Sɔntɛm yu ɔ sɔmbɔdi na yu famili jɔs dɔn gɛt ɔgan transplant, lɛk kidni. Ɔ sɔntɛm dɛn de trit yu fɔ wan sik we nɔ kin apin na yu lɔng. Insay dɛn kayn tin ya, yu dɔktɔ kin gi yu wan mɛrɛsin we dɛn kɔl Sirolimus fɔ ɛp fɔ kɔntrol di wok we yu imyun sistɛm de du. So bikɔs dis na smɔl kɔmplikɛt mɛrɛsin, lɛ wi tɔk bɔt am simpul wan ɛn klia wan, nɔto so?
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Wetin kin rili apin wit dis mɛrɛsin?
Fɔ tɔk am simpul wan, Sirolimus na drɔg we de ridyus ɔ stɔp di wok we yu bɔdi in imyun sistɛm de du. Tink bɔt am dis we: we pɔsin gɛt nyu ɔgan transplant, wi bɔdi kin si am as "fɔrin." So di bɔdi in natura difens sistɛm de tray fɔ atak di nyu ɔgan, ɔ nɔ gri fɔ tek am. Sirolimus de stɔp da rijɛkt de. i de εp bak fכ kכntrכl di abnכmal growth fכ di sεl dεm na di lכng, wan sik we nכ kin apin na di lכng we dεn kכl lymphangioleiomyomatosis.
Tin dɛn we yu fɔ tɛl yu dɔktɔ bifo yu tek mɛrɛsin
Bifo yu bigin dis mɛrɛsin, i rili impɔtant fɔ tɛl yu dɔktɔ bɔt yu kɔmplit wɛlbɔdi stetmɛnt. Mek shɔ se yu tɛl dɛn if yu gɛt ɛni wan pan dɛn tin ya:
- Shuga
- At sik
- di kכlestכl כ triglisεrayd dεm we de na di bכdi de go כp
- Eni kondishon wae de infεkshכn naw
- Sik dɛn we kin apin na di liva
- If yu gɛt alɛji fɔ sirolimus ɔ ɛni ɔda mɛrɛsin, it, ɔ day.
- If yu gɛt bɛlɛ, yu de tray fɔ gɛt bɛlɛ, ɔ yu de gi pikin in bɛlɛ
Fɔ gi dis infɔmeshɔn to yu dɔktɔ impɔtant fɔ gi yu di tritmɛnt we fit ɛn sef.
Aw ɛksaktɔli a kin yuz dis mɛrɛsin?
Dis na mɛrɛsin we kin kam insay wata, so yu nid fɔ fala dɛn step ya jɔs we yu de yuz am.
1. Yuz di kɔrɛkt sirinj: Yuz di amber sirinj nɔmɔ we de kam wit di mɛrɛsin. Nɔ mɛzhɔ wit kichin spun, bikɔs dɛn nɔ go gi yu kɔrɛkt doz. Yuz nyu sirinj fɔ ɛni doz ɛn trowe am afta yu dɔn yuz am.
2. Miks di mɛrɛsin: Put di mɛrɛsin we yu dɔn mɛzhɔ insay glas ɔ plastic kɔp. Ad 60 mililita (lɛk 2 ɔns) wata ɔ ɔrɛnj jus pan am. Nɔ ɛva miks wit grep jus ɔ ɛni ɔda wata.
3. Drink: Stir gud gud wan ɛn drink wantɛm wantɛm.Drink am. Dɔn, ad ɔda 120 mililita (lɛk 4 ɔns) wata ɔ ɔrɛnj jus to di sem kɔp, stir am bak, ɛn drink dat bak. Dis go ɛp fɔ pul ɛni mɛrɛsin we lɛf na di kɔp.
4. Tek am di rayt tɛm: Gɛt di abit fɔ tek yu mɛrɛsin di sem tɛm ɛvride. Yu kin tek am wit it ɔ yu nɔ it am, bɔt stik to wan we. Fɔ ɛgzampul, if yu tek am afta yu dɔn it ɛvride, du am da we de.
5. If yu tek am wit Cyclosporine: If yu de tek Cyclosporine bak, yu fɔ tek Sirolimus 4 awa afta yu tek am.
Wetin fɔ du if yu mis wan doz fɔ mɛrɛsin?
If yu mis wan doz, tek am jɔs afta yu mɛmba. Bɔt if i dɔn lɛf smɔl fɔ lɛ yu tek yu nɛks doz, skip di doz we yu mis ɛn tek yu nɛks doz di tɛm we yu dɔn sɛtul. Nɔ ɛva tek dabl doz.
Mɛrɛsin wae nɔr fɔ yuse wit Sirolimus ɛn wae yu fɔ tek tɛm wit
Sirolimus na wan mɛrɛsin wae kin intarakt wit ɔda mɛrɛsin dɛm, so i rili impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl ɔda mɛrɛsin dɛm wae yu de tek.
| Di kayn mɛrɛsin dɛn ɛn di tin dɛn we dɛn kin du | |
|---|---|
| ❌ Tin dɛm we yu nɔ fɔ ɛva tek wit Sirolimus | |
| Antibayɔtiks | Lɛk Klaritromaysin, Ɛritromaysin, Tɛlitromaysin |
| Antifungals dɛn we dɛn kin yuz | Lɛk Itrakonazɔl, Kɛtokonazɔl, Vɔrikonazɔl |
| Ɔda | Grepfruit jus, Mifepriston, Rifampin, Rifabutin |
| ⚠️ Mɛrɛsin we yu fɔ yuz wit kɔt, afta yu dɔn tɛl di dɔktɔ | |
| Cyclosporine, Diltiazem, Verapamil (fɔ blɔd prɛshɔn), Carbamazepine, Phenytoin (fɔ fit), Sɛnt Jɔn wɔt (wan ɛbul mɛrɛsin), difrɛn vaysin dɛn, ɛn bɔku ɔda mɛrɛsin dɛn. | |
Impɔtant: Dis list nɔ kɔmplit. Tɛl yu dɔktɔ bɔt ɔl di tin dɛn we yu de tek, lɛk vaytamɛn, ɛbul mɛrɛsin, ɛn mɛrɛsin dɛn we yu nɔ de bay.
Tin dɛn we yu fɔ tek tɛm wit mɔ we yu de tek mɛrɛsin
- Fɔ chɛk yu dɔktɔ ɔltɛm: Kɔntinyu fɔ go na di klinik dɛn lɛk aw yu dɔktɔ tɛl yu fɔ du. Yu kin nid fɔ du blɔd tɛst ɔltɛm fɔ no aw yu sik.
- Protekshɔn frɔm infɛkshɔn: Dis mɛrɛsin de mek yu imyuniti go dɔŋ, so i kin izi fɔ gɛt infɛkshɔn lɛk kol ɛn flu. So, nɔ de nia ples dɛn we pipul dɛn kin ful-ɔp ɛn pipul dɛn we sik. If yu gɛt ɛni simptom fɔ infekshɔn (fiva, trot we de at), nɔ fɔ tek mɛrɛsin fɔ yusɛf ɛn kɔl yu dɔktɔ wantɛm wantɛm.
- Kɔlɔstrel ɛn shuga lɛvɛl: Dis mɛrɛsin kin mek yu blɔd kɔlɔstrel ɛn shuga lɛvɛl go ɔp. Yu dɔktɔ go wach dis ɛn gi yu sɛpret tritmɛnt if nid de.
- Fɔ protɛkt yusɛf frɔm di san: Yu skin go rili sɛnsitiv to san layt (fɔtosɛnsitiv) we yu de tek dis mɛrɛsin. So, if yu de go na do na di san, wɛr lɔng klos ɛn yuz gud tin fɔ protɛkt yusɛf frɔm di san.
- Risk fɔ gɛt kansa: Bikɔs ɔf di imyun sɔpreshɔn fɔ lɔng tɛm, i kin mek di risk fɔ sɔm kayn kansa (espɛshali kansa na di skin) go ɔp smɔl. Nɔ wɔri bɔt dis, bɔt tɔk to yu dɔktɔ bɔt am.
- Fɔ mek yu nɔ gɛt bɛlɛ: If yu na uman we dɔn rich di ej fɔ bɔn pikin, yu fɔ yuz wan we we rili wok fɔ mek yu nɔ bɔn pikin we yu de tek dis mɛrɛsin ɛn fɔ 12 wik afta yu dɔn stɔp di mɛrɛsin .
Sɔm sayd ɛfɛkt dɛn we pɔsin kin gɛt
Lɛk ɛni mɛrɛsin, Sirolimus kin mek yu gɛt sayd ɛfɛkt. Sɔm pan dɛn tin ya siriɔs, ɛn ɔda wan dɛn kin kɔmɔn.
| Sayd ɛfɛkt dɛn we dɛn fɔ ripɔt to di dɔktɔ wantɛm wantɛm | |
|---|---|
| Di sayn dɛn we de sho se pɔsin gɛt alɛji | Skin de rɔsh, it, swel na yu fes, lip, ɔ tong |
| I nɔ izi fɔ blo | I nɔ kin izi fɔ yu fɔ blo |
| Sayn dɛn we de sho se pɔsin gɛt di sik | Fiva, kol, trot we de at |
| Ɔda siriɔs sayn dɛn | urine dak, at bit fast ɔr nɔr de bit ɔltɛm, yu de fɔdɔm, yu blɔd prɛshɔn, yu de rɛd, fayn fayn say dɛn na yu skin, yu de swel we nɔ kɔmɔn, i nɔ izi fɔ pis, yu de blɔd ɔ brus we nɔ kɔmɔn, yu taya pasmak. |
| Di sayn dɛm we de sho se yu gɛt bɔku shuga | Tɔsti ɔ angri pasmak, pis ɔltɛm, taya pasmak, yu nɔ de si fayn. |
| Tin dɛn fɔ ripɔt if dɛn kɔntinyu ɔ de mɔna yu | |
| Bɔdi de at, akni, blo, nɔs, vɔmit, bɛlɛ pen, an dɛn we de shek shek, nɔ ebul fɔ slip. | |
Wetin a go du if a tek bɔku mɛrɛsin?
If yu tink se yu dɔn tek bɔku mɛrɛsin, kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta wantɛm wantɛm na di Kolombo Nashɔnal Ospital , ɔ go na di Imejɛnsi Tritmɛnt Yunit (ETU) na di ɔspitul we de nia yu.
Aw fɔ kip di mɛrɛsin kɔrɛkt wan?
- Stɔr di mɛrɛsin bɔtul na frij (bitwin 2 ɛn 8 digri sɛlshiɔs). Nɔ kip am na friza. Protɛkt frɔm layt.
- Trowe ɛni mɛrɛsin we lɛf insay 30 dez afta yu opin di bɔtul.
- If dɛn nid bɔtul we dɛn opin, dɛn kin kip am na rum tɛmpracha (dɔwn 25 sɛlshiɔs) fɔ te 15 dez.
- Yuz wan doz we dɛn drɔ insay di sirinj insay 24 awa. Yu kin kip am na frij ɔ na rum tɛmpracha. Trowe am if yu nɔ yuz am insay 24 awa.
- Kip am usay pikin dɛn nɔ go ebul fɔ rich.
Mɛsej we dɛn kin kɛr go na os
- Sirolimus na wan mɛrɛsin we rili impɔtant. Tek am jɔs lɛk aw yu dɔktɔ tɛl yu, insay di rayt doz, di rayt tɛm.
- Dis mɛrɛsin na fɔ yu nɔmɔ. Nɔ sheb am wit ɛni ɔda pɔsin fɔ ɛni rizin.
- Tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn we yu de tek ɛn ɔl di mɛrɛsin dɛn we yu gɛt.
- Protɛkt yusɛf frɔm infɛkshɔn. Tek tɛm wit di san.
- If yu gɛt ɛni siriɔs sayd ɛfɛkt, go to dɔktɔ wantɛm wantɛm.
- Nɔ mis yu dɔktɔ in apɔntinmɛnt dɛn. I rili impɔtant fɔ yu wɛlbɔdi.
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