Dɔktɔ dɔn gi yu ɔr pɔrsin wae yu sabi mɛrɛsin fɔ sik lɛk pwɛl hat? If na so, yu go mɔs dɔn yɛri di nem SNRI. Na nɔmal tin fɔ mek bɔku kwɛstyɔn dɛn kam na yu maynd we yu yɛri dis nem. "Wetin na SNRI? Aw dɛn kin rili wok? Ɛni sayd ɛfɛkt de?" Yu go mɔs gɛt kwɛstyɔn dɛn lɛk dis bak. No wori, okay, den, mek wi tok abaut ol dis fo rili simpul and frenli we tide.
Lɛ wi si fɔs, wetin na dɛn SNRI ya?
Fɔ tɔk am simpul wan, SNRI (Serotonin ɛn Norepinephrine Reuptake Inhibitors) na wan klas ɔf mɛrɛsin wae dɛn kin yuse fɔ kɔntrol di simptom dɛm fɔ mɛntɛl hεlth kɔndishɔn lɛk pwɛl hat. Bɔt, dɔktɔ dɛn kin gi dis mɛrɛsin fɔ bɔku ɔda sik dɛn, nɔto fɔ jɔs pwɛl at.
Insay Sri Lanka, dɔktɔ dɛn kin gi bɔku mɛrɛsin dɛn we de insay dis kategori. Fɔ ɛgzampul, mɛrɛsin dɛn lɛk Venlafaxine, Duloxetine, ɛn Desvenlafaxine de insay dis kategori. Bɔt , na yu dɔktɔ nɔmɔ go disayd us mɛrɛsin we fayn fɔ yu ɛn wetin na di mɛrɛsin.
Aw dis mɛrɛsin de wok insay di bɔdi?
Fɔ ɔndastand dis, wi fɔ no smɔl bɔt wi bren fɔs. Wi bren gɛt spɛshal kemikal mɛsenja dɛn we dɛn kɔl nyurotransmitta , lɛk postman dɛn we kin kɛr mɛsej bitwin difrɛn pat dɛn na wi bɔdi.
Pan dɛn tin ya , Serotonin ɛn Norepinephrine na tu pan di men mɛsenja dɛn we de kɔntrol bɔku impɔtant tin dɛn, lɛk aw wi de fil, aw wi de slip, aw wi de mɛmba tin, ɛn aw wi de pe atɛnshɔn.
Insay tin dɛm lɛk pwɛl hat, di wok we dɛn mɛsenja ya kin du kin go dɔŋ. dat min se dεn de abzכp bak kwik kwik wan insay di nεv sεl dεm afta dεn dכn gi di mεsej (dεn kכl dis riuptek). Dɔn di tin dɛn we dɛn kin du na di bren kin go dɔŋ.
SNRI dεm de wok bay we dεn de inhibit di riuptek fכ כl tu di sεrotonin εn norepinephrine. Dis min se dɛn tu mɛsenja ya kin de wok na di bren fɔ lɔng tɛm. Dis kin mek wi fil fayn ɛn di sayn dɛm fɔ pwɛl hat kin bigin fɔ stɔp smɔl smɔl.
So wetin na di difrɛns bitwin SSRI ɛn SNRI?
Sɔntɛm yu dɔn yɛri bɔt SSRI. SSRI dεm (Selective Serotonin Reuptake Inhibitors) dεn nכ de tכk bכt di nyurotransmitta sεrotonin, we SNRI dεm de afekt כl tu di sεrotonin εn norepinephrine.
Dis nɔ min se SNRI dɛn "bɛtɛ" pas SSRI dɛn. Sɔm pipul dɛn kin si se SSRI dɛn kin wok fayn, ɔda pipul dɛn kin si se SNRI dɛn kin wok fayn. Yu dɔktɔ go no uswan go fayn fɔ yu bay aw yu sik, di sayn dɛm, ɛn aw yu bɔdi de ansa dɛn.
Us sik dɛn dɛn kin yuz SNRI mɛrɛsin fɔ?
Dɛn kin yuz dis kayn mɛrɛsin fɔ mɛn difrɛn kayn mɛrɛsin. Lɛ wi tek wan luk pan wetin dɛn bi.
| Mɛdikal kɔndishɔn | Wan simpul ɛksplen |
|---|---|
| Major Dipreshɔn Disɔda | Sɔri-at fɔ lɔng tɛm ɛn nɔr kin gɛt intres wae kin afɛkt di tin dɛm wae yu kin du ɛvride. |
| Jɛnɛralized Anxiety Disɔda (GAD) we de mek pɔsin wɔri (GAD) . | Fɔ fil fɔ wɔri bɔt ɛvride tin we yu nɔ ebul fɔ kɔntrol fɔ no patikyula rizin. |
| Fibromyalgia we pɔsin kin gɛt | Pen we nɔ de dɔn ɔlsay na di bɔdi, taya, ɛn prɔblɛm wit slip. |
| Dayabitik Nyuropati | Pen, lɛk inflamɛns ɛn numbness, we kin kam bikɔs ɔf di nerve damej bikɔs ɔf dayabitis. |
| Pen we de mek pɔsin gɛt mɔskul ɛn skel we nɔ de dɔn | Pen we kin de fɔ lɔng tɛm, lɛk bak pen. |
| Sɔshial Wɔri Disɔda | Fɔ fred ɛn wɔri pasmak na sɔshal sityueshɔn. |
Apat frɔm dat, i kin dipen pan di ɛkspiriɛns we di dɔktɔ gɛt ɛn di we aw di dɔktɔ de tink, dɛn kin tɛl am bak fɔ tek dis mɛrɛsin fɔ swet na nɛt we gɛt fɔ du wit menopause, fɔ mek pɔsin nɔ gɛt maygren, ɛn ɔda tin dɛn we kin mek pɔsin wɔri.
Wetin na di kɔmɔn sayd ɛfɛkt dɛm we dɛn mɛrɛsin ya kin gɛt?
Lɛk ɛni mɛrɛsin, SNRI kin mek sɔm pipul dɛn gɛt smɔl smɔl sayd ɛfɛkt. Bɔt bɔku tɛm, dɛn tin ya kin apin fɔ shɔt tɛm . Bɔrku pan dɛn tin ya go stɔp insay di fɔs wik dɛm as yu bɔdi de ajɔst to di mɛrɛsin.
- Nɔs ɛn vɔmit
- Dray mɔt
- Banbɛlɛ
- Taya ɛn slip
- Diziz we pɔsin kin gɛt
- We pɔsin de swet pasmak
- Prɔblɛm wit di we aw pɔsin de du mami ɛn dadi biznɛs (e.g., we pɔsin nɔ want fɔ du mami ɛn dadi biznɛs) .
Di tin we impɔtant pas ɔl na dat if dɛn sayd ɛfɛkt ya de mɔna yu, nɔ ignore dɛn ɛn tɔk to yu dɔktɔ. I kin ebul fɔ ajɔst di mɛrɛsin we yu de tek ɔ gi yu ɔda mɛrɛsin.
Denja tin dɛn we nid fɔ pe atɛnshɔn mɔ pan
Pan ɔl we SNRI na mɛrɛsin we rili wok, sɔm tin dɛn de we nɔ kin apin so ɔltɛm bɔt we kin denja we wi fɔ no bɔt.
1. Di risk fɔ tink bɔt fɔ kil insɛf kin bɔku
Stɔdi dɔn sho se pipul dɛn kin tink mɔ bɔt fɔ kil dɛnsɛf, mɔ pan yɔŋ pipul dɛn we nɔ rich 25 ia yet, we dɛn fɔs bigin dis mɛrɛsin ɔ we dɛn chenj di doz. If yu ɔ yu pikin gɛt dɛn kayn tin ya we yu de tek dis mɛrɛsin, nɔ shem fɔ kɔntak yu dɔktɔ wantɛm wantɛm.
2. Sεrotonin Sindrכm
Dis na tin we nɔ kin apin so ɔltɛm, bɔt i kin mek pɔsin in layf de pan denja. i kin apin we di sεrotonin lεvεl dεm na di bכdi tu hכy. Dis risk kin hεvi spεshal we dεn tek SNRI wit כda mεdikeshכn dεm we de inkrεs di sεrotonin lεvεl (lεk MAOI). So, i rili impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek, ivin di vaytamɛn dɛn.
| Di simptom dɛm fɔ Serotonin Syndrome | |
|---|---|
| Jɛnɛral kwaliti dɛn | Nɔ rɛst, nɔs, dayarɛa, dilayt pupil, mɔsul dɛn de shek shek, swet, ɛn kol. |
| Di tin dɛn we de mek pɔsin denja | Kɔnfyushɔn, tachycardia, ay blɔd prɛshɔn, ay fiva, siz, nɔ no natin. |
| If yu gɛt ɛni wan pan dɛn denja sayn ya, go na di ɔspitul we de nia yu Imejɛnsi Dipatmɛnt (ETU) wantɛm wantɛm! | |
3. Fɔ stɔp di mɛrɛsin wantɛm wantɛm
If yu stɔp fɔ tek SNRI fɔ pas 6 wik, yu kin gɛt sɔm sayn dɛn we nɔ fayn. Dɛn kɔl dis Antidipreshan Diskɔntinyueshɔn Sindrom. Dis nɔto "drug adikshɔn." Dis na jɔs di bɔdi we de tray fɔ ajɔst to di mɛrɛsin we dɛn stɔp am wantɛm wantɛm. Di sayn dɛm kin bi wae yu bɔdi kin pen lɛk fiva, yu ed kin at, yu kin gɛt nɔys, yu ed kin tɔn, ɛn yu kin gɛt bɔz.
So , nɔ ɛva, fɔ ɛni rizin, stɔp fɔ tek dis mɛrɛsin wantɛm wantɛm we yu nɔ go to yu dɔktɔ. If yu nid fɔ stɔp fɔ tek di mɛrɛsin, du am lɛk aw yu dɔktɔ tɛl yu, ɛn smɔl smɔl yu fɔ ridyus di mɛrɛsin.
Aw lɔng i kin tek fɔ si di rizɔlt fɔ di mɛrɛsin?
Dis na kwɛstyɔn we bɔku pipul dɛn kin aks. I kin tek lɛk 6 to 8 wiks fɔ mek dɛn fil di ful ifɛkt dɛn we SNRI mɛrɛsin dɛn gɛt. Yu go bigin fil sɔm impɔtant tin afta di fɔs tu to tri wik. So, i impɔtant fɔ peshɛnt ɛn yuz di mɛrɛsin kɔrɛkt wan. If yu nɔ fil ɛni difrɛns afta dis tɛm, tɔk to yu dɔktɔ bɔt am.
Mɛsej we dɛn kin kɛr go na os
- SNRI na wan klas wae de woke fayn fayn wan wae de trit tin dɛm lɛk pwɛl hat, wɔri, ɛn pen wae nɔr de dɔn.
- Dis mɛrɛsin de wok bay we i de balans di lɛvɛl dɛn we di kemikal mɛsenja dɛn we dɛn kɔl sɛrotonin ɛn norepinephrine de na di bren.
- Di fɔs sayd ɛfɛkt dɛn kin bi fɔ shɔt tɛm nɔmɔ, bɔt if dɛn de mɔna yu, mek shɔ se yu tɛl yu dɔktɔ.
- Nɔ ɛva stɔp fɔ tek dis mɛrɛsin wantɛm wantɛm if yu dɔktɔ nɔ advays yu.
- Yu fɔ no di denja sayn dɛm wae de sho se yu gɛt serotonin syndrome (hay fiva, kɔnfyushɔn, sizhɔ). If dis apin, go na imejensi rum (ETU) wantɛm wantɛm.
- I kin tek sɔm tɛm fɔ fɛn di rayt mɛrɛsin fɔ yu. So peshɛnt ɛn kɔntinyu fɔ tɔk to yu dɔktɔ ɔltɛm. Yu dɔktɔ rɛdi ɔltɛm fɔ ɛp yu.
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