Type 1 diabetes i hre tawh em? Hei hi kan taksa ngeia immune system-in haywire-a kal a, pancreas-a insulin siamtu cell-te a beih ṭhinna dinhmun a ni. Hei hi a hlauhawm deuh. Mahse medical science hmasawnna avang hian heng dinhmunte hi enkawl dan thar a lo chhuak ta a ni. Chutiang beiseina thar pakhat chu damdawi Teplizumab tih hi a ni. Hei hi a tih dan a ni a, Type 1 diabetes lo awm tanna a tikhawtlai a ni. Chuvangin vawiin hian he thu hi i hriatthiam theih tur awlsam takin i sawi dawn nia.
Teplizumab hi eng damdawi nge ni?
A awlsam zawngin sawi ila, Teplizumab hi Type 1 diabetes vei theihna tur damdawi a ni a, natna lo awm tan kum tlemte chhungin a tikhawtlai thei a ni. Zunthlum damdawi a ni lo a, mahse natna lo awm tanna a tikhawtlai thung. Chu chu thil lian tak a ni lawm ni?
He damdawi hi Monoclonal Antibody tih pawlah a tel a ni . Chu hming chu i hriat chuan hlauthawng suh. Kan taksa immune system-a sipai (antibodies) te hi an kal bo a, kan cell tha tak takte chu an rawn bei tan ta niin han ngaihtuah teh. Chutih lai chuan heng sipai tihsualte thunun nan hian laboratory-a a bik taka siam protein chi dang chu Monoclonal Antibody an ti a. Teplizumab hian a tih chu insulin siamtu cells te chu tihsual palh avanga immune system hnathawh chu tlem a titawp a ni. Chuvang chuan zunthlum vei hi a tikhawtlai a ni.
He damdawi hi Tzield tih brand name hmangin market ah a awm tlangpui a .
He enkawlna i tan hmaa i doctor hnena i hrilh tur thilte
Hei hi a pawimawh hle. Teplizumab hmanga enkawl i tan hmain a hnuaia thute hi doctor hnenah hrilh hmasak a pawimawh. Heng thilte hian enkawlna hlawhtlinna leh i himna chu direct-in a nghawng a ni.
| Situation i report tur a ni | Engvângin nge chu chu a pawimawh? |
|---|---|
| Tuna hri kai theih dan (e.g. khawsik, khawsik, khuh) . | He damdawi hian immune system hnathawh a tihtlem avangin natna hrik awm tawh chu a na zual thei a ni. |
| Liver natna | Taksa atanga damdawi lakchhuahna kawngah liver hi a pawimawh em avangin liver lama harsatna i neih chuan doctor hnenah i hriattir tur a ni. |
| Thisen chhunga thil awm (red blood cells, white blood cells, platelets) tlahniam . | He damdawi hian thisen peng hrang hrang a tihhniam lehzual thei a, chuvangin a level a hniam tawh chuan a hlauhawm hle. |
| Tun hnaia emaw vaccine lo awm tur emaw | A bik takin live virus vaccine te hian he damdawi hi an inzawm thei a ni. Chuvangin vaccine chungchang hi a kimchangin rawn pe dawn nia. |
| Damdawi dang, ei tur dang emaw, thil dang emaw allergy nei | Hei hi Teplizumab emaw a thil tel emaw allergy i neih leh neih loh hriat a pawimawh hle. |
| Naupai tum emaw, naupai emaw i nih chuan | Naupai laiin he damdawi hi a him leh him loh chungchangah hian data kimchang a la awm lo a, chuvangin hemi chungchang hi i doctor nen inbiakna neihpui tur a ni. |
| Nu hnute pe lai i nih chuan | He information hi damdawi chu nu hnute hmanga naute hnena a kal leh kal loh hriat nan a pawimawh hle. |
Engtin nge he damdawi hi taksaah pek a nih?
Teplizumab hi damdawi in lama hruai leh hman theih a ni lo.
- Hei hi intravenous (IV) infusion angin pek a ni .
- Damdawi in emaw clinic emaw-ah medical team enkawlna hnuaiah tih a ni.
- He enkawlna hi nitin ni 14 chhung pek thin a ni tlangpui.
- Enkawlna i tan hmain he damdawi chungchang chipchiar taka tarlanna special leaflet (MedGuide) pek i ni ang. Ngun takin chhiar fo ang che.
- He damdawi hi naupang kum 8 chunglam tan pawh thil engemaw takah pek theih a ni. Mahse, ngaihtuah tur bik thenkhat chu hriat tur a awm. Hemi chungchang hi i doctor nen sawiho rawh.
Pawimawh:He damdawi hi accident-a i ei tam lutuk nia i hriat chuan Colombo National Hospital-a National Poisons Information Center-ah call nghal la, damdawi in hnai ber Emergency Treatment Unit (ETU)-ah kal nghal rawh.
Damdawi dose khat ka ei loh chuan engtin nge ni ang?
He enkawlna dose tin hi a hun taka ei a pawimawh hle. I enkawlna tur ruahman lawk i kal thei lo a nih chuan i healthcare team te ko nghal rawh.
Enkawl laia ngaihtuah tur thil
He damdawi i ei lai hian i medical team te chuan uluk takin an lo vil reng ang che.
- Blood tests: You will need to have regular blood tests. Hengte hian i thisen chhunga thil awm zawng zawng, thisen var, thisen sen, leh thin hnathawh dan a enfiah ang.
- Infection hlauhawmna: He damdawi hian immune system hnathawh a ti tlem a, chu chuan natna kai theihna a tipung a ni. Khawsik, khawsik, ril na, khuh ang chi symptoms i neih chuan mahni invenna nei lo la, doctor ko nghal rawh. Hemi hun chhung hian mi damlohna hmuna kal hi a tlem thei ang bera kal pawh a tha hle.
- Vaccine: Hei hi a pawimawh hle. Teplizumab i ei atanga kar 6 leh kar 52 inkar ah chuan i taksa hian vaccine i dawn te chu a chhang tha lo zawk thei. Chuvangin vaccine lak i mamawh a nih chuan Teplizumab i ei tawh thu doctor hnenah hrilh rawh. Booster dose lak emaw, vaccination schedule thlak emaw a ngai mai thei.
Damdawi avanga side effect lo awm thei
Damdawi dang ang bawkin Teplizumab hian side effect a nei thei a ni. Ṭhenkhat chu serious tak an ni a, ṭhenkhat erawh chu an awm fo.
| Side effects awm thei chu doctor hnenah hriattir nghal tur a ni | |
|---|---|
| Side effect a awm thei | Hrilhfiahna |
| Allergic Reaction awm thei te | Vun vun rawng, hnim hring, hmai, hmui, lei emaw kawr emaw a hring. |
| Cytokine tihchhuahna natna (CRS) . | Hei hi natna khirh tak a ni a, chu chu immune system-in a rawn beih nghal vat a, na tak a ni. A lan chhuah dan chu khawsik, khawsik, chak lohna, lu na, luak chhuak, thawk harsa, leh thinlung na chak lutuk te a ni thei . |
| Hri kai lan chhuah dan | Khawsik, khawsik, khuh, ril na. |
| Side effects a tlangpuiin a na lo (mahse a awm reng chuan doctor hnenah hriattir tur a ni) . | |
| Kawthalo | Pum a zau a. |
| Lu na | Lu na. |
| Luhai | Luak chhuak ang maia hriatna. |
| Vun a hring chhuak | Vunah hian blister te te emaw, a sen emaw a awm. |
He list-ah hian side effect awm thei zawng zawng a tel lo. Thil danglam tak i tawn chuan doctor rawn la, damdawi lam thurawn dil rawh.
Take-Home Thuchah a ni
- Teplizumab hi Type 1 diabetes damdawi a ni lo a, mahse a natna lo awm tanna chu nasa takin a tikhawtlai thei a ni.
- Hei hi damdawi inah vein pakhat, damdawi lam enkawlna hnuaia specialized treatment pek a ni.
- Enkawl i tan hmain i doctor hnenah i damdawi lam dinhmun zawng zawng, damdawi i ei zawng zawng leh a bik takin vaccine i dawn tawh zawng zawngte kimchang takin hrilh hmasa phawt ang che.
- Enkawl lai hianHri kai chhinchhiahna, khawsik, khuh, emaw Cytokine Release Syndrome (CRS) te lakah fimkhur hle ang che. Heng zinga pakhat emaw a lo awm chuan doctor hnenah hriattir nghal rawh.
- He damdawi chungchanga zawhna i neih chuan zawh tur tha ber chu i doctor a ni . Midang zawhna zawh tur chuan lungngai suh.
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