Nausen dam tirh lamah hian hmeichhiate tana thil danglam bik, uterus, fallopian tube leh cervix te hi engtin nge an lo thanglian tih i ngaihtuah ngai em? Thil mak leh buaithlak tak a ni tak zet a ni. A bul tanna chu embryonic stage-a lo awm tube te tak te pahnih, nalh tak tak pahnih atanga tan a ni. Damdawi lamah chuan hengte hi ‘Müllerian ducts’ kan ti a. He hming hi i la hre ngai lo mai thei. Mahse hmeichhe reproductive health chungchang sawi dawn chuan he system of tubes hi hriat a pawimawh hle. Chuvangin vawiinah hian awlsam tak leh i hriatthiam theih tur angin i sawi dawn nia.
A awlsam zawngin, heng Müllerian Ducts te hi eng nge ni?
Müllerian ducts hi tube pahnih pahnih inzawmkhawm a ni a, nausen chu nu pum chhunga a lo thanglian zel angin a lo piang a ni. Heng duct te hi paramesonephric duct an ti bawk. Mahse, Müllerian ducts tih hming hi hman a ni ber.
An hna ber chu hmeichhe nau neihna atana taksa peng lian ber ber siam hi a ni. A bik takin, heng tube pahnih hi a hnua heng taksa peng hrang hranga lo piang chhuakte hi an ni:
- Uterus: Naute thla 9 chhung phurtu leh chawmtu taksa peng mak tak a ni.
- Fallopian tubes: Ovary atanga uterus thlenga egg phurtu tube pahnih.
- Cervix: Nausen pum hnuai lam, vagina nena inzawm.
- Vagina chunglam section.
Ngaihtuah teh, heng tube te tak te pahnih hi nakin lawka nu nih leh fa neih theihna tura taksa peng pawimawh tak takah a lo thang lian a ni.
Mak tak mai chu heng Müllerian ducts te hi embryo zawng zawngah, mipa leh hmeichhia thliar lovin, an lo pian tirh lamah an awm vek a ni. Chuti a nih chuan engtin nge naute mipa hian nausen pum a siam lo va, naute hmeichhia chauh a neih theih?
A chhan chu sexual differentiation, sex organs lo thanglian dan a ni. Nausen mipaah chuan hormone bik anti-Müllerian hormone (AMH) an tih chu a chhuak a. He hormone hian Müllerian ducts te hmasawnna a titawp a, zawi zawiin a atrophie thin. Chuvang chuan nausen mipa chuan nausen pum angin taksa peng hrang hrang a nei lo.
Mahse, nausen hmeichhiaah chuan he AMH hormone hi a awm lo. Chuvangin, Müllerian ducts te hi daltu awm lovin an lo thang lian a, a hmaa kan sawi tawh hmeichhe chi thlahtu (reproductive organs) te hi a lo piang ta a ni.
Chuti a nih chuan Wolffian Ducts hi eng nge ni? An pahnih inthlauhna chu eng nge ni?
Müllerian ducts te nen hian embryo hmasa apianga awm duct system dang chu Wolffian ducts hi a ni. Chungte chu mesonephric ducts an ti bawk. Heng duct pahnih hnathawh dan hi a danglam vek a ni. Hei hi chiang taka hrethiam tur chuan a hnuaia table hi en la.
| Hnamhnawih | Müllerian Duct-te chu a awm a | Wolffian Duct-ah chuan a awm a |
|---|---|---|
| Hnathawh ber | Hmeichhe reproductive system-a taksa peng hrang hranga lo thanglian. | Mipa reproductive system-a taksa peng hrang hranga lo thanglian. |
| Hmeichhe nausen (fetus) ah chuan | A thang tha a, nausen pum, fallopian tubes, etc. a siam thin. | Zawi zawiin a chhe a, thil chi hrang hrang pawimawh lo tak tak a hnutchhiah thin. |
| Mipa nausen (fetus) ah chuan | Anti-Müllerian Hormone (AMH) hian thanlenna a titawp a, a tichhe thei bawk. | Hormone testosterone nghawng hnuaiah a thang tha hle. |
| Organ lo piang chhuak leh lo piang chhuak | Uterus, fallopian tubes, cervix, serh chunglam. | Vas deferens, epididymis, seminal vesicles te an ni. |
A awlsam zawngin, heng vascular system pahnih hi embryo khatah awm mah se, hormone-te nghawng hnuaiah pakhat chu a lo thang lian a, pakhat chu a atrophie thung. Hei hi thilsiam inthlauhna mak tak chu a ni.
Engtin nge heng tube te hi an lo thanglian a, khawiah nge an awm?
Hetiang kalphung hi naupai lai atanga tan a ni. Naute chu a pian atanga kar 3-4 hnuah a pum chhungah nau pai a ni.He thawnthu hi nau pai lai vel atanga intan a ni. Chutih lai chuan heng Müllerian ducts te hi embryo chhunga kal hmasa ber (mesonephric kidneys) bulah an lo piang tan ta a ni. Heng kal hmasa berte hi hun eng emaw chen atan a ni a, kal nghet (permanent kidney) hi a hnuah a lo piang chhuak thin.
Heng duct te hi kut zungtang ang maia sei tak tak projection angin hnuai lam hawiin an thang lian thin. Naupai kar 8 leh kar 12 inkarah chuan Müllerian duct hnuai lam pahnih tip te chu an fuse khawm thin. He fusion hian uterus leh vagina ang chi organ te dinna bulpui a siam a ni. Heng duct te hi cell chi hrang hrang pahnih atanga siam an ni.
- Epithelial cells: Hengte hi kan taksa peng hrang hrangte venna khuhna ang mai an ni a, thil pawimawh tak takte hip lut leh chhuah tir turin an pui bawk.
- Mesenchymal cells: Hei hi stem cell chi khat a ni. Chumi awmzia chu heng cell te hi a tul angin cell chi hrang hrangah an lo thang lian thei tihna a ni.
Müllerian duct anomalies a awm thei em?
Ni e, a châng chuan heng Müllerian duct te hi an lo thang tha lo emaw, an inzawm khawm lo emaw a, chu chuan chhiatna leh thil danglam chi hrang hrang a thlen thin. Hengte hi pianpui natna a ni fo thin .
A pawimawh ber chu puitling i nih hma emaw, nupui pasal nei tawh leh fa i beisei hma loh chuan he natna hi i nei tih i hre lo mai thei. A chhan chu pawn lam chhinchhiahna a awm lo mai thei. Hmeichhe thenkhat chuan nau pai theih lohna chhan an zawn lai chauhvin he natna hi an nei tih an hmuchhuak thin.
A hnuaia table-ah hian Müllerian duct defect awm fo thin thenkhat tarlan a ni.
| Anomaly hming | Eng thil nge thleng mai mai? |
|---|---|
| Müllerian agenesis emaw hypoplasia emaw a awm thei | Uterus hi pian tirh atangin a awm lo (agenesis) emaw, a te hle a, a lo thanglian lo (hypoplasia) . Hei hi entirnan a langsar ber chu genetic condition Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome hi a ni. |
| Vaginal septum (vagina chhunga membrane awm) . | Tube pahnih hi a hnuai lama an inzawm laiin an inzawm tha lo a nih chuan vagina sir zawng zawngah membrane a lo awm thin. Hei hian vagina chu a then emaw, a pumin emaw a block thei a, a nih loh leh vagina pahnih a siam thei bawk. |
| Müllerian duct syndrome (PMDS) natna hrik awm reng chu a awm lo. | Hei hi genetic condition hmuh tur awm lo tak a ni a, mipa naupangte pawh a nghawng nasa hle. AMH hormone hian hna a thawk tha lo a, a uterus leh fallopian tubes te hi mipa reproductive organ pangngai nen an lo piang chhuak thin. Heng mipa te hian harsatna an nei thei bawk a, chu chu undescended testicles te hi a ni. |
| Nausen pum (uterine) a dik lo | Tubal hmasawnna lama harsatna a awm chuan nausen pum hi a pianzia a tidanglam thei a ni. Entirnan, bicornuate uterus, didelphys uterus, septate uterus leh T-shaped uterus te hi a ni. |
Hetiang chhiatna nei thenkhatte hian an kal (kidney) lamah harsatna an nei thei bawk. Hei hi a chhan chu nausen lai hian heng taksa peng pahnih hi an inhnaih hle a, pakhata chhiatna a awm chuan a dang a nghawng thei a ni.
Heng tihsual chi hrang hrang hi a awm fo em?
Ni lo, he thil hi i ngaihtuah buai a ngai lo. Hengte hi dinhmun a tlem hle. Statistics atanga a lan dan chuan he chhiatna chi hi nau piang nung zinga za zela tlemteah a awm a, 0.1% leh 3.0% inkar a ni. Chumi awmzia chu hetiang thil thleng theihna chance hi a tlem hle tihna a ni.
Doctor hnenah eng zawhna nge i zawh tur?
Doctor-in nangmah emaw i fa emaw chu Müllerian duct defect i nei tih a hriat chuan i rilruah zawhna tam tak awm hi thil pangngai a ni. Chutih lai chuan engmah tikhawlo lovin i doctor hnenah heng zawhnate hi zawt rawh.
- Hetiang dinhmun hian ka nau neih theihna (nau neih theihna) a nghawng dawn em ni?
- Hei hian ka hormone a nghawng dawn em ni?
- Hei hi eng enkawlna nge ni? Surgery neih a ngai em?
- Ka puitlin hun leh ka thlasik hun hi a pangngaiin a thleng dawn em ni?
I doctor chuan heng zawhna zawng zawng hi chhanna chiang tak a pe ang che a, i mamawh kaihhruaina pawh a pe ang che.
Naupai lai hian heng tihsual chi hrang hrangte hi ven theih a ni em?
Hei hi mi tam takin harsatna an neih a ni. Dik tak chuan Müllerian duct defects hi pumpelh vek theih a ni lo.A chhan chu hengte hi genetic cause emaw, nausen pian laia random error emaw avanga lo awm a ni fo thin.
Mahse, chu chuan kan tih theih a awm lo tihna erawh a ni lo. Nu naupai i nih angin, a tlangpuiin nau piangsual i neih theihna tur tihtlem nan nun hrisel i zawm thei a ni. Hei hi heng chhiatna chi hrang hrang tan chauh ni lovin, i naute hriselna zawng zawng atan a pawimawh hle.
- Dan loa ruihhlo leh marijuana hman loh vek tur a ni.
- Meizial leh zu in loh vek tur a ni. Hengte hi nausen tan chuan a pawi hle.
- Naupai lai hian damdawi lam thurawn leh nau neih hmaa enkawlna dik tak dawng ngei ngei tur a ni.
- Natna khirh tak tak, zunthlum emaw, thisen sang emaw i neih chuan naupai hmain uluk takin control thin ang che.
- Nau neih hmaa vitamin folic acid awmna hi doctor-in a rawt ang chiah hian ei thin ang che.
- I taksa rihna hrisel tak vawng reng rawh.
- Diet inthlau tak ei la, nitin exercise engemaw zat nei bawk ang che.
Heng thil awlsam tak tak hmang hian i nausen piang tur chu hrisel taka a thanlen theih nan boruak tha ber i siam thei a ni.
Take-Home Thuchah a ni
- Müllerian ducts hi embryonic stage-a lo awm duct system a ni a, hmeichhe chi thlahtu, uterus leh fallopian tube te lo thanglian zelna atana pawimawh tak a ni.
- Heng hmasawnna lama harsatnate hi pian tirh lamah a awm a, puitling emaw, fa beisei hun emaw thlengin hriat theih a ni lo thei.
- Heng tlin lohna te hi a tlem hle a, a tam zawk chuan enkawl dan leh enkawl dan an nei a ni.
- Hemi chungchangah hian ngaihtuahna emaw rinhlelhna emaw i neih chuan i doctor nen zalen taka inbiakna neih a pawimawh hle a, thurawn dik tak i lak a pawimawh hle.
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