Buli kimu ekikwata ku Stem Cell Transplant / Bone Marrow Transplant mu bigambo ebyangu

Omusawo wo bw'akugamba nti weetaaga "okusimbuliza obutoffaali obusibuka" oba "okusimbuliza obusigo bw'amagumba," oyinza okuwulira ng'otya katono, nedda? Ekyo kya bulijjo. Okuwulira ebigambo bino kiyinza okulabika ng’ekintu ekinene, ekizibu, era ekiruma. Naye teweeraliikiriranga. Leero, kino tugenda kukyogerako mu ngeri ennyangu ennyo , ng’okwogera ne mukwano gwo, osobole okuddamu ebibuuzo byonna by’olina mu birowoozo byo.

Okusooka, ka tulabe, obutoffaali buno obusibuka mu mubiri kye ki?

Mu ngeri ennyangu, obutoffaali obusibuka (stem cells) bwe "master cells" mu mibiri gyaffe. Zino ze makolero agasobola okukola kumpi buli katoffaali akalala mu mibiri gyaffe. Okusingira ddala, obutoffaali obusibuka mu magumba gaffe ge makolero amakulu agakola omusaayi gwaffe. Obutoffaali obumyufu, obutoffaali obweru, n’obutoffaali obuyitibwa platelets mu musaayi gwo byonna bikolebwa mu butoffaali buno obusibuka mu musaayi.

Kale, kasita ekkolero lino likola bulungi, tewali kikyamu ku musaayi gwaffe. Naye olw’endwadde ezimu, okugeza, embeera za kookolo nga leukemia, oba endwadde endala ezeekuusa ku musaayi, ekkolero lino liyinza okugenda mu haywire. Ekyo kitegeeza nti etandika okukola obutoffaali obulwadde mu ngeri enkyamu. Oluusi, obujjanjabi bwa kookolo obwa dose ennene nabwo busobola okusaanyaawo obutoffaali buno obulungi.

Waliwo ebika bibiri ebikulu eby’okusimbuliza kuno:

Waliwo enkola bbiri enkulu ez’okusimbuliza obutoffaali obusibuka, okusinziira ku nsibuko y’obutoffaali.

1. Autologous Transplant: Kino kizingiramu okukozesa obutoffaali bwo obuyitibwa stem cells obulamu. Kuba akafaananyi ng’ogenda okuweebwa eddagala eriweweeza ku kookolo erya dose ennene. Obujjanjabi nga tebunnatandika, omusawo ajja kukungaanya obutoffaali obusibuka mu mubiri gwo obulungi n’abutereka bulungi mu firiiza. Olwo, oluvannyuma lw’eddagala eriweweeza ku bulwadde bwa kookolo okutta obutoffaali bwa kookolo, bujja kuzza obutoffaali bwo obulamu obulungi mu mubiri gwo. Kiba ng’okutereka fayiro enkulu nga tonnaba kusengeka kompyuta yo, n’oluvannyuma n’ozizzaawo ng’omaze okugikola.

2. Allogeneic Transplant: Mu kino, olw’okuba waliwo obuzibu ku butoffaali bwo (e.g. leukemia), obutoffaali obusibuka okuva mu muntu omulala omulamu obulungi (omugabi) busimbibwa mu ggwe. Omugabi ono ayinza okuba ow’omu maka (muganda waffe/mwannyinaffe), oba omuntu omulala yenna alina ekika ky’ebitundu ebikwatagana. Ekisinga obukulu wano kwe kukwatagana kw’ebitundu by’omubiri.Okufaananako n’okukwatagana kw’ebibinja by’omusaayi nga ogaba omusaayi, wano ebika by’ebitundu by’omubiri bikwatagana mu ngeri esingako okuba enzibu.

Mu butuufu okusimbuliza kuno kukolebwa kutya? Kiruma?

Kino kibuuzo abantu bangi kye batya. Mu butuufu, okukyusa obutoffaali obusibuka mu mubiri si kulongoosa kwa maanyi. Kilowoozeeko ng’oweebwa eddagala ly’omunnyo. Kino kintu kye kimu.

Obutoffaali buno obusibuka mu mubiri bukuweebwa okuyita mu ttanka ey’enjawulo eyitibwa central venous catheter , eteekebwa mu musuwa omukulu mu kifuba oba mu bulago. Obutoffaali buno buteekebwa mu nsawo ne buyingizibwa mu mubiri gwo, nga bw’oyinza okuteekebwa mu musaayi. Enkola eno esobola okutwala essaawa eziwerako. Mu kiseera kino, ttiimu y’abasawo ejja kukulondoola nnyo.

Tojja kuwulira bulumi bwonna ng’obutoffaali buweereddwa. Wabula oyinza okufuna ebizibu (okusiiyibwa, okuziyira, n’obutabeera bulungi) olw’obujjanjabi obw’eddagala obwaweebwa emabegako. Naye omusawo ajja kukuwa eddagala eryetaagisa okufuga bino byonna.

Obulabe ki n‟ebizibu ebiyinza okuvaamu?

Nga bwe kiri ku bujjanjabi bwonna, waliwo akabi akayinza okuvaamu. Obulabe obusinga obunene kwe kusobola obulwadde buno okuddamu oluvannyuma lw’okusimbibwa. Kyokka, akabi ako kakendeera okumala ekiseera.

Obuzibu obulala obw’enjawulo obuyinza okubaawo naddala mu mbeera y’okusimbuliza obutoffaali obuyitibwa allogeneic transplant (obutoffaali obuggiddwa mu muntu omulala), buyitibwaKiyitibwa Obulwadde bwa Graft-versus-Host Disease (GvHD). Mu ngeri ennyangu, kino obutoffaali bw'abaserikale b'omubiri obukolebwa okuva mu butoffaali bw'omugabi bw'obadde waakasimbuliza mu mubiri gwo bwe butegeera ebitundu by'omubiri gwo nga "eby'ebweru" ne bitandika okubilumba. Kiringa abakuumi abapya abalumba famire yo yennyini. Waliwo obujjanjabi obufuga kino.

Okugatta ku ekyo, waliwo akabi k’okukwatibwa yinfekisoni ez’enjawulo (obuwuka, akawuka, ffene) ng’abaserikale b’omubiri banafuwa.

Kitwala bbanga ki okuwona?

Kino kijja kwawukana okusinziira ku kika ky’okusimbibwa kw’obadde okyusizza.

• Omuntu eyasimbuliza autologous transplant (obutoffaali bwo) ebiseera ebisinga asobola okuwona mu myezi nga ebiri.
• Kiyinza okutwala emyezi egiwerako okutuuka ku mwaka omuntu eyasimbulizibwa mu ngeri ya allogeneic (obutoffaali obugaba) okuwona mu bujjuvu.

Ekiseera kino eky’okuwona kye kiseera obutoffaali obusibuka obupya obuyingiziddwa we bugenda mu busimu bw’amagumba, ne busenga awo (engraftment), ne butandika okukola obutoffaali obupya obw’omusaayi obulamu. Ennaku 100 ezisooka oluvannyuma lw’okusimbuliza omuntu mu ngeri ya allogeneic zikulu nnyo naddala. Abasawo bayinza okukuwa amagezi okubeera okumpi n’eddwaaliro mu kiseera kino.

Ebintu by’osobola okwekolera ng’owona

Luno lugendo luwanvu, kale kikulu nnyo okwerabirira obulungi mu kiseera kino.

• Olususu lwo lukwate ng’olw’omwana: Olususu lwo luyinza okuba nga lunyirira nnyo ng’omaze okujjanjabwa. Kozesa ssabbuuni omugonvu ne ssabbuuni. Kuuma olususu lwo nga lunnyogovu era weekuume ng’ogenda mu musana.
• Lya emmere erimu ebiriisa: Kino kikulu nnyo. Lya ennyama, ebyennyanja, enva endiirwa, ebibala n’empeke ezifumbiddwa obulungi. Mu kiseera kino weewale okulya saladi embisi, ebibala ebitannaaba, amagi amabisi, n’amata agatali galongooseddwa kubanga bitera okuleeta yinfekisoni.
• Weekuume obutakwatibwa yinfekisoni: Naaba nnyo mu ngalo. Weewale ebifo ebirimu abantu abangi n’ebifo abantu we balwadde. Buuza omusawo wo kugema ki kw’osaanidde okufuna.
• Labirira amannyo go: Genda ew’omusawo w’amannyo buli luvannyuma lwa myezi 6. Kuuma obuyonjo obulungi mu kamwa.
• Funa ekiwummulo ekinene: Ennaku ezimu ojja kuwulira ng’okooye nnyo. Ennaku endala ojja kuwulira bulungi. Tofaayo kubeera na lunaku olukooye, kabonero kokka akalaga nti omubiri gwo gwetaaga okuwummula.
• Lowooza ku bulamu bwo obw’omutwe: Kya bulijjo okuwulira ng’olina ebizibu mu nneewulira mu kiseera kino. Bw’oba ​​owulira ng’olina ekiwuubaalo, yogerako n’omusawo wo, ab’omu maka go, era funa obuyambi okuva eri omubuulirizi bwe kiba kyetaagisa.

Bw’oba ​​olina obubonero buno, kuba essimu y’omusawo mu bwangu.

Bw’ofuna obubonero bwonna ku buno wammanga ng’owona, tegeeza ttiimu y’abasawo mu bwangu.

Ku muntu okulwanyisa kookolo oba obuzibu mu musaayi, okusimbuliza obutoffaali obusibuka mu mubiri kiyinza okukyusa obulamu bwe. Naye si lugendo lwangu. Kyetaaga amaanyi mangi mu mubiri ne mu birowoozo. Bw’oba ​​olowooza ku bujjanjabi buno, yogerako mu lwatu n’omusawo wo era otegeere ebirungi n’ebibi. Bajja kukuwa amagezi agasinga obulungi okusinziira ku mbeera gy’olimu.