Wi no aw i nɔ izi fɔ fɛt kansa. Na nɔmal tin fɔ fil bad we dɔktɔ dɛn tɔk nyu, kɔmpleks wɔd dɛn lɛk "jin tɛrapi." Bɔt nɔ wɔri. Tide wi go tɔk bɔt wan pan dɛn kayn patikyula tritmɛnt ya. Imajin se yu de yuz yu yon bɔdi in sɛl dɛn, tren dɛn, ɛn sɛn dɛn fɔ pwɛl kansa sɛl dɛn. Na dat dis tritmɛnt we dɛn kɔl Tisagenlecleucel de du. Lɛ wi tɔk bɔt am simpul wan ɛn klia wan.
Wetin na Tisagenlecleucel (KYMRIAH)?
Fɔ tɔk am simpul wan, dis nɔto pil we yu de tek ɔ drɔg we yu kin injɛkt ɔltɛm na yu vein. Tisagenlecleucel na wan jin tɛrapi . I min se yu fɔ tek wan kayn sɛl frɔm yu yon imyun sistɛm, chenj am na lab, ɛn tren am fɔ no ɛn atak di kansa sɛl dɛn.
Fɔ tɔk di kɔrɛkt tin, wi bɔdi gɛt wan kayn fɛt sɛl we dɛn kɔl T-sɛl. Na dɛn sɛl ya de fɛt sik. Insay dis tritmɛnt, dɔktɔ dɛn kin tek sɔm pan dɛn T-sɛl ya na yu bɔdi. afta dat, insay wan lab, dεn de yuz jεnεtik tεknכlכji fכ put tu "spεshal glas" pan dεn T-sεl dεm ya. dat min se dεn de mכdify dεn sεl dεm ya so dat dεn kin no spεshal mak dεm na di sεf fכ di kεnsar sεl dεm. afta dat, milכn pan dεn "superpowered" T-sεl dεm de gro εn injεkt bak insay yu bכdi tru wan vein. Naw dɛn sɛl dɛn ya we dɛn dɔn tren kin go stret to di kansa sɛl dɛn ɛn pwɛl dɛn.
Dɛn kin yuz dis tritmɛnt mɔ fɔ trit sɔm kayn kansa, lɛk akyu lymphoblastic leukemia (ALL) , wan kayn lukimiya, ɛn non-Hodgkin lymphoma .
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu bigin tritmɛnt
Pan ɔl we dis na tritmɛnt we yu de yuz yu yon sɛl, i impɔtant fɔ mek yu tɔk to yu pipul dɛn we de kia fɔ yu bifo yu bigin. Dɛn fɔ mek dɛn no bɔt dɛn tin ya:
- Infεkshכn dεm naw: Tεl wi if yu gεt εni infεkshכn naw, lεk fiva, kכf, kol, כ urinary tract infεkshכn.
- Inflammatory conditions: Tɛl yu dɔktɔ bɔt ɛni inflammatory disɔda ɛnisay na di bɔdi.
- Alɛji: Mek shɔ se yu tɔk bɔt ɛni alɛji we yu gɛt, nɔto jɔs to dis mɛrɛsin, bɔt to ɛni ɔda mɛrɛsin, it, ɔ day.
- Bɛlɛ: If yu gɛt bɛlɛ, yu de tray fɔ gɛt bɛlɛ, ɔ yu gɛt ɛnitin we yu tink se yu gɛt bɛlɛ, tɛl yu dɔktɔ wantɛm wantɛm. Dis rili impɔtant.
- Fɔ gi pikin in mama in bɛlɛ: If yu de gi pikin in mama in bɛlɛ, tɛl di dɔktɔ bak.
Aw yu kin gi dis tritmɛnt?
Dis tritmɛnt kin gɛt sɔm step dɛn ɛn dɛn kin du am ɔnda di klos we wan mɛdikal tim na ɔspitul ɔ spɛshal klinik de kia fɔ am.
1. sεl dεm we de kכlekt: lεk 3-4 wik bifo di tritmεnt, dεn de kכlekt di T-sεl dεm frכm yu bכdi. dis kin bi tru wan prכsεs we dεn k כl lukafεresis . I tan lɛk we pɔsin de gi blɔd. Dɛn kin pul blɔd frɔm wan vein, pas am tru wan spɛshal mashin, we kin sheb di wayt blɔd sɛl dɛn, inklud di T-sɛl dɛn, dɔn dɛn kin put di blɔd we lɛf bak insay yu bɔdi.
2. Sεl trenin: dεn kin sεnd dεn sεl dεm ya we dεn kכlekt na di lab εn tren dεm fכ fεt kεnsar.
3. Infuzhכn: We dεn dכn tren di sεl dεm εn gro, dεn de infuz insay yu bכdi tru wan vein, lεk salin sכlushכn. Dis ɔltin kin apin na di ɔspitul.
Di tin we impɔtant pas ɔl na dat bikɔs dɛn mek dis mɛrɛsin wit yu yon sɛl, na pɔsin in yon tritmɛnt fɔ yu . So, dɛn nɔ go ebul fɔ sheb dis mɛrɛsin wit ɛni ɔda pɔsin.
Tin dɛn we yu fɔ tink bɔt we yu de du tritmɛnt
Yu dɔktɔ dɛn go de wach yu sik gud gud wan we dɛn de du dis tritmɛnt. Yu fɔ no bak bɔt dɛn tin ya.
- Fɔ slip ɛn drayv: Yu kin fil lɛk se yu de slip ɛn yu ed kin tɔn . So , nɔ du ɛnitin we go mek yu maynd de wach, lɛk fɔ drayv ɔ fɔ yuz ebi ebi mashin, te yu no gud gud wan aw dis mɛrɛsin de afɛkt yu.
- Risk fɔ gɛt infɛkshɔn: Dis tritmɛnt kin mek yu bɔdi nɔ ebul fɔ fɛt sik fɔ sɔm tɛm. So tray fɔ de fa frɔm pipul dɛn we sik. If yu gɛt sɔm sayn dɛn lɛk fiva, bɔdi we de at, ɔ trot we de at , kɔl yu dɔktɔ wantɛm wantɛm instead fɔ tek mɛrɛsin fɔ yusɛf.
- Blɔd ɔ ɔgan gi: Nɔ gi blɔd, ɔgan, tisu, sperm, ɔ eg (oocytes) we yu de tek dis tritmɛnt ɛn fɔ sɔm tɛm afta dat.
- Bɛlɛ (I Impɔtant): Nɔ gɛt bɛlɛ fɔ ɛni rizin we yu de tek dis mɛrɛsin. Dɔn bak, if yu de plan fɔ bɔn pikin ɔ yu tink se yu gɛt bɛlɛ, yu fɔ tɛl yu dɔktɔ wantɛm wantɛm. Dis mɛrɛsin kin rili ambɔg di pikin we nɔ bɔn yet.
- Ɔda mɛrɛsin dɛn: Tɛl yu dɔktɔ bɔt ɛni ɔda mɛrɛsin we yu de tek (inklud vaytamɛn ɛn ɛbul mɛrɛsin). Layf vaysin nɔ de mɔ dis tɛm.
- Sɔntin yu nɔ plan:Dɛn kin gi dis na ɔspitul, so yu nɔ go de tek bɔku mɛrɛsin. Bɔt if ɛnitin apin, tɛl di mɛdikal tim wantɛm wantɛm. If nid de, dɛn go rifer yu to di Imejɛnsi Tritmɛnt Yunit (ETU) . If yu tink se ɛni pɔyzin de, yu kin kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital .
Sɔm sayd ɛfɛkt dɛn we dis mɛrɛsin kin gɛt
Lɛk ɔl mɛrɛsin, dis wan kin gɛt sayd ɛfɛkt. Sɔm pan dɛn tin ya fɔ ripɔt wantɛm wantɛm, ɛn ɔda wan dɛn nɔ kin rili siriɔs. Si di tebul we de dɔŋ ya.
| Klasifikɛshɔn fɔ di sayd ɛfɛkt dɛn | |
|---|---|
| Tin dɛn fɔ ripɔt to yu dɔktɔ ɔ di mɛdikal tim wantɛm wantɛm | |
| Alɛji dɛn we pɔsin kin gɛt | Skin rash, it, swel na di fes, lip ɔ tong. |
| I nɔ izi fɔ blo | I nɔ kin izi fɔ yu fɔ blo. |
| Di chenj dɛn we pɔsin kin gɛt na in maynd | Kɔnfyushɔn, at fɔ tɔk ɔ ɔndastand. |
| Di sayn dɛn we de sho se di blɔd sɛl dɛn nɔ bɔku | Di sayn dɛm fɔ infekshɔn: fiva, kol, trot we de at. Sayn dɛm fɔ blɔd: brus, rɛd spat na di skin, blak stɔl, blɔd na di urine. Lɔw rɛd blɔd sɛl kɔnt: taya pasmak, fɔdɔm, paleness. |
| Ɔda siriɔs sayn dɛn | Daya, we yu nɔ de balans, we yu de fil pen na yu mɔsul ɔ yu jɔyn, yu nɔ de fil fayn, yu de vɔmit, yu de fil lɛk yu blɔd prɛshɔn, yu blɔd prɛshɔn we de sho se yu nɔ gɛt bɛtɛ blɔd (diziz, yu fɔdɔm). |
| If i kɔntinyu ɔ i de mɔna yu, tɛl yu dɔktɔ. | |
| Kɔmɔn sayd ɛfɛkt dɛn | Kɔnstipɛshɔn, nɔr kin want fɔ it, ed kin at, bɛlɛ kin pen, yu leg ɛn fut kin swel. |
Dis list nɔ de inklud ɔl di sayd ɛfɛkt dɛn we pɔsin kin gɛt. If yu gɛt ɛnitin we nɔ kɔmɔn, tɔk to yu dɔktɔ bɔt am.
Mɛsej we dɛn kin kɛr go na os
- Tisagenlecleucel na pɔsnalayz jin tɛrapi we de yuz yu yon imyun sɛl fɔ trit kansa.
- Dis na spɛshal tritmɛnt we dɛn kin gi na ɔspitul, we dɛn kin yuz fɔ sik dɛn we gɛt siriɔs lukimiya ɛn limfoma.
- I impɔtant fɔ mek yu tɛl yu dɔktɔ ɔl yu wɛlbɔdi infɔmeshɔn (infɛkshɔn, alɛji, bɛlɛ) bifo yu bigin tritmɛnt.
- We yu de trit yu, fɔ no mɔ bɔt di sayn dɛn we de sho se yu gɛt di sik (fiva, kɔf). If dɛn kayn sayn dɛn de apin, go to dɔktɔ wantɛm wantɛm.
- As yu kin fil lɛk se yu de slip, nɔ fɔ drayv ɛn du tin dɛn we yu nid fɔ pe atɛnshɔn to te yu wɛl ɔl.
- Nɔ gɛt bɛlɛ ɔltogɛda we yu de trit yu. Dis rili impɔtant.
- Nɔr frayd fɔ tɔk to yu mɛdikal tim bɔt ɛnitin wae de mɔna yu ɔr dawt yu. Dɛn de de fɔ ɛp yu.
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