I doctor hian Ibrutinib hi nangmah emaw, i chhungte hnenah emaw a pe tawh em? He damdawi chungchangah hian zawhna tam tak i nei ngei ang, a bik takin liquid (suspension) form-a a awm avangin. "Hei hian eng nge a tih tak tak?", "Eng fimkhur tur nge?", "A side effects a awm em?" Lungngai suh, thil pangngai a ni. Heng zawng zawng hi awlsam tak leh chiang takin sawi ila.
A awlsam zawngin Ibrutinib chu eng nge ni?
Ibrutinib hi targeted therapy drug a ni a, cancer cells te than leh darh dan a control a ni. Thisen leh lymphatic system cancer, leukemia leh lymphoma te enkawlna atan hman a ni ber.
Cancer cell-te hian "insem darh leh pung" turin thuchah (protein) bik an nei tih han ngaihtuah teh. Ibrutinib tih chu chu tirhkoh thiltih chu a block a ni. Tichuan cancer cell te hian an thanlenna tur signal an hloh ta a ni. Chutiang chuan cancer cell darh zau zawng chu a tam zawkin control a ni.
Tin, he damdawi hi bone marrow transplant hnua lo awm thei reaction bik (chronic graft versus host disease) enkawlna atan pawh hman a ni bawk.
He damdawi hi i ei tan hmaa i doctor hnena i hrilh tur thilte
I himna atan he damdawi hi i ei tan hmain i doctor nen zalen taka inbiakna neih a pawimawh hle. A hnuaia mi hi i tan a hman theih chuan i doctor hnenah hrilh ngei ang che.
| I chunga thil awm dan emaw, tih dan emaw chu | Engvângin nge chu chu a pawimawh? |
|---|---|
| Thisen chhuahna lama harsatna emaw, thisen chhuah awlsam duhna emaw | Ibrutinib hian thisen chhuah theihna a tipung thei a ni. |
| Zunthlum | Damdawi hian thisen sugar level a tichhe thei a ni. |
| Tun hnaia operation i neih tawh emaw, nakin lawka tih tum emaw i nih chuan | Operation hma leh operation hnuah damdawi ei hi rei lo te chhung tihtawp a ngai mai thei. |
| Lung natna, thisen sang, a nih loh leh cholesterol sang | He damdawi hian heart rate leh blood pressure a tichhe thei a ni. |
| Liver natna | Damdawi hi liver-in a process a nih avangin a dose pawh tihdanglam a ngai mai thei. |
| Thisen tithianghlim thei damdawi (e.g. Aspirin, Warfarin, Clopidogrel) i ei a nih chuan . | Thisen chhuah theihna hi nasa takin a sang thei a ni. |
| Meizial i zuk chuan | Meizial zuk hian damdawi thenkhat thatna a nghawng a ni. |
| Naupai i nih chuan, nau pai tum i nih chuan, nau hnute i pe a nih chuan | He damdawi hi nausen piang lai tan a tha lo thei a, nu hnute tuiah a kal thei bawk. |
| Damdawi dang, ei tur dang emaw, dye dang emaw allergy i neih chuan | Ibrutinib avanga allergy a awm theih dan tur hre reng ang che. |
Engtin nge damdawi hi ka hman ang?
Hei hi liquid a nih avangin hman dan dik tak hriat a pawimawh hle.
- Doctor-in a tih angin ei rawh: I doctor-in a pek ang zat ei la, nitin hun inangah ei thin ang che. Hun tidanglam lova a ruala ei chuan result tha zawk i hmu thei ang.
- Hman hmain vawt tha rawh: Hei hi tui a nih avangin damdawi chi hrang hrang chu bottle hnuaiah a awm thei. Chuvangin hman hmain bottle chu uluk takin vawt hmasa phawt ang che.
- Measuring device dik hmang rawh: Damdawi nena rawn kal special oral syringe emaw measuring cup emaw chauh hmang ang che. In chhunga teaspoon emaw, soup spoon emaw hmang suh, tehna dik tak a pe lo thei a ni.
- Dose hi duh duhin thlak suh:Side effect i neih chuan i doctor chuan i dose a tihhniam thei a, hun engemaw chen chu damdawi ei a chawlhsan thei bawk. Mahse i doctor thurawn tel lo chuan damdawi ei kha bansan ngai suh la, a dose pawh thlak ngai suh.
Pawimawh tak: He damdawi ei lai hian grapefruit ei loh tur leh grapefruit tui in loh tur a ni. Tin, Seville orange pawh ei suh. Heng thei te hian i taksaa damdawi hnathawh dan a tibuai thei a ni.
Damdawi dose i ei loh chuan engtin nge i tih ang?
Dose i ei theihnghilh chuan i hriatreng veleh ei nghal rawh. Mahse, i dose leh tur hun a lo thleng tawh a nih chuan (e.g., darkar tlemte chauh a la awm) a nih chuan, i dose loh chu skip la, i dose leh tur chu a hun ruatah ei rawh. Dose hloh tawh chu tihpun nan double dose ei suh.
Damdawi ka ei tam lutuk chuan engtin nge ni ang?
Damdawi i ei tam lutuk nia i inhriat chuan hlauthawng suh. Colombo National Hospital-a National Poisons Information Center-ah phone nghal rawh. A nih loh leh damdawi in hnai ber Emergency Treatment Unit (ETU)-ah kal rawh.
He damdawi nena inzawm thei thil dang
I damdawi ei zawng zawng, natna dang damdawi te, vitamin te, hnam damdawi te, leh thinghnah te pawh i doctor hnenah hrilh vek a pawimawh hle . Chutianga tih loh chuan side effect hlauhawm tak a thlen thei a ni.
Ibrutinib hian damdawi dang nen a inzawm thei a ni. A bik takin a hnuaia damdawi te hi fimkhur rawh:
- Antibiotics leh antifungal thenkhat
- HIV emaw hepatitis emaw damdawi thenkhat
- Cancer dona damdawi dang
- Seizures damdawi thenkhat
- Thlai chi hrang hrang, St. John’s Wort ang chi te
Hei hi list kimchang a nih loh avangin i ei zawng zawng doctor hnenah hrilh vek a him ber.
Damdawi ei huna fimkhur tur thil
- Damdawi lam enfiah fo: I doctor-in a hmuh fo a ngai dawn a ni. Damdawi hian i taksa a nghawng dan enfiah turin thisen test mumal tak neih a ti bawk ang. Hengte hi skip suh.
- Thisen chhuah chungchangah fimkhur rawh: He damdawi hian thisen chhuah theihna a tipung thei a ni. I hliam awlsam thei a, a nih loh leh hliam tenau tak pawhin thisen chhuah tihtawp nan hun rei tak a la ngai thei bawk. Thisen chhuak danglam (e.g., hmui thisen chhuak, hnar thisen chhuak) i hmuh chuan doctor hnenah hrilh rawh.
- Infection lakah fimkhur rawh: I immune system a chak lo deuh thei. Chuvangin natna hrik i kai tam zawk. Khawsik, taksa na, khuh, hnar luang ang chi symptoms i neih chuan mahni indam lo la, doctor hnenah hrilh rawh. Mipui tamna hmun leh damlo awmna hmunte chu a theih ang anga pumpelh tur a ni.
- Ha enkawlna: Ha enkawlna emaw, operation emaw i neih dawn chuan Ibrutinib i ei thu i ha enkawltu hnenah hrilh ngei ang che. He damdawi ei lai hian ha surgery lian tham tih loh a tha ber.
- Naupai leh nau hnute pek: Hei hi a pawimawh hle. He damdawi hi i ei lai leh i chawlh hnu thla khat chhung chu naupai loh tur a ni. Tin, he damdawi hi i ei lai leh i chawlhsan hnu kar khat chhung chu nau hnute pe suh. Hemi chungchanga zawhna i neih chuan doctor nen inbia ang che.
Damdawi avanga side effect lo awm thei
Damdawi dang ang bawkin he damdawi hian side effect a nei thei a ni. Ṭhenkhat chu hlauhawm tak an ni a, ṭhenkhat chu mi pangngai an ni.
| Side effect na tak tak, doctor hnena hriattir nghal tur | |
|---|---|
| Allergy natna a awm thei | Vun vun rawng, hnim hring, hmai, hmui emaw lei emaw a hring, thawk harsa. |
| Thisen chhuak | Black or tarry stools, coffee grounds ang maia luak chhuak, zun sen/dark brown, taksaah hliam danglam tak emaw, sen/purple te te. |
| Lung lam harsatna a awm | Thâwk harsa, ke ruh leh ke ruh hring, rang taka taksa rihna sang, hahna danglam tak, thinlung thawk chak emaw, mumal lo emaw, rilru na. |
| Kaichhawng | Khawsik, khawsik, khuh, ril na, hliam dam lo. |
| Tumor Lysis Syndrome (TLS) natna a awm thei lo. | Luak chhuak, luak chhuak, luak chhuak, zun chhuah tlem, taksa ruh thawm, ruh na. |
| Side effects hlauhawm lo tlangpui, mahse a awm reng chuan doctor hnenah hriattir tur a ni | |
| Kawthalo | Pum natna |
| Chau | Chauhna leh hah lutuk tih hriatna. |
| Na | Lu na, thau na, ruh na, pum na. |
| Luhai | Luak chhuak ang maia hriatna. |
Engtin nge damdawi chu i dahkhawm leh i paih thin?
- A dahna: Naupang leh ran vulhte hmuh theih lohna hmunah room temperature (20-25 degree Celsius inkar)-ah dah tur a ni. Damdawi chu a original bottle-ah dah fo ang che.
- Hman dan: Damdawi la awm zawng zawng chu bottle hawn atanga ni 60 chhungin paih vek tur a ni. Damdawi hman hun tawp tawh emaw, duh loh emaw paih dan tha ber chu i damdawi in emaw, damdawi dawr emaw-a damdawi lak let lehna program-a hruai hi a ni. Chutiang a nih loh chuan damdawi tui chu bag-ah dah la, coffee ground hman tawh, lei emaw, ui bawlhhlawh ang chi thil nen chawhpawlh la, bag chu khauh takin seal la, bawlhhlawh bawmah paih rawh. Toilet chhungah hian flush ngai suh.
Take-Home Thuchah a ni
- Ibrutinib hi cancer enkawlna atana damdawi pawimawh tak a ni. Doctor-in a sawi angin a dose dik tak ei tur a ni.
- Damdawi dang i ei zawng zawng, vitamin pawh nise, i doctor hnenah hrilh rawh.
- Damdawi ei lai hian grapefruit leh Seville orange te hi pumpelh vek tur a ni.
- Thisen chhuahna danglam tak, khawsik emaw, natna hrik kai theihna chhinchhiahna emaw a awm chuan fimkhur rawh. Chutiang thil i hriat chuan doctor hnenah hrilh nghal rawh. (Ngawi teh, chu chu Tamil/Malayalam a ni. I siam that ang u.) Chutiang thil i hriat chuan i doctor hnenah hrilh nghal rawh.
- Damdawi ei lai leh hun bituk chhung atan naupai leh nau hnute pek loh tur.
- Zawhna emaw rinhlelhna emaw i neih chuan i doctor nen pawh sawipui ngei ang che. Hlau suh la, mahni thuin thutlukna siam suh.
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