Fɔ bigin tritmɛnt fɔ kansa fɔ yu ɔr pɔrsin wae yu lɛk kin bi strɛs ɛn kɔnfyus tɛm. Yu kin gɛt kwɛstyɔn bɔt di mɛrɛsin dɛn we yu dɔktɔ de gi yu, dɛn nem, ɛn di bad tin dɛn we kin apin to yu. So tide wi go tɔk bɔt wan pan dɛn kayn spɛshal kansa mɛrɛsin ya, Selpercatinib . Yu kin sabi am bay di brand nem Retevmo. Lɛ wi tɔk bɔt dis drɔg, wetin i de du, ɛn wetin fɔ no bɔt insay wan simpul we we izi fɔ ɔndastand.
Wetin kin rili apin wit dis mɛrɛsin?
Fɔ tɔk am simpul wan, Selpercatinib nɔ tan lɛk tradishɔnal kemotɛrapi. I de wok lɛk "targeted therapy." sכm protin dεm na wi bכdi de sεnd signal to di kεnsar sεl dεm fכ "grכ mכr, spre fast." Tink bɔt am lɛk swich we de mek di kansa sɛl dɛn gro. wetin Selpercatinib de du na fכ deaktiv di protin we de sεnd di rכng signal . I tan lɛk se yu dɔn ɔf da switch de. Dɔn dɛn kin kɔntrol di we aw di kansa sɛl dɛn de gro ɛn skata ɔlsay na di bɔdi.
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu bigin fɔ tek mɛrɛsin
Bifo yu bigin dis tritmɛnt, yu dɔktɔ fɔ gɛt kɔmplit pikchɔ bɔt yu wɛlbɔdi. Mek shɔ se yu tɛl dɛn bɔt ɛni wan pan dɛn tin ya, mɔ if yu gɛt ɛni wan pan dɛn:
| Yu gɛt dis sik? | Wetin mek i impɔtant fɔ notis pɔsin? |
|---|---|
| Di prɔblɛm dɛn we kin apin we pɔsin de blɔd | Dis mɛrɛsin kin mek yu gɛt mɔ blɔd. |
| Bikɔs dɛn jɔs dɔn du am ɔ dɛn dɔn arenj fɔ mek dɛn du am ɔpreshɔn tumara bambay | Di mɛrɛsin kin mek di wund nɔ wɛl. |
| Di ay blɔd prɛshɔn | Di mɛrɛsin kin mek di blɔd prɛshɔn go ɔp mɔ. |
| Di at we nɔ de bit ɔltɛm | Di chenj dɛn we de apin na di at rit kin apin. |
| Liva ɔ lɔng sik dɛn | Di wok we dɛn ɔgan ya de du kin afɛkt. |
| Alɛji to ɔda mɛrɛsin, it, ɔ day | I impɔtant fɔ no if yu gɛt alɛji fɔ di mɛrɛsin ɔ ɛni wan pan di tin dɛn we de insay am. |
| Fɔ gɛt bɛlɛ ɔ fɔ tray fɔ gɛt bɛlɛ | Dis mɛrɛsin kin ambɔg di pikin we de na in bɛlɛ bad bad wan. |
| Fɔ gi pikin in mama in bɛlɛ | di mεdisin kin pas to di pikin tru in mama in milk. |
Aw a fɔ yuz dis mɛrɛsin?
Dis na kapsul we yu de tek wit yu mɔt. I rili impɔtant fɔ tek am di sem tɛm ɛvride , jɔs lɛk aw yu dɔktɔ dɔn tɛl yu.
- Swɛla di kapsul ɔl wit wata . Nɔ brok, krɔs, ɔ chew di kapsul.
- Yu kin tek dis wit it ɔ yu nɔ it am. Bɔt if yu fil se yu bɛlɛ at smɔl, i go fayn fɔ tek am wit yu it.
- Kɔntinyu fɔ trit yu te yu dɔktɔ tɛl yu fɔ stɔp.
- I rili impɔtant: Nɔ drink grep jus ɔltogɛda we yu de tek dis mɛrɛsin.
Wetin a go du if a mis wan doz fɔ tek mɛrɛsin?
If yu mis wan doz, tek am jɔs afta yu mɛmba. Bɔt if i pas 18 awa pas yu nɛks doz (we min se i nɔ rich 6 awa te yu nɛks doz), skip di doz we yu mis ɛn tek yu nɛks doz di tɛm we yu de tek am ɔltɛm. Nɔ ɛva tek tu doz wan tɛm fɔ mek di doz we yu mis.
Wetin a go du if a tek bɔku mɛrɛsin?
If yu tink se yu dɔn tek mɔ mɛrɛsin pas aw yu tink, nɔ panik. Go na di ɔspitul we de nia yu Imejɛnsi Dipatmɛnt (ETU) wantɛm wantɛm. Ɔ, kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital fɔ advays.
Ɔda tin dɛm wae kin miks wit dis mɛrɛsin
Sɔm mɛrɛsin kin intarakt wit Selpercatinib, chenj in effektiv ɔr inkrisayz sayd ɛfɛkt.
Wonin: If yu de tek ɛni wan pan dɛn mɛrɛsin ya, nɔ tek Selpercatinib. Tɔk to yu dɔktɔ bɔt dis.
* Sisaprid we dɛn kɔl Cisapride
* Dronedarone we dɛn kɔl Dronedarone
* Kɛtokonazɔl we dɛn kɔl
* Lɛvokɛtokonazɔl
* Pimozayd we dɛn kɔl Pimozid
* Tioridazin we dɛn kɔl Tioridazin
Apat frɔm dat, ɔda mɛrɛsin dɛn, ɛbul tin dɛn, ɛn it dɛn kin miks wit dis mɛrɛsin. So, i impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek (inklud vaytamɛn dɛn, ɛbul mɛrɛsin dɛn, ɛn sɔpɔtmɛnt dɛn).
- Sɔm mɛrɛsin dɛn we gɛt ay blɔd prɛshɔn (diltiazem ɔ verapamil) .
- Sɔm antivayrɔs drɔgs fɔ HIV ɔ Epatitis
- Mεdisin dεm fכ fεnshכn infεkshכn (itraconazole, posaconazole) .
- Grepfruit jus we dɛn kin mek
- Ɔda mɛrɛsin dɛn we de chenj di at rit
- Repaglinide fɔ gɛt dayabitis
- Rifampin fɔ TB
- Herbal prodak dɛm lɛk Sɛnt Jɔn Wɔt
- Mɛrɛsin dɛn we de ridyus di asid na di bɛlɛ (lɛk simɛtidin, famotidin, ranitidin, lansoprazole, ɔmɛprazɔl) .
Tin dɛn we yu fɔ tek tɛm wit mɔ we yu de tek di mɛrɛsin
- Fɔ fil fayn: Na nɔmal tin fɔ fil fayn smɔl ɔ nɔr wɛl we yu de tek dis mɛrɛsin. Dis na bikɔs dis mɛrɛsin kin afɛkt ɔl tu di kansa sɛl dɛn ɛn di wɛlbɔdi sɛl dɛn te to sɔm mak. Bɔt nɔ stɔp di tritmɛnt te yu dɔktɔ tɛl yu fɔ du dat. Tɛl yu dɔktɔ bɔt ɛni sayd ɛfɛkt we yu gɛt.
- Ɔpreshɔn: If yu go gɛt ɔpreshɔn (ilɛksɛf na smɔl tin lɛk fɔ pul yu tut), tɛl yu dɔktɔ. Dis mɛrɛsin kin mek wund nɔ wɛl. So, yu go nid fɔ stɔp fɔ tek di mɛrɛsin at le 7 dez bifo di ɔpreshɔn ɛn bigin bak 2 wik afta di ɔpreshɔn, we di wund dɔn wɛl ɔl.
- Bεlε εn bεlε: Fכ uman dεm: Nɔ bεlε we yu de tek dis mεrεsin εn fכ wan wik afta yu stכp di mεrεsin. Dis na di rizin we mek i impɔtant fɔ yuz wan we we pɔsin kin abop pan fɔ kɔntrol pikin. Yu fɔ tek bɛlɛ tɛst bifo yu bigin di mɛrɛsin fɔ mek shɔ se yu nɔ gɛt bɛlɛ. Dɔn bak, nɔ fɔ gi pikin in bɛlɛ dis tɛm ɛn fɔ wan wik afta yu dɔn stɔp di mɛrɛsin. Fɔ man dɛn: Yuz kɔndɔm ɔltɛm if yu du mami ɛn dadi biznɛs wit uman we kin gɛt bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ wan wik afta yu dɔn stɔp di mɛrɛsin. If yu patna gɛt bɛlɛ, i kin ambɔg di pikin we de na di bɛlɛ.
- Fɔ bɔn pikin: Dis mɛrɛsin kin afɛkt di we aw yu ebul fɔ bɔn pikin. Tɔk to yu dɔktɔ if yu gɛt ɛnitin fɔ wɔri bɔt dis.
- Blɔd prɛshɔn:Chek yu blɔd prɛshɔn ɔltɛm lɛk aw yu dɔktɔ tɛl yu. No wetin i fɔ bi ɛn ustɛm yu fɔ kɔl yu dɔktɔ.
Us sayd ɛfɛkt dɛn we a go gɛt?
Lɛk ɛni mɛrɛsin, Selpercatinib kin mek yu gɛt sayd ɛfɛkt. Sɔm kin siriɔs, ɛn ɔda wan dɛn kin kɔmɔn.
| Sayd ɛfɛkt we pɔsin kin gɛt | Tɔk bɔt |
|---|---|
| Sayd ɛfɛkt dɛn we yu fɔ ripɔt to yu dɔktɔ wantɛm wantɛm | |
| Alɛji we pɔsin kin gɛt | Skin rash, it, swel na di fes, lip, tong ɔ trot. |
| Blɔd we nɔ de kɔmɔt fayn | Blak ɔ blɔd stɔl, blɔd we de vɔmit we tan lɛk kɔfi grɔn, dak brawn/rɛd urine, rɛd/pɔpul spat na di skin. |
| I nɔ izi fɔ blo | Dray kɔf, i nɔ izi fɔ blo. |
| Di chenj dɛn we de apin na di at rit | At de bit, diziz, chɛst de pen. |
| Liva injuri | Pen na di ɔp rayt say na di bɛlɛ, yu nɔ de want fɔ it, yu skin ɔ yu yay de yɔlɔ, yu stɔl we gɛt layt kɔlɔ, yu urine we gɛt dak yɔlɔ/brawn. |
| Di sik we dɛn kɔl haypotayroyd | Taya we nɔ kɔmɔn, nɔ ebul fɔ bia wit kol, kɔnstipɛshɔn, ia we de lɔs, dray skin, wet we yu de gɛt. |
| Tumɔr Lisis Sindrom (TLS) . | Vɔmit, dayarɛa, yu nɔ de pis smɔl, yu mɔsul dɛn de twitch, yu jɔyn dɛn de pen, yu kɔnfyus. |
| Tɛl yu dɔktɔ if i kɔntinyu fɔ de ɔ i de mɔna yu. | |
| Kɔnstipɛshɔn, dayarɛa, mɔt we dray, nɔs, skin rɔsh, anklɛ, fut, ɛn an dɛn we de swel. | |
Dis list nɔ de inklud ɔl di sayd ɛfɛkt dɛn we pɔsin kin gɛt. If yu gɛt ɛnitin we nɔ kɔmɔn, tɔk to yu dɔktɔ bɔt am.
Mɛsej we dɛn kin kɛr go na os
- Selpercatinib na dכg we de tכk εn deaktiv wan spεsifi k protin we de involv fכ kεnsar sεl gro.
- Tek di mɛrɛsin di sem tɛm ɛvride lɛk aw yu dɔktɔ tɛl yu fɔ tek am. Nɔ ɛva tek am wit grep jus.
- Tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn (inklud vaytamɛn ɛn ɛbul prɔdak dɛm) we yu de tek.
- Dis mɛrɛsin nɔ fayn if yu gɛt bɛlɛ, yu de tray fɔ gɛt bɛlɛ, ɔ yu de gi pikin in bɛlɛ. I impɔtant fɔ mek uman ɛn man yuz di rayt bɔn kɔntrol we dɛn de du di tritmɛnt ɛn fɔ wan wik afta dat.
- If yu gɛt ɛni siriɔs sayd ɛfɛkt lɛk fɔ gɛt prɔblɛm fɔ blo, fɔ blɔd pasmak, ɔ fɔ gɛt siriɔs alɛji, go to dɔktɔ wantɛm wantɛm.
- Nɔr frayd fɔ tɔk to yu dɔktɔ bɔt ɛni kwɛstyɔn ɔr tin wae de mɔna yu. Mɛmba se nɔto yu wangren de.
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