Oluusi ffe oba omuntu waffe tulina okuyita mu bujjanjabi obw’amaanyi ng’okusimbuliza obutoffaali obusibuka mu mubiri olw’obulwadde obw’amaanyi nga kookolo. Wadde ng’obujjanjabi obwo buba buwanguzi, oluusi buyinza okuleeta ebizibu ebimu. Leero twogera ku ddagala ery’enjawulo eriweebwa okujjanjaba ekizibu eky’amaanyi bwe kiti, naye nga tekitera kubaawo. Eyo ye ddagala erigema eriyitibwa Defibrotide.
Defibrotide kye ki era akozesebwa ki?
Mu ngeri ennyangu, Defibrotide mpiso ya njawulo. Kikozesebwa okujjanjaba embeera ey’amaanyi ebaawo oluvannyuma lw’okusimbuliza obutoffaali obusibuka, olw’okuzibikira emisuwa emitono ennyo mu kibumba . Mu by’obujjanjabi, embeera eno eyitibwa obulwadde obuziyiza emisuwa (VOD) oba Sinusoidal Obstruction Syndrome (SOS).
Teebereza nti waliwo obusuwa obutonotono obukulukuta mu kibumba kyaffe. Oluvannyuma lw’obujjanjabi obw’amaanyi ng’okusimbuliza obutoffaali obusibuka, oluusi emisuwa gino giyinza okuzibikira. Kino kiyinza okukosa ennyo enkola y’ekibumba. Mu kiseera ekyo, eddagala eriyitibwa Defibrotide liyamba okuddamu okuggulawo emisuwa gino egyazibiddwa n’okukendeeza ku kwonooneka kw’ekibumba.
Ekikulu, lino si ddagala ly’osobola okutwala awaka. Kiweebwa ng’okufuyira mu ddwaaliro, nga kilabirirwa abasawo ne ba nurse mu bujjuvu .
Ebintu by’olina okubuulira omusawo nga tonnatandika bujjanjabi
Nga ggwe oba omulwadde wo tonnatandika bujjanjabi bwa Defibrotide, kikulu nnyo okubuulira omusawo wo ku byafaayo byo byonna eby’obulamu. Okusingira ddala, olina okumanya obukwakkulizo buno wammanga:
| Embeera gy’olina okuloopa | Lwaki bwe kityo bwe kiri? |
|---|---|
| Bw’oba olina obuzibu bw’okuvaamu omusaayi. | Kino kikulu nnyo naddala bw’oba olina dda embeera, kuba eddagala lya defibrotide liyinza okwongera ku bulabe bw’okuvaamu omusaayi. |
| Bw’oba omira eddagala eddala erigonza omusaayi oba okuziyiza omusaayi okuzimba (blood thinners). | Kino omusawo alina okukimanya, kubanga okukozesa eddagala lino awamu kiyinza okuvaamu omusaayi omungi. |
| Bw’oba olina allergy eri Defibrotide oba eddagala eddala lyonna, emmere oba langi. | Kino kyetaagisa nnyo okuziyiza alergy. |
| Bw’oba oli lubuto, ng’ogezaako okufuna olubuto, oba ng’oyonsa. | Olina okuteesa n’omusawo wo engeri eddagala lino gye linaakwata ku maama n’omwana. |
Eddagala eritalina kukozesebwa na Defibrotide
Okwegendereza: Bw’oba omira Defibrotide, eddagala eddala eriziyiza omusaayi okuzimba oba okugonza omusaayi, nga Heparin ne Alteplase , liyinza okuvaamu omusaayi omungi . N’olwekyo, kakasa nti otegeeza omusawo wo ku ddagala lyonna ly’omira, omuli eddagala ly’ebimera, vitamiini n’ebirungo ebiyamba omubiri.
Ebiyinza okuvaamu ebizibu
Okufaananako n’eddagala lyonna, Defibrotide asobola okuleeta ebizibu ebimu. Ebimu ku bino biyinza okuba eby’amaanyi, n’olwekyo kikulu okubimanya n’okutegeeza ttiimu y’abasawo mu bwangu singa ofuna obubonero bwonna.
| Side effect | Okunnyonnyola |
|---|---|
| Bw’oba olina obubonero buno, tegeeza omusawo oba nnansi wo mu bwangu. | |
| Ebintu Ebiva mu Allergy | Okusiiyibwa ku lususu, okusiiwa, okuzimba mu maaso, emimwa oba olulimi. |
| Obubonero bw’okuvaamu omusaayi | Omusaayi mu musulo oba omusulo omuddugavu, omusulo omumyufu oba ogwa kitaka omuddugavu, okusesema ekintu ekiringa ebikuta bya kaawa, amabala amamyufu ku lususu, okuvaamu omusaayi ogutali gwa bulijjo okuva mu maaso, ennyindo oba ennyindo. |
| Obubonero bwa Puleesa Entono | Okuziyira, okulaba obubi, okuzirika, okuwulira ng’okooye oba nga munafu mu ngeri etaali ya bulijjo. |
| Obubonero bw’Obulwadde | Omusujja oba okuwulira ennyonta, okusesema, okulumwa emimiro. |
| Bino ebiseera ebisinga tebiba bya maanyi, naye bwe bisigala, tegeeza omusawo wo. | |
| Embiro | Okuzimba omubiri. |
| Ekikeeto | Okuwulira ng’oyagala okusesema. |
| Okusesema | Okusesema. |
Kiki eky’okukola singa ddoozi yeeyongera (overdose)?
Okuva eddagala lino bwe liweebwa mu ddwaaliro, wansi w’obulabirizi bw’abasawo, mu bungi obusinga obutuufu, emikisa gy’okulinywa ekisukkiridde mitono nnyo. Ttiimu y’abasawo bulijjo bagifaako. Naye singa wabaawo okwekengera kwonna ku kintu ng’ekyo, omusawo oba nnansi mu ddwaaliro ajja kukola ebyetaagisa. Ebiseera ebisinga, ekifo ekitongole eky’okufuna amagezi mu nsi yaffe singa wabaawo obutwa bwonna kye kifo kya National Poisons Information Center mu ddwaaliro lya Colombo National Hospital . Naye singa wabaawo ekintu nga kino ekibaawo mu ddwaaliro, ekitongole ky’eddwaaliro ekikola ku bujjanjabi obw’amangu (ETU) kikola amangu ddala.
Obubaka Obutwala Awaka
- Defibrotide mpiso ya njawulo eweebwa mu musuwa ogujjanjaba ekizibu ky’ekibumba eky’amaanyi ekiyinza okubaawo oluvannyuma lw’okusimbuliza obutoffaali obusibuka.
- Kikulu nnyo okubuulira omusawo wo ku ddagala eddala lyonna ly’omira naddala ery’okugonza omusaayi, n’embeera zonna ez’obujjanjabi z’olina.
- Obulabe obusinga mu kiseera ky'obujjanjabi buno kwe kuvaamu omusaayi . N’olwekyo, bw’olaba n’akabonero akatono akalaga nti avaamu omusaayi, tegeeza abasawo mu bwangu.
- Eddagala lino liweebwa mu ddwaaliro lyokka era si ddagala lya kukozesebwa waka.
- Bw’oba olina ekibuuzo kyonna oba ekikweraliikiriza ku ddagala oba obujjanjabi buno, tolwawo kubuuza musawo wo oba abakozi ba ba nnamusa.
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