Obusimu obw’ekyama obufuga obuzito: Byonna bikwata ku Leptin

Wali weebuuzizzaako engeri gy’owulira ng’ojjudde? Bwe tulya, oluvannyuma lw'akaseera tuwulira "Okay, ekyo kimala." Kiki ekireeta enneewulira eno? Kale lwaki abantu abamu tebawulirangako kukkuta ne bwe balya batya? Leptin ye muzannyi omukulu emabega wa bino byonna. Buno busimu bukulu nnyo mu kufuga obuzito bw’omubiri gwaffe. Ka twogere ku nsonga eno mu ngeri ennyangu era entuufu leero.

Leptin kye ki, mu ngeri ennyangu?

Mu ngeri ennyangu, leptin busimu obukolebwa obutoffaali bw’amasavu mu mubiri gwo (adipose tissue). Era kimanyiddwa nga "satiety hormone." Omulimu gwayo omukulu kwe kusindika akabonero ku bwongo bwo akagamba nti, "Okay, olina amaanyi agamala, lekera awo okulya." Eno y’engeri leptin gy’ayamba okukuuma obuzito bw’omubiri obutebenkevu mu bbanga eggwanvu.

Bannasayansi baazuula obusimu bwa leptin mu 1994, ekitegeeza nti wakyaliwo okunoonyereza kungi okukolebwa ku nsonga eno. Akakwate ka leptin si ku kukendeeza ku buzito bwokka, wabula n’endwadde ng’obulwadde bwa Alzheimer, obulamu bw’okuzaala, n’obutazaala mu kiseera kino kanoonyezebwa.

Bw'owulira ekigambo "okufuga obuzito," oyinza okulowooza nti, "Oh... tusobole okufuga leptin ne tugejja." Naye ekituufu kiri nti okufuga obusimu buno mu ngeri gye twagala si kyangu nga bwe tulowooza.

Leptin ekola etya mu mubiri gwaffe?

Omulimu omukulu ogwa Leptin kwe kuyamba okukuuma obuzito bw’omubiri gwaffe. Kwe kugamba, okuleetawo enzikiriziganya ey’ekiseera ekiwanvu wakati w’obungi bw’emmere gye tulya n’amaanyi omubiri gwaffe ge gusaasaanya. Leptin atulemesa okuwulira enjala mu ngeri eteetaagisa. Kiyamba okutangira omubiri okulaga enjala nga tegwetaaga maanyi (calories).

Leptin okusinga ekola nga ekosa ekitundu ky’obwongo bwaffe ekiyitibwa hypothalamus. Wabula waliwo ebirungo ebikwatagana mu bitundu by’omubiri ebirala ebiddamu ku leptin.

Ekisinga obukulu, leptin tefuga njala yaffe okuva ku mmere emu okudda ku ndala. Wabula ekola okufuga emmere gy’olya n’amaanyi g’esaasaanya mu bbanga eggwanvu, okukuuma obuzito bw’omubiri nga tebukyukakyuka.

Teebereza ng’ogezaako okugejja. Amasavu mu mubiri gwo bwe gakendeera, leptin nayo ekendeera. Kino kiweereza akabonero ku bwongo bwo nti enjala ekuluma. Kino kikuleetera okuwulira enjala ennyo n’okuba n’okwegomba. Kino kiyinza okukuleetera okulya ennyo nga tokitegedde. Eno y’emu ku nsonga lwaki kizibu nnyo okugejja.

Emiwendo gya leptin gifugibwa gitya?

Leptin ekolebwa era n’efulumizibwa mu musaayi okuva mu bitundu by’amasavu ebyeru mu mibiri gyaffe. N’olwekyo, obungi bwa leptin mu musaayi gwo bukwatagana butereevu n’obungi bw’amasavu mu mubiri gwo.

• Bw’oba ​​olina amasavu agasukkiridde mu mubiri:Emiwendo gya leptin giri waggulu.
• Singa amasavu mu mubiri gaba matono: emiwendo gya leptin giba mitono.

Ekiseera bwe kigenda kiyitawo, singa amasavu mu mubiri gwo geeyongera, leptin geeyongera ate singa amasavu mu mubiri gwo gakendeera, leptin gakendeera.

Kiki ekibaawo singa emiwendo gya leptin giyitiridde? - Okuziyiza Leptin

Omuntu omugejjo alina amasavu mangi mu mubiri gwe. N’ekyavaamu, omuwendo gwa leptin mu musaayi gwabwe nagwo guli waggulu nnyo. Embeera eno tugiyita hyperleptinemia .

Kati oyinza okuba ng'olowooza nti, "Singa leptin ebeera mungi, wandibadde owulira ng'ojjudde, kale wandibadde ofuga okulya kwo?" Naye ekintu ekikontana n’ekyo kituufu. Emiwendo gya leptin mu mubiri bwe giba mingi okumala ebbanga eddene, obwongo butandika obutaddamu ku kabonero ako aka leptin. Kiba ng’omuntu atuleekaana buli kiseera ne tufuuka abazirika oluvannyuma lw’akaseera. Kino kiyitibwa okuziyiza leptin .

Kiki ekibaawo olw’ensonga eno?

1. Obutajjula: Wadde olina amasavu agamala mu mubiri, obwongo bwo bulowooza nti enjala okyalina. Kale osigala ng’olya.

2. Omubiri gugenda mu "starvation mode": Olw'okuba obwongo tebufuna signal ya leptin, obwongo bulowooza nti omubiri tegulina maanyi gamala era nti tufa enjala. Kale, okukuuma amaanyi, omutindo gw’omubiri oguyitibwa basal metabolic rate (BMR) gukendeera. Kino kitegeeza nti omuwendo gwa kalori z’oyokya ng’otudde butudde bukendeera.

Mu ngeri eno, okuziyiza leptin, ku ludda olumu, kwongera enjala n’okwongera ku bungi bw’emmere eriibwa, ate ku ludda olulala, omutindo omubiri gwe gwokya kalori gukendeera. Ebintu bino ebibiri bwe bikwatagana, ekivaamu kweyongera okugejja.

Obubonero buno buyinza okuva ku bintu ebirala, n’olwekyo bw’oba ​​ofuna obubonero buno, kirungi okwogera n’omusawo wo .

Kiki ekibaawo singa emiwendo gya leptin gikendeera?

Obutabeera na leptin mbeera etali ya bulijjo nnyo . Kitera okubaawo n'embeera y'obuzaale eyitibwa congenital leptin deficiency . Omuntu alina embeera eno alina embeera ng’obutoffaali bwe obw’amasavu tebusobola kukola leptin.

Leptin bw’aba taliiwo, omubiri gulowooza nti mu mubiri temuli masavu. Kino kiraga nti obwongo bulumwa enjala era nga tebusobola kugifuga. N’ekyavaamu, abaana abato abalina embeera eno baba n’okwagala okulya okutafugibwa. N’ekyavaamu, bagejja nnyo (omugejjo ogw’ekika kya III) ku myaka emito ennyo era bafuna okulwawo okutuuka mu myaka gy’obuvubuka.

Omuwendo gwa leptin gusobola okupimibwa mu musaayi?

Yee, okukebera omusaayi okwangu kusobola okupima emiwendo gya leptin. Kyokka kino si kwekebejja abasawo kwe batera okulagira. Kikolebwa mu mbeera ez’enjawulo zokka. Okugeza nga:

• Singa omwana omuto ennyo aba mugejjo nnyo.
• Singa omuntu omugejjo asigala ng’alina enjala etayinza kufugibwa.

Mu budde obutuufu, emiwendo gya leptin omulamu giyinza okuva ku:

• Abakyala: 0.5 - 15.2 ng/mL (nanograms buli mililita) .
• Ekisajja: 0.5 - 12.5 ng/mL

Emiwendo gino giyinza okwawukana katono okuva ku laabu okudda ku ndala, n’olwekyo bw’oba ​​olina okubuusabuusa kwonna ku miwendo egiri mu lipoota yo, buuza omusawo wo .

Tutereeza tutya emiwendo gya leptin?

Mazima ddala tewali ngeri yonna gy’oyinza kwongera ku muwendo gwa leptin mu ngeri ey’ekikugu okukendeeza ku njala, kubanga emiwendo gya leptin gikwatagana butereevu n’obungi bw’amasavu mu mubiri gwo.

Wabula waliwo ebintu ebiwerako ebiyinza okuyamba ku nkola ya leptin n’okutebenkeza obusimu obulala:

1. Otulo otumala: Okunoonyereza okumu kwazudde nti obuteebaka kyongera ku busimu bw’enjala obuyitibwa ghrelin ate ne bukendeeza ku busimu bw’okukkuta obusimu obuyitibwa leptin. N’olwekyo, okufuna otulo otulungi era ekimala buli lunaku kikulu nnyo eri bbalansi y’obusimu.

2. Lya emmere ennungi: Okunoonyereza okumu kulaga nti ebirungo ebiyitibwa triglycerides ebingi, ekika ky’amasavu mu musaayi, bisobola okulemesa leptin okutuuka ku bwongo. Wadde nga wakyaliwo endowooza ez’enjawulo ku nsonga eno, bulijjo kirungi okulya emmere ennungi omuli enva endiirwa, ebibala, ebiwuziwuzi, puloteyina ennungi, n’amasavu amalungi, ate ng’okendeeza ku ssukaali, akawunga, n’emmere erongooseddwa .

3. Dduyiro buli kiseera: Okunoonyereza kulaga nti dduyiro asobola okuyamba okukendeeza ku buziyiza bwa leptin. Kwe kugamba, dduyiro asobola okulongoosa okuwuliziganya kwa leptin mu bwongo.

Bw’oba ​​weeraliikirira omugejjo gwo, oba nga weetaaga okulambika ku ngeri y’okugejja mu ngeri ennungi, kirungi okwogera n’omusawo wo . Bwe kiba kyetaagisa, ayinza okukusindika ew’omusawo w’endwadde z’omu lubuto.