I taksa invenna a chak lo em ni? Agranulocytosis chungchang hi i zir dawn nia.

Khawsik leh flu i vei fo thin a, natna nasa tak i nei thin em? A châng chuan, natna tenau tak pawh hi a nasat phah thei a, a dam leh theih nân hun rei tak a daih thei bawk? A chhan ber chu i taksa invenna chak lohna a ni thei a, chu chu natna laka min vengtu sipai chak lohna a ni thei. Vawiin hian hetiang huna rinhlelh theih, tlem a hlauhawm thei, mahse enkawl theih tur dinhmun kan sawi dawn a ni.

A awlsam zawngin Agranulocytosis chu eng nge ni?

Agranulocytosis (a lam tur: "a-gra-nu-lo-cy-to-sis") hi nunna atana hlauhawm tak a ni a , kan thisena thisen var chi khat neutrophils awm zat chu nasa takin a tlahniam a ni.

Kan taksa hi ram ang maiin han ngaihtuah teh. Tichuan thisen var (white blood cells) chu chu ram venghimtu sipai an ni. He sipaiah hian battalion hrang hrang a awm a. Chumi zingah chuan neutrophils te hi commando group bik an ni a , an hmuh veleh hrik bei turin an kal thin . Chuvangin heng commando te hi an tlem hle a nih chuan pawn lam atanga hrik te tak te pawhin awlsam takin kan taksa a rawn bei a, min ti na thei a ni.

Hetiang dinhmun hian natna khirh tak tak, min tichhe lo tlangpui natna hrik atang pawhin natna khirh tak tak lak theihna a siam thei che a ni.

Chuti a nih chuan Neutropenia leh Agranulocytosis hi eng nge an danglamna?

Neutropenia tih thumal pawh i hre tawh mai thei. Heng pahnih hi ri inang mahse, a danglamna tlem a awm.

• Neutropenia: Neutrophils awm zat pangngai aia tlem zawkna dinhmun eng pawh.
• Agranulocytosis: Hei hi neutropenia natna khirh ber leh hlauhawm ber a ni.

A awlsam zawngin neutrophil level a tlahniam lutuk chuan Agranulocytosis kan ti thin.

Hetiang dinhmun hi eng chhan nge ni?

Agranulocytosis hi kawng lian pahnih a awm thei.

1. Inherited Agranulocytosis: Hei hi neutrophils siamtu genes a chhiat vang a ni. Hei hi a tlem hle a, nausen naupang leh naupangte zingah a tam ber.

2. Acquired Agranulocytosis: Hei hi a tam ber a ni. Hei hi chhan hrang hrang a awm thei. Mahse 70% vel ah chuan damdawi thenkhat kan ei thin side effect a ni. Hetiang chi hi puitling zingah a tam zawk.

A hnu lama agranulocytosis lo awm chhan berte

• Damdawi thenkhat: He natna hi damdawi chi hrang hrang, antibiotics thenkhat, rilru lam natna damdawi (e.g. clozapine), leh thyroid natna damdawi (e.g. methimazole) te avanga lo awm thei a ni.
• Chemotherapy: Cancer cells te a chhiat chuan neutrophils, cell hrisel tak tak, rang taka inthen darh thin te pawh a chhe thei bawk.
• Autoimmune diseases: Hei hi kan taksa ngeiin immune system a tihsual a, mahni cell hrisel tak takte a beih hian a ni. Entirnan, Lupus leh Rheumatoid Arthritis ang chi natna te hi a ni.
• Bone Marrow Diseases: Bone marrow hi kan thisen cell zawng zawng siamtu factory a ni. Chuvangin, he factory tibuaitu natna, cancer ang chi leukemia emaw aplastic anemia emaw te hian neutrophil siamchhuahna a tichhe thei a ni.
• Infection thenkhat: He natna hi natna khirh tak tak, Malaria leh TB vang pawh a ni thei.
• Nutritional deficiencies: He risk hi hun rei tak chhunga vitamin B12 leh folate ang chi nutrients tlakchhamnaah pawh a awm bawk.
• Chemical tha lo: Lead emaw mercury emaw ang chi chemical tha lo ei hian.

Agranulocytosis natna lan chhuah dan chu engte nge ni?

Neutrophil count a tlem avangin he natna lan chhuahna bulpui ber chu infection a ni . Chungte chu a lo lang nghal thei a, a lo thang zauh zauh thei bawk.

Hmuh theih thil langsar ber berte chu hengte hi an ni:

• Khawsik nasa tak, khur, leh khawsik nei .
• Heart rate leh thawk chakna a sang.
• Tun hmaa awm ngai lo taksaah hahna leh chak lohna hriatna .
• Thlarau na, hmui hring leh thisen chhuak.
• Kawng leh kawr natna avanga ei harsa .
• Thisen sang (hypotension) tlahniam nghal vat chuan muhil leh luak chhuak ang maiin a awm thin.

Engtin nge doctor hian he natna hi a hriat theih ang?

A chunga tarlan symptoms te hi i neih chuan, a bik takin infection i neih fo chuan doctor in a enfiah ang che. Hetiang natna i neih leh neih loh hriat nan test pawimawh ber chu thisen chhiar kimchang (CBC) a ni. A chang chuan hei hi full blood count (FBC) kan ti bawk.

He test hian i thisena neutrophils awm zat dik tak a teh thin. Microliter khatah neutrophil count 100 aia tlem a nih chuan Agranulocytosis a ni tih hmuhchhuah a ni.

Chu bâkah, doctor chuan a chhan hriat nân test dang neih belh tûrin thu a pe thei bawk.

• Bone Marrow Biopsy: He test hi thisen cell siamna factory bone marrow-ah harsatna a awm em tih hriat nan tih a ni.
• Genetic Testing: Hei hi pianpui natna a nih rinhlelhna a awm chuan he test atan hian refer theih i ni.

Agranulocytosis hi eng enkawlna nge ni?

Hei hi dinhmun hlauhawm tak ni mah se, chanchin lawmawm tak chu a enkawlna tha tak tak a awm tih hi a ni. Enkawlna chu a natna thlentuah a innghat a ni.

• Causative Medication tihtawp: Hetiang natna thlentu hi i damdawi ei a nih chuan, i tih hmasak ber leh pawimawh ber chu chu damdawi ei kha bansan hi a ni. Mahse, nangmah chauhin i damdawi ei kha bansan ngai suh. I doctor nen inbiakna neihpui la, him taka tih theih turin a thupek zawm ngei ang che.

• Antibiotics: I taksaah natna hrik i neih tawh chuan i doctor chuan a do turin antibiotics chak tak a pe ang.

• G-CSF injection: Hengte hi Granulocyte Colony-Stimulating Factor (G-CSF) an ti a. Heng injection te hian ruhro a tichak a, neutrophil cells siam rang zawk turin a pui bawk.

• Immunosuppressants: A chhan chu autoimmune disease a nih chuan, overactive immune system tihreh nan prednisone ang chi damdawi pek theih a ni.

• Bone Marrow Transplant: Enkawlna dang a hlawhtlin loh chuan mi hrisel atanga ruhro thlak hi a tawp ber atan tih theih a ni.

Engtin nge enkawl lai hian hri kai lakah ka inven theih ang?

Hetiang natna vei enkawl lai hian natna hrik kai loh a pawimawh hle.

• I kut chu sahbawn hmangin uluk takin silfai fo ang che.
• Mipui tamna hmuna kal chu a theih ang anga tihtlem rawh.
• Pawn chhuah dawnin face mask vuah thin ang che.
• Chaw tui tak, thianghlim chauh ei rawh.

Hetiang dinhmun atang hian a pum puia dam leh theih a ni em?

Ni e, a tam zawkah chuan a theih. Recovery hun chhung hi a chhanah a innghat.

A chhan chu damdawi a nih chuan damdawi ei chawlhsan atanga kar 1 atanga kar 3 chhungin neutrophil count chu a normal leh tlangpui.

A hmaa hriatchhuah leh enkawl a nih chuan he natna hi a thunun theih vek a ni. Mahse, enkawl loh chuan natna khirh tak tak leh nunna atana hlauhawm tak, sepsis ang chi natna a thlen thei a ni. Kum 65 chunglam leh thinlung, kal, lung natna dang nei te chu harsatna an tawk nasa zawk a ni.