I doctor chuan Avapritinib tih damdawi a pe che em? I rilruah zawhna tam tak i nei ngei ang, chu chu eng natna atan nge hman a nih, i hman laiin eng fimkhur tur nge tih leh a nghawng tha lo a awm em tih te hi a ni. Lungngai suh. Vawiin hian he damdawi chungchang hi i hriatthiam theih tur khawpa awlsam takin kan sawi dawn a ni.
Avapritinib hi eng damdawi nge ni?
A awlsam zawngin Avapritinib hi damdawi hmasawn tak a ni a, cancer cell-a protein thenkhat target-in, chu cancer cell-te thanna chu a titawp a ni. Hei hi "targeted therapy" kan ti a ni. Sniper ang bawkin he damdawi hian cancer cells te chu a zawng chhuak a, a than dan a control a, chutih rualin cell hrisel tam thei ang ber a humhim bawk.
He damdawi hi natna pahnih enkawlna atan hman a ni ber a:
1. Systemic Mastocytosis: Hei hi taksaa cell chi khat `mast cells` an tih te a lo thang dan pangngai lo avanga lo awm a ni.
2. GISTs (Gastrointestinal Stromal Tumors): Hei hi cancer chi khat bik a ni a, kan chaw ei dan (intestines) ah a awm thin.
Damdawi ei tan hmaa doctor hnena i hrilh tur thilte
Avapritinib i ei tan hmain a hnuaia thilte hi i doctor hnenah chiang taka i hrilh hmasak phawt a pawimawh hle .
- Tun hmaa thluaka thisen chhuak emaw stroke emaw i neih tawh chuan .
- Thisen kalna kawng bang bulging emaw chak lo emaw i nei tih i hriat chuan.
- I thisen platelet level a hniam chuan .
- Avapritinib emaw damdawi dang emaw, ei tur emaw, dye dang emaw allergy i neih chuan.
- If you are pregnant , emaw naupai thuai tum i nih chuan.
- Nu hnute pe lai i nih chuan .
Heng thu hriatte a\ang hian i doctor chuan he damdawi hi i tan a tha em tih emaw, fimkhur bik taka pek tur nge tih emaw a rel ang.
Engtin chiah nge he damdawi hi ka hman ang?
Damdawi pakhat atanga hlawkna tam ber hmu tur chuan a hman dik a pawimawh hle.
- Hei hi tablet angin a lo thleng a ni. Tablet chu tui glass khat nen a pumin ei tur a ni . Tablet chu chew, crush, tihchhiat ngai suh.
- He damdawi hi pum ruak a ei tur a ni. Chumi awmzia chu, chawhmeh ei hma darkar khat emaw, chawhmeh ei hnu darkar hnih emaw tal ei tur a ni. Chaw ei rualin ei suh.
- He damdawi hi grapefruit tui nen ei ngai suh, grapefruit tui hian he damdawi hnathawh dan a nghawng thei a ni.
- Damdawi hi nitin, a hun ruatah leh hun bituk chhungin ei thin tur a ni.
- Doctor thurawn tel lo chuan damdawi ei kha titawp thut suh.
Accident-a i in tam lutuk chuan engtin nge ni ang?
Dose rawt aia tam i ei nia i hriat chuan hlauthawng suh la, Colombo National Hospital-a National Poisons Information Center chu call nghal rawh. A nih loh leh damdawi in hnai ber Emergency Treatment Unit (ETU)-ah kal rawh.
Damdawi dose i ei loh chuan engtin nge i tih ang?
Dose i ei theihnghilh chuan i hriatreng veleh ei nghal rawh. Mahse, i dose leh tur thleng darkar 8 aia rei lo a nih chuan missed dose kha skip la, i dose leh tur chu a hun ruatah ei rawh. Eng thil vang pawhin vawi khatah vawi hnih ei loh tur.
Damdawi dang nena inzawmna a awm thei em?
Ni e, Avapritinib hian damdawi dang thenkhat, herbal products, leh i ei tur ei tur te nen a inzawm thei a ni. Damdawi i ei zawng zawng hi doctor hnenah hrilh vek a pawimawh hle.
A hnuaia tarlan te hi Avapritinib nena inzawm thei thil thenkhat tarlan a ni.
| Damdawi/chaw chi hrang hrang | Entirnan |
|---|---|
| Antibiotics thenkhat | clarithromycin, erythromycin tih te hi a ni |
| Fungal infection damdawi | fluconazole, itraconazole, ketoconazole te a ni |
| HIV emaw Hepatitis emaw tan antiviral thenkhat pek thin | Doctor hnenah zawt rawh. |
| Epilepsy (fits) damdawi thenkhat . | carbamazepine, phenobarbital, phenytoin tih te hi a awm a |
| Damdawi dang | cyclosporine, diltiazem, verapamil, rifampin te a awm bawk |
| Herbal atanga siam chhuah a ni | Mithianghlim Johana Wort |
| Chaw | Grapefruit tui tak a ni |
He list hi a kimchang lo hle a, chuvangin damdawi, vitamin, herbal remedies leh supplement i ei zawng zawngte chu i doctor hnenah hrilh vek ang che.
Damdawi ei huna hriat reng tur thil
- Medical check-up neih fo tur: He damdawi result hi a lan theih nan hun engemaw chen a la ngai thei. Chuvangin doctor thurawn angin ni ruat saah clinic-ah kal la, i dinhmun enfiah rawh.
- I ha leh i hmui enkawl rawh: He damdawi hian thisen chhuah theihna a tipung thei a ni. Chuvangin ha i sil leh flossing hunah fimkhur rawh. Ha enkawlna (ha lakna ang chi) i neih chuan he damdawi hi i ei tih hi i ha enkawltu hnenah hrilh ngei ang che.
- Mutthilh leh luak chhuak: Mutthilh emaw, luak chhuak emaw i nei thei. Chuvangin, he damdawi hian engtin nge a nghawng che tih chiang taka i hriat hma chuan lirthei khalh emaw, machinery emaw hman loh tur a ni. Thutna atanga tho thut suh.
- Naupai leh fate: Hei hi thil pawimawh tak a ni.
- Hmeichhia: He damdawi ei lai leh damdawi ei chawlhsan hnu kar 6 chhung chu naupai loh tur a ni.
- Mipa: He damdawi ei lai emaw, damdawi ei chawlhsan hnu kar 6 chhung emaw fa neih tum suh.
- He thurawn hi pek a ni a, a chhan chu nausen piang lai tan hian harsatna lian tham a thlen theihna a awm a ni.
- Nau hnute pek: He damdawi hi i ei lai leh i ei zawh hnu kar 2 chhung chu naute hnute pe suh.
- Fertility: He damdawi hian fa neih theihna a nghawng thei a ni. Hemi chungchangah hian ngaihtuahna i neih chuan i doctor nen zalen takin sawi rawh.
Side effect awm thei te chu engte nge ni?
Damdawi dang ang bawkin Avapritinib hian side effect engemaw zat a nei thei a ni. Chung zinga ṭhenkhat chu thil pawi tak a ni thei a, chuvangin fimkhur a pawimawh hle.
| Side Effect a awm thei | Hrilhfiahna |
|---|---|
| Side effects te chu doctor hnenah hriattir nghal tur a ni | |
| Allergy natna a awm thei | Vun vun rawng, hnim hring, hmai, hmui emaw lei emaw a hring. |
| Stroke natna lan chhuah dan | Mit danglam, buaina, tawng leh hriatthiam harsa, lu na na tak, hmai, kut emaw ke emaw rang emaw chak lo emaw, kal harsa, luak chhuak. |
| Rilru lam inthlak danglamna | Mood inthlak nghal, thil awm lo hmuh leh hriat (hallucinations). |
| Thisen chhuah emaw, hliam emaw danglam tak | Sawifiah loha vun a hliam, hmui thisen chhuak. |
| Luak chhuak | Luak chhuak nawn leh thin. |
| Side effects te chu a awm reng emaw, a buaithlak emaw a nih chuan doctor hnenah hriattir tur a ni | |
| Digestive system lama harsatna awm thei | Constipation, luak chhuak, pum na, luak chhuak. |
| Thil dang natna tlanglawn tak takte | Chaw ei chak lohna, hah lutuk, kut, ke leh ke ruh a hring. |
He list-a tarlan loh symptom dang danglam tak i neih chuan i doctor hnenah pawh hrilh bawk ang che.
Engtin nge damdawi i dahkhawm leh i paih thin?
- Damdawi hi naupang leh ran vulhte hmuh theih lohna hmunah dah tur a ni .
- Room temperature (20-25 degree Celsius inkar) ah dah tur a ni.
- Damdawi expired hman loh tur.
- Damdawi hun kal tawh emaw, duh loh emaw paih dan tha ber chu doctor zawt rawh. Bawlhhlawhah paih a him a nih chuan, pill chu a bawm atang chuan la chhuakin, tea hnah hman tawh, coffee ground emaw, lei emaw ang chi thil nen chawhpawlh la, bag khar nghet takah dah la, paih rawh.
Take-Home Thuchah a ni
- Avapritinib hi damdawi bik, hmasawn tak a ni a, cancer cells te a target a ni.
- He damdawi hi pum ruak ah ei fo thin ang che . Grapefruit tui nen ei ngai suh.
- Damdawi dang leh supplement i ei zawng zawngte chu i doctor hnenah hriattir a pawimawh hle.
- Stroke chhinchhiahna (hmai/kut hring, tawng harsa), emaw thisen chhuah danglam tak tak ang chi side effect na tak i neih chuan doctor pan nghal rawh.
- Damdawi ei lai leh ei zawh hnu hun engemaw chen chu naupai (hmeichhia leh mipa) pumpelh tur a ni.
- I damdawi ei kha bansan suh la, i doctor thurawn tel lo chuan a dose pawh thlak suh. A thupekte chu zawm fo ang che.
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