Lɛ wi lan bɔt Zollinger-Ellison Syndrome insay simpul wɔd dɛn.

Yu dɔn ɛva yɛri bɔt Zollinger-Ellison Syndrome ? I kin tan lɛk se na strenj nem, bɔt na sik we kin afɛkt wi insay ɛn na sɔntin we wi fɔ wɔri bɔt. I kin mek wi gɛt siriɔs ɔlsa na di bɛlɛ ɛn dayarɛa we nɔ de dɔn bikɔs ɔf di ɔva prodyuz ɔf asid na wi bɛlɛ. So, lɛ wi tɔk bɔt am smɔl mɔ tide, nɔto so?

Wetin rili na Zollinger-Ellison Syndrome?

Fɔ tɔk am simpul wan, di men tin we kin mek dis sik we dɛn kɔl Zollinger-Ellison Syndrome (ZES) na wan kayn smɔl smɔl tɔŋ we kin kam na wi bɔdi, mɔ na di pankrias ɔ di ɔp pat na di smɔl intestin (duodenum). Wi kin kɔl dɛn tumbu ya gastrinomas . dis na rili wan kayn nyuroεndokrin tכmכro dεm .

Naw luk, dɛn gastrinoma ya de mek wan ɔmon we dɛn kɔl gastrin . dis gastrin כmon na in de signal wi bεlε fכ "Okay, stat fכ mek asid naw." So, we dεn tכmכro dεm ya de mek tu mכch gastrin כmon, di bεlε de mek tu mכch asid bak. Jɔs tink bɔt am lɛk pɔt we de lik wata we yu nɔ lɔk am tayt, wi bɛlɛ asid de bɔku we wi nɔ ebul fɔ kɔntrol. dis εksyכs asid na in de mek prכblεm lεk bεlε כlsa εn asid rεfluks.

I kin wɔri smɔl fɔ no se lɛk 60% pan dɛn gastrinomas ya kin gɛt kansa . Bɔt nɔ wɔri, lɛk ɔl ɔda tin, tritmɛnt de fɔ dis bak. Sɔntɛnde, dɔktɔ dɛn kin kɔl dis sik bak "pancreatic ulcerogenic tumor syndrome."

Wetin na di sayn dɛm fɔ dis? Aw wi de fil?

Sɔmtɛm, Zollinger-Ellison syndrome (ZES) nɔr kin kɔz ɛni sayn. Bɔt we di sayn dɛn kin apin, dɛn kin bi:

• Bɛlɛ de bɔn ɔ pen: Yu kin fil bɔn insay yu bɛlɛ, ɔ lɛk se sɔntin de it yu. Dis kin bi bikɔs ɔf di asid we pasmak.
• Blɔd we de na di vɔmit ɔ blɔd we de na di stɔl: Dis kin apin we blɔd de kɔmɔt na di wund dɛn we de insay di intestinal (gastrointestinal bleeding).
• Taya ɛn wik: As wi bin dɔn tɔk, bikɔs yu blɔd de lɔs, yu kin fil taya ɛn wik bikɔs yu nɔ gɛt blɔd.
• Stɔl we gɛt ɔyl ɛn we de flɔt: Sɔm pipul dɛn kin notis se dɛn stɔl chenj, we kin gɛt mɔ ɔyl.
• At bɔn: Fɔ tɔk di kɔrɛkt tin, na we pɔsin de bɔn na di chɛst we asid de kam ɔp di εsophagus.
• Bloating, indigestion: Dis kin fil mɔ, mɔ afta yu it it we gɛt fat.
• Di it nɔ de te.
• Nɔs ɛn vɔmit.
• Fɔ bi tin fɔ no rizin.

Di kayn we aw dɛn sik ya kin tranga kin dipen pan di sayz ɛn di nɔmba fɔ di gastrinomas. di big tכmכro dεm de mek mכr gastrin, we de mek di bεlε de mek mכr asid. Dis kin mek di sayn dɛm fɔ peptik ɔlsa sik wɔs.

Mɛmba se sɔntɛnde, dɛn tumbu ya kin go na di liva, ɛn dis kin mek pɔsin gɛt kansa na di liva. If dat apin, sɔm sayn dɛn lɛk fɔ it, fɔ yɔlɔ na yu yay wayt, ɛn fɔ yɔlɔ na yu skin (jaundice) kin apin bak.

Wetin mek wi gɛt dis kayn tin? Wetin na di rizin dɛn?

Bɔrku tɛm, Zollinger-Ellison Syndrome (ZES) kin apun wan wan tɛm , dat min se i nɔ kin izi fɔ no di rayt tin we kin mek i apin.

Bɔt dɛn dɔn si se lɛk 25% pan di pipul dɛn we gɛt dis sik gɛt wan sik we dɛn kɔl MEN Type 1 (Multiple Endocrine Neoplasia Type 1) . MEN Tayp 1 na wan rare, inhɛrit kכndyushכn we tכmכro kin divεlכp insay mכltipכl εndokrin gland dεm na wi bכdi.

Us prɔblɛm dɛn kin kam wit dis sik? A fɔ wɔri?

Yɛs, Zollinger-Ellison Syndrome (ZES) na wan sik we kin mek pɔsin in layf de pan denja sɔntɛnde . fכ egzampl, if gastrinoma blok di כp pat pan di sכmכl intestכn (duodenum), i kin bכs. I kin skata bak to di liva. Siriɔs blɔd we de kɔmɔt na di bɛlɛ kin apin bikɔs ɔf di asid we pasmak na di bɛlɛ.

Bɔt, nɔ panik we yu yɛri dɛn tin ya. If dɛn no di sik kwik kwik wan ɛn trit am fayn, dɛn kin ebul fɔ avɔyd dɛn prɔblɛm ya bɔku tɛm.

Aw dɔktɔ dɛn kin no bɔt dis sik? (Diagnosis) .

If yu gɛt dɛn sik ya, dɔktɔ go fɔs chɛk yu, aks yu bɔt yu sik ɛn if ɛnibɔdi na yu famili dɔn gɛt dɛn sik ya. Dɔn, dɛn kin du tɛst dɛn lɛk:

• Blɔd tɛst: Dɛn tin ya kin chɛk if yu blɔd gastrin ɔmon lɛvɛl tu ay (hypergastrinemia).
• Imej tɛst: Dɛn kin du CT skan ɔ MRI skan fɔ si if gastrinoma tumor dɛn de na di pankrias ɔ duodenum.
• Bɛlɛ asid tɛst: Insay dis tɛst, dɔktɔ kin put smɔl tiub insay di bɛlɛ tru di nos ɔ mɔt ɛn tek wan sɛmpul pan di asid de.

If dɛn fɔs tɛst ya sho se di tumbu dɛn de, di dɔktɔ kin du sɔm ɔda tɛst dɛn:

• Ɛndoskopi: Insay dis tɛst, dɛn kin put wan smɔl tiub we gɛt kamɛra we dɛn tay tru di mɔt ɛn dɛn kin chɛk di εsophagus, bɛlɛ, ɔp pat pan di smɔl intestin (duodenum), ɛn pankrias.
• εndoskopik כltra saund: Dis na we dεn kכmbayn כltra saund εn εndoskopi. I kin mek pikchɔ dɛn we klia.
• ERCP (Endoscopic Retrograde Cholangiopancreatography): Dis na spɛshal skan bak. i de luk insay di bayl dakt dεm εn di pankrεas dakt dεm.
• Fayn-nidul aspireshɔn: If tumbu de, dɛn kin yuz dis we fɔ tek smɔl pat pan am ɛn tɛst am fɔ si if i gɛt kansa sɛl (bayopsi).

Wetin na di tritmɛnt dɛm fɔ dis? (Tritmɛnt)

Di tritmɛnt we dɛn kin pik kin dipen pan aw yu sik dɛn bad ɛn if di gastrinoma na kansa. Tri men kayn tritmɛnt de:

1. Mɛrɛsin:

• Di men mɛrɛsin we dɛn kin gi bɔku tɛm na di proton pump inhibitors (PPI) . Dɛn mɛrɛsin ya de wok bay we dɛn de ridyus di asid we de kɔmɔt na di bɛlɛ. Fɔ tɔk am simpul wan, dɛn kin kɔntrol di asid we pasmak we dɛn kin mek.

2. Ɔpreshɔn:

• Yu dɔktɔ go tɛl yu fɔ du ɔpreshɔn fɔ pul di tumbu. Bɔku kayn ɔpreshɔn dɛn de:
• duodenectomy: dεn kin pul di tכmכro tru wan sכm sכm pat na di כp pat pan di sכmכl intestin (duodenum).
• Gastrectomy: Dɛn kin pul wan pat ɔ ɔl di bɛlɛ.
• Liva ɔpreshɔn: If tumbu de na di liva, dɛn kin pul am.
• Pancreatectomy: Dɛn kin pul wan pat ɔ ɔl di pankrias.
• tכmכro nyukliashכn: If tכmכro dεm de na di ed pan di pankrias, na dεn wan dεm nכmכ dεn kin tek tεm pul.

3. Tɛrapi fɔ kansa:

• If di tumbu gɛt kansa, yu dɔktɔ kin tɛl yu fɔ gi yu tritmɛnt lɛk kemotɛrapi . Dɛn tritmɛnt ya kin ɛp fɔ ridyus di sayn dɛm ɛn slo fɔ mek di tumbu skata.

Yu tink se tritmɛnt go ebul fɔ mɛn am kpatakpata?

If dɛn kin pul wan kansa gastrinoma kpatakpata wit ɔpreshɔn, di sik kin wɛl kpatakpata . Bɔt dis nid fɔ pul ɔl di kansa sɛl dɛn na di bɔdi. Ivin if di ɔpreshɔn nɔ wok fayn, bɔku tɛm yu go gɛt fɔ tek mɛrɛsin fɔ kɔntrol di asid na yu bɛlɛ fɔ di res ɔf yu layf.

If a gɛt dis sik, wetin a fɔ ɛkspɛkt? (Prɔgnosis) .

di prognosis fכ yu wit dis kכndyushכn dipכnt pan di kayn tכmכro. Gastrinomas we nɔ gɛt kansa nɔ kin mek pɔsin in layf de pan denja. Bɔt yu go nid fɔ kɔntinyu fɔ gɛt tritmɛnt fɔ kɔntrol di asid we de na yu bɛlɛ.

Bɔt di tin kin chenj if yu gɛt kansa tumbu. If na so i bi, yu go nid fɔ gɛt ɔpreshɔn ɛn fɔ fala di tritmɛnt fɔ kansa.

Di rεt wae de liv fɔ pipul dɛm wae gɛt Zollinger-Ellison syndrome (ZES) kin difrɛn. di data sho se afta dεn dכn כpכt כl di gastrinomas, pas 90% pan di pipul dεm de liv fכ 5 to 10 ia . כltu, if dεn nכ kin pul כl di tכmכro dεm, di 5 ia sכvayv rεt de dכn to 43%. I impɔtant fɔ mɛmba se dɛn tin ya na jɔs statystik. If yu gɛt dis sik, tɔk to yu dɔktɔ bɔt wetin yu go ebul fɔ ɛkspɛkt.

Aw a fɔ kia fɔ misɛf? Wetin a go du?

I dipen pan yu kɔndishɔn. Bɔrku pipul dɛn kin gɛt fɔ tek mɛrɛsin fɔ ridyus dɛn bɛlɛ asid fɔ di res ɔf dɛn layf. Di sik we dɛn kɔl Zollinger-Ellison syndrome (ZES) kin kam wit di sik we dɛn kɔl gastrinomas. Bɔku pan dɛn tumbu ya kin gɛt kansa. So, if yu dɔn gɛt kansa tumbu, yu nid fɔ kɔntinyu fɔ go to yu dɔktɔ fɔ mek dɛn go kia fɔ yu fɔ si if dɛn dɔn kam bak.

Ustɛm a fɔ go to dɔktɔ bak?

Afta yu dɔn gɛt tritmɛnt, if yu Zollinger-Ellison Syndrome (ZES) simptom dɛn wɔs ɔr nyu sayn dɛm kam, yu fɔ go to dɔktɔ wantɛm wantɛm.

We yu kam fɔ no se yu gɛt dis kayn sik we nɔ bɔku, yu go sɔprayz ɛn fred smɔl. I kin tranga fɔ yɛri sɔntin lɛk dis wantɛm wantɛm, pan ɔl we yu nɔ go gɛt ɛni sayn. Yu kin gɛt bɔku kwɛstyɔn bɔt aw ZES go afɛkt yu. Di ansa to dɛn kwɛstyɔn dɛn de kin difrɛn bad bad wan fɔ di tin dɛn we de apin to yu.

Di tin we impɔtant pas ɔl na fɔ tɔk bɔt ɔl yu kwɛstyɔn ɛn dawt dɛn wit di dɔktɔ. Dɛn go ɛksplen ɔltin to yu ɛn gi yu di sɔpɔt we yu nid.

Mɛsej we dɛn kin kɛr go na os:

Okay, so lɛ wi mɛmba sɔm pan di impɔtant pɔynt dɛn frɔm wetin wi dɔn tɔk bɔt:

• Zollinger-Ellison Syndrome (ZES) na wan sik we kin kam wit wan tumbu we dɛn kɔl gastrinoma, we kin mek yu bɛlɛ ɔlsa ɛn dayarɛa bikɔs ɔf di bɛlɛ asid we pasmak.
• Sɔm sayn dɛm lɛk bɛlɛ pen, blɔd we yu de vɔmit, chɛst pen, ɛn we yu de lɔs in wet kin apin.
• Bɔku pan dɛn tumbu ya kin gɛt kansa.
• Dɛn kin no dis sik tru tɛst lɛk blɔd tɛst, skan, ɛn ɛndoskopi.
• Di tritmɛnt inklud mɛrɛsin (PPI), ɔpreshɔn, ɛn kemotɛrapi.
• If yu no am kwik kwik wan ɛn trit yu, dat kin mek yu nɔ gɛt prɔblɛm ɛn i kin mek yu wɛl.
• If yu gɛt dis sik, fala yu dɔktɔ in instrɔkshɔn dɛn gud gud wan, du tɛst di rayt tɛm, ɛn tɔk to yu dɔktɔ we yu nɔ fɔ ol ɛnitin.

A op se dis infɔmeshɔn go yusful to yu. Stay wit wɛlbɔdi!

` Zollinger-Ellison Syndrome, gastrinoma, gastric acid, peptik ɔlsa, dayarɛa, ɔmon, kansa