Obutoffaali bwo obumyufu bugaziwa? (Macrocytosis) - Ka tuzuule ku nsonga eno!

Wali otunuulidde lipoota y’okukebera omusaayi n’olaba ng’obutoffaali bwo obumyufu bunene okusinga obwa bulijjo (obutoffaali obumyufu obugaziye)? Oba omusawo wo akubuuliddeko ku mbeera eyitibwa “Macrocytosis”? Kino kiyinza okuwulikika ng’ekitiisa katono, naye tofaayo. Macrocytosis si bulwadde, nkyukakyuka yokka mu butoffaali obumyufu.

Macrocytosis kye ki?

Mu ngeri ennyangu, Macrocytosis kitegeeza nti obutoffaali bwo obumyufu bunene okusinga obwa bulijjo. Kino tekitwalibwa ng’obulwadde, naye kiyinza okuba akabonero akalaga nti waliwo ekikyamu ku mubiri gwaffe. Kino kimanyibwa ng’olina omusaayi mu bujjuvu (CBC)/ Full Blood Count ( FBC ). Ebiseera ebisinga, abasawo bakola okukebera kuno okwa `CBC` okulaba engeri obutoffaali bw'omubiri gwaffe gye bukolamu n'engeri gye bulamu obulungi.

Lipoota ya `CBC` erina omuwendo oguyitibwa `MCV (Mean Corpuscular Volume)`. Kino kipimo ky’obunene bw’obutoffaali bwo obumyufu obwa wakati. Singa omuwendo gw`omuntu omukulu ogwa `MCV` gusukka femtoliters 100 (`100 fL`), embeera eyo tugiyita Macrocytosis.

Ebiseera ebisinga, kino si kizibu kya maanyi. Kyokka oluusi obutoffaali buno obumyufu obugaziye buyinza obutafuna biriisa bye byetaaga. Olwo, obutoffaali obwo tebusobola kukola mulimu gwabwo omukulu, kwe kutambuza omukka gwa oxygen mu mubiri gwonna. Embeera eno eyitibwa `Macrocytic Anemia` . Singa `Macrocytic Anemia` tejjanjabibwa bulungi, kiyinza okuvaako obuzibu obw'amaanyi mu bulamu.

Embeera eno ya bulijjo etya?

Mu kugeraageranya, wakati wa 2% ne 4% ku bantu b’ensi yonna balina obulwadde bwa Macrocytosis. Abantu bano abasinga obungi, nga 60%, balina obulwadde bwa Macrocytosis wamu n’okubulwa omusaayi.

Wabula obulwadde bwa macrocytosis obutaliimu kukendeera mu musaayi businga kubeera mu baana abato n’abakadde.

Bubonero ki obulaga obulwadde bwa Macrocytosis?

Ebiseera ebisinga, akabonero kokka akalaga obulwadde bwa macrocytosis bwe MCV eyali waggulu ku lipoota ya CBC. Kino kitegeeza kyokka nti obutoffaali bwo obumyufu bunene. Singa obubonero bubaawo, bukwatagana n’ekizibu ekivaako obutoffaali obumyufu okugaziwa.

Okugeza, bwoba olina `Macrocytic Anemia`, oyinza okufuna obubonero nga obunafu , obukoowu, n'olususu olumyufu , nga buno bubonero bwa bulijjo obw'okukendeera kw'omusaayi. Ate era, singa ekivaako kiva ku bbula ly’emmere, oyinza okufuna obubonero ng’ekiddukano , okubulwa okujjukira, n’okubulwa bbalansi .

Ekyo kitegeeza nti olw’okuba waliwo ebintu bingi ebivaako obulwadde bwa macrocytosis, obubonero nabwo busobola okwawukana.

Biki ebivaako obulwadde bwa macrocytosis?

Obutoffaali bw’omusaayi bukolebwa mu busimu bwaffe obw’amagumba. Kale, obuzibu mu kukola obutoffaali obumyufu mu busimu buno n’obuzibu mu nsengeka y’obutoffaali obumyufu bisobola okuleeta Macrocytosis. Oluusi, bw’oba ​​n’obutoffaali obumyufu obutakuze bungi, obuyitibwa `reticulocytes`, mu musaayi gwo, olwo omuwendo gwa `MCV` nagwo guyinza okweyongera. Kino kiri bwe kityo kubanga `reticulocytes` zino nnene mu bunene okusinga obutoffaali obumyufu obukuze.

Ebimu ku bikulu ebivaako obulwadde bwa macrocytosis bye bino:

Ebbula ly’emmere

Ebiriisa nga vitamiini B12 ne folate (vitamin B9) byetaagisa nnyo emibiri gyaffe okukola obutoffaali obumyufu obulungi. Singa ebiriisa bino tobifuna bimala mu mmere gy’olya, oba omubiri gwo bwe guba nga tegusobola kubinyiga olw’obulwadde obumu, obutoffaali bwo obumyufu tebujja kukula bulungi. Obutabeera na vitamiini B12 ne folate kiyinza okuleeta embeera eyitibwa `Macrocytic Anemia`. Okugeza abantu abamu tebalya nva za kijanjalo n’ebibala ebimala. Kino kiyinza okuvaako obutaba na folate. Ate era abantu abatali ba mmere yonna basobola okubulwa vitamiini B12.

Eddagala erimu

Macrocytosis era esobola okuva ku ddagala ery’enjawulo. Ebisinga okumanyibwa ku bino mulimu hydroxyurea, eddagala erijjanjaba obulwadde bwa sickle cell, eddagala ery’enjawulo erijjanjaba kookolo, n’eddagala eriweweeza ku kawuka ka siriimu (ART) erijjanjaba obulwadde bwa siriimu. Bw’oba ​​omira eddagala lyonna ku lino, omusawo wo ajja kuba alimanyi.

Okukozesa omwenge

Okunywa omwenge ekisusse nakyo kisinga okuvaako obulwadde bwa Macrocytosis. Omwenge gukendeeza ku busobozi bw’omubiri okuyingiza ebiriisa naddala ebyetaagisa okukola obutoffaali obumyufu obulungi.

Obulwadde bw’ekibumba

Macrocytosis nayo eyinza okuba akabonero k’obulwadde bw’ekibumba. Obulwadde bw’ekibumba butera, naye si bulijjo, okukwatagana n’okukozesa omwenge. Kyokka n’obulwadde bw’ekibumba busobola okubaawo olw’ensonga endala.

Okukendeera kw’omusaayi mu musaayi

Mu mbeera eyitibwa ``Hemolytic anemia,'' obutoffaali bwo obumyufu bufa nga tebunnatuuka olw'embeera eyaliwo. Kino bwe kibaawo, omubiri gwo gufulumya ``reticulocytes,'' (obutoffaali obumyufu obutakuze) mu musaayi okusobola okumalawo ebbula. Obutoffaali buno obumyufu obutakuze tebusobola kutambuza mukka gwa oxygen ng’obutoffaali obumyufu obukuze.

Okuvaamu omusaayi ekisusse

Singa ofiirwa omusaayi mungi, ka gubeere nga guvudde ku kabenje, okulongoosebwa oba ensonga endala, omubiri gwo gujja kwongera obutoffaali obuyitibwa reticulocytes mu musaayi gwo okusobola okukola ku kufiirwa. Nga bwe kiri mu kukendeera kw’omusaayi (hemolytic anemia), obutoffaali obutakuze buyingira mu musaayi nga tebunnatuuka.

Obulwadde bwa myelodysplastic syndrome

Kino kika kya kookolo akula mu busimu bw’amagumba. Embeera eno eremesa obusigo bw’amagumba okukola obutoffaali obumyufu obulungi.

Obulwadde bwa Hypothyroidism

Macrocytosis era esobola okubaawo mu bantu abalina obulwadde bwa hypothyroidism, endwadde ya thyroid etali nnungi. Kiyinza okubaawo nga olina okukendeeza ku musaayi oba nga tolina musaayi.

Oluusi, tewali nsonga ntegeerekeka esobola kuzuulibwa ku macrocytosis naddala ng’olina macrocytosis yokka nga tolina musaayi.

Omanya otya oba olina obulwadde bwa macrocytosis?

Nga bwe twagambye emabegako, macrocytosis kigambo ekitegeeza obutoffaali obumyufu obugaziwa, so si bulwadde butongole. Singa omuwendo gwa MCV ku lipoota yo eya CBC gusukka 100 fL, kitegeeza nti obutoffaali bwo obumyufu bunene okusinga obwa bulijjo.

Oluusi abasawo basobola okuteebereza ekivaako obulwadde bwa Macrocytosis okusinziira ku buzibu bw’embeera eno. Okugeza, singa MCV eba waggulu nnyo (around 110 – 115 fL), kiyinza okuba akabonero k’okukendeera kw’omusaayi mu macrocytic okusingawo, gamba nga megaloblastic anemia.

Okukebera okuzuula ekivaako obulwadde bwa macrocytosis

Omusawo wo bw’aba yeeraliikirira obutoffaali bwo obumyufu obugaziye, ajja kukubuuza ebibuuzo okumanya ekivaako. Ayinza okubuuza ku byafaayo byo eby’obujjanjabi, eddagala ly’omira, emmere gy’olya, n’okunywa omwenge . Okugatta ku ekyo, ayinza n’okukola ebigezo ebirala:

• Okusiiga omusaayi ogw’okumpi:Kino kizingiramu okukwata sampuli y’omusaayi gwo n’ogutunuulira mu microscope okulaba oba waliwo ebitali bya bulijjo ebiyinza okuba nga bivaako Macrocytosis, gamba ng’obuzibu mu kukula kw’obutoffaali obumyufu.
• Okukebera omuwendo gwa vitamiini B12 ne folate: Singa ebirungo bya vitamiini B12 oba folate mu musaayi biba bitono, kitegeeza nti waliwo ebbula ly’emmere eritafuna biriisa byetaagibwa okukola obulungi obutoffaali obumyufu.
• Reticulocyte count: Okukebera kuno kupima omuwendo gw’obutoffaali obumyufu obutakuze mu musaayi gwo. Kino kiyinza okuyamba okuzuula oba kino kye kivaako MCV yo okubeera waggulu.
• Okukebera enkola y’ekibumba: Kino kikebera engeri ekibumba kyo gye kikola obulungi okusobola okunyiga ebiriisa ebyetaagisa okukola obutoffaali obumyufu obulungi.
• Okukebera obusigo bw’amagumba: Okukebera kuno kuyinza okukolebwa singa omusawo ateebereza nti olina embeera etaataaganya okukola obutoffaali obumyufu. Kino kizingiramu okukwata akatundu akatono ku busimu bwo obw’amagumba n’okebera obutoffaali obwo ng’okozesa microscope okulaba oba waliwo ebitali bya bulijjo.

Obulwadde bwa Macrocytosis bujjanjabwa butya?

Bw’oba ​​tolina bubonero bwa kukendeera mu musaayi, era ng’ebyava mu kukeberebwa kwo tebiraga kintu kirala kyonna ekitali kya bulijjo, oyinza obuteetaaga bujjanjabi bwonna. Bwe kitaba ekyo, obujjanjabi bujja kusinziira ku kivaako obutoffaali obumyufu bwo obungi.

• Singa obulwadde bwo obuyitibwa macrocytosis buva ku bbula ly’emmere, kiyinza okwetaagisa okukyusa mu mmere gy’olya oba okumira eddagala eriweweeza ku vitamiini .
• Singa obuzibu buba ku ddagala ly’omira, omusawo ayinza okukyusa eddagala oba okukuwa eddagala ery’enjawulo .
• Bw’oba ​​olina okukendeeza ku musaayi ogw’amaanyi awamu n’obulwadde bwa macrocytosis, oyinza okwetaaga okuteekebwamu omusaayi .

Ekisinga obukulu kwe kugoberera enteekateeka y’obujjanjabi omusawo gy’akuwa ddala, awatali kulowooza ku kivaako obulwadde bwo obw’amaanyi (macrocytosis).

Macrocytosis esobola okuwona?

Emirundi egisinga, macrocytosis ejja kwedda emabega ng’ekizibu ekikulu kijjanjabiddwa. Buuza omusawo wo engeri obujjanjabi gye bunaakwata ku bulamu bwo.

Oyinza otya okukendeeza ku bulabe bw’obulwadde bwa macrocytosis?

Tuyinza obutasobola kuziyiza buli kimu ekiyinza okuleeta obulwadde bwa macrocytosis. Kyokka, tusobola okukendeeza ku bulabe bwe tulina nga twettanira emize egy’obulamu. Okugeza nga:

• Okwongera emmere erimu vitamiini B12 ne folate – ebyennyanja, ebiva mu mata, amagi , ebibala ebibisi, n’emmere ey’empeke erimu ebirungo ebinywevu – mu mmere yo kiyinza okukendeeza ku bulabe bw’okulwala obulwadde bw’okubulwa omusaayi (macrocytic anemia).
• Kikulu nnyo okussa ekkomo ku kunywa omwenge .
• Ekirala, tobuuka kukeberebwa musaayi buli mwaka. Macrocytosis etera okusangibwa mu butanwa mu kiseera ky’okukeberebwa omusaayi okwa bulijjo. Okuzuula obulwadde buno amangu n’okubujjanjaba kiyinza okuziyiza embeera eno okweyongera.

Kiki ekibaawo singa obulwadde bwa macrocytosis bulekebwa nga tebujjanjabiddwa?

Omusawo yekka y’asobola okuzuula oba Macrocytosis yo kintu kya kweraliikirira. Bw’oba ​​olina obulwadde bwa Macrocytosis wamu n’okubulwa omusaayi, kyetaagisa okunoonya obujjanjabi. Singa tebajjanjabwa, Macrocytic Anemia eyinza okuvaako obuzibu obw’amaanyi mu bulamu.

Kiki kye nsaana okubuuza omusawo?

Bw’okizuula nti obutoffaali bwo obumyufu bunene okusinga ku bwa bulijjo, goberera ebiragiro by’omusawo ku ky’olina okukola. Oyinza okwagala okubuuza ebibuuzo nga:

• Nsaana okweraliikirira MCV yange enkulu?
• Bikebere ki bye nja okwetaaga okuzuula ekivaako obulwadde bwa macrocytosis?
• Nnaaba nneetaaga okujjanjaba ekivaako obutoffaali bwange obumyufu okugaziwa?
• Nkyukakyuka ki mu bulamu bwe nsobola okukola okuddukanya embeera eno eya Macrocytosis?

N’ekisembayo, jjukira (Obubaka bw’Okutwala Awaka) .

Macrocytosis oba MCV enkulu si bulijjo kye kivaako okweraliikirira. Kale totya singa lipoota yo eya CBC eraga emiwendo gino. Funa obulagirizi bw’omusawo wo ku ngeri y’okutaputa ebivuddemu. Okusinziira ku bivuddemu, omusawo ayinza okukuwa amagezi okukyusa mu mmere oba okukozesa ebirungo bya vitamiini. Totya kubuuza engeri obujjanjabi bwo gye bunaakwatamu obutoffaali bw’omusaayi n’obulamu bwo okutwalira awamu. Okusigala nga oli mulamu bulungi kye kintu ekisinga obukulu!