Omanyi ku bulwadde bwa Takayasu obwa Arteritis? Ka twogere ku nsonga eno!

Wali owuliddeko ku bulwadde obuyitibwa Takayasu's Arteritis? Erinnya lino liyinza okuwulikika ng’ekyewuunyisa katono, nedda? Naye embeera etali ya bulijjo eyinza okukosa emisuwa gyaffe naddala emisuwa eminene egitandikira mu mutima n’amatabi agaguvaamu. Era oluusi kiyitibwa ‘obulwadde obutaliimu pulse.’ Leero, tugenda kukyogerako mu bujjuvu, mu ngeri ennyangu ennyo, naawe osobole okukitegeera obulungi.

Ddala Arteritis ya Takayasu kye ki?

Mu ngeri ennyangu, obulwadde bw’emisuwa gya Takayasu buzimba emisuwa gyaffe, ekitegeeza okuzimba oba okuzimba (vasculitis). Naddala bukosa emisuwa egisinga obunene mu mubiri gwaffe. Lowooza ku kino, omusuwa omukulu ogutwala omusaayi ogulimu omukka gwa oxygen okuva ku mutima gwaffe okutuuka mu mubiri gwonna, gwe tuyita ‘great aorta’ oba ‘aorta’. Obulwadde buno businga kukwata musuwa gwa aorta, n’emisuwa emirala eminene egitabikira ku gwo ne gitwala omusaayi mu mikono gyaffe, mu bulago n’obwongo bwaffe. Omanyi ekibaawo ng’okuzimba kuno kubaddewo? Ebisenge by’emisuwa gyaffe byonoonese. Olwo ebitundu ebimu eby’emisuwa egyo ne binafuwa ne bisobola okubumbulukuka ng’akapiira. Kino tukiyita ‘aneurysm’. Ate era emisuwa giyinza okuzimba ne gifunda. Olwo okutambula kw’omusaayi ne kuziyizibwa. Oluusi omusuwa guyinza okuzibikira ddala, oguyitibwa ‘occlusion’. Tekitera kubaawo, embeera eno esobola n’okukosa emisuwa egigaba omusaayi mu mutima, ebyenda, ensigo n’amagulu.

Ani asinga okukosebwa embeera eno?

Obulwadde bwa Takayasu’s Arteritis (TAK) bulwadde obusinga okukwata abavubuka. Businga kubeera mu bakyala abali wakati w’emyaka 20 ne 40. Abalwadde batera okuba wakati w’emyaka 15 ne 35 nga bazuuliddwa. Ebitundu nga 80% ku 90% ku abo abalina obulwadde buno bakyala. Abasawo embeera eno bagilaba nnyo mu nsi nga Japan n’abantu abava mu Mexico, Buyindi, ne East Asia. Ne mu mawanga nga Amerika, buli mwaka abantu babiri ku basatu bokka abapya abakwatibwa obulwadde buno ku buli bukadde. Kino kitegeeza nti embeera etatera kubaawo.

Obulwadde bw’emisuwa bwa Takayasu bukosa butya omubiri gwange?

Emisuwa bwe gifunda, omuwendo gw’omusaayi ogutuuka mu bitundu by’omubiri n’ebitundu ebiweebwa emisuwa egyo gukendeera. Kilowoozeeko ng’omudumu gw’amazzi oguzibiddwa, ekikendeeza ku bungi bw’amazzi agakulukuta. Naye mu bulwadde bw’emisuwa gya Takayasu (TAK), enkyukakyuka zino zitera okubaawo mpola mpola. Kale emibiri gyaffe girina obudde okumanyiira okutambuza omusaayi nga giyita mu makubo amalala. Amakubo gano ag’enjawulo galinga amakubo amatono ge tukozesa ng’oluguudo olukulu luzibiddwa. Naye bypass zino ziyinza obutasobola kutwala musaayi mungi bulijjo ng’omusuwa omunene ogwasooka. Mu budde obwabulijjo, omuwendo gw’omusaayi ogukulukuta nga guyita ku kizibiti gumala okugabira ebitundu by’omubiri omukka ogusinga obutono n’omusaayi gwe byetaaga okusobola okuwangaala. Naye si bulijjo nnyo, singa emisuwa gino egy’okukyusakyusa tegikola bulungi, ebitundu by’omubiri bisobola okufa kubanga tebirina mukka gwa oxygen n’omusaayi.

Bubonero ki obulaga obulwadde buno?

Abantu abamu abalina obulwadde bwa Takayasu arteritis (TAK) bayinza obutaba na bubonero bwonna. Kyokka, nga kitundu ku balwadde bayinza okufuna obuzibu mu bulambalamba n’obunafu. Obubonero obusooka (omutendera 1): Buno bwe bubonero obulabika ku ntandikwa y’obulwadde:

• Okubeera n’omusujja.
• Okuwulira nga okooye nnyo ( Fatigue ).
• Obulumi mu binywa n'ennyondo .
• Emmere tewooma .

Obubonero obw’omutendera ogw’oluvannyuma (omutendera 2): Obulwadde bwe bugenda bweyongera, obubonero nga buno buyinza okulabika:

• Obulumi mu kifuba .
• Okukaluubirirwa okussa .
• Okulumizibwa omutwe .
• Okuwulira ng’aziyira.

Obubonero obuva ku kufunda kw’emisuwa n’okukendeeza ku musaayi:

• Okukoowa, okulumwa oba okuzimba emikono n’amagulu.
• Obulumi mu lubuto olw’omusaayi okukendeera mu byenda.
• Puleesa olw’omusaayi okukendeera mu nsigo.
• Stroke (kino tekitera kubaawo nnyo).
• Omutima okulwala (kino nakyo tekitera kubaawo).

Kiki ekyavaako Takayasu okulwala emisuwa?

Mu butuufu tewali amanyi kituufu ekivaako obulwadde bw’emisuwa gya Takayasu (TAK).. Wabula abasawo n’abanoonyereza balowooza nti eyinza okuba ‘embeera y’abaserikale b’omubiri’. Kwe kugamba, abaserikale b’omubiri gwaffe abalwanyisa endwadde, mu bukyamu balumba ebitundu byakyo ebiramu. Kiringa eby'okwekuuma byaffe bye bitukolako obulabe. Abanoonyereza abamu balowooza nti emisuwa egimu egya Takayasu giyinza okuba nga giva ku buzaale obusikira abazadde bombi. Abazadde abo bayinza obutaba na bubonero, kubanga balina kkopi emu yokka ey’obuzaale. Naye singa osikira obuzaale obwo obw’enjawulo okuva mu bazadde bombi, osobola okufuna embeera eyo n’obubonero bwayo.

Obulwadde buno buzuulibwa butya?

Omusawo wo ajja kuzuula obulwadde bw’emisuwa gya Takayasu ng’atunuulira ensonga eziwerako awamu, so si emu yokka.

• Ebyafaayo by’obujjanjabi ebijjuvu n’okukeberebwa omubiri: Kino kikolebwa okugoba embeera endala ezirina obubonero obufaananako n’obwo. Omusawo bw’akozesa ekyuma ekiwuliriza okukebera emisuwa gyo, bayinza okuwulira eddoboozi eritali lya bulijjo eriyitibwa ‘bruit’ munda mu misuwa. Emisuwa bwe giba mifunda nnyo, kizibu omusaayi okugiyitamu, nga mu kiseera ekyo eddoboozi we liwulirwa.
• X-rays: Zino ziraga omusuwa gwo we gwonoonese n’obuzibu bw’okwonooneka.
• Okukebera okuzuula okufunda kw’emisuwa oba emisuwa: Waliwo enkola ez’enjawulo ez’okukebera kino.

Biki ebikebera okuzuula obulwadde?

Waliwo okukebera okuwerako okuyinza okuyamba omusawo okukakasa nti obulwadde buno:

• Magnetic Resonance Imaging (MRI): Kino kigezo ekitakozesa X-ray. Ebifaananyi bitondebwa nga tukozesa magineeti ennene, amayengo g’amasoboza ag’amasannyalaze, ne kompyuta.
• Computed Tomography (CT) scan: X-ray ne kompyuta zikola ebifaananyi by’ebitundu by’omubiri eby’omunda, omuli n’emisuwa eminene.
• Angiography: Kino kizingiramu okukuba ebifaananyi bya X-ray eby’omunda mu misuwa gyo. Omusawo ayingiza ekyuma ekigonvu ekiwanvu ekiyitibwa catheter mu musuwa omunene mu kisambi oba mu mukono gwo n’agulungamya okutuuka ku musuwa ogwetaaga okwekebejjebwa. Oluvannyuma, langi ey’enjawulo (contrast material) efuyibwa okuyita mu catheter mu misuwa. Bwe bakubwa X-ray, langi eyo efuula emisuwa okulabika obulungi mu bifaananyi. Oluusi, MRI era esobola okukozesebwa okukola angiography.
• Positron Emission Tomography (PET scan): Mu kukebera kuno, omusawo wo akukuba ekirungo ekikuba amasannyalaze ng’ayita mu mpiso mu musuwa oguli mu mukono gwo. Ekintu kino bwe kitambula mu mubiri gwo, sikaani ekizuula n’ekola ebifaananyi.
• Ultrasound: Kino kiyamba okukola ebifaananyi by’emisuwa nga tukozesa amaloboozi.

Obulwadde bw’emisuwa bwa Takayasu bujjanjabwa butya?

Eddagala lisobola okufuga okuzimba, oba okuzimba. Kyokka abantu abamu bayinza okwetaaga okulongoosebwa okusobola okuyita ku musuwa oguzibiddwa ne bakola ekkubo eppya omusaayi mwe guyita. Corticosteroids: Corticosteroids, nga prednisone (e.g., Rayos®, Sterapred®) oba prednisolone (e.g., Flo-Pred®, Orapred®), ze zisinga okujjanjaba obulwadde bw’emisuwa gya Takayasu (TAK).

Eddagala lino likola ebyewuunyo mu kumalawo okuzimba okukola mu misuwa n’okuteeka obulwadde mu kusonyiyibwa.

Omusawo wo ajja kukendeeza mpolampola ddoozi ya prednisone okutuuka ku ddoozi esinga obutono ekola okukendeeza ku buzibu obuvaamu. Abantu abamu basobola okulekera awo okumira eddagala lino mpolampola nga tebalina bubonero buzzeemu. Wabula eddagala lino erya corticosteroids terikola ddala ku bantu abamu. Ate era, abantu abasukka mu kitundu abamira eddagala lino bayinza okuddamu okulaba oba embeera yaabwe yeeyongera okwonooneka. Eddagala eriziyiza abaserikale b’omubiri: Abasawo era batera okuwandiika eddagala eriziyiza abaserikale b’omubiri, gamba nga:

• Eddagala lya Methotrexate (okugeza Rheumatrex®, Trexall®) .
• Azathioprine (okugeza Imuran®, Azasan®) 100 .
• Ekirungo kya Mycophenolate (okugeza Cellcept®, Myfortic®) .
• Ekirungo kya Leflunomide
• Ekirungo kya Cyclophosphamide

Eddagala lino eriziyiza obusimu bw’omubiri bwe likozesebwa ne prednisone, abantu nga 50% abaali bafunye obulwadde bwa flares basobola okuwona obubonero bwabwe era basobola okulekera awo mpolampola okumira prednisone. Tumor-Necrosis Factor (TNF) inhibitors: Abantu abamu bayinza n’okuweebwa eddagala eriyitibwa TNF inhibitors okuyamba okulwanyisa okuzimba. Eby’okulabirako ku bino mulimu:

• Etanercept, eddagala eriweweeza ku bulwadde
• Infliximab eddagala eriweweeza ku bulwadde
• Eddagala lya Tocilizumab

Okutwaliza awamu, abantu nga 25% abalina obulwadde bw’emisuwa gya Takayasu tebasobola kufuga bulwadde buno mu bujjuvu nga tebagenda mu maaso na ddagala.

Biki ebiva mu bujjanjabi buno?

Eddagala erikozesebwa okujjanjaba obulwadde bw’emisuwa gya Takayasu liyinza okuba n’ebizibu eby’amaanyi. Kyokka eddagala eddala liyinza okuyamba okufuga ebizibu bino. Ebizibu ebivaamu biyinza okuli:

• Okukendeera kw’obuziyiza eri yinfekisoni.
• Okukendeera kw’amagumba (osteoporosis).
• Obuzibu okulaba.
• Okukonziba.

Eddagala lya corticosteroids litandika okukola mu ssaawa ntono ng’otandise obujjanjabi, n’olwekyo oyinza okuwulira obuweerero amangu.

Bujjanjabi ki obulala obukozesebwa?

Mu mbeera ezimu, puleesa (hypertension) eyinza okuva ku kufunda kw’emisuwa okutuuka mu nsigo. Mu mbeera eno, omusawo asobola okukozesa ekintu nga bbaatule okugaziya omusuwa ogufunda, oguyitibwa angioplasty. Oba, okulongoosa omusaayi (bypass operation) kuyinza okukolebwa okusobozesa omusaayi okutambula mu ngeri eya bulijjo okutuuka mu nsigo. Kino kiyinza okuyamba okuzza puleesa mu mbeera eya bulijjo nga tomira ddagala lya puleesa. Abantu abamu bayinza okuba n’obuzibu obw’amaanyi ng’emisuwa gifunda mu mikono oba mu magulu, ekizibuwalira okutambula oba okukola emirimu emirala. Okulongoosa okuyita mu bypass nakyo kisobola okutereeza ebizibu bino. Singa wabaawo okuzimba emisuwa, osobola okuddaabirizibwa ng’olongooseddwa oba okuyita mu bypass. Abantu abamu abalina obulwadde bw’emisuwa gya Takayasu nabo bayinza okwetaaga okukyusa ekyuma ekiyitibwa aortic valve.

Nze nneerabirira ntya?

Abantu bangi abalina obulwadde bw’emisuwa gya Takayasu nabo balina puleesa (hypertension). Kikulu okufuga kino. Bw’otojjanjaba puleesa, ebintu nga bino bisobola okubaawo:

• Storoko.
• Obulwadde bw’omutima.
• Okulemererwa kw’ekibumba.

Bw’oba ​​omira eddagala eriziyiza abaserikale b’omubiri, lowooza ku ky’okugema eddagala lino okukuuma yinfekisoni:

• Eddagala erigema ssennyiga.
• Eddagala erigema ekifuba.
• Eddagala eriweweeza ku bulwadde bwa Herpes zoster (Shingles).

Omuntu alina obulwadde bw’emisuwa gya Takayasu ayinza kusuubira ki?

Wadde nga tewali ddagala liwonya bulwadde bwa Takayasu, bulwadde buno bujjanjabibwa. Abantu abasinga abalina obulwadde buno bawona nga bajjanjabwa. Wabula abantu bangi basobola okulema okutuuka ku ddaala eritali limu, oba nga tebatera kufuuka balema ddala, olw’obulwadde buno. Ebiva mu bulwadde buno bisobola okukosa ennyo emirimu gya buli lunaku. Abantu nga kitundu ku bantu abalina obulwadde bw’emisuwa gya Takayasu balina okukola enkyukakyuka mu mirimu gyabwe. Wabula abantu nga 25% abalina obulwadde buno babeera mu bulamu obwa bulijjo ddala. Abalala 25% babadde balina okukola enkyukakyuka ezimu mu mirimu gyabwe. Abantu abalina obulwadde buno obutawona balina okwekebejjebwa buli kiseera era bwe kiba kyetaagisa okukyusa mu ddagala lyabwe. Abasawo era balina okulondoola ebizibu ebiva mu ddagala lino n’okukebera omusaayi. Bino wammanga biyinza okuba ebizibu ebiva ku bulwadde bw’emisuwa gya Takayasu:

• Omutima okulemererwa.
• Storoko.
• Okuzimba omusaayi.
• Obulwadde bw’omutima.

Takayasu arteritis bulwadde obumala ebbanga eddene nga bukula mpola. Ojja kwetaaga obujjanjabi obw’ekiseera ekiwanvu, emirundi mingi ng’okozesa eddagala. Mu nsi nga Amerika ne Japan, abantu nga 3% abalina obulwadde bw’emisuwa gya Takayasu bafa mu myaka etaano egy’ekigero egy’obulwadde buno. Kino kiyinza okuba nga kiva ku kuba nti abasawo basobola okuzuula obulwadde buno nga bukyali ne babujjanjaba obulungi. Mu bitundu by’ensi ebirala, ebivaamu biyinza okuba ebibi ennyo olw’okulwawo okuzuula obulwadde n’okujjanjaba oba obutafuna bujjanjabi bubi. Singa tebujjanjabwa, obulwadde bw’emisuwa gya Takayasu buyinza okutta omuntu.

Nlabirira ntya obulamu bwange?

Kikulu okulondoola engeri gy’owuliramu n’okusigala ng’okwatagana n’omusawo wo buli kiseera osobole okukwata obubonero bwonna obupya oba obweyongera okwonooneka nga bukyali.

Ddi lwe nnina okulaba omusawo?

Singa obubonero bwo obw’emisuwa gya Takayasu bukomawo ng’ofunye obujjanjabi oba ng’omaze okujjanjabibwa, laba omusawo amangu ago. Bw’oba ​​oteekateeka okufuna olubuto, yogerako n’omusawo wo. Kisoboka okufuna olubuto olulungi ng’olina obulwadde bw’emisuwa gya Takayasu, naye kikulu okumanya engeri y’okubuddukanyaamu.

Ddi lwe nnina okugenda mu kitongole ekijjanjaba abalwadde ab’amangu (ETU) ?

Bw’oba ​​olina obubonero buno bwonna, kuba 911 mu bwangu (mu Sri Lanka, kuba ku 1990 Suwaseriya Ambulance Service oba genda mu ddwaaliro erikuli okumpi):

• Obulumi mu kifuba.
• Okukaluubirirwa okussa.
• Puleesa enafu.
• Obubonero bw’okulwala omutima (e.g., okulumwa ennyo mu kifuba okubunye wansi ku mukono, okutuuyana, okuziyira).
• Obubonero bw’okusannyalala (e.g., okugwa ku ludda olumu olwa ffeesi, okuzirika mu mukono, okukaluubirirwa okwogera).

Bibuuzo ki bye nnina okubuuza omusawo wange?

• Nja kumala bbanga ki okumira eddagala eriweweeza ku bulwadde bw’emisuwa gya Takayasu?
• Mirundi emeka gye nneetaaga okujja okukola enteekateeka z’okugoberera?
• Embeera yange esobola okufugibwa awatali kulongoosebwa?
• Mirundi emeka gye nneetaaga okukeberebwa ebifaananyi?

N’ekisembayo, by’olina okujjukira (Obubaka bw’okutwala awaka) .

Olw’okuba obulwadde bwa Takayasu’s Arteritis bulwadde bwa bbanga ddene, oba ‘obutawona’, ojja kwetaaga okulaba omusawo buli kiseera. Ekiseera bwe kigenda kiyitawo, obubonero bwo buyinza okuva ku butafugibwa ne bufuuka obufugibwa. Eno y’ensonga lwaki kikulu okubeera ng’okwatagana n’omusawo buli kiseera. Totya kubuulira musawo wo singa olaba enkyukakyuka yonna mu bulamu bwo. Omusawo wo ajja kwagala okukimanya, kubanga awo w’asobola okukuyamba.

Jjukira nti ne bw’oba ​​n’obulwadde buno, bw’ofuna obujjanjabi obutuufu era ng’ogoberera amagezi g’abasawo, naawe osobola okubeera n’obulamu obulungi. Sigala nga oli mugumu!

Takayasu’s arteritis, Takayasu’s arteritis, obulwadde obutasalako, obulwadde bw’emisuwa, aorta, emisuwa, obulwadde bw’emisuwa, puleesa, obulwadde bw’abaserikale b’omubiri