Yu kɔlon inflam lɛk dis? Lɛ wi lan bɔt Pseudomembranous Colitis!

Yu kin gɛt siriɔs bɛlɛ pen ɛn dayarɛa bɔku tɛm insay di de? Sɔntɛm yu kin fil bak wit nɔys wit fiva? Ɛspɛshali, dɛn sayn ya bin apin afta yu jɔs tek antibayɔtik fɔ sɔm sik? If na so i bi, dis na sɔntin we go impɔtant to yu. Tide wi go tɔk bɔt wan sik we dɛn kɔl ‘Pseudomembranous Colitis’. Nɔ wɔri, if dɛn tɛl yu fayn fayn wan bɔt dis, yu kin gɛt tritmɛnt ɛn wɛl kwik kwik wan.

Wetin na Pseudomembranous Colitis?

Fɔ tɔk am simpul wan, ‘Pseudomembranous Colitis’ na wan bad bad inflammatory kɔndishɔn we kin apin na wi big intestinal, ɔ kɔlon. insay dis, fכ sכm rizin (i kin bi baktri, tכxin, כ כda sik), di insay wכl na yu big intestin, כ di mכkus mεmbran (`mucosa`), kin dכn pwεl. Dis damej de mek yɔlɔ-wayt, tik, krɔst plek dɛn fɔm na di say dɛn we dɔn pwɛl. Dɔktɔ dɛn kin kɔl dɛn tin ya ‘pseudomembranes’.

Wetin na ‘pseudomembranes’?

di pseudomembranes na wetin de fכm we di sεl dεm na di layn na di big intestinal, lεk di layn na di big intestinal, day. Tink bɔt am dis we: we pɔsin wund, wi imyun sistɛm kin sɛn wayt blɔd sɛl dɛn to di sayt. semweso, na ya bak, di dεd sεl fragmεnt dεm de kam togεda wit wayt bכdi sεl dεm (especially nyutrofil dεm) fכ mek pseudomembranes. Dɛn wan ya wayd lɛk 2 sɛntimita, dɛn wayt lɛk yɔlɔ, ɛn dɛn kin rayz smɔl na di say we dɛn de.

Wetin na di sayn dɛm fɔ dis sik?

Pɔrsin wae gɛt pseudomembranous colitis kin gɛt sɔm kayn sik lɛk:

• Bɔku pen na yu bɛlɛ.
• Rɔnbɛlɛ. Dis kin apin bɔku tɛm insay di de, sɔm tɛm dɛn kin apin lɛk wata.
• Fiva.
• Vɔmit.
• Sɔmtɛm, yu kin si blɔd ɔ pus de kɔmɔt na yu stɔl, bɔt dis nɔ kin apin to ɔlman.

Wetin kin mek pɔsin gɛt Pseudomembranous Colitis?

di men εn mכst kכmכn kכz fכ dis na infεkshכn wit di baktri dεm `C. diff` (Klɔstridioides difisil). di tכxin dεm we dis bכdi de mek de pwεl di layn na di big intestin. Na lɛk 10% pan `C. diff` infεkshכn kin go bifo to wan mכr siriכs kכndyushכn we dεn kכl `pseudomembranous colitis.` Infakt, 90% pan dεn kes dεm ya na di `C. diff` baktri dɛm. Bɔt ɔda inflammatory bowel conditions kin mek dis kayn damej bak.

Aw di C. difficile baktri dεm de afekt dis?

di baktri we C. difficile de mek tכxin dεm we de pwεl di sεl dεm we de layn wi big intestin. Dis infεkshכn kin spre kwik εn bad bad wan pas aw yu kin tink.

Bɔrku tɛm, yu kin gɛt C. diff infɛkshɔn bikɔs yu gɛt ɔda sik.Afta yu dɔn yuz antibayɔtiks. Tink bɔt am, we yu tek antibayɔtik, di ɔda "gud" baktri dɛm na wi gut we de ɛp wi fɔ day. Bɔt, bɔku pan di antibayɔtik nɔ kin ebul fɔ kil dis `C. diff` baktri dɛm. So, we dɛn gud baktri dɛn de dɔn, di `C. diff` baktri dεm gεt di chans fכ gro εn spre we dεn nכ de chεk, we de mek dεn prכblεm ya we nכ de kכmpεtishכn.

Us antibayɔtiks kin wok fayn pas ɔl pan dis sik?

infakt, eni antibaytik we kil di gud baktri dεm na wi intestinal εn we nכ afekt di C. diff baktri dεm kin mek C. diff infεkshכn εn di pseudomembranous colitis we de kכmכt. Bɔt dɛn tink se sɔm antibayɔtik dɛn kin mek pɔsin gɛt mɔ prɔblɛm. Sɔm pan dɛn na:

• Klindamaysin we dɛn kɔl
• Sɛfalosporin klas fɔ drɔgs
• Penisilin grup fɔ drɔgs
• Fluoroquinolones we dɛn kɔl fluoroquinolones
• Aztreonam we dɛn kɔl Aztreonam
• Kabapɛnem dɛn

Impɔtant: Dis nɔ min se dɛn antibayɔtik ya bad. If dɔktɔ tɛl yu fɔ yuz dɛn, yu fɔ yuz dɛn as nid de. Bɔt if yu yuz antibayɔtik we yu nɔ nid, dat kin mek yu gɛt prɔblɛm dɛn lɛk dis.

Yu tink se ɔda rizin dɛn de?

Pseudomembranous colitis kin apin bak we inflameshn na di kכlon we kכz fכ כda kכz dεm, כda pas C. diff. Na sɔm ɛgzampul dɛn ya:

• Stafylokokɔs ɔriɔs infɛkshɔn
• E. coli infεkshכn `(E. coli infεkshכn)`
• Saytomegalovayrɔs infεkshɔn
• Maykroskɔpik kɔlaytis
• Di sik we Behçet gɛt
• Ischemic colitis (inflameshɔn we kin kam bikɔs di blɔd nɔ de go na di kɔlon) .
• Anti-kansa drɔgs `(Kɛmotɛrapi drɔgs)`
• Yuz kɔkɛyn
• Vasculitis (we de mek di blɔd vesel dɛn wam) .
• Hevi mɛtal pɔyzin

Insay dɛn kayn tin ya, di sik kin tranga ɔr kin kɔmplikt pas nɔmal kɔlayt. sכmtεm, di bכdi fכ fכlכ to di insay wכl na di kכlon de rεdכks (ischemia), di tisu dεm de day (nεkrכsis), εn pseudomembranes de divεlכp. כlso, sik dεm we bin de bifo lεk Inflammatory Bowel Disease (IBD) kin mek bak di kכlon izi fכ dis kכndyushכn.

Udat de pan big risk fɔ gɛt dis sik?

Yu kin gɛt pseudomembranous colitis if yu:

• If yu de na ɔspitul.
• If yu jɔs dɔn yuz antibayɔtiks.
• If dɛn jɔs dɔn du ɔpreshɔn pan yu.
• If pɔsin de na say usay dɛn de kia fɔ ol pipul dɛn.
• If yu dɔn pas 65 ia.
• If yu gɛt wan sik we de mek yu nɔ ebul fɔ fɛt di sik.
• If yu imyun sistɛm wik.
• If yu dɔn ɔlrɛdi gɛt C. diff infɛkshɔn.

Wetin na di poshubul kɔmplikeshɔn dɛm fɔ Pseudomembranous Colitis?

If dis sik kin tranga ɛn i nɔ kin izi fɔ kɔntrol, sɔm prɔblɛm dɛn we kin mek pɔsin denja kin apin. So i impɔtant fɔ no bɔt dis bak.

• dihaydreshכn εn εlektrolayt lכs: Insay siriכs pseudomembranous colitis, dayariya kin apin te to 10-15 tεm insay di de. Dis kin mek di wata nɔ de na di bɔdi ɛn i kin mek di ilɛktrɔlayt lɔs. Dis kin mek yu gɛt prɔblɛm dɛn we de mek yu gɛt prɔblɛm lɛk we yu blɔd nɔ de bɔku, yu blɔd prɛshɔn go dɔŋ, ɛn yu kidni nɔ de wok fayn.
• Fluid lik: Fluid kin lik frכm di damej wכl na di big intestכn insay di bכdi kכva, we kin mek di bכdi swel. Dɛn kɔl dis ascites. di protin dεm lεk albumin kin lכs bak frכm di big intestin. we di albumin dכn sכmtεm, wata de lik kכmכt na di bכdi vεsul dεm, we de mek di limb dεm swel (edema).
• Toxic megacolon: Na wan bad bad inflamɛns we dɛn nɔ kin kɔntrol na di kɔlon we kin mek di kɔlon swel pasmak ɛn stɔp fɔ wok. fכs, di mכsul dεm na di kכlon stכp fכ kכntrakt, we de blכk di pasεj fכ stכl. as di kכlon de kכntinyu fכ swel, in wכl dεm kin brok, we de mek di tin dεm we de insay de lik insay di bכdi. Dɛn kɔl dis peritonitis. Dis kin mek pɔsin in layf de pan denja.
• di gεstrointestinal pεrforeshכn: wan ol na di wכl na di big intestinal kin apin we nכ gεt tכxik megakolon. dis kin apin if כlsa de divεlכp na di big intestinal εn go tru di wכl, כ if signifyant tisu dεm de day (nεkrכsis) na di big intestin wכl. we di baktri dεm we de na di big intestin lik insay di bכdi (peritonitis), dεn kin spre insay di bכdi (septicemia).
• Sepsis: Sepsis na wan kכndyushכn we de kכz fכ di baktri dεm we de kכmכt na di bכdi (septicemia). Sepsis na wan bad bad sik we de mek pɔsin in layf de pan denja ɛn we kin skata ɔlsay na di bɔdi. Dis kin mek yu gɛt sɛptik shɔk, bɔku ɔgan dɛn nɔ de wok fayn, ɛn ivin day.

Dɛn kɔmplikeshɔn ya kin mek yu fred fɔ yɛri bɔt. Bɔt mɛmba se dɛn nɔ kin apin to ɔlman. If yu no di sik kwik kwik wan ɛn trit yu fayn, dat kin mek yu nɔ gɛt dɛn siriɔs sik ya.

Aw fɔ no bɔt dis sik?

Dɔktɔ go aks yu fɔs bɔt yu sik ɛn yu wɛl bɔdi istri. Dɔn, dɛn kin ɔda fɔ du difrɛn tɛst fɔ no wetin mek yu gɛt di sik. Fɔ ɛgzampul, dɛn kin ɔda fɔ mek dɛn du blɔd tɛst, fɔ tek imej lɛk fɔ skan, ɛn fɔ tɛst pɔsin we gɛt poop. Dɛn tɛst ya kin luk fɔ infekshɔn, inflamɛns, ɛn ɔda tin dɛn we kin mek pɔsin gɛt dis sik.

Yu stכl tεst go spεshal chεk fכ C. diff infεkshכn. If dɛn fɛn am, dɛn go bigin fɔ trit am wantɛm wantɛm. If yu nɔ gɛt ɛni prɔblɛm ɛn yu de ansa fayn to tritmɛnt, nɔr kin gɛt ɛni patikyula rizin fɔ luk insay yu big intestin fɔ pseudomembranes.

sכmtεm, imej tεst (lεk CT skan) kin sho sayn dεm fכ pseudomembranous colitis. if di kכlon wכl tik (we fiba "thumbprint sayn" כ "accordion sign"), di dכkta kin disayd fכ du כda tεst dεm.

Neks, fכ luk dip, yu nid fכ du wan tεst we de luk insay di big intestin. Dɛn kɔl am kɔlonɔskɔpi. insay dis, dεn de yuz tכb wit kεmεra fכ luk insay di big intestin. if yu si di tin we dεn kכl ‘pseudomembrane’, dεn kin tek sכm sכm tisu (bayopsi) frכm am εn sεn am na labכtכri fכ kכnfכm di sik.

Wetin na di tritmɛnt dɛn?

Di tritmɛnt de dipen pan wetin de mek dis sik kam.

• If na baktri infεkshכn lεk C. diff, yu go nid fכ gi spεshal antibaytik dεm we de wok fכ am.
• If na ɔda mɛrɛsin we yu de tek mek dis sik ɔr mek i wɔs, yu kin nid fɔ stɔp ɔ chenj da mɛrɛsin de.
• Sɔntɛnde, dɛn kin gi dɛn mɛrɛsin fɔ ridyus di inflamɛns na di big intestin.

Sɔm pipul dɛn jɔs nid sɔpɔt fɔ kia fɔ dɛn. fכ egzampl, intravenכs fכluid (IV fluid) fכ εp fכ rεtεn wata, כ IV nyutrishכn fכ εp di kכlon rεst. Ɔda pipul dɛn kin nid fɔ gɛt tritmɛnt fɔ prɔblɛm dɛn, sɔntɛm na say usay dɛn de kia fɔ pipul dɛn we sik bad bad wan. Sɔm pipul dɛm wae gɛt kɔlayt wae rili siriɔs ɔr kɔmplikeshɔn kin nid fɔ gɛt kɔlektɔmi (ɔpareshɔn fɔ pul di pat pan di kɔlon we dɔn pwɛl).

Wetin na di men mɛrɛsin dɛm we dɛn kin gi if na `C. difrɛns`?

If di kɔz fɔ pseudomembranous colitis na C. diff infɛkshɔn, sɔm mɛrɛsin dɛn de fɔ trit am. Yu dɔktɔ go pik di wan we bɛtɛ fɔ yu. Di mɛrɛsin dɛm we dɛn kin gi fɔ C. diff infɛkshɔn na:

• Metronidazol we dɛn kɔl
• Vankomaysin we dɛn kɔl
• Fidaksomisin we dɛn kɔl fidaxomicin

Yu kin ebul fɔ protɛkt Pseudomembranous Colitis?

Di impɔtant we fɔ mek dɛn nɔ gɛt dis sik na fɔ kɔntrol di we aw C. diff baktri de prɛd na di kɔmyuniti dɛn we gɛt ay risk (espɛshali ɔspitul ɛn nɔs os). Pipul dεm na dεn sεtin ya kin gεt infεkshכn εn dεn kin gεt siriכs simptom lεk pseudomembranous colitis.

So, di wan dɛn we de wok na di wɛlbɔdi biznɛs na dɛn kayn institiushɔn ya kin tek spɛshal step fɔ kɔntrol C. diff infɛkshɔn:

• Isolation: Dɛn kin put pipul dɛn we gɛt C. diff na wan sɛpret rum, ɔ na rum we dɛn kin sheb wit ɔda pipul dɛn nɔmɔ we gɛt di sik. Dɛn kin yuz glɔv dɛn we dɛn kin yuz wan tɛm nɔmɔ we dɛn de go insay di rum.
• Wash yu an: Fɔ was yu an ɔltɛm wit sop ɛn wam wata na di bɛst we fɔ protɛkt yusɛf frɔm C. diff. Dis baktri nɔ kin ebul fɔ yuz di tin dɛn we dɛn kin yuz fɔ was yu an. I impɔtant mɔ fɔ was yu an bifo yu ol it.
• Disinfɛkshɔn: Disinfɛkshɔn we dɛn kin yuz ɔltɛm nɔ kin kil C. diff. Bɔt, di tin dɛn we dɛn mek wit klorin kin. I impɔtant fɔ disinfɛkt ɔl di say dɛn we di pɔsin we gɛt di sik dɔn kam wit gud gud wan.

Yu tink se dɛn go ebul fɔ mɛn dis sik kpatakpata? Wetin na di nɔmba fɔ pipul dɛn we de day?

Yes, pseudomembranous colitis kin kכmplit kכl wit tritmεnt. Bɔrku tɛm, di sayn dɛm go dɔn kwik kwik wan. Bɔt sɔm pipul dɛn kin nid mɔ tritmɛnt ɛn fɔ lɔng tɛm pas ɔda wan dɛn. If yu gɛt C. diff infɛkshɔn we nɔ de dɔn, we at fɔ kɔntrol, yu kin nid fɔ du smɔl ɔpreshɔn fɔ trit am. Sɔntɛnde, i kin nid fɔ du ɔpreshɔn.

We i kam pan di pipul dɛn we de day, na 2% nɔmɔ pan di wan dɛn we gɛt pseudomembranous colitis de day. Bɔt pan pipul dɛm wae gɛt lɔng tɛm kia ɛn wae dɛn imyun sistɛm wik, dis rεt kin rich 15%. if di komplikashכn we wi bin dכn mεnshכn we dεn kכl tכxik mεgakolon apin, di mכtalman rεt kin go כp to 35%. Na dat mek i impɔtant fɔ gɛt tritmɛnt kwik kwik wan.

Ustɛm yu fɔ go to dɔktɔ?

If yu gɛt ɛni wan pan dɛn sik ya, go to dɔktɔ wantɛm wantɛm:

• Bɛlɛ pen bad bad wan ɔ blo.
• If yu gɛt dayarɛa pas fayv tɛm insay di de.
• If blɔd de na di stɔl.
• If yu nɔ bin dɔn gɛt bɔdi fɔ tri dez.
• If yu nɔ pis fɔ wan de, ɔ if yu urine gɛt dak kɔlɔ.
• If yu gɛt fiva we pas 39 digri sɛlshiɔs (102 digri F) fɔ tri dez.

Fɔ dɔn, tin dɛn we wi fɔ mɛmba

Baktri infεkshכn wae de mek yu gεt kolεt na kכmכn, εn bכku tεm dεn nכ kin siriכs. Nɔto ɔlman we gɛt C. diff go gɛt pseudomembranous colitis. Bɔt if yu du dat, i kin mek yu fred smɔl. Fɔ no se yu kɔlon de pwɛl frɔm insay kin mek yu fred, wit sɔm sayn dɛm lɛk pen ɛn blɔd.

If yu gɛt sɔm kayn sik lɛk dis, yu go nid spɛshal dɔktɔ. Bɔt mɛmba se if yu trit yu fayn fayn wan, yu kɔlon kin wɛl.di mכkus mεmbran dεm, lεk di layn na wi kכlon, kin hεl fayn fayn wan we dεn nכ dכn pwεl. If yu fil lɛk se yu kɔlayt sik nɔ de bɛtɛ, tɔk to dɔktɔ. I kin ɛp yu fɔ no wetin mek yu sik, du wetin nid fɔ stɔp am, ɛn gi yu kɔlon di rɛst we i nid. Di tin we impɔtant pas ɔl na fɔ nɔ panik ɛn go to dɔktɔ kwik kwik wan.

` Pseudomembranous Colitis, C. diff, dayarɛa, bɛlɛ at, kɔlayt, antibaytik