I virus i pek damdawi kha a thawk thei lo em ni? Antiviral Resistance chungchang hi han sawi ila!

"Aw ka Pathian, doctor, he flu damdawi hian tunah hian hna a thawk lo niin a lang..." Chu chu nang pawhin i lo ngaihtuah tawh maithei, a dik em? A nih loh leh, i ṭhian emaw, i chhungte emaw, chutiang thu chu i hre tawh mai thei. Viral infection thenkhat a awm a, rei vak lo hnuah damdawi pek chu a hlawhtling lo ta hle mai. Vawiin hian antiviral resistance tih hi kan sawi dawn a ni . Hei hi thumal buaithlak tak angin a lang thei a, mahse hriatthiam a awlsam hle.

Antiviral Resistance hi eng nge ni?

A awlsam zawngin sawi ila, antiviral resistance chu virus pakhatin kan pek antiviral damdawi a chhan let loh vang a ni. Naupang nalh tak, damdawi ngaithla lo ang maiin han ngaihtuah teh. Thil thleng chu virus hian a nihna a thlak danglam thin. Tichuan a hmaa damdawi hnathawk tawh khan hri hi a thunun thei tawh lova, a nih loh leh a nghawng chu nasa takin a tlahniam ta a ni. He damdawi do thei tura lo piang chhuak virus hi enkawl a harsa hle.

He antiviral resistance hi thupui lian zawka tel a ni. Chu chu antimicrobial resistance a ni . Virus chauh ni lovin, bacteria, parasite, fungi, etc. te pawhin an enkawlna atana siam damdawi te chu an chhang let lo tan tihna a ni. Hmelmain anmahni tihhlum tumtu ralthuam atanga inthup a, mahni invenna tur kawng thar zawng chhuak ang mai a ni.

Antiviral damdawi hi eng nge ni? Engtin nge hna an thawh?

Tunah chuan i ngaihtuah mai thei, heng antiviral damdawi te hi eng nge ni ? Heng damdawi chi hrang hrang, hri kai thei thenkhat avanga natna leh hri kai enkawlna atana kan hman thin damdawi chi hrang hrangte hi a ni. Entirna tlemte chu hetiang hi a ni:

• Influenza, a nih loh leh kan tih tlangpui angin, flu.
• Genital herpes a awm thin.
• Mihring Immunodeficiency Virus, a nih loh leh HIV .

Virus thenkhat, HIV leh herpes-ah te hian heng antiviral damdawi te hian midangte hnena hri kai darh theihna chance a ti tlem a ni. Tin, a chang chuan virus i kai tih i rinhlelh emaw, i hriat chian emaw chuan damloh loh pawhin heng antiviral damdawi te hi i ei thei bawk.

Awle, tunah chuan he damdawi hian engtin nge hna a thawh tih i en ang u.

Kan taksaah virus a luh chuan kan cell hrisel chhungah a lut a, chu cell te chu hmangin a copy a siam a, chu chu virus particle tam zawk tihna a ni. Hei hi virus replicating kan ti a . Antiviral damdawi hian virus hian a copy a siam theih lohna turin hna a thawk a ni.

Heng damdawi te hian virus an do dan pakhat chu kan cell-a virus a luh theihna tur, a nih loh leh cell pakhata a innghah theihna tur tihtawp hi a ni. Ngaihtuah teh, virus hian a chenna tur leh a kai theih nan ‘in’ a mamawh a ni. Chu in chu kan cell a ni. Chuvangin, chu in chhungah chuan a lut thei lo a nih chuan virus chu a pung thei lo.

Engvangin nge heng virus te hi damdawi lakah an inven theih?

Hei hi a pawimawh ber a ni. Antiviral damdawi hian kan taksaa virus awm zat a ti tlem a, chu chu virus load a ti tlem a ni . Mahse, a tam zawkah chuan virus hi a bo vek lo va, taksaah a awm reng a ni. Chuvangin, doctor-in a tih ang chiaha damdawi i ei loh chuan, entirnan, ni engemaw zatah damdawi i ei loh chuan emaw, doctor-in a tih hmaa damdawi i ei tawh loh chuan eng nge thleng ang? Virus hi a pung leh tan ta a ni.

Virus a lo insiam chhoh zel chuan virus genetic makeup -ah inthlak danglamna a awm thei a ni . Hei hi mutating kan ti a . Miin a hmel a thlak danglam ang mai a ni.

Chutianga virus chu a inthlak lutuk a nih chuan, a hmaa antiviral damdawi hman tawh chuan he virus chi thar, chu chu virus variant hi a hre thei dawn lo a ni. Chu chu virus chu damdawi lakah a do thei ta a ni. Chumi hnuah chuan damdawi hian hri kai a titawp thei tawh dawn lo a ni.

A châng chuan, chhan hriat lohvin, virus pakhat chu a hmaa damdawi ṭha tak takte chu a chhâng thei lo thei a ni. Hei hi spontaneous resistance an ti a . Virus hian, "He damdawi hi ka la dawn lo" tiin thutlukna a siam nghal ang mai a ni.

Tu nge hlauhawm zawk?

He risk hi mi zawng zawng tan a inang vek lo. Mi thenkhat chu antiviral resistance an vei theihna chance a sang zawk a ni .

• Chronic viral infection , HIV, genital herpes, hepatitis B, emaw hepatitis C nei te chu antiviral damdawi rei tak an ei avangin an hlauhawm zawk a ni. Damdawi inang i ei chhunzawm zel hian virus hian a insiamrem theih nan hun a nei tam zawk tih hre reng ang che, a do dan tur a zawng zawk thin.
• Tin, taksa hriselna lama harsatna nei mite pawhin . Entirnan, autoimmune diseases nei te , organ transplant nei tawh te , a nih loh leh cancer enkawlna chemotherapy ang chi te hi an hlauhawm zawk a ni. An taksain natna a do theihna pianpui a tihtlem avangin, virus hi awlsam zawkin a inthlak danglam thei a, damdawi lakah pawh a do thei bawk.

Damdawi do thei virus te hi kai theih an ni em?

Ni e, vanduaithlak takin hei hi a dik a ni.Antiviral-resistant virus hi mi pakhat atanga mi dangah kai theih a ni. Hetiang dinhmun hi transmitted drug resistance kan ti a . Mi pakhatin damdawi laka inven theih virus chi khat a siam chhuak tawh ang tih han ngaihtuah teh. Chu virus chu mi dang hnenah taksa tui, semen, saliva, leh thisen inthlengna hmangin an kai thei a ni. Naupai i nih chuan i naute pawhin nau neih laiin heng damdawi laka invenna virus te hi a kai thei bawk.

He transmitted resistance chungchanga buaina chu antiviral damdawi sawi tur hi i hmang ngai lo a nih pawhin, i kai lai pawhin chu damdawi chu a la do thei tho a ni. Chutiang a nih chuan i doctor chuan antiviral damdawi dang a enchhin a ngai dawn a ni.

Engtin nge hetiang virus hi i hriat theih ang?

HIV ang chi natna i neih chuan thisen test i nei thei a, antiviral resistance i nei em tih i enfiah thei bawk . A chi hnih a awm a, chungte chu:

• Genotypic antiretroviral resistance test (GART): Hei hian HIV genes inthlak danglamna a zawng a, chu chuan damdawi laka a do thei a ni. Virus DNA-ah hian 'drug-resistant' danglamna a awm em tih enfiah ang mai a ni.
• Phenotypic antiretroviral resistance test: Hei hian HIV chi hian antiviral damdawi concentration hrang hrang a chhan dan a teh a ni. Chu chu, damdawi dose tinah virus hian eng angin nge a do theih tih a en tihna a ni.

Hei mai ni lovin, World Health Organisation (WHO) leh Centers for Disease Control (CDC) ang pawlte pawhin thisen test hmangin flu leh COVID-19 ang chi virus te chu damdawi laka an do thei tawh em tih an enfiah mek a ni.

Damdawi laka invenna virus hi engtin nge i enkawl?

Virus pakhatin damdawi a do theihna chhinchhiahna a lantir chuan i doctor chuan a dose a tipung thei a, antiviral damdawi dang hmangin a thlak thei bawk. Mahse, virus thenkhat tan chuan enkawlna pawmpui a tlem hle.

Mi thenkhat chuan chronic viral infection , HIV ang chi, nunna atana hlauhawm thei, antiviral damdawi pahnih chu a rualin an ei thin. Hei hi combination therapy an ti a . Hei hi tih a nih chhan chu virus pakhatin damdawi pahnih hi a ruala do theihna a neih theihna a tlem hle a ni. Tichuan, damdawi pakhat hian virus hi a thunun theih nan a pui thei a ni.

Hetiang dinhmun lakah hian kan inveng thei ang em?

Ni e, antiviral resistance venna tha ber chu i doctor-in a tih ang chiah, a hun taka leh a hun chhung zawnga damdawi ei hi a ni. Hei hi a pawimawh hle.

I phone ah i ti thei ang.Nitin hun khata i damdawi ei tur hriattirna siam rawh. Dose i miss a nih chuan i doctor hnenah engtin nge i tih ang tih zawt rawh. I hriatreng veleh i ei a ngai mai thei.

Antiviral damdawi hi nunna atana hlauhawm thei virus infection control nana kan hmanraw lian ber pakhat a ni. Heng damdawi te hian virus pung zel tur leh symptoms siamna tur a titawp thin.

Chuvangin, i doctor-in a sawi ang chiaha damdawi i ei loh chuan virus hi a active leh thei a, a pung thei bawk. A pung zel chuan virus hi a danglam thei a, i damdawi ei pawh a thawk thei lo mai thei. Antiviral resistance i neih chuan i doctor chuan damdawi emaw, a dose emaw a thlak a ngai mai thei. Chuvangin, i doctor thupek dik taka zawm a pawimawh.

A tawi zawnga hriat reng tur tlemte (Take-Home Message)

Okay, chuvangin kan sawi tawh atang hian thil pawimawh tak tak thenkhat chu awlsam zawka i hriatreng theih nan i khaikhawm ang u:

• Antiviral resistance chu virus pakhatin a damdawi pek a resistant a nih chuan a ni.
• Hei hi a chhan ber chu doctor-in damdawi a pek ang chiah, a hun chhung zawnga ei loh vang a ni.
• Hetiang hlauhawmna hi hun rei tak chhunga hri kai tawh, HIV, herpes, leh hepatitis te tan a sang zawk a, taksa hriselna chak lo nei tan pawh a sang zawk bawk.
• Damdawi laka invenna virus chu mi pakhat atanga mi dangah kai theih a ni.
• Chumi laka inven dan tha ber chu doctor thupek dik taka zawm hi a ni. Damdawi hi a hun takah, a dose dik takah leh a hun takah ei a pawimawh hle.
• Damdawi chungchanga zawhna emaw rinhlelhna emaw i neih chuan i doctor nen inbia ngei ang che.

He thu hi i tan a tangkai ngei ka beisei. Hrisel takin awm rawh!

` Antiviral Resistance, Antiviral Drugs, Viral Infection, HIV, Influenza, Damdawi laka invenna, Damdawi laka invenna