Autosomal Dominant Polycystic Kidney Disease, thlahtute atanga lo chhuak, kal chhunga cyst awm thin chungchang hi han sawi ila.

I hnungzang emaw, i sir emaw-ah natna i tuar reng emaw, doctor-in i thisen sang a sang deuh niin a sawi emaw ang maiin han mitthla teh. Heng thilte hi thil pangngai anga ngaihin kan theihnghilh fo thin. Mahse a chang chuan heng thil hnuaia thup hi kal (kidney) nena inzawm buaina, ngaihven engemaw zat a ngai thin. Vawiin hian chutiang dinhmun kan sawi a, chu chu uluk taka enkawl a nih chuan uluk taka thunun theih a ni.

A awlsam zawngin ADPKD chu eng nge ni?

Hei hi Autosomal Dominant Polycystic Kidney Disease , a tawi zawngin ADPKD kan ti a. Thil thleng chu i kal chhungah hian tuiin a khat bawm te tak te, cysts tih te hi a tam hle a ni. Heng cyst te hi an lo thang lian tan chuan kidney te hian an hna pangngai thisen tihfai dan tur an thawk thei lo.

Hei hian hriselna lama harsatna a thlen thei a, chu chu thisen sang , zun kawng infection , leh kal (kidney stone) te a ni. Mi thenkhatah chuan he natna hi hun kal zelah a zual thei a, kal (kidney failure) pawh a thlen thei. Mahse, mi zawng zawngah a thleng lo.

Thil tam takah chuan miten natna an vei tih hre lovin kum tam tak an dam thei a ni. Kum 30 leh 40 inkar atanga a lan chhuah tan tlangpui a, chuvang chuan "adult PKD" an ti bawk.

He natna lan chhuah dan engte nge ni? Engtin nge kan awm?

ADPKD vei zawng zawng hian symptom an nei vek dawn lo. Mi thenkhat chuan kum tam tak chhung chu an nei tih an hre lo mai thei. Hetiang natna vei zingah hian a lan chhuah tam ber chu thisen sang , zun kawng infection tam tak leh kal ( kidney stone ) te hi a ni Heng symptoms te hi i titawp ang u.

Hun a kal zel a, heng cyst te hi a lianin kal a tichhe thei a, mi thenkhatah chuan kal a tichhe thei a ni. Chutiang a nih chuan symptoms te chu:

• Chau leh hah lutuk tih hriatna ( Fatigue ) .
• Zun chhuah a ngai fo thin
• Hmeichhiaah thlasik hun mumal lo
• Nausea leh luak chhuak
• Thâwk harsa
• Ke ruh, kut leh ke a hring chhuak
• Mipaah ​​chuan erectile dysfunction a awm thin

Engvangin nge hetiang natna hi a lo awm? Hrilhfiahna a ni em?

Ni e, hei hi thlahtu natna a ni . A awlsam zawngin sawi ila, he natna hi kan taksaa genes (genes) a chhiat vang a ni. A dik zawka sawi chuan gene pahnih `PKD1` leh `PKD2` an tih zinga pakhat a chhiatna avanga lo awm a ni. Heng genes te hi kidney cell te hnenah "engtikah nge an lo thanglian dawn" tih signal petu an ni. Chuvangin heng gene pakhatah hian chhiatna a awm chuan kal cell te chu thunun theih lohvin a thang lian a, kan sawi tak cyst te chu a lo piang tan thin.

Hriselna lama natna tam zawk a lo awm theih nan chuan i nu leh pa te hnen atangin gene chhia chu i rochun a ngai a ni. Mahse ADPKD chungchanga thil danglam tak chu he gene chhia hi nu leh pa pakhat chauh, i nu emaw i pa emaw atanga i rochun chuan i fa hian natna hi a nei ang.

A tlem hle a, mi pakhatin a nu leh pate hian natna hi an nei lo a nih pawhin a vei thei a, mahse an taksaa gene pakhata chhiatna thar a awm vang pawh a ni thei. Mahse, hei hi a tlem hle.

He natna hi Doctor hian engtin nge a hriat chian?

I doctor chuan i natna lan chhuah dan azira kal lama harsatna i nei thei nia a ngaih chuan, nephrologist hnenah a refer thei che a ni . Zawhna a zawt ang che:

• I symptoms te chu engte nge ni? Engtik lai khan nge an tan?
• I thisen sang i hria em?
• Khawiah mah hrehawmna a awm em? A nih chuan khawiah nge a awm?
• I chhungte zingah kal natna nei an awm em?
• Genetic test i nei tawh em?

Tichuan, kal (kidney)-ah hian cyst a awm leh awm loh enfiah nan test eng emaw zat an nei leh thin.

• Ultrasound Scan: Hei hian sound wave hmangin kal (kidney) thlalak a siam a. Hei hi test hmasa ber a ni fo thin.
• MRI Scan emaw CT Scan: Heng scan complex zawk hmang hian ultrasound hmanga hmuh theih loh khawpa cyst te chu an hmuchhuak thin.

Tin, i DNA chu `PKD1` emaw `PKD2` genes-ah chhiatna i neih leh neih loh test theih a ni bawk. Mahse, he test hian natna i neih leh neih loh a hriat theih laiin, engtikah nge symptoms a lan dawn tih leh engtiang chiahin nge a nasat dawn tih erawh a sawi lawk thei lo.

Inenkawl lai leh in lamah eng nge kan tih ang?

ADPKD hi damdawi a awm lo. Amaherawhchu, he natna avanga hriselna lama harsatna awmte hi enkawl theih a ni a, kal (kidney failure) hi ven emaw, tihkhawtlai emaw theih a ni. Enkawlna i mamawh mai thei a, chungte chu:

• Kidney failure kal zelna tikhawtlai thei damdawi: Tolvaptan (Jynarque) ang damdawi hian puitling, natna vei chak zawka awmte kal hnathawh tlahniam chu a thunun thei a ni.
• Thisen sang damdawi: Thisen sang control hi a pawimawh hle.
• Urinary tract infection tan antibiotics hman tur a ni
• Natna tihdamna damdawi

I kal (kidney) a chhiat chuan dialysis i tih a ngai dawn a ni . Hei hian machine hmanga i thisen tihfai a huam a ni. Kidney transplant pawh i dawng thei bawk . Hei hi i tan a tha em tih hriat nan i doctor nen in sawiho tur a ni.

Hrisel taka kan awm theih nan kan zawm tur tih dan

I kal (kidney) venhimna tur leh a rei thei ang bera hnathawh that theih nan nun hrisel neih a pawimawh hle.

• Eat dik: Chaw ei tur inthlau tak, chi tlem zawk ei thin ang che. Chi (salt) hian thisen sang a tisang thei a ni.
• Active takin awm rawh:Exercise hian i taksa rihna leh thisen sang a thunun thei a, mahse i kal (kidney) tichhe thei contact sport hi pumpelh rawh.
• Meizial zuk loh: Meizial hian kal (kidney)-a thisen kalna kawng a tichhe thei a, cyst siam theihna a tipung bawk.
• Tui in tam: Dehydration hian cyst siam theihna a tipung thei.

Hmalam pan zelin eng nge kan beisei theih ang? Complication dang a awm em?

Cyst hi a lo thang zawi zawi hle fo thin. I thisen sang i thunun a, nun hrisel i hman chuan he thanlenna hi i thunun thei a ni. Mahse kum tam tak chhung chu i kal (kidney) tichhe thei khawpin an lian thei a ni.

Natna a zual zel dan pawh hi eng gene nge i neih (PKD1 emaw PKD2 emaw) ah a innghat bawk. A tlangpuiin PKD1 gene defect nei te hi PKD2 gene defect nei te aiin kidney failure vei an tam zawk.

ADPKD hian hriselna lama harsatna dang a thlen thei bawk.

Hetiang natna nena kan nun hian rilru chak taka awm reng a pawimawh. Hemi chungchang hi i chhungte leh i thiante nen sawiho rawh. Tin, i doctor nen inbiak reng la, a thurawn dik tak zawm bawk ang che.