk factor dɛm fɔ mek yu gɛt PSP (Progressive Supranuclear Palsy)?

Di men risk factor fɔ divɛlɔp PSP na di ej. Yu risk fɔ gɛt PSP kin bɔku we yu ol 60 ia ɔ pas dat. Dis sik kin bɔrku smɔl pan man dɛm pas uman dɛm.

Wetin na di kɔmplikɛshɔn dɛm wae de kam wit PSP (Progressive Supranuclear Palsy)?

As PSP de go bifo, di sik pipul dεm kin lכs kכntro pan di mכsul dεm na dεn mכt, trot, εn tכng.

If yu nɔ ebul fɔ kɔntrol di mɔsul dɛn na yu trot, dat kin mek i nɔ izi fɔ swɛla it ɛn drink. Dis kin mek dɛn nid fɔ gɛt fidin tyub fɔ mek it nɔ stɔp ɛn infɛkshɔn na in chɛst.

Bɔrku pipul dɛm wae gɛt PSP kin gɛt prɔblɛm bak wit aw dɛn bɔdi ɛn blad de wok. Fɔ ɛgzampul:

• Banbɛlɛ.
• I nɔ kin izi fɔ yu fɔ pis.
• Fɔ pis bɔku tɛm na nɛt.
• yu bכwel we yu nכ de muv (bכwel inkontinεns).
• Urinary incontinence.

Aw dɛn kin no se pɔsin gɛt PSP (Progressive Supranuclear Palsy)?

PSP kin tranga smɔl fɔ dɔktɔ dɛn fɔ no di sik kɔrɛkt wan. As a bin dɔn tɔk bifo tɛm, dɛn kin kɔnfyus am wit Pakinsin sik, mɔ we i de bigin.Naw, no patikyula tɛst nɔ de we go ebul fɔ no PSP. Bɔku tɛm, dɔktɔ dɛn kin no di sik bay di sayn dɛn we yu gɛt ɛn di tɛst dɛn we dɛn kin du fɔ tek pikchɔ dɛn na yu bren.

If yu dɔktɔ tink se yu gɛt PSP, i go mɔs ɔda fɔ mek dɛn du MRI (magnetic resonance imaging) skan fɔ yu bren . Dis kin mek yu nɔr gɛt ɔda tin dɛm wae kin de mek yu gɛt dis sik, lɛk Pakinsin sik ɔr strok. כlso, if di MRI sho shrinkage na di midbren, i de inkrεs di chans fכ yu gεt PSP.

Fɔ no dis sik kɔrɛkt wan, yu go mɔs nid fɔ go to nyurolɔjis we spɛshal pan Pakinsin sik ɛn di prɔblɛm dɛn we kin mek yu muv.

Pan ɔl we bɔku sayn dɛn de fɔ PSP, di men sayn we de kɔnfirm di sik na we i nɔ izi fɔ muv di yay ɔp ɛn dɔŋ. Ɔda sayn dɛn we kin apin na we pɔsin kin fɔdɔm ɔltɛm ɛn i nɔ kin izi fɔ swɛla.

Wetin na di tritmɛnt dɛm fɔ PSP (Progressive Supranuclear Palsy)?

I sɔri fɔ no se naw, no mɛrɛsin ɔ tritmɛnt nɔ de fɔ PSP. Bɔt sɔm tritmɛnt dɛn de we go ɛp fɔ kɔntrol yu sik dɛn ɛn mek yu layf bɛtɛ.

Di tritmɛnt dɛn we yu kin gɛt na:

• Di mɛrɛsin dɛn we dɛn kin tek bay mɔt.
• Muvmɛnt tritmɛnt dɛn.
• Di tritmɛnt dɛn we dɛn kin du fɔ mek dɛn yay.
• pεrkyuta εndoskopik gastrostomi (PEG) - fכ it tru wan tכb we dεn put insay di bεlε.
• Palliative kia fɔ yu.

I kin bi bak se klinik trial fɔ PSP we yu kin tek pat pan Aks yu mɛdikal tim bɔt dɛn tin ya.

Di mɛrɛsin dɛn we dɛn kin tek bay mɔt

Sɔntɛnde, antiparkinsonian mɛrɛsin kin ɛp fɔ kɔntrol di sayn dɛm fɔ PSP. Dɛn kin ɛp fɔ sɔm tɛm fɔ lɛ yu nɔr gɛt sɔm kayn sik lɛk wae yu de balans prɔblɛm, yu mɔsul dɛn de stif, yu de muv sloslo, ɛn yu de shek. Bɔt, dɛn nɔ de wok di sem we fɔ ɔlman. Di mɛrɛsin dɛn we dɛn kin yuz mɔ fɔ PSP na:

• Levodopa (e.g. Atamet®, Rytary®, Sinemet®).
• Levodopa wit anticholinergic ejen dɛn.
• Amantadin (e.g. Simɛtrel®) we dɛn kin yuz.

Dɛn kin yuse mɛrɛsin wae de mek pɔrsin fil bad fɔ trit klinik pwɛl hat sik. Dɔktɔ dɛn kin gi yu dɛn tin ya fɔ ɛp yu fɔ bia wit di mental wɛlbɔdi prɔblɛm dɛn we PSP kin kam wit. De mɛrɛsin wae dɛn kin gi pasmak fɔ mek pɔrsin fil bad na:

• Fluoxetine (e.g. Prozac®) we dɛn kɔl Prozac®.
• Amitriptilin (e.g. Ɛlavil®).
• Imipramin (fɔ ɛgzampul, Tofranil®).

Saykotɛrapi (tɔk tritmɛnt) na fayn we bak fɔ ɛp wit mɛntɛl hεlth prɔblɛm ɛn liv wit de sik.

Muvmɛnt tritmɛnt dɛn

Dɛn tritmɛnt ya kin ɛp fɔ pul sɔm pan di sayn dɛm fɔ PSP:

• Fizik tritmɛnt: Fizik tritmɛnt kin ɛp fɔ kɔntrol tin dɛm lɛk pen, stiffness, ɛn prɔblɛm fɔ muv arawnd.
• Ɔkupeshɔn tɛrapi: Ɔkupeshɔn tɛrapist na pɔsin we de ɛp yu fɔ mek yu ebul fɔ du wok dɛn we yu de du ɛvride. Dɛn kin tich yu aw fɔ tinap, sidɔm, muv, ɔ yuz difrɛn tin dɛn fɔ du yu wok sef wan.
• Spich therapy: Speech terapist dεm de εp pipul dεm fכ win di prεblεm fכ tכk εn swεl.

Di tritmɛnt dɛn we dɛn kin du fɔ mek dɛn yay

Dɛn tritmɛnt ya kin ɛp fɔ gɛt difrɛn ay prɔblɛm dɛn:

• Botox® (botulinum toxin) injɛkshɔn: If i nɔ izi fɔ yu fɔ kɔntrol yu yaylid, Botox injɛkshɔn kin rilaks di mɔsul dɛn na yu yaylid fɔ sɔm tɛm.
• Ay drɔp ɛn atifishal kray wata: Dɛn tin ya kin ɛp fɔ wet yu yay if yu yay dray bikɔs di ay lɔbrikɛshɔn dɔn go dɔŋ.
• Speshal glas: Speshal glas wit prism lens de ɛp yu fɔ si tin dɛn we de dɔŋ yu layn fɔ si.
• Glas we yu kin rap: If yu kin fil fayn to brayt layt, we yu wɛr dak glas we de rap rawnd yu yay lɛk sanglas, dat kin mek yu fil fayn.

Pɛrkyutan Ɛndoskɔpik Gastrostomi (PEG) .

We PSP tranga, yu kin rich wan say we yu nɔ go ebul fɔ swɛla ɛni it ɔ drink. Dis min se yu nɔ go ebul fɔ it ɔ drink. Bifo yu rich da say de, yu dɔktɔ kin tɛl yu fɔ du percutaneous endoscopic gastrostomy (PEG) .

Fɔ tɔk am simpul wan, PEG na wan we we dɔktɔ we de du ɔpreshɔn kin put wan tiub tru yu bɛlɛ insay yu bɛlɛ. Yu it, mɛrɛsin, ɛn wata we de kɔmɔt na yu bɔdi kin go insay yu bɔdi tru dis tiub.

Paliativ kia we dɛn kin kia fɔ

Palliative care na spɛshal kayn kia wae de gi sɔm kayn sik, kɔmfɔt, ɛn sɔpɔt pipul dɛm wae de liv wit siriɔs sik lɛk PSP. I nɔ de sɔpɔt di pɔsin nɔmɔ, bɔt i de sɔpɔt bak di wan dɛn we de kia fɔ dɛn ɛn in famili.

Dis kia na apat frɔm di tritmɛnt we yu kin gɛt frɔm yu dɔktɔ fɔ ɛp yu fɔ manej yu PSP. Palliative care de gi yu di mɛdikal, soshal, ɛn saykolojik sɔpɔt we yu nid fɔ liv fayn fayn wan ɛn fɔ bia wit siriɔs sik.

Wetin na di prɔgnosis fɔ PSP (Progressive Supranuclear Palsy)? (Prɔgnosis) .

di prognosis fכ PSP jεnarali pwεl. Di simptom dɛn kin wɔs as tɛm de go, ɛn naw nɔr gɛt mɛrɛsin fɔ rivɛns ɔ stɔp PSP. Bɔt, di kwik we dɛn no se yu gɛt di sik ɛn bigin fɔ plan fɔ trit yu, na di mɔ yu layf go bɛtɛ.

Bɔrku pipul dɛm wae gɛt PSP kin dɔn nid wilchia. Dɛn kin nid fɔ kia fɔ dɛn fɔ sɔm tɛm ɔ ful-taym insay tri to 4 ia afta dɛn gɛt di sik. Bɔt dis kin difrɛn frɔm wan pɔsin to ɔda pɔsin. As tɛm de go, di kɔmplikeshɔn dɛn we de kɔmɔt frɔm PSP kin bi layf pan denja.

Wetin na di layf we pɔsin we gɛt PSP (Progressive Supranuclear Palsy) kin liv?

Pipul wae gɛt PSP kin liv fɔ siks to nayn ia afta dɛn dɔn no bɔt dis sik, bɔt dis kin difrɛn.

PSP simptom dεm de inkrεs di risk fכ gεt nyumonia, we kin kil. Di tin wae kin mek pipul dɛm wae gɛt PSP day na aspireshɔn nyumonia. dis na we it εn drink kin kכmכt na di lכng dεm aksidεntli tru di winda paip biכs di trot mכsul dεm wik εn nכ de kכdכnayt fayn.

Pipul wae gɛt PSP kin gɛt bɔrku risk fɔ fɔdɔm bak. We pɔsin fɔdɔm, i kin mek in bon brok ɛn in ed kin wund. Fɔdɔm we kin mek pɔsin gɛt siriɔs injury na tin bak we kin mek pipul dɛn we gɛt PSP day.

Yu tink se dɛn kin mek dɛn nɔ gɛt PSP (Progressive Supranuclear Palsy)?

Bikɔs di wan dɛn we de du risach stil nɔ no bɛtɛ bɛtɛ wan wetin kin mek pɔsin gɛt PSP, naw, no we nɔ de fɔ mek i nɔ apin.

Ustɛm a fɔ go to dɔktɔ?

Yu go nid fɔ si yu mɛdikal tim ɔltɛm fɔ wach aw yu sik de go bifo ɛn fɔ mek shɔ se yu tritmɛnt plan de wok fayn fayn wan.

If yu gɛt ɛni sayn we de wɔri yu, kɔl yu dɔktɔ wantɛm wantɛm.

Fɔ no se yu gɛt PSP (Progressive Supranuclear Palsy) kin tranga fɔ bia wit am. Yu mɛdikal tim go ɛp yu fɔ mek yu yon plan fɔ mɛn di sik dɛn. Di tin we impɔtant pas ɔl na fɔ mek shɔ se yu gɛt di sɔpɔt we yu nid ɛn de pe atɛnshɔn pan yu wɛlbɔdi biznɛs. Mɛmba se yu mɛdikal tim de ɔltɛm fɔ sɔpɔt yu ɛn yu famili.

Fɔ dɔn, di tin dɛn we impɔtant pas ɔl we wi fɔ mɛmba

PSP na kɔmpleks ɛn rare kɔndishɔn. Bɔt, i impɔtant fɔ no bɔt am, no di sayn dɛn kwik kwik wan, ɛn go to dɔktɔ ɛn tritmɛnt fɔ di rayt we.

• No bɔt de sik wae de kam kwik: Wach fɔ tin dɛm lɛk wae yu nɔr kin ebul fɔ waka, yu nɔr kin ebul fɔ balans, ɛn yu nɔr kin ebul fɔ luk dɔŋ.
• Go to dɔktɔ fɔ advays: If yu gɛt dawt, go to dɔktɔ we de mɛn yu nyuro fɔ mek dɛn chɛk yu.
• Kɔntinyu fɔ trit am: Pan ɔl we dɛn nɔ go ebul fɔ mɛn di sik, tritmɛnt dɛn de fɔ kɔntrol di sayn dɛm ɛn fɔ mek yu liv bɛtɛ layf.
• Tink bɔt yu maynd wɛl bɔdi: E fayn fɔ mek yu gɛt strɔng maynd wae yu de liv wit dis kayn sik. Go to advays if nid de.
• Yu fɔ no bɔt sɔpɔt savis dɛm: Fizik tritmɛnt, wok tɛrapi, tɔk tɛrapi, ɛn palliativ kia kin ɛp yu bak.

A op se dis infɔmeshɔn go ɛp yu. If yu ɔ pɔsin we yu lɛk de gɛt dis prɔblɛm, nɔ sɔfa yu wan. If yu gɛt di rayt mɛrɛsin ɛn di wan dɛn we yu lɛk de kia fɔ yu, yu go ebul fɔ bia wit dis prɔblɛm.

` PSP, Progresiv Supranyukliar Palsi, Bren Disiz, Nyurolכjik Disiz, Pakinsin, Muvmεnt Dizכrd, Balεns