Cortisol chu eng nge ni? Engtin nge i taksa a nghawng?

‘Cortisol’ tih thumal hi i hre tawh ngei ang, a bik takin ‘stress’ chungchang sawi hian. Mahse, i hria em, ‘stress hormone’ mai a ni lo? Cortisol hi kan taksaah hormone pawimawh tak a ni. Dik tak chuan kan taksa peng leh tissue zawng zawng deuhthaw hian a nghawng a ni.

Cortisol hi eng nge ni tak tak?

A awlsam zawngin sawi ila, cortisol hi i adrenal glands – i kal chunga awm gland te tak te pahnih atanga siam leh chhuah hormone a ni. Hormone class pakhat glucocorticoids , steroid hormone an tih zingah a tel a ni.

Hei hi stress atan chauh a pawimawh i ti mai thei. Mahse, a ni lo. Cortisol hian hna pawimawh dang tam tak a nei a. Entir nan:

• Kan taksain chakna atâna sugar, a nih loh leh glucose , a hman dân a thunun a ni.
• Taksa chhunga inflammation a tihziaawm.
• Thisen sang a control thin.
• Kan mut leh harh cycle vawng reng turin a pui a ni.

Kan taksa hian he cortisol level hi a enfiah reng a, a level nghet takah a dah a, chu chu homeostasis dinhmunah a dah a ni . A chhan chu cortisol level sang emaw hniam emaw pawh nise kan hriselna atan a tha lo.

Chuti a nih chuan cortisol hi ‘stress hormone’ a ni tak tak em?

Ni e, cortisol hian a takah chuan kan taksain stress a hmachhawn danah hmun pawimawh tak a chang a ni. Cortisol hi stress chi hrang hrang i neih chuan a chhuak thin a, chungte chu:

• Acute stress – Ui rawn um nghal mai ang maiin ngaihtuah rawh.
• Chronic stress – entirnan, hnathawhna hmuna harsatna awm reng emaw, chhungkaw harsatna emaw.
• Traumatic stress – ngaihtuah phak loh thil thleng tawn ang chi.

Mahse, ka sawi tawh ang khan cortisol hian stress-a puih mai ni lovin tih tur tam tak a nei a ni.

Engtin nge cortisol hian ka taksa a nghawng?

Cortisol hian kan taksa chhunga organ system zawng zawng deuhthaw a nghawng a, hna pawimawh engemaw zat control turin a pui bawk.

Kan taksain stress a dawn dan control

Kan stress hian kan taksa hian ‘fight or flight’ response nena inzawm hormone, adrenaline -te chu a tichhuak hmasa thin. Tichuan cortisol chu a chhuak ta a ni. A chhan i hria em? Kan inring reng theih nan. Cortisol hian kan liver hian glucose , chu chu sugar a chhuah tir bawk. Hei hian stress kan neih laiin chakna min pe nghal vat thin.

Metabolism leh thisen sugar control

Thilsiam (metabolism) a awmA awlsam zawngin kan taksa chhunga nung leh hnathawhna atana min puitu chemical process zawng zawng hi a ni. Heng thil thleng sang tam tak hi kan taksaah hian a thleng fo thin.

Cortisol hian kan taksain glucose chu chakna atana a hman dan a thunun avangin he metabolism hi a nghawng a ni. Hei hi kawng hrang hrangin a ti thin. Entirnan, cortisol hian kan pancreas chu insulin siam chhuah tihtlem leh glucagon siam chhuah tipung turin a hrilh a. Insulin hian thisen sugar a tihniam a, glucagon hian thisen sugar a tisang bawk. Hrethiam e?

Chu mai ni lovin, cortisol hian kan taksa chhunga tissue dang engemaw zat a nghawng bawk a, glucose hman dan a control bawk. Chung zingah chuan:

• Adipose tissue – chu chu taksaa thau awm tihna a ni.
• Thin
• Tihrawl

Inflammation tihtawp nan

Hun rei lote chhungin cortisol hian inflammation , taksaa hring leh sen hring hi a tihziaawm thei a, kan taksa hriselna a tichak thei bawk. Mahse, i taksain hun rei tak chhung cortisol level sang tak a neih chuan i taksa hian a insiamrem thei a ni. Thil thleng thei chu inflammation a pung a, i immune system a chak lo.

Thisen sang control dan tur

Mihring thisen sang cortisol hian engtin nge a tihregulate tih chiang taka hriat a la ni lo. Mahse, cortisol level a san lutuk chuan thisen sang a thlen thei a ni. Chutiang bawkin cortisol level a hniam lutuk chuan thisen sang a ti hniam thei a ni.

Mut-harh cycle tihregulate-na tura puitu

Mi tam zawk chuan zan lama an mut hian cortisol level an nei tlem hle. Zingkar an thawh hma lawk hian cortisol level a sang ber thin. Hei hian cortisol hi kan circadian rhythm nen a inzawm tlat tih a tilang a, chu chu kan taksa hnathawh dan leh nitin hun a zirin kan harh dan a ni.

Engtin nge ka taksa hian cortisol level a control theih?

Kan taksa hian cortisol level control na tur system complex tak a nei a. I hypothalamus – i thluak peng pakhat – leh i pituitary gland – i thluak bul hnaia awm gland te tak te te hian an thawk dun a, i adrenal glands ten cortisol an siam chhuah chu an thunun a ni. Hei hi a hnathawh dan chu a ni:

• I thisena cortisol level a tlahniam chuan hypothalamus chuan corticotropin-releasing hormone (CRH) tih hormone a tichhuak a.
• Hei hian i pituitary gland chu adrenocorticotropic hormone (ACTH) siam turin a hrilh a ni.
• Tichuan ACTH chu a kal a, i adrenal glands te chu cortisol siam leh chhuah tir turin a hrilh a.

Chuvangin, cortisol level hrisel tak vawng reng tur chuan i hypothalamus, pituitary gland leh adrenal gland te hi a thawk tha vek a ngai a ni.

Eng thilin nge cortisol level sang chhan?

I taksaah cortisol level sang tak i neih rei chuan ( hypercortisolism ), chu chu Cushing’s syndrome an ti tlangpui. Cortisol level sang leh Cushing’s syndrome thlen thei thilte chu:

• Corticosteroid damdawi tam tak ei, prednisone , prednisolone , leh dexamethasone te.
• ACTH- siamtu tumor – Hengte hi i pituitary gland-ah a lo awm tlangpui.
• Adrenal glands-a tumor lo awm leh cortisol tam lutuk siamtu.

Cortisol level sang lutuk hian eng symptoms nge a neih?

Cortisol level a san chuan, chu chu Cushing’s syndrome a ni a, symptoms te chu:

• A bik takin hmai leh pum chhungah taksa rihna a pung.
• A hnungzang ah thau a awm a, a kekawrte inkarah (bawngpa ang maiin).
• A pum chhungah hian stretch mark zau tak, purple rawng a awm tih a lang.
• Kut chunglam leh kekawrte ruh chak lohna.
• Thisen sugar level sang hian Type 2 Diabetes Mellitus a thlen fo thin .
• Thisen sang a sang.
• Hmeichhiaah chuan taksaa sam sei duh loh ( hirsutism ).
• Ruh chak lo ( osteoporosis ) leh ruh tliak a awm thei.

En teh, heng symptom pakhat emaw pahnih emaw i neih vang mai mai hian hlauthawng suh. Mahse heng thil engemaw zat nei nia i hriat chuan doctor pan a tha ber.

Eng thilin nge cortisol level hniam chhan?

Doctor-te chuan adrenal insufficiency an ti a, hei hi cortisol level pangngai aia a hniam chuan ( hypocortisolism ) a awm thin. Hei hi chi hnih a awm a, primary leh secondary.

Primary adrenal insufficiency hi nangmah ngeiin i immune system-in i adrenal glands a beih hian a thleng fo thin. Hei hi Addison natna an ti bawk . Adrenal glands tissue-te a infect emaw, an hnena thisen kal a block emaw chuan cortisol hi a tlahniam thei bawk.

Secondary adrenal insufficiency hi i pituitary gland a thawk tha lo ( hypopituitarism) hian a awm thin.) Ni e, pituitary tumor i neih chuan. Heng dinhmunte hian ACTH siamchhuahna a tikhawtlai a, chu chuan cortisol siamchhuahna a tikhawtlai bawk. Tin, corticosteroid damdawi i hman a, a hnua i chawlhsan nghal chuan i cortisol level a tlahniam thei bawk.

Cortisol level tlahniam hian eng symptoms nge a neih?

Cortisol level a hniam chuan, chu chu adrenal insufficiency , symptoms te chu:

• Chau leh hah lutuk (Fatigue) tih reng reng.
• Tum loh vanga taksa rihna tihtlem.
• Chaw ei chakna hloh.
• Thisen sang hniam.

Engtikah nge ka cortisol level chungchangah doctor ka hmuh ang?

Cushing’s syndrome emaw adrenal insufficiency emaw i vei tih hriat theihna symptom i neih chuan i doctor hmu ngei ang che. Tikhawtlai suh.

Tin, nitin stress chungchanga harsatna i neih chuan i doctor nen inrem dan tur sawipui rawh. Ṭanpuina engemaw tal i dawng thei mai thei.

Engtin nge ka cortisol level hi ka tihhniam theih ang?

Cushing’s syndrome ang chi natna i neih chuan i cortisol level tihhniam nan damdawi lam enkawlna i mamawh ang. Hei hian damdawi emaw, operation emaw a huam tlangpui.

Mahse, a tlangpuiin kan cortisol level control theihna tur kawng engemaw zat a awm a, a bik takin stress avanga cortisol level a san chuan:

• Zan mut hahdam tak nei rawh. Mut theih lohna leh zan lama hnathawh ang chi harsatna te hian cortisol level a tisang thei a ni. Ni khatah darkar 7-8 tal mut tum ang che.
• I taksa tichei la, exercise la. Taksa tihchak fo hian mut a titha a, stress a ti tlem bawk. Ni khatah minute 30 tal kea kal pawh a tha.
• Thâwk thûk tak exercise ti rawh. I thawk dan control tu thawk exercise hian kan parasympathetic nervous system – kan ‘rest and digest’ system a tichak a. Hei hian cortisol level tihhniam nan a pui a ni.
• Hlim rawh, nui rawh. I nuih hian endorphins , happy hormone te chu a chhuak a, cortisol level a tlahniam bawk. Thil hlimawm tak takah tel hian rilru hriselna a tichak bawk.
• Inlaichinna tha leh hrisel tak vawng reng rawh. Buaina leh lungkhamna nei reng inlaichinna hian lungkhamna a thlen fo thin. Chuvangin thian tha leh chhungte nena inlaichinna tha neih reng a pawimawh.

A tawp berah chuan take-home message:

Miten cortisol tih thumal an hriat hian thil tha lo takah an ngai thin. Mahse a takah chuan kan taksa peng hrang hrang tichhe thei hormone pawimawh tak a ni.Stress tihziaawmna tur leh kan cortisol level control theihna tur kawng tam tak a awm. Mahse, a chang chuan cortisol level hi a pangngai lo takin a sang emaw a hniam emaw thei a, chu chu kan thunun theih loh a ni.

Cortisol level sang emaw hniam emaw symptom i neih chuan doctor pan a pawimawh. Test awlsam tlemte an kalpui thei a, chu chuan i adrenal glands emaw pituitary gland emaw hian heng symptoms te hi a thlen em tih an hre thei a ni. I man hma poh leh enkawl a awlsam zawk tih hre reng ang che.

Chuvangin, i taksa hi enkawl la, thil danglam emaw, danglam emaw i hriat chuan damdawi lam thurawn lak hlau suh. Hrisel takin awm rawh!

` Cortisol, stress, hormone, adrenal glands, Cushing’s syndrome, Addison natna