I damlo fo em? IgA Deficiency vang pawh a ni thei.

Khawsik, khuh, leh ril na i nei fo em? A nih loh leh, natna tenau nei i hnaih ber aṭangin awlsam takin i man em? Mi thenkhat chu midang aiin an damlo tam zawk. An "nature" mai mai niin kan ngai. Mahse chutiang chu a ni reng reng lo. Chutianga kan tih chhan pakhat chu kan taksa invenna (defence system), chu chu immune system-a chak lohna tlem vang a ni thei. Vawiin hian IgA Deficiency chungchang kan sawi dawn a, chu chu mi tam takin an hriat loh, natna tlanglawn tak a ni.

A awlsam zawngin IgA tlakchhamna hi eng nge ni?

Kan taksa hian mahni invenna sipai a nei a, ram ang maiin. Hei hi Immune System kan ti a . He system hnathawh ber chu pawn lam atanga taksaa lut virus leh bacteria te hriatchhuah leh tihchhiat a ni a, natna laka min humhim hi a ni.

He security force-ah hian sipai chi hrang hrang an awm a. Chutiang sipai bik pakhat chu Immunoglobulin an ti a . Hengte hi a takah chuan kan taksa siam protein chi khat an ni. Heng immunoglobulin te hi chi hrang hrang a awm a. A, G, M, E, D te ang bawkin.

Tuna kan sawi IgA hi immunoglobulin A chi khat a ni a, he IgA hian thil danglam bik a nei a. Kan taksa chhunga mucous membrane-ah a awm ber a ni. Chu chu:

• Mit
• Beng
• Kawng leh kawr
• Thâwk chhuahna kawng (respiratory system) .
• Chaw ei dan (intestine) .

Hengte hi kan taksaah awlsam taka natna hrik a luh theihna hmun a ni. Chuvangin he guard IgA tia koh hian heng kawngkaah hian guard-in a thu a, natna hrik lut tur a veng a ni.

IgA tlakchhamna hian mi taksain he invenna protein IgA an tih hi a siam chhuak tawk lo tihna a ni. Mi thenkhat chuan an siam chhuak tlem hle. Mi dangte chuan an siam chhuak lo mai thei.

Mahse a tha ber chu a tam zawkah chuan kan immune system-a sipai dangte (IgG leh IgM ang chi) te hian he tlakchhamna hi eng emaw chen chu phuhruk an tum thin. Chuvangin IgA tlakchhamna nei tam zawk chuan an dam chhungin symptom emaw complication emaw an nei lo. Hetiang dinhmun hi an nei tih pawh an hre lo.

IgA tlakchhamna chhinchhiahnate chu engte nge ni?

Kan sawi tawh ang khan mi tam zawk hian symptom an nei lo. Mahse, mi thenkhat chuan symptom thenkhat an nei thei. Chung zinga pawimawh ber chu midang aiin hri kai tam zawk hi a ni.

Nimali tih hming pu mi pakhat han ngaihtuah teh. A office-a mi pakhatin khawsik a neih chuan Nimali chu a tuar leh tur a ni. Midangte chu ni hnih emaw ni thum emaw chhungin an dam laiin Nimali erawh kar khat vel a ngai thung. A châng chuan sinusitis-ah a kal chho ṭhin. Hei hi IgA tlakchhamna neiin a tawn thin chu a ni.

Hetiang dinhmun avang hian eng harsatna nge lo awm tlangpui tih hriat tumin a hnuaia table hi han en ila.

Engvangin nge hetiang dinhmun hi a lo awm?

IgA tlakchhamna chhan ber chu genetic a ni . Chumi awmzia chu he natna nena inzawm genetic changes hi nu leh pa atanga fate hnena rochun a ni tihna a ni. I chhungkuaa mi tu emaw, a bik takin i nu leh pate pawhin he natna hi an vei a nih chuan, i vei theihna chu midang aiin a let 50 velin a sang zawk a ni.

A tlem hle a, IgA level hniam pawh hi damdawi thenkhat hun rei tak hman avanga side effect a ni thei bawk. Entir nan:

• Immunosuppressant hmanga taksa hriselna tichhe thei
• Epileptic damdawi thenkhat (e.g. Phenytoin) .
• Ruh natna damdawi thenkhat (e.g. Penicillamine, Sulfasalazine) .

He natna hian eng harsatna leh nghawng dangte nge a neih?

Hetah pawh hian mi tam zawk chuan harsatna an tawk lo. Buaina lo awm thei ber chu natna fo tawh hi a ni.

Mahse, IgA tlakchhamna nei te hi mipui zawng zawng aiin autoimmune natna vei theihna chance a sang deuh thei a ni.

Heng autoimmune natna te hi engte nge ni?

A awlsam zawngin, hei hi kan taksa immune system a chhiat lai a ni. Chu chu hnam dang natna hrik a beih ai chuan kan cell leh tissue hrisel tak takte chu a bei tan tihna a ni. Hei hian natna chi hrang hrang a thlen thin.

IgA tlakchhamna nena inzawm thei natna thenkhat chu:

• Rheumatoid Arthritis: Natna a ni a, ruh ruh a ti na a, a na bawk.
• Lupus: Taksa peng hrang hrang khawih thei dinhmun a ni.
• Celiac Disease: Taksain gluten (wheat flour-a protein awm) a tihbuai dan a ni.

IgA tlakchhamna hian hahna a thlen em?

Hei hi mi tam takin an zawh thin a ni. IgA tlakchhamna ngei pawh hian direct-in hahna a thlen lo. Mahse, a hmaa kan sawi tawh autoimmune natna pakhat i neih ve bawk chuan chu natna chhinchhiahna angin hahna nasa tak i tawk thei a ni. Chuvangin sawifiah theih loh khawpa hahna i neih chuan i doctor nena inbiakna neih a pawimawh hle.

Engtin nge doctor hian hei hi a hriat chian? Eng nge a enkawl dan?

Diagnosis tih a ni

IgA tlakchhamna hriatchhuah hi a awlsam hle. Thisen test chauh a ngai a ni . He test hian i thisena immunoglobulin hrang hrang awm zat a teh thin. I IgA level a hniam lutuk emaw, a awm loh emaw chuan i doctor chuan i natna chu a nemnghet thei ang.

A tam zawkah chuan hei hi thil thleng mai maia hmuhchhuah a ni. IgA level hniam hi thisen test a nih chauhvin natna dang a awm leh awm loh hmuhchhuah a ni. I chhungkuaa tu emaw hian he natna hi a nei tih i hriat chuan i doctor hnenah hrilh a pawimawh.

Tihdamna

Heta hriatthiam tur pawimawh tak chu IgA tlakchhamna hi kan taksaa genetic mutation avanga lo awm a nih avangin enkawlna leh damdawi bik a awm lo tih hi a ni.

Chuti a nih chuan doctor hian eng nge a tih? IgA tlakchhamna hi a enkawl lo va, a natna lan chhuah dan leh natna hrik awmte a enkawl zawk a ni.

• Bacteria infection i neih chuan antibiotics pek i ni ang .
• Infection i neih fo leh na tak i neih chuan a chang chuan saline hmangin immunoglobulin pek i ni thei a, chu chuan i immune system a tichak thei a ni.IVIG infusion hi a tha mai thei a, mahse hei hi tih a tlem hle.
• Asthma, allergy, autoimmune disease i neih chuan enkawlna \ha tak pek i ni ang.

Naupang thenkhat tan chuan an upat deuh deuh chuan IgA level chu a pangngaiin a lo let leh thei a, mahse hei hi mi zawng zawng tan chuan a ni lo.

Engtikah nge Doctor ka hmuh ang?

Natna nei reng anga i inhriat chuan, emaw, natna tenau tak pawh atanga dam leh turin hun rei tak i mamawh nia i hriat chuan doctor pan ngei ngei tur a ni. I sawifiah theih loh symptom i neih chuan sawi rawh.

I doctor chuan zawhna a zawt ang che a, a enfiah ang che a, a tul chuan a chhan hriat theih nan thisen test a ti ang che.