Engtin nge kan ruh te, kan ruh te, kan vun te, leh kan taksa peng hrang hrangte hi a felfai taka vawn tlat a nih tih i ngaihtuah ngai em? Cement hmanga in sak ang bawkin kan taksa peng zawng zawng hi tissue chi khat bik hmanga inzawmkhawm leh thlawp vek a ni. Hengte hi "Connective Tissues" kan ti a. Hengte hi kan taksa ‘glues’ te an ni. Chuvangin, kan taksa hmun tina kan hmuh theih connective tissue te nghawng thei natna te hi " Connective Tissue Diseases" tih mai a ni.
A awlsam zawngin, he connective tissue hi eng nge ni?
Ngaihtuah teh, hengte hi kan taksa chhungril lam (internal framework) a ni. Anni tel lo chuan kan taksa chu a tlakbuak ang. He category connective tissue zingah hian:
- Bones: Kan taksa pianzia leh chakna petu framework nghet tak.
- Cartilage: Ruh pahnih inzawmkhawm lohna tur ruh inkar tissue smooth tak a ni. Kan hnar leh beng ah pawh hetiang hi kan nei ve bawk.
- Tendons: Thil chak tak, band ang chi, ruh leh ruh inzawmkhawm.
- Ligaments: Ruh inzawmkhawmtu leh ruhkawr ti nghettu peng.
- Vun: Kan taksa khuhtu leh vengtu taksa peng lian ber a ni.
- Taksa thau: Taksa peng hrang hrang, chakna khawlkhawmtu leh taksa peng hrang hrang venghimtu.
- Fascia: Taksa leh taksa peng hrang hrang hual veltu membrane te tak te.
I hmu em, heng tissue te hi kan taksa zawng zawngah, hmun tinah a awm vek a ni. Chuvangin connective tissue natna a lo awm chuan taksa hmun khatah chauh a awm lo va, hmun tam tak a nghawng thei a ni. A châng chuan tissue chi khat chauh a nghawng a, a châng chuan tissue chi hrang hrang, taksa peng hrang hrang thlengin a nghawng bawk.
Heng natna chi hrang hrangte hi engte nge ni?
Tunah hian connective tissue natna chi hrang hrang hriat chhuah 200 chuang a awm a, mahse chi thum ah kan then thei a ni.
1. Autoimmune diseases: Mahni taksa invenna (immune system) in kan taksa peng hrang hrang a beih avanga natna lo awm.
2. Genetic disorders: Natna pian tirh atanga lo awm leh genes a chhiatna avanga lo awm.
3. Cancer: Connective tissue-a awm cancer. Hengte hi (Sarcomas) kan ti a ni.
Tunah chuan heng chi hrang hrangte hi chipchiar deuhin han thlir ila.
1. Autoimmune Connective Tissue natna te
Hei hi mi tam zawkin "connective tissue disease" an tih hian an hriat leh an sawi thin chi a ni. Hetah hian thil mak tak mai a thleng thin. Kan taksa natna laka humhim tur "sipai" ang maia awm, immune system hian kan taksa hrisel connective tissue te chu tihsual ang maiin a rawn bei tan ta a ni. Hei hian chutiang tissue-ah chuan chronic inflammation, a nih loh leh swelling a thlen thin.Hei hian hun rei tak a awm chuan natna a thlen thei a, a hring thei a, a tawpah chuan chu tissue te chu a tichhe vek thei a ni.
A awlsam zawngin hetianga thil thleng hi kan security guard-te ngeiin kan in ngei pawh an bei ang mai a ni.
A hnuaiah hian he category-a tel natna lian ber ber thenkhat tarlan a ni.
| Natna hming | Hrilhfiahna mai mai a ni |
|---|---|
| Rheumatoid arthritis natna a ni | Hei hian ruhkawr a nghawng ber a ni. A ruhte chu a hring a, a khauh bawk a, zing i thawh chuan i kut zungtang i ben thei lo mai thei. Hun a kal zel a, a ruhte a chhe thei a, kut zungtang pawh a hrual thei bawk. A chang chuan he hliam hi taksa peng dang, thisen kalna leh lungah te pawh a darh thei bawk. |
| Lupus a ni | Hei hi natna buaithlak tak a ni. Lupus hian taksa chhunga connective tissue eng pawh a nghawng thei a ni. Tin, taksa peng lian tak tak vun, ruh, thinlung, lung, kal, leh thluak te pawh a tichhe thei bawk. A sen, butterfly ang maia lang hi a natna lan chhuah dan hriat lar tak a ni. |
| Scleroderma a ni | Hei hi taksain a mamawh aia tam Collagen an tih protein a siam chhuah hun a ni. Hei hian vun a ti thim a, a ti nghet a, a ti hring bawk. Hei hian chhungril peng hrang hrang, lung, thinlung leh chaw ei kawng te pawh a nghawng thei bawk. |
| Sjögren-a natna (syndrome) a ni | Hetah hian immune system hian taksaa tui siamtu glands te chu a bei thin. Chu chu hmui leh mittui siamtu glands te hi a ni. Chuvangin a natna lan chhuah dan ber chu mit vawt leh hmui vawt hi a ni. Hetianga a vawt hian vun, hnar leh kawr a nghawng thei bawk. |
| Myositis natna (Myositis) a ni | He natna hian ruh (muscle) a nghawng a. Muscle te chu a lo hring a, a chak lo bawk. Chair atanga tho emaw, stairs chhoh emaw chu a harsa ta hle. A chi thenkhatah chuan taksa ruh bakah hian vunah eczema a awm thei bawk. |
A châng chuan mi pakhatin heng natna engemaw zat chhinchhiahna a nei dun thei a ni. Hei hi Mixed Connective Tissue Disease kan ti a . A dang erawh chuan symptoms a awm a, mahse natna bik anga chiang taka thliar hran theih a ni lo. Hei hi Undifferentiated Connective Tissue Disease kan ti a .
2. Genetic Connective Tissue lama harsatna awm thei
Heng natnate hi keimahni immune system a malfunction vang a ni lo. Hengte hi kan pianpui dinhmun a ni a, kan genes-a mutation avanga lo awm a ni. He genetic defect hian connective tissue siam dan a tidanglam thin. Hei hian heng tissue a protein pahnih collagen leh elastin te siam chhuahna a nghawng ber a ni . Collagen hian tissue te chu chakna a pe a, elastin hian flexibility a pe bawk.
| Natna hming | Hrilhfiahna mai mai a ni |
|---|---|
| Marfan syndrome a ni | Hei hian elastin fibers a nghawng a, tissue chu a stretch lutuk a, a loose lutuk bawk. Heng mite hi a tlangpuiin a sang lo hle a, ke leh kut zungtang sei tak tak an nei a ni. Hei hi thinlung thisen kalna bulpui (aorta) a nghawng theih avangin ngaihtuah tur a ni. |
| Ehlers-Danlos natna (EDS) natna hi a awm lo. | Hei hian collagen a tichak lo va, vun chu a ti hrual lutuk a, ruh chu a ti flexible lutuk (double-jointed ang chi), a ti chhe hle bawk. Joints a crack fo a, hliam te pawh a dam rei zawk. |
| Osteogenesis a famkim lo | Hei hi a hming dang chu "brittle bone disease" tih a ni. Hetiang dinhmunah hian collagen chi khat tlakchham vangin ruh a chhe awlsam hle. Tlu tenau pawh hian ruh tliak a thlen thei. Mit var pawh a rawn lang thei bawk. |
He genetic disorder neia piangte symptoms hi a inang lo hle. Ṭhenkhat chuan symptoms na lo tak tak an nei thei a, ṭhenkhat erawh chuan harsatna lian tak, nunna atana hlauhawm tak tak an nei thei thung. He genetic defect hi damdawi a awm loh avangin doctor-te chuan a natna lan chhuah dan leh harsatna lo awmte chauh an enkawl thei a ni.
3. Connective tissue cancer (Cancers - Sarcomas) 1. A rilru a hah lutuk chuan a rilru a buai em em a.
Sarcoma hi cancer chi khat a ni a, connective tissue atanga intan a ni. Chungte chu ruh, ruhkawr, thau, thau, ruhkawr, leh ligament-ah te a awm thei.
Hengte hian a tir lamah chuan symptom an nei lo tlangpui. Simptoms hi tumor a lo lian a, a bula organ emaw thisen kalna kawng emaw a press chauhvin a lang thin. A châng chuan ruh natna emaw, ruh natna emaw angin a inṭan thei bawk. Ṭhenkhat chu vun hnuaia lump angin a lang thei bawk. Hetiang cancer chi hi taksa peng dangah pawh a darh thei bawk. Entirna thenkhat chu osteosarcoma (ruh cancer) leh liposarcoma (thau cancer) te an ni.
Heng natna lan chhuah dan tlangpui chu engte nge ni?
Heng natna chi hrang hrang a tam em avangin, a lan chhuah dan pawh a inang lo hle. Mahse, thil inang tlemte kan hmuchhuak thei.
- Taksa pumpuiah natna: A bik takin ruh leh ruhkawr ah natna leh ruh na hi a awm fo thin.
- Chak lo leh hah: Chhan hriat loha chau lutuk hi heng natna tam tak chhinchhiahna a ni.
- Respiratory leh cardiovascular system lama harsatna: Kan lungah hian connective tissue tam tak a awm a. Tin, thisen kalna kawngte chu he tissue kaltlangin a kal avangin hmun khatah inflammation hi awlsam takin heng taksa peng hrang hrangah hian a darh thei bawk. Hei hian thawk harsatna a thlen thei a, heart rate a tidanglam thei bawk.
- Thisen kalna kawng a hring: Thisen kalna kawng a lo hring a nih chuan a puak darh thei a, taksa chhungah thisen a chhuak thei a ni.
A pawimawh ber chu, a ruala inzawm lo anga lang symptom engemaw zat (entir nan, ruh natna, hmui vawt, leh vun hring) i neih chuan natna pakhata thil danglam tak a ni thei. Chuvangin ngaihthah suh.
Heng natnate hi a chhan bik a awm em?
Dik tak chuan scientist-te chuan heng natna tam tak awm chhan dik tak hi an la hmu chhuak lo. Thil thleng chu kan taksaah hian thil engemaw takah malfunction a awm a ni. Autoimmune natnaah chuan immune system a thawk tha lo. Genetic disease-ah chuan genes-ah malfunction a awm a. Cancer-ah chuan cell te chu thunun theih lohvin an inthen tan thin.
Heng chhiatnate hi engvangin nge a awm tih chiang taka sawi theih ni lo mah se, risk factor thenkhat chuan hetiang hi a thlen tih hmuhchhuah a ni.
- Infection na tak tak avanga immune system overactive lutuk.
- Chemical tha lo thenkhat nena inzawmna.
- Chhungkaw history-a heng natna (hereditary factors) nei tawh.
He natna hi engtin nge doctor hian a hriat theih ang?
I symptoms te nen i doctor i pan hunah i medical history leh family medical history te a zawt hmasa ang che. Chumi hnuah chuan taksa enfiahna a nei ang a, test engemaw zat nei turin a refer thei che a, a tul angin.
- Thisen test: C-reactive protein (CRP) leh ESR ang chi test hmangin taksaa inflammation awm leh awm loh enfiah a ni. Autoimmune natna hriat theihna turin antibodies bik an enfiah bawk.
- Imaging test: X-ray leh MRI scan hian ruh, ruh leh soft tissue te chhiatna a hriat theih nan a pui thei a ni.
- Tissue biopsy: Vun te tak te emaw, a nghawng dang emaw lak a, microscope hmanga enfiah.
- Mit leh hmui a vawt leh vawt loh enfiah: Heng test te hi Sjögren’s syndrome ang chi natna rinhlelh a nih chuan tih thin a ni.
Hei hi eng enkawlna nge ni?
Connective tissue natna tam tak hi dam chhung zawnga awm thin a ni . Chumi awmzia chu tihdam kim a harsa tihna a ni. Chuvangin, doctor-te thil tum ber chu natna nasatzia tihziaawm te, symptoms control te, harsatna lo thleng tur venna te, nun pangngaia nunpui tura tanpui te hi a ni.
Autoimmune natna leh cancer te hi a chang chuan remission ah a kal thei a, chu chu natna inactive leh symptoms awm loh hun chhung tihna a ni. Mahse an lo lang leh thei bawk.
- Autoimmune natna tan: Immune system hnathawh tam lutuk control nan anti-inflammatory drugs (corticosteroids) leh immunosuppressants pek thin a ni.
- Cancer (sarcomas) tan chuan: Surgery hmanga tumor lakchhuah, chemotherapy, leh radiation therapy te hman a ni.
- Genetic natna tan chuan:Chungte chu a lan chhuah dan azirin enkawl an ni. Entirnan, natna tidamtu damdawi an pe a, lung lam harsatna tan damdawi an pe bawk.
In almost all of these diseases , physical therapy leh doctor thurawn hnuaia exercise dik tak tih hi natna control nan leh ruh leh ruh hnathawh tha tak neih reng nan a pawimawh hle.
Take-Home Thuchah a ni
- Connective tissue diseases hi natna chi hrang hrang, kan taksa inzawmkhawmtu tissue te nghawngtu a ni. Kan taksa peng eng pawh a nghawng thei a ni.
- Heng natnate hi chi thum-ah then a ni ber a, chungte chu autoimmune, genetic, leh cancer (sarcoma) te an ni.
- Symptom pakhat aia tam i neih chuan lungngai rawh, chu chu ruh natna, hah lutuk, vun inthlak danglam, leh thawk harsa tih te hi a ni.
- Heng natna tam tak hi tihdam kim theih ni lo mah se, enkawl dan dik leh nunphung tihdanglam a nih chuan a natna lan chhuah dan chu thunun theih a ni a, nun tha tak a awm thei a ni.
- Heng symptoms te hi i neih chuan doctor pan ngei ngei tur a ni. Hriatchhuah hmasak hi enkawlna hlawhtling takah a pui hle.
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