‘Sulfa’ ruihhlo pek i ni tawh em? Heng Sulfonamides te hi i zir belh leh ang u!

I dam chhungin doctor-in "Sulfa" chi damdawi a lo pe tawh che em? I hre reng mai thei, a nih loh leh i hre tawh pawh a ni mai thei. Mi tam zawkin "sulfa" tih thumal an hriat hian damdawi inang chiah niin an ngai. Mahse a takah chuan damdawi pawl lian tak tak hming (generic name) a ni. Chuvangin vawiinah hian heng sulfonamide te hi eng nge an nih, eng nge an tih, leh an chungchanga hriat tur pawimawh ber berte hi han sawi ila.

Heng sulfonamide te hi eng nge ni tak tak?

A awlsam zawngin sawi ila, sulfonamides hi damdawi chi khat, mihringin laboratory-a siam (synthetic) a ni. An pianphungah an awm lo. Heng damdawi te chemical structure i en chuan an vai hian element sulphur awmna hmun inang an nei vek a ni. Hei hi "sulfonamide" tih hming lo chhuahna a ni.

Chuti a nih chuan heng damdawi te hian engtin nge hna an thawh? Ngaihtuah teh, kan taksaa bacteria lutte hian nung leh darh zel tur chuan ei tur an mamawh a ni. Heng bacteria te hian an mamawh nutrient pakhat chu folate, a nih loh leh vitamin B9 . Heng sulfa damdawi te hian an tih chu bacteria te hian he folate an siam theihna hi a tikhawlo a ni. Chaw ei lova riltam ang mai a ni. Bacteria te hian folate an hloh chuan an inthen thei lo va, an lo thang lian thei lo va, zawi zawiin an thi thin.

Tunah chuan, "Folate pawh kan mamawh a, chuvangin min tichhe dawn lo em ni?" Chu chu zawhna tha tak a ni! Mahse keini, chu chu mihringte hian kan ei leh in atang hian kan mamawh folate kan hmu thin. Kan taksaah folate kan siam lo. Chuvangin heng damdawi te hian chutiang chuan kan cell te chu direct takin an nghawng lo. Chuvangin bacteria tihhlumna kawng tha tak an ni.

Sulfa damdawi hi tunlai ang bawkin a pawimawh hle.

Sulfonamides hi antibiotics hmuhchhuah hmasak ber a ni lo. Mahse kum 1930 chhoa an hmuhchhuah hnuah kum sawm vel chhung chu antibiotics class tha ber leh chak ber an ni. Penicillin a lar hma khan heng sulfa damdawi te hian bacteria infection avanga thihna tihtlem nan nasa takin a pui a ni.

Mahse tunlai hian sulfonamides hi bacteria infection enkawlna atan chauh hman a ni lo. He damdawi chi hi natna chi hrang hrang enkawlna atan hman a ni a, chung zingah chuan zunthlum, thisen sang, HIV hrik kai, leh cancer chi hrang hrang te pawh a tel.

Eng damdawi dang nge sulfonamide group-a tel?

He list hi a sei deuh a, mahse heng damdawi te hi engzat nge hman a nih tih hriatna a pe ang che. Hei hi hmun hnih ah then ila.

‘sulfa allergic’ chanchin hi a dik em?

Ni e, sulfonamide damdawi allergy a awm thei. Khawvel pumah mi 100 zinga mi 3 leh 8 velin sulfa damdawi an allergy an nei a ni. Mahse hei hi antibiotics hman tlanglawn dang, penicillin ang chi allergy rate nen a inang hle.

Mahse hetah hian thil pawimawh tak chu sulfa damdawi pakhat i allergy vang mai mai chuan sulfa damdawi dang zawng zawngah allergy i nei vek dawn lo . Entirnan, mi pakhatin antibiotic Bactrim allergy a neih chuan natna tidamtu Celebrex allergy a neih loh a rinawm hle. A chhan chu damdawi pahnih chemical structure a inang lo.

Chuvangin, sulfa damdawi allergy i neih tawh chuan i doctor hnenah hrilh ngei ang che , chutiang chuan a dang him zawk a rawn pe thei ang.

He damdawi hian side effect emaw risk emaw a nei em?

Damdawi dang ang bawkin sulfonamides hian chhiatna leh hlauhawmna engemaw zat a nei thei a ni.

• Bacterial Resistance: Hun a kal zel a, bacteria thenkhat chu heng damdawi te hi ‘addicted’ an ni thei a, an do thei bawk. Chumi hnuah chuan damdawi chuan chu bacteria chu a thawk tawh lo.
• Side effects na tak: A tlem hle a, mi thenkhat chuan vun natna nasa tak an nei thei. Stevens-Johnson syndrome leh toxic epidermal necrolysis te hi chutiang natna khirh tak pahnih, mahse a tlem hle. Hetiang thil avanga i hlauthawng hma hian i damdawi ei tur chungchang hi i doctor nen sawipui hmasa phawt ila a tha ber ang.

Bactrim hi sulfonamide a ni em?

Ni e, a then chu. Damdawi BactrimTM hian sulfamethoxazole, sulfonamide pakhat leh damdawi dang trimethoprim an tih te a pai a, chutiang bawkin hna a thawk bawk.

Celebrex pawh hi sulfa damdawi a ni em?

Awle. Celecoxib (Celebrex®) hi natna tidamtu a ni a, sulfonamide class-ah a tel a ni.

He damdawi hian zun chhungah crystal a siam thei em?

Sulfa damdawi thenkhat chuan zun chhungah crystal a siam thei a. Hei hi side effect tlanglawn tak a ni lo. I doctor-in pakhat a pe che a nih chuan, chutiang laka invenna atana i tih tur a hrilh ang che (entir nan, tui tam tak in rawh). Chuvangin ngaihtuah buai suh.

Sulfonamides hi damdawi chi khat, test tha tak leh finfiah tawh a ni a, kum 90 chuang zet history a nei a ni. A tir chuan bacteria infection tan chauh an hmang a, tunah chuan lu atanga ke thlengin natna chi hrang hrang enkawlna atan an hmang ta a ni.