Neuroendocrine Tumors chungchang hi a awlsam zawngin i zir ang u.

I chau fo em, i pum na i nei fo em, a nih loh leh sawifiah theih loh khawpa hrehawm i nei fo em? Heng thilte hi thil pangngai angin kan hnawl fo thin. Mahse, a châng chuan, heng chhinchhiahna tenau tak takte hnung lamah hian, kan hriat reng tûr dinhmun, mahse pawimawh tak a awm thei a ni. Chutiang dinhmun pakhat, a awm lo zawk mahse pawimawh tak chu neuroendocrine tumors a ni a, a nih loh leh English-a kan sawi angin, `Neuroendocrine Tumors (NETs)` tih hi a ni.

Heng neuroendocrine tumor (NET) te hi engte nge ni?

A awlsam zawngin sawi ila, hei hi kan taksaah hian tumor chi khat, a awm lo hle. Chungte chu kan ‘neuroendocrine cells’ atanga tan a ni. Tunah chuan hengte hi eng ang cell nge an nih tih i ngaihtuah mai thei. Thil mak tak chu heng cell te hian nerve cells property leh endocrine cells property te hi an nei vek a, chu chuan hormone a siam chhuak a ni. Chumi awmzia chu heng cell te hian nervous system atanga thuchah an dawng thei a, chu chu a chhanna atan thisenah hormone an chhuah tir thei tihna a ni.

Heng neuroendocrine cells te hi kan taksa hmun tam takah kan awm a. Lung, pum, pancreas, leh intestines ang hmunah te an awm tam ber. Chuvangin, eng emaw chhan vanga heng cell te hi thunun theih loha an inthen a, an pung chhoh tan chuan tumor a lo awm ta a ni. Heng tumor tam tak hi malignant an ni a, cancer an ni thei tihna a ni.

Heng tumor te hi an danglam hle a ni. Ṭhenkhat chu an ṭhang zawi hle a, ṭhenkhat erawh chu an ṭhang chak hle thung. Tin, an natna lan chhuah dan leh enkawl dan pawh hi tumor awmna hmun leh a nihna azirin a inang lo hle bawk.

Heng nut chi hrang hrang hi engte nge ni?

Doctor-te chuan heng tumor te hi kawng hnih in an thliar hrang a. Pakhat chu hormone an siam chhuah leh siam lohah a innghat a ni.

• Functional NETs: Heng NET chi hrang hrangte hian hormone an siam chhuak thin. Chuvangin, taksaah hormone sawi tur a lo pun chuan heng mite hian natna lan chhuah dan chu a rawn lang nghal mai thei a, chu chu rang taka luang chhuak, thawk hah, leh puak chhuak te hi a ni.
• Non-functional NETs: Heng NET chi hrang hrangte hian hormone an siam chhuak lo. Chuvangin, a tir lamah chuan symptoms an nei lo mai thei. NETs te hi an lo thanglian a, an awmna organ-ah pressure a siam emaw, a hnathawh a tibuai emaw chauhvin symptoms a lang thin.

Tin, heng tumor te hi taksaa an awmna hmun azirin an thliar hrang bawk. Heng chi hrang hrangte hi a tam ber a ni.

Heng hmunpui pathum bakah hian heng tumor te hi thyroid gland, parathyroid glands, pituitary gland, leh adrenal glands ang hmunah te pawh a lo awm tlem hle bawk.

He natna hi engtiang chiahin nge a hluar?

Khawvel pumah he natna hian mi 100,000 zinga 6 vel a vei a ni . Chumi awmzia chu natna hmuh tur awm lo tak a ni tihna a ni. Amaherawhchu, tun hnaiah he natna vei hmuhchhuah zat hi a pung ve deuh a ni. Hei hi tunah chuan advanced diagnostic test hmanga heng tumor te hi a hma leh awlsam zawka hmuhchhuah theih a nih vang pawh a ni thei.

He natna hian kum eng pawh a nghawng thei a, mahse naupang leh puitling tleirawl zingah a tlem hle. Kum 50 leh 60 inkar ah a tam ber .

He natna lan chhuah dan engte nge ni?

Hei hi harsatna lian ber a ni. Vawi tam tak chu heng tumor te hian a bul hnaia taksa peng hrang hrangte nghawng thei tur khawpa lian an nih hma chuan engmah chhinchhiahna an nei lo. Symptoms a awm tak tak pawhin tumor awmna hmun azirin a danglam thei. Tin, heng chhinchhiahnate hi natna tlanglawn dangte nen a inang em em a, awlsam takin natna dang anga ngaih theih a ni bawk.

Heng natna lan chhuah dan tlangpui thenkhat chu hetiang hi a ni:

• Chau
• Pum a na
• Kawthalo
• Nausea leh luak chhuak
• Thâwk harsa
• Khuh (a chang chuan thisen nen) .

Engvangin nge heng tumor te hi an lo awm? Risk factors te chu engte nge ni?

Doctor-te chuan engvangin nge heng neuroendocrine cells te hi thunun theih lohvin an inthen darh nghal tih chiang takin an la hre lo. Chumi awmzia chu a chhan dik tak an la hre lo tihna a ni.

Mahse, mi thenkhat, rare, inherited genetic conditions (syndromes) nei te chu heng tumor te hi an vei theihna a sang zawk tih hmuhchhuah a ni. Chumi awmzia chu he natna hi gene thenkhat inthlak danglamna (mutations) vang a ni thei tihna a ni.

• Multiple Endocrine Neoplasia (MEN): He natna hian gland leh taksa peng hrang hrangah tumor a siam thin. MEN type 1 (MEN1) tia koh he natna vei te hi pancreatic tumor (P-NETs) vei an hlauhawm hle.
• Von Hippel-Lindau syndrome: Hetiang natna hian taksa peng hrang hranga cancer leh common tumor neih theihna a tipung a ni.
• Neurofibromatosis type 1: Hetiang dinhmunah hian vun leh nerve-ah tumor a lo awm thin.
• Tuberous sclerosis complex: Hei hian taksa khawi hmunah pawh tumor a siam thei a, a bik takin thluak chhungah hian tumor a siam thei a ni.
• Cowden syndrome: He natna hian tumor leh cancer chi thenkhat a vei theihna a tipung bawk.

Engtin nge natna hi kan hriat theih ang? (Diagnosis) tih a ni.

Kan sawi tawh ang khan he natna lan chhuah dan hi a tlangpui em em a, a hriat theih nan hun rei tak a ngai thei. I doctor-in a rinhlelh chuan tumor awmna hmun nia an ngaih dan azirin test hrang hrang an ti ang.

Tumor hi eng stage leh grade nge ni?

He natna hi i vei tih finfiah a nih veleh doctor chuan a stage leh grade a sawipui ang.

• Stage: Hei hian cancer a darh tawhna a kawk a ni. Stage 1 atanga 4 thlenga grade a ni tlangpui a, a tlem chuan tumor a te zawk a, a darh tlem zawk bawk. Stage 4 hian cancer chu taksa hmun hla tak takah a darh (metastatic) tihna a ni tlangpui.
• Grade: Hei hian microscope hmanga cell awm dan pangngai lo leh an inthen chak dan a kawk a ni. Grade 1 leh 2 (Well-differentiated) tumor te hi an thang zawi zawi a, grade 3 (Poorly differentiated) tumor te erawh an thang chak hle thung.

He stage leh grade hian i dinhmun a nghawng dan hriat tumin i doctor nen inbia ang che.

Enkawlnate chu engte nge ni?

Enkawl dan hi thil tam takah a innghat a, chu chu i tumor chi hrang hrang, a lian leh te, a darh leh darh loh leh i hriselna zawng zawng a ni.

Chumi atana enkawlna ber leh hman tlanglawn ber chu surgery a ni. Surgery hmanga tumor hi lakchhuah vek theih a nih chuan a dam theihna chance a sang hle.

Mahse, tumor te hi a lian emaw, hmun dangah a darh tawh emaw a nih chuan enkawl dan dang a ngai mai thei.

• Somatostatin analogs: Hei hi damdawi chi khat a ni a, taksain hormone a siam tam lutuk loh nan a titawp a ni. Symptoms tihziaawmna leh tumor thanna control thei an ni.
• Chemotherapy hmanga enkawlna:Damdawi chak tak, cancer cell thattu.
• Targeted therapy: Heng damdawi te hian cancer cell-a awm chauh gene emaw protein emaw bikte chu an target a, an bei a, chu chuan cell hriselte a tichhe tlem hle.
• Radiation therapy: Hei atan hian radiation treatment bik hman a ni. Entirnan, `peptide receptor radionuclide therapy (PRRT)` tih dan chuan radioactive substance hmangin hormone siamtu tumor te chu target-in a tichhia a ni.

He natna hi engtin nge kan nunpui ang?

NET i neih i hriat chuan zawhna tam tak i nei mai thei. Hei hi tihdam theih a ni em? Ka hmalam hun chu eng ang nge ni ang?

He natna lo thleng tur hi thil engemaw zat ah a innghat a ni. Chung zingah chuan tumor chi hrang hrang, a darh tawh em tih te, enkawlna a dawn dan a tha em tih te pawh a tel. A vaiin, natna hmuhchhuah hnu kum nga chhunga damchhuah zat chu 39% vel a ni.

Treatment zawh hian engkim a tawp tihna a ni lo. Heng tumor te hi an thang chak hle a, enkawl hnuah pawh a lo lang leh thei a, chuvang chuan i doctor chuan kum tam tak chhung a lo enkawl ang che.

Engtin nge i in enkawl theih ang?

He natna leh a enkawl dan hian i taksa leh rilruah nghawng thui tak a nei thei a ni.

• Support group-ah tel ve rawh: Cancer dona ringawt pawh hi a harsa hle. A bik takin hetiang natna hlauhawm tak i neih hian i hrehawmna hrethiamtu hmuh a harsa thei hle. Hetiang natna vei te tanpuitu pawl chungchang hi i medical team hnenah zawt rawh.
• Chaw tha ei rawh: Enkawlna avanga nghawng tha lo a awm chuan ei duhna a hloh thei. I chakna level vawng reng thei tur ei tur chungchanga thurawn dietitian zawt rawh.
• Rilru lama tanpuina dawng rawh: He zinkawng hi i ngaihtuah angin a awlsam lo. Emotionally overwhelmed i nih chuan mental health professional hnen atanga tanpuina dil zak suh.
• Zu in chungchangah fimkhur rawh: Zu in hian symptom thenkhat a tizual thei a, chuvangin zu in chungchangah doctor rawn la.

Engtikah nge Doctor ka hmuh ang?

NET i nei a nih chuan i taksaa inthlak danglamna awm thei chu fimkhur hle ang che. A bîk takin, i rilru a luang chhuak nghal a, i pum a zau a, i thawk hah a nih chuan, chûngte chu carcinoid syndrome an tih natna chhinchhiahna a ni thei. Chutiang hunah chuan doctor hnenah hriattir nghal tur a ni.

Tin, i natna lan chhuah dan a zual a nih chuan, emaw, enkawlna avanga nghawng tha lo a awm chuan tuar harsa a nih chuan, doctor thurawn zawng rawh.

Engtikah nge Emergency Treatment Unit (ETU) ah i kal ang?

NET hian thinlung a nghawng thei tih a awm bawk. I ke emaw, ke ruh emaw-ah thil danglam tak a hring chhuak a, thawk harsa i tih thut chuan damdawi in hnai ber Emergency Department (ETU)-ah kal nghal rawh.

A tawp berah chuan hetiang natna hlauhawm tak i hriat hian zawhna tam tak neih hi thil pangngai a ni. I doctor nen zalen taka inbiakna leh zawhna zawng zawng zawh hian i hriselna thunun theihna kawngah kawng thui tak a zawh thei a ni.