Okubulwa okujjukira kwe kujja n’obulwadde bwa Parkinson? Ka twogere ku bulwadde bwa Parkinson's Disease Dementia!

Ab’omu maka go, oboolyawo maama wo, taata wo, oba omuntu wo ow’oku lusegere alina obulwadde bwa Parkinson? Omuntu ng’oyo abadde yeerabira mpolampola ebintu, okukaluubirirwa okukola ebintu ebyali ebyangu, oba olabye enkyukakyuka mu ngeri gy’alowoozaamu? Mu butuufu, waliwo embeera y’okujjukira n’amagezi eyinza okujja n’obulwadde bwa Parkinson. Leero tugenda kwogera ku mbeera eno eyitibwa `(Parkinson's Disease Dementia)`. Totya, kino ka tukitegeere mu ngeri ennyangu.

Obulwadde bwa Parkinson Obulwadde bw’okubulwa amagezi kye ki?

Mu ngeri ennyangu, obulwadde bwa Parkinson’s Disease Dementia (PDD) kwe kukendeera kw’obusobozi bw’okulowooza n’okukubaganya ebirowoozo ekibaawo mu muntu alina obulwadde bwa Parkinson, waakiri omwaka mulamba oluvannyuma lw’okuzuulibwa obulwadde buno (ebiseera ebisinga buwanvu nnyo).

Abantu abamu batya bwe bawulira ekigambo "Dementia." Naye katutegeere kye kiri. Obulwadde bw’okubulwa amagezi mbeera omuntu gy’akola emirimu gy’obwongo n’efuuka entono okusinga bwe yali, ekizibuwalira okukola emirimu egya bulijjo. Enkola eno ey’obwongo okusobola okukosebwa, waakiri bibiri ku bino wammanga birina okukosebwa:

• Okujjukira
• Okulowooza mu ngeri entegeerekeka
• Olulimi (okwogera, okutegeera) .
• Okukwasaganya ebintu
• Enneeyisa

Ebiseera ebisinga, nga okwerabira kuno okunene tekunnabaawo, embeera eyitibwa ``Mild Cognitive Impairment (MCI)`` esobola okubaawo, emanyiddwa olw'obuzibu obutonotono obw'okujjukira oba okukendeera okutono mu sipiidi y'okulowooza. Kino kitegeeza nti okujjukira kukosebwa katono wadde nga tekuyingirira nnyo mirimu gya buli lunaku. Naye, si misango gyonna egya ``MCI`` nti gigenda mu maaso ne gituuka ku ``Dementia``. Wakati wa 10% ne 20% ku bantu abalina obulwadde bwa Parkinson bayinza okuba ne ``MCI`` yokka mu bulamu bwabwe bwonna.

Nga bw’omanyi, obulwadde bwa Parkinson bulwadde bwa neurodegenerative, oba obulwadde bw’obwongo obunafuya mpolampola obutoffaali bw’obusimu. Okusinga kikosa entambula y’omubiri. Obubonero ng’okukwatagana mu ngalo n’okulwawo okutambula (bradykinesia) bye bisooka okulabika. Kyokka ekiseera bwe kigenda kiyitawo, obulwadde buno era busobola okukwata ebitundu by’obwongo ebifuga endowooza n’ebikolwa. Wano obulwadde bw’okubulwa amagezi we bubaawo.

Embeera eno ya bulijjo etya?

Obulabe bw’okufuna obulwadde bwa Parkinson obw’okubulwa amagezi bwawukana okusinziira ku myaka n’ebbanga ly’omaze ng’olina obulwadde bwa Parkinson. Okugeza nga:

• Abantu abali wakati w’emyaka 60 ne 75 wakati wa 16% ne 20% babadde n’obulwadde bwa Parkinson okumala wakati w’emyaka 5 ne 10.
• Abantu abali wakati w’emyaka 60 ne 75 wakati wa 20% ne 30% babadde n’obulwadde bwa Parkinson okumala emyaka 10 ku 15.
• Embeera eno esobola okubaawo mu bantu 50% ku 60% abasukka mu myaka 75 ababadde n’obulwadde bwa Parkinson okumala emyaka egisukka mu 15.

Bubonero ki obulaga obulwadde bwa Parkinson’s Dementia?

Engeri embeera eno gy’ekwata ku buli muntu eyinza okwawukana, naye waliwo obubonero obumu obutera okulabika:

• Okukaluubirirwa okussa essira: Okukaluubirirwa okusigala ng’ossa essira ku kintu kimu, nga kyangu okuwugulibwa.
• Okubulwa okujjukira: Okukaluubirirwa okujjukira ebintu ebipya, n’oluusi n’okwerabira ebintu eby’edda.
• Ebizibu mu kutegeera amawulire agalabika: Okugeza, okukaluubirirwa okuzuula ekintu kimu mu kifo ekirimu abantu abangi.
• Ne bwe kiba nti omulimu omutono guyinza okuba omuzibu okuteekateeka, okugutandika, n’okugumaliriza.
• Ebizibu by’olulimi: Ebigambo bitabuddwatabuddwa, amannya g’ebintu geerabirwa, era sentensi enzibu zifuuka nzibu okutegeera.
• Okwogera kufuuka okutategeerekeka, ng’okusiwuuka empisa.

Okugatta ku ekyo, enkyukakyuka mu nneeyisa ziyinza okubaawo:

• Enkyukakyuka mu mbeera y‟ebirowoozo: okweyongera ennaku (okwennyamira), okunyiiga ennyo (okunyiiga), n‟okweraliikirira.
• Obutafaayo: Obutayagala kukola kintu kyonna, okuwulira nga buli kimu kikuboola.
• Psychosis: Okulaba ebintu ebitali bya ddala (naddala visual hallucinations), oba okukkiriza ebintu ebitali bya ddala (naddala okulowooza okw’okuwuubaala).

Singa ggwe oba omuntu wo alina obubonero buno, kikulu nnyo okugenda ew’omusawo akuwe amagezi. Osobola okutegeera embeera n’okola ebyetaagisa nga tosattira.

Lwaki obulwadde bw’okubulwa amagezi obwa Parkinson bubaawo?

Ensonga enkulu lwaki kino kibaawo kwe kukuŋŋaanyizibwa kwa puloteyina ezitali za bulijjo eziyitibwa `(Lewy bodies)` mu bwongo. Zino `(Emibiri gya Lewy)` biba bibumbe bitono ebikoleddwa mu puloteyina eyitibwa `(alpha-synuclein)`. Bino bwe bikuŋŋaanyizibwa munda mu butoffaali bw’obusimu `(neurons)` obw’obwongo, obutoffaali obwo bwonoonebwa ne bufa.

Mu bulwadde bwa Parkinson, zino `(Lewy bodies)` zisooka kuteekebwa mu bitundu by'obwongo ebifuga entambula naddala mu kitundu kya `(basal ganglia)`. Eno y’ensonga lwaki obuzibu mu ntambula ng’okukankana n’okutambula mpola busooka kubaawo. Ekiseera bwe kigenda kiyitawo, `(Emibiri gya Lewy)` gino giyinza okusaasaana mu bitundu by'obwongo eby'omutindo ogwa waggulu ebifuga ebintu ng'okulowooza, okujjukira, n'olulimi. Awo we wabeera `(Obulwadde bwa Parkinson Obulwadde bw'okubulwa amagezi)`.

Embeera eno efaananako nnyo n’ekika ekirala eky’okusannyalala ekiyitibwa Lewy body dementia (LBD). Mu butuufu, bannassaayansi abamu balowooza nti endwadde zombi ziva ku kika kye kimu eky’enkyukakyuka mu bwongo ezizingiramu puloteyina alpha-synuclein. Enjawulo esinga eri mu nsengeka obubonero gye bulabika. Ekyo tujja kukyogerako mu kaseera katono.

Ani ali mu bulabe obw’amaanyi obw’okufuna embeera eno?

Ebintu ebikulu ebibiri ebiyinza okuleeta obulwadde bw’okubulwa amagezi obwa Parkinson bye bino:

1. Okwongera ku myaka: Obulabe buno bweyongera n’emyaka.

2. Okweyongera kw’ebbanga ly’obulwadde bwa Parkinson: Obulwadde gye bukoma okumala ebbanga eddene, emikisa gy’okulwala obulwadde bw’okubulwa amagezi gye gikoma okubeera eminene.

Okugatta ku ekyo, okunoonyereza kuzudde nti abantu abalina obubonero obumu obw’obulwadde bwa Parkinson nabo batera okufuna obulwadde bw’okubulwa amagezi. Obubonero obwo mulimu:

• Okubeera n’obubonero obw’amaanyi obw’enkola y’emirimu: Bw’oba ​​olina obubonero obw’amaanyi ng’okukankana n’okukaluubirirwa okutambula.
• Nga bukyali mu kkubo ly’obulwadde bwa Parkinson , obuzibu ku nkola y’obusimu obukola emirimu egy’enjawulo (okugeza, puleesa ekendeera mu ngeri ey’obutiti (orthostatic hypotension), obutakwata musulo) buyinza okubaawo.
• Obuzibu mu ntambula bukosa enjuyi zombi ez’omubiri kyenkanyi (obubonero bw’enkola y’omubiri (symmetrical motor symptoms).
• Eddagala eririmu dopamine eriwonya obulwadde bwa Parkinson terikola bulungi nga bwe kisuubirwa.
• Okubeera n'embeera eyitibwa ``REM sleep behavior disorder'' (mu butuufu mw'ozannya by'oloota).

Kino okitegeera otya ddala?

Ebyembi, tewali kukebera kwonna okuyinza okukakasa amangu ddala nti waliwo obulwadde bwa Parkinson’s Disease Dementia. Omusawo azuula obulwadde buno ng’alowooza ku bintu ebiwerako:

• Babuuza obubonero bwo lwe bwatandika n’engeri gye bukyuse.
• Buuza ku byafaayo byo byonna eby’obujjanjabi.
• Nja kutunuulira ddagala ki ly'omira mu kiseera kino.
• Buuza oba waliwo omuntu yenna mu maka go alina endwadde zino.

Okugatta ku ekyo, okukeberebwa okumu kuyinza okukolebwa okuyamba mu kuzuula obulwadde. Ng’ekyokulabirako, okukebera omusaayi, okukebera ebifaananyi by’obwongo (nga CT scans, MRI scans), n’okukebera obusimu bw’omubiri (neuropsychological tests) ebikebera obukugu mu kulowooza.

Nga bwe nnagambye emabegako, obubonero n’ebivaako obulwadde bwa Parkinson’s Disease Dementia (PDD) ne Lewy Body Dementia (LBD) bifaanagana nnyo. Kale, waliwo enkola entono abasawo gye bakozesa okwawula wakati w’ebintu bino ebibiri:

• Singa obubonero bw’okubulwa amagezi (nga okubulwa okujjukira) bulabika waakiri omwaka gumu (ebiseera ebisinga emyaka egiwerako) oluvannyuma lw’okutandika obuzibu bw’okutambula kw’obulwadde bwa Parkinson (nga okukankana, okutambula mpola), kiyitibwa Parkinson’s Disease Dementia (PDD).
• Singa obubonero bw’okusannyalala bulabika nga tebunnabaawo, mu kiseera, oba mu mwaka gumu bukya buzibu bw’okutambula kwa Parkinson butandika, kiyitibwa `(Lewy body dementia - LBD)`. Abalwadde abamu aba `(LBD)` bayinza obutafuna buzibu bwa Parkinson mu ntambula.

Bujjanjabi ki obukolebwa ku kino?

Ekibuuzo abantu bangi kye babuuza kiri nti oba waliwo eddagala eriwonya kino, oba kiyinza okuwona. Mu butuufu, tewali ddagala lyonna eriyinza okukomya oba okuzzaawo okukula kw’obulwadde bwa Parkinson’s Disease Dementia. Ekyo kintu kya nnaku katono.

Naye toggwaamu ssuubi! Waliwo eddagala n’obujjanjabi ebiyinza okuyamba okufuga oba okukendeeza ku bumu ku bubonero. Okugeza nga:

• `(Ebiziyiza cholinesterase)`:Eddagala eriri mu kiraasi eno, nga donepezil (Aricept®), rivastigmine (Exelon®), ne galantamine (Razadyne®), liyinza okuwa obuweerero obumu okuva ku bubonero obumu naddala okulaba ebirooto, enkyukakyuka mu ndowooza, n’enkyukakyuka mu nneeyisa.
• Selective serotonin reuptake inhibitors (SSRIs) ne serotonin ne norepinephrine reuptake inhibitors (SNRIs): Lino ddagala eritera okuwandiikibwa ku kweraliikirira. Ziyinza okuyamba okufuga enkyukakyuka mu mbeera ng’ennaku, obusungu, n’okutya.
• Obujjanjabi bw‟enneeyisa y‟okutegeera (CBT): Kino kika kya bujjanjabi bwa bwongo, nga buno ngeri ya bujjanjabi bwa kwogera. Kiyinza okuyamba okuddukanya ebintu ng’ebizibu by’enneeyisa n’okunyigirizibwa.

Ttiimu yo ey’abasawo ejja kwogera naawe era esalewo obujjanjabi obusinga okukuyamba. Naye jjukira ekintu kimu. Eddagala erimu liyinza okwonoona obubonero bw’obulwadde bw’okusannyalala. Okugeza, eddagala lya carbidopa-levodopa, eritera okukozesebwa okujjanjaba obuzibu bw’okutambula kw’obulwadde bwa Parkinson, liyinza okwongera okulaba ebirooto n’okutabulwa mu bantu abamu abalina obulwadde bwa Parkinson obw’okubulwa amagezi. Kale, totandika oba tolekera awo kumira ddagala lyonna nga tolina magezi ga musawo.

Wayinza okubaawo okugezesebwa mu malwaliro okugenda mu maaso ku bujjanjabi obupya obw’obulwadde bwa Parkinson’s Disease Dementia. Ekyo nakyo osobola okukibuuza omusawo wo.

Embeera eno egenda etya mu maaso? (Okuteebereza)

Enteebereza y’omuntu alina embeera eno esinziira ku bintu ebiwerako. Wabula okufaananako n’obulwadde bwa Parkinson, Obulwadde bwa Parkinson’s Disease Dementia butera okweyongera okumala ekiseera. Wadde ng’obujjanjabi busobola okuwa obuweerero obumu ku bubonero, emirundi mingi omutindo gw’obulamu guyinza okukendeera.

Kino kiyinza okweyongera mangu ki?

Omutindo Obulwadde bwa Parkinson Obulwadde bw’okusannyalala bwe kweyongera kwawukana nnyo okusinziira ku muntu, nga n’obulwadde bwa Parkinson bwe bugenda bweyongera. Ttiimu yo ey’abasawo esobola okukuwa ggwe n’ab’omu maka go endowooza ku kiki kye musuubira okusinziira ku mbeera yo entongole.

Kino tekiyinza kulemesebwa kubaawo?

Ebyembi, mu kiseera kino tewali kiyinza kukolebwa kuziyiza bulwadde bwa Parkinson’s Disease Dementia okukula. Ate era, tewali ngeri yonna gye tuyinza kukendeeza ku bulabe bw’okubufuna.

Tuyamba tutya omuntu alina obulwadde bw’okubulwa amagezi obwa Parkinson?

Singa omwagalwa wo aba n’embeera eno, ng’oggyeeko okukolagana ne ttiimu y’abasawo okubawa obujjanjabi obusinga obulungi, waliwo ebintu ebirala ebiwerako by’osobola okukola:

• Yiga nga bw’osobola ku bulwadde bwa Parkinson’s Disease Dementia: Gy’okoma okubumanya, gy’okoma okukwanguyira okugumira ebigenda mu maaso. Era, ojja kusobola okulwanirira obulungi omwagalwa wo.
• Yanguyiza embeera ye:Ggyako ebintu ebiteetaagisa mu nnyumba obikuume nga biteredde. Kino kiyinza okukendeeza ku kutabulwa mu birowoozo kwe bafuna. Okubeera n’ettaala entono ekiro kiyinza okuyamba okukendeeza ku ndowooza enkyamu mu kulaba.
• Teekawo enkola eya bulijjo: Okubeera n’enkola eya bulijjo, gamba ng’okulya, okunaaba, n’okwebaka mu kiseera kye kimu buli lunaku, kiyinza okuyamba abantu abalina obulwadde bwa Parkinson’s Disease Dementia okuwulira obulungi era nga balina obukuumi.
• Weegatte ku kibiina ekiwagira: Funa omwagalwa wo naawe kennyini okwenyigira mu bibiina ebiwagira abalwadde ba Parkinson n‟ab‟omu maka gaabwe. Ebibinja bino bisobola okuwa amawulire ag’omuwendo, amagezi, n’okugabana ku by’ayitamu. Gano maanyi mangi nnyo mu lugendo luno.

Obulwadde bw’okusannyalala obwa Parkinson bwawukana ku mbeera endala ez’okubulwa amagezi?

Waliwo ebintu bingi ebivaako obulwadde bw’okusannyalala, era obubonero bwayo bwa njawulo. Obulwadde bwa Alzheimer’s bwe businga okubeera mu kika ky’obulwadde bw’okusannyalala. Okusinziira ku bannassaayansi, obubonero bw’obulwadde bwa Parkinson obw’okubulwa amagezi bwawukana katono ku bwa Alzheimer’s disease dementia. Okugeza nga:

• Abantu abalina obulwadde bwa Parkinson’s Disease Dementia batera okufuna obutafaayo n’okukaluubirirwa okussa ebirowoozo ku kintu okusinga abo abalina obulwadde bwa Alzheimer’s.
• Abantu abalina obulwadde bwa Alzheimer’s dementia bayinza okuba n’obuzibu mu lulimi nga bukyali okusinga abo abalina obulwadde bwa Parkinson’s dementia. Ate era, abantu abalina obulwadde bwa Alzheimer’s bazibuwalirwa okujjukira ebintu ebipya okusinga abo abalina obulwadde bwa Parkinson’s dementia.

Waliwo emitendera egy’enjawulo egy’obulwadde bw’okubulwa amagezi obwa Parkinson?

Abasawo bakkirizza enkola ez’okugabanya obulwadde bwa Parkinson mu mitendera egy’enjawulo. Wabula tewali ngeri ntongole ey’okugabanyaamu obulwadde bwa Parkinson’s Disease Dementia. Kino kiri bwekityo kubanga engeri gye bukosaamu buli muntu n’omutindo gw’eyongera okusajjuka byawukana nnyo. N’olwekyo, kizibu bannassaayansi n’abasawo okugigabanya mu mitendera egy’enjawulo.

N’ekisembayo, ebintu by’olina okujjukira

Si kyangu kukimanya nti olina obulwadde bwa Parkinson, embeera ekosa okujjukira kwo era eyinza okukosa obusobozi bwo okukola emirimu. Kya bulijjo okuwulira ennaku, okunyiiga n’okutya ebiseera eby’omu maaso. Jjukira nti toli wekka mu kiseera kino. Funa obuwagizi bwe weetaaga okuva mu baagalwa bo, ab’omu maka go, mikwano gyo, n’okusingira ddala ttiimu yo ey’abasawo.

Jjukira nti wadde ng’obujjanjabi tebusobola kuwonya mbeera eno mu bujjuvu, busobola okuyamba okufuga obubonero n’okutumbula omutindo gw’obulamu okutuuka ku ddaala eritali limu. Kale, toggwaamu ssuubi era ogende mu maaso n'olugendo luno n'obuwagizi bw'ofuna.

Parkinson 's , obulwadde bw'okubulwa amagezi, okubulwa okujjukira, endwadde z'obwongo, emibiri gya Lewy, endwadde z'obusimu, okulabirira abakadde