Obutoffaali obumyufu mu musaayi gwo bukyusa enkula? Ka twogere ku (Poikilocytosis)!

Oluusi owulira ng’okooye era ng’okooye awatali nsonga? Oba waliwo omusawo eyatunuulidde lipoota yo ey'okukebera omusaayi n'agamba ekintu nga, "Waliwo enkyukakyuka entonotono mu nkula y'obutoffaali bwo obumyufu?" Mu biseera ng’ebyo, ekimu ku bigambo bye tuwulira ye `(Poikilocytosis)` (eyatulwa: poi-ki-lo-say-to-sis). Totya nnyo nga owulira erinnya lino. Kino si bulwadde, naye kiyinza okuba akabonero akalaga nti waliwo ekintu ekirala ekigenda mu maaso munda mu mubiri gwaffe. Kale, kikulu nnyo okubeera nga omanyi kino.

Ddala `(Poikilocytosis)` kye ki?

Mu ngeri ennyangu, ``Poikilocytosis`` kitegeeza nti omuwendo omunene (kwe kugamba, ogusukka mu 10%) ogw'obutoffaali obumyufu mu musaayi gwaffe buli mu nkula ezitali za bulijjo. Kati oyinza okuba ng'olowooza nti, "Kale lwaki enkula y'obutoffaali obumyufu ekwata ku musaayi?"

Lowooza ku butoffaali obulala, ebitundu by’omubiri, n’ekitundu ky’omubiri mu mubiri gwaffe byetaaga amaanyi okusobola okubeerawo n’okukola. Amasoboza ago gaweebwa okisigyeni. Ani amanyi, oxygen ono, ng’okuleeta ssiringi ya ggaasi awaka, atambuzibwa mu mubiri gwonna? Obwo bwe butoffaali bwaffe obumyufu. Mu budde obwabulijjo, bw’omira obutoffaali obumyufu obulungi, bwonna buba bwa sayizi n’enkula y’emu. Ng’ekinusu ekyekulungirivu (nga disiki) ekikonkona katono ku njuyi zombi.

Kale, singa enkula y’obutoffaali buno obumyufu ekyuka (`(Poikilocytosis)`) oba obunene bwe bukyuka (waliwo obulala obuyitibwa `(Anisocytosis)`), tebusobola kutambuza bulungi mukka gwa oxygen. Awo we tufuna embeera nga anemia (obutaba na musaayi mu musaayi). Ekyo kitegeeza nti obutoffaali bw’omubiri tebufuna mukka gwa oxygen gumala ekitegeeza amaanyi.

Enkula ki ezitali za bulijjo ez’obutoffaali obumyufu? (Ebiwuka ebiyitibwa Poikilocytes) .

Abasawo bagabanya obutoffaali buno obumyufu obutali bwa bulijjo (era obuyitibwa `Poikilocytes`) okusinziira ku ndabika yabwo. Bwoba olina `(Poikilocytosis)` mu musaayi, oyinza okulaba ekimu oba ebisingawo ku bino wammanga:

• Acanthocytes / Spur cells : Zino ziringa ettabi ly’amaggwa. Zirina ebiwujjo ebiwanvu, ebigazi, ebiringa enkovu ebifuluma okuva mu luwuzi lw’obutoffaali.
• Codocytes / Target cells : Zino ziringa olubaawo olugendererwamu. Wakati waliwo enzirugavu enzirugavu.
• Dacrocytes / Obutoffaali bw’amaziga : Bulinga amatondo g’amaziga. Oludda olumu olw’akatoffaali lugonvu era nga lusongovu.
• Drepanocytes / Sickle cells : Buno butoffaali bugonvu, obulinga sickle nga busobola okulabibwa mu bantu abalina obulwadde bwa sickle cell.
• Echinocytes : Okufaananako n’enseenene y’omu nnyanja, obutoffaali buno bubikkiddwa emigongo mu mabanga ag’enkanankana wonna.
• Elliptocytes / Ovalocytes oba Cigar cells : Buno buba bwa oval ate nga buwanvu mu ngeri etaali ya bulijjo. Ziyinza okuva ku bunene okuva ku ngeri y’amagi okutuuka ku ngeri ya sigala.
• Schistocytes : Bino bitundutundu bya butoffaali obumyufu. Zitera okuba n’endabika ekikalu, nga zimenyese, naye zisobola okuba ez’engeri yonna.
• Spherocytes: Enkulungo. Ng’omupiira omutono.

Buli kimu ku bika bino kiyinza okukwatagana n’embeera z’obujjanjabi ezenjawulo.

Bubonero ki obulaga embeera eno?

Obubonero bwa ``Poikilocytosis`` bwawukana okusinziira ku kivaako. Kyokka obubonero obutera okulabibwa bwe bumu n’obwo obuva ku kukendeera kw’omusaayi.

Bino bye bimu ku bubonero bw’okukendeera kw’omusaayi:

• Obunafu oba obukoowu obuyitiridde (okuwulira obukoowu bwokka).
• Okukaluubirirwa okussa (dyspnea) – okussa obubi ne bwe wabaawo emirimu emitonotono.
• Omutima okukuba amangu oba mu ngeri etali ya bulijjo (arrhythmia).
• Oluusi owulira eddoboozi lya "whooshing" mu matu go (pulsatile tinnitus).
• Okulumizibwa omutwe .
• Okuziyira .
• Olususu olumyufu .
• Obulumi mu kifuba .

Bw’oba ​​olina ekimu oba ebisingawo ku bubonero buno, kirungi n’ogenda mu basawo amagezi.

Lwaki kino kigenda mu maaso? Ensonga ze ziruwa?

Ebivaako enkula zino ezitali za bulijjo ez’obutoffaali obumyufu bisobola okwawulwamu ebika bibiri ebikulu: ebisikira n’ebifunibwa . Embeera ezimu, gamba nga Myelodysplastic Syndrome, zisobola okuleeta byombi.

Embeera ezisikira

Emirundi egisinga, ebiva ku buzaale biva ku nsobi mu mawulire g’obuzaale (DNA) obutoffaali obumyufu bwe bwetaaga okukula, okukola, n’okuwangaala obulungi. Obutoffaali obumyufu obulina ensengekera ng’ezo ezitali za bulijjo bumenya mangu omubiri nga tegunnakola butoffaali bupya. Kino kiyitibwa hemolytic anemia .

Embeera ezimu ezizaalibwa nga zireeta `(Poikilocytosis)`:

• `(Ensikirano ya Elliptocytosis)`
• `(Obulwadde bwa Spherocytosis obw’ensikirano)`
• `(Obulwadde bwa McLeod Syndrome)`
• `(Obutaba na Pyruvate Kinase)`
• `(Obulwadde bwa Sickle Cell)` (Obulwadde bwa Sickle Cell)
• `(Obulwadde bwa Thalassemia)`

Bino bitera okuba ebintu ebiyisibwa mu milembe.

Obukwakkulizo Obufunibwa

Ekiseera bwe kigenda kiyitawo, embeera z’obujjanjabi ezimu nazo zisobola okuleetera enkula y’obutoffaali obumyufu okukyuka. Okugeza omubiri singa tegufuna biriisa bimala bye gwetaaga okukola obutoffaali obumyufu obulungi, gamba nga vitamiini B12, folate, ne iron, okukendeera kw’omusaayi okw’enjawulo kuyinza okubaawo. Poikilocytosis kabonero akamanyiddwa ennyo ak’ebbula ly’emmere lino. Era kiyinza okuva ku ndwadde, gamba nga kookolo omu, ezitaataaganya okukola obutoffaali obumyufu.

Ezimu ku mbeera ez’oluvannyuma ezireeta `(Poikilocytosis)` ze zino:

• Obulwadde bw’okukendeera kw’omusaayi obuva ku busimu obuziyiza endwadde
• Okwokya (bwe kiba nga kigazi) .
• `(Obulwadde bwa Celiac)`
• Yinfekisoni ez’enjawulo
• Okukendeera kw’omusaayi olw’obutaba na kyuma
• Obulwadde bw’ekibumba
• Leukemia (kookolo w’omusaayi) .
• Obulwadde bw’ekibumba
• Megaloblastic anemia (olw’obutaba na vitamiini B12 oba folate) .
• `(Obulwadde bwa myelofibrosis)`
• Obutwa (e.g. omusulo) .
• Enkola y’okuteekebwamu omusaayi
• Enkola y’okuggyibwako enseke
• Okulumwa omusota

Kino kiyinza okuleeta bizibu ki?

Embeera nnyingi ezireeta poikilocytosis zisobola okuddukanyizibwa n’obujjanjabi, era ezimu zisobola okuwona ddala. Kyokka, embeera ezimu singa tezijjanjabwa, ziyinza okufuuka ez’amaanyi era ne zituuka n’okutta omuntu. Ng’ekyokulabirako, bw’oba ​​olina obulwadde bw’okukendeera kw’omusaayi, oyinza okuwulira ng’okooye nnyo ne kiba nti tosobola kukola mirimu gyo egya bulijjo. Singa ofiirwa obutoffaali obumyufu obulungi obumala okumala ekiseera, kiyinza okuvaako embeera ng’ebitundu by’omubiri okulemererwa .

Naddala mu baana abato, singa wabaawo okukendeeza ku musaayi ogutajjanjabiddwa, kiyinza okukosa enkula yaabwe n’enkula yaabwe.

N’olwekyo, omusawo wo bw’amala okuzuula ekituufu ekikuviirako obulwadde bwa Poikilocytosis, ajja kukuwa obujjanjabi obwetaagisa okutangira ebizibu nga bino.

Kino okizuula otya ddala? (Okuzuula obulwadde)

Ekigezo ekikulu omusawo ky’ayinza okukozesa okuzuula obulwadde bwa poikilocytosis kwe kukebera omusaayi ogw’okumpi (PBS) . Kino kizingiramu omukugu mu laabu okuggya ettondo ly’omusaayi gwo n’agutunuulira mu microscope. Olwo basobola okulaba obutoffaali bwo obumyufu bumeka obulina enkula ey’enjawulo n’enkula ya ngeri ki.

Ebika by’obutoffaali ebimu bisinga kubeera mu mbeera z’obulwadde ezenjawulo. Kyokka ne mu mbeera y’obulwadde y’emu, wayinza okubaawo ebika by’obutoffaali eby’enjawulo. Okugeza, mu mbeera nga `(Hemolytic Anemia)`, `(Megaloblastic Anemia)`, `(Myelofibrosis)`, `(Thalsemia)`, ebika by’obutoffaali ebiwerako ebitali bya bulijjo bisobola okulabibwa.

Abasawo bo bayinza okwetaaga okwongera okukeberebwa okuzuula ekituufu ekikuleetera obulwadde bwa poikilocytosis.

Ebigezo ebirala okuzuula ekivaako `(Poikilocytosis)`

Okubala omusaayi mu bujjuvu (CBC) kutera okukolebwa wamu ne PBS. CBC esobola okukuwa amawulire mangi agakwata ku butoffaali obuli mu musaayi gwo, omuli emiwendo gyabwo n’obunene bwabwo. Ebimu ku bipimo ebiri mu CBC bisobola okuwa ebisingawo ku butoffaali obumyufu, ekiyinza okuyamba okuzuula ekivaako Poikilocytosis. Empisa zino mulimu:

• `Mean Corpuscular Volume (MCV)` : Enkula y'obutoffaali bwo obumyufu obwa wakati.
• `Mean Corpuscular Hemoglobin (MCH)` : Omuwendo gwa hemoglobin ogwa wakati mu butoffaali bwo obumyufu.
• ``Ekigero kya Hemoglobin mu bitundu by'omubiri (MCHC)''.: Omuwendo gwa wakati ogw’obungi bwa hemoglobin mu butoffaali bwo obumyufu.
• `Red Cell Distribution Width (RDW)` : Obutoffaali bwo obw'omusaayi obumyufu bwe bwawukana mu sayizi.

Okugatta ku ekyo, omusawo ayinza okukebera vitamiini B12, folate, ne iron, era ayinza n’okulagira okukeberebwa ekibumba.

Bujjanjabi ki obukolebwa ku kino?

Obujjanjabi businziira ku kivaako poikilocytosis yo n’obubonero bwo bwe buli obw’amaanyi.

Lowooza nti singa ekivaako embeera eno kiba kya bbula lya mmere (e.g. ekyuma, obutaba na vitamiini B12), okumira ebiriisa ebikwatagana, oba okukyusa okudda ku mmere erimu vitamiini B12 oba folate, emirundi mingi kiyinza okugonjoola embeera eno eya `(Poikilocytosis)`.

Embeera nnyingi ezizaalibwa nazo zeetaaga okulondoola n'obwegendereza . Oyinza okwetaaga okuteekebwamu omusaayi buli kiseera okukakasa nti olina obutoffaali obumyufu obumala. Oba oyinza okwetaaga obujjanjabi bwokka okusinziira ku oba olina obubonero.

Embeera eno esobola okuziyizibwa?

Tetusobola kuziyiza bivaako obuzaale obwa ``Poikilocytosis.`` Naye, tusobola okukendeeza ku bulabe bw'ebivaako ebimu ebitandika oluvannyuma.

Emu ku ngeri esinga okulabirira obutoffaali bwo obumyufu kwe kufuna ebiriisa omubiri gwo bye gwetaaga okubukola. Kakasa nti ofuna vitamiini za B ezimala, folate, ne iron . Bino bye birungo ebikulu omubiri gwo bye gwetaaga okukola obutoffaali obumyufu obulungi. Era kiyamba okukendeeza ku mwenge gw'onywa . Omwenge omungi guyinza okukaluubiriza omubiri gwo okunyiga ebiriisa bino.

Biki ebinaabaawo mu biseera eby’omu maaso? (Endowooza)

Okutwaliza awamu, singa ekivaako `(Poikilocytosis)` eba mbeera etandika oluvannyuma, okuteebereza kutera okuba okulungi. Mu mbeera z’obuzaale, okuteebereza kwawukana okusinziira ku mbeera eyaliwo. Okugeza, wadde ng’obulamu bw’abantu abalina `(Sickle Cell Disease)` okutwalira awamu butwalibwa ng’obumpi, obujjanjabi obupya kati busobozesezza okuwangaala emyaka egisukka mu 50 nga bwe bufuga obubonero.

Ddi lw’osaanidde okulaba omusawo?

Bw’oba ​​olina obubonero bw’okukendeeza ku musaayi (ebintu bye twayogeddeko emabegako, ng’obukoowu n’obunafu), mazima ddala olabe omusawo.

Ne bw’oba ​​owulira ng’oli mulamu bulungi era nga tolina bubonero bwonna, kikulu okwekebejjebwa buli mwaka. Omusawo asobola n’okukebera obutoffaali bw’omusaayi. Okukebera omusaayi okwangu, gamba ng’okubala omusaayi mu bujjuvu (CBC), kuyinza okuyamba okuzuula n’okujjanjaba ebizibu by’obulamu nga tebinnaba kufuuka bya maanyi.

Eno ``Poikilocytosis'' mbeera ya maanyi?

`(Poikilocytosis)` yennyini si ya maanyi. Kyokka, ekyoKiyinza okuba akabonero k’embeera y’obujjanjabi erimu ebizibu ebiyinza okuvaako ebizibu singa tebijjanjabwa. N’olwekyo, kikulu okutegeera ddala ekivaako `(Poikilocytosis)` n’okunoonya obujjanjabi bwe kiba kyetaagisa.

Poikilocytosis eyinza okuwulikika ng’embeera ey’amaanyi, naye si bwe kiri. Kye kifaananyi ky’obutoffaali bwo obumyufu abasawo kye bakozesa okwekenneenya obulamu bwo. Bw’okizuula nti obutoffaali bwo obumyufu tebuli bwa bulijjo, tolwawo kubuuza musawo wo ku nsonga eno. Asobola okukubuulira oba kikosa obulamu bwo era bwe kiba bwe kityo, ky’oyinza okukola okumalawo embeera eyo oba okuddukanya embeera gy’olina.

Ebintu ebikulu bye twetaaga okujjukira (Take-Home Message) .

Okay, kale, ensonga enkulu ezirina okujjukira okuva mu bye twogeddeko ze zino:

• Poikilocytosis bwe buba ng’obutoffaali bwo obumyufu obusukka mu 10% buba mu ngeri etaali ya bulijjo.
• Buno si bulwadde, naye buyinza okuba akabonero akalaga nti omuntu alina embeera.
• Obubonero bw’okukendeeza ku musaayi (okukoowa, obunafu, okufuuka omumyufu) era busobola okulabibwa mu mbeera eno.
• Ebivaako biyinza okuba nga byazaalibwa oba nga bifunibwa (obutaba na mmere nnungi, endwadde ezimu).
• Kino kiyinza okuzuulibwa n’okukebera omusaayi okwangu (`PBS`, `CBC`).
• Obujjanjabi businziira ku kivaako, naye emirundi mingi busobola okuddukanyizibwa.
• Okukuuma emmere ennungi kiyinza okuyamba okuziyiza ebimu ku bivaako okutandika oluvannyuma.
• Bw’oba ​​olina obubonero oba ng’olina okubuusabuusa ku nsonga eno, kirungi okugenda ew’omusawo akuwe amagezi.

Kale, nsuubira nti amawulire gano ga mugaso gy’oli. Sigala nga oli mulamu bulungi!

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