Nangmah emaw, i chhungte zinga tu emaw hian cystic fibrosis i nei em? Chutiang a nih chuan i doctor chuan damdawi pahnih Tezacaftor leh Ivacaftor tih te inzawmkhawm pill a pe che a ni mai thei. Hei hi Symdeko brand hming hnuaiah i hmu mai thei. Hei hi damdawi bik deuh a ni. Chuvangin vawiin hian he damdawi hian eng nge a tih tak tak tih te, a hman dan dik tak te, eng thil nge fimkhur tur tih te, eng side effect nge a thlen theih tih te hi kawng awlsam tak leh friendly takin i sawi dawn nia.
He damdawi hi eng nge thleng tak tak?
A awlsam zawngin sawi ila, cystic fibrosis hi kan taksaa chi leh tui balance control tu genetic defect avanga lo awm a ni. Chuvang chuan secretion, a bik takin lung leh digestive system-a secretion, mucus ang chi te chu a thim hle a, a sticky hle bawk. Dik tak chuan glue ang mai a ni. He mucus thick tak hian lungah thawk a ti harsa a, natna hrik a thlen fo thei bawk .
Kan taksa cell chhunga kawngkhar te te ang maiin ngaihtuah teh, chu chu cell chhunga chi leh tui a luh leh chhuahna hmun a ni. Cystic fibrosis-ah chuan heng kawngkharte hian hna a thawk tha lo.
Hetah hian heng damdawi pahnih, Tezacaftor leh Ivacaftor te hi an rawn lut a, heng damdawi te hian an tih chu chu gate (protein) tha lo tak takah chuan an kal a, hnathawh dan tur dik takah an pui thin Chutianga chi leh tui inherna a lo awm leh chuan, mucus thick tak chu a liquefies zauh zauh a, lung atang hian awlsam takin a chhuak thei a ni. Tichuan thawk a awlsam a, a natna lan chhuah dan pawh a tam zawkah chuan thunun theih a ni.
Damdawi ei hmaa doctor hnena i hrilh tur thilte
He damdawi hi i ei tan hmain i hriselna dinhmun kimchang doctor hnenah i hrilh hmasak phawt a pawimawh hle . A chhan chu he damdawi hman hian fimkhur bik ngai dinhmun thenkhat a awm avangin. Heng thilte hi a bik takin hrilh ngei ang che.
- Kidney natna i neih chuan .
- Liver natna i neih chuan . Hei hi a pawimawh hle a, a chhan chu he damdawi hi taksa atangin liver kaltlangin a chhuak thin .
- Tezacaftor, Ivacaftor, emaw damdawi dang, ei tur, emaw dye dang emaw allergy i neih chuan .
- Naupai emaw, nau pai tum emaw i nih chuanHmingte.
- Nu hnute pe lai i nih chuan .
Heng thute atang hian doctor chuan he damdawi hi i tan a tha em tih te, a dose thlak a ngai em tih te a rel ang.
Damdawi hi a dik taka hman tur a ni.
He damdawi hi a hlawk ber tur chuan dik taka ei a pawimawh hle.
- Chaw nen ei: He pill hi chaw thau nen ei tur a ni . Entirnan, artui, peanut butter, cheese, bawnghnute, yogurt, emaw chaw ei tur coconut oil tlem te nen. Hei hi damdawi hi a hip luh dan tha ber a ni.
- A rualin ei rawh: I damdawi chu a theih ang angin nitin hun khata ei tum ang che. Zing leh tlai ei inkar darkar 12 vel dah tur a ni.
- Tablet chu a pumin ei rawh: Tablet chu tichhia suh, tikehsawm suh, ei suh. Tablet chu tui glass khat nen a pumin ei rawh . Heng tablets te hi taksaah zawi zawiin a hmin thei tura siam a nih avangin, a tihchhiat chuan damdawi hnathawh dan a tidanglam thei a ni.
- Grapefruit Juice: Thil pawimawh tak dang chu he damdawi hi grapefruit tui nen ei ngai lo tur a ni. Damdawi thatna nasa takin a nghawng thei a ni. Tin, grapefruit ei kha bansan rawh.
- Titawp suh: I doctor-in a tih hma loh chuan i damdawi ei kha titawp suh. I rilru a hahdam pawhin ei chhunzawm zel ang che.
Damdawi ka ei palh a nih chuan engtin nge ni ang?
Pill tam lutuk i ei palh ang tih han ngaihtuah teh. Chutiang a nih chuan , damdawi in hnai ber Emergency Department (ETU) ah tihkhawtlai lovin kal rawh. A nih loh leh Colombo National Hospital-a National Poisons Information Center-ah thurawn dil turin phone la.
Damdawi dose i ei loh chuan engtin nge i tih ang?
Zing dar 8-ah i damdawi ei kha i theihnghilh tih han ngaihtuah teh. Chawhnu dar 12 vel i hriatreng chuan, i dose leh tur thleng darkar 6 aia rei a ni tihna a nih chuan, i hriatreng veleh missed dose kha ei nghal rawh. Mahse i dose leh tur thleng darkar 6 aia rei lo a nih chuan missed dose kha skip la, a hnuaia dose chu a hun ruatah ei rawh. Vawi khatah vawi hnih ei ngai suh.
He damdawi nena inzawm thei damdawi dang
He damdawi hian damdawi dang thenkhat nen a inzawm thei bawk. Chuvangin, i damdawi ei zawng zawng (vitamin, herbal remedies, leh supplement te pawh tel) i doctor hnenah hrilh hmasak a pawimawh hle .
| Damdawi chi hrang hrang | Entirnan |
|---|---|
| Hengte nen hian he damdawi hi ei loh vek tur a ni | |
| Seizure damdawi thenkhat | Carbamazepine, Phenobarbital, Phenytoin te a awm bawk |
| Tuberculosis damdawi thenkhat | Rifampin, Rifabutin tih a ni |
| Herbal supplement a ni bawk | Mithianghlim Johana Wort |
| A in tur a ni | Grapefruit tui tak a ni |
| Hengte nena inzawmna a awm theih avangin doctor hnenah hriattir rawh. | |
| Antibiotics thenkhat | A rilru a hah lutuk chuan a rilru a buai em em a |
| Antifungals a ni | Fluconazole, Itraconazole, Ketoconazole te a awm bawk |
| Immunosuppressant hmanga taksa hriselna tichhe thei | Cyclosporine, Sirolimus, Tacrolimus te a awm bawk |
| Lung natna damdawi a ni | Digoxin a ni |
He list hi a kim lo a, chuvangin i hman zawng zawng chu doctor hnenah hrilh rawh.
Damdawi ei huna fimkhur tur thil
He damdawi i ei lai hian i doctor chuan a lo enkawl reng ang che.
- Regular check-up: I doctor chuan ni ruat saah clinic-ah lo kal turin a hrilh ang che. Hengte hi skip suh. Hei hi i symptoms a that leh that loh hriat nan a pawimawh hle.
- Thisen test: He damdawi i ei lai hian i doctor chuan thisen test tlemte a order mai thei. I liver enzyme te, a bik takin i liver enzyme te an check ang. Hei hi thil pangngai a nih avangin lungngai suh. Damdawi hian i tan hna a thawk a, i liver a nghawng lo tih chian nan a ni.
- Mit enfiah: Damdawi ei tan hma leh ei lai pawhin mit enfiah tir turin an ti thei bawk. I mit hmuhnaah danglamna i hmu a nih chuan (mitna fiah lo, light chhehvela ring hmuh ang chi) , i doctor hnenah hrilh nghal rawh.
Side effect awm thei te chu engte nge ni?
Damdawi dang ang bawkin he damdawi hian side effect engemaw zat a nei thei. Mi zawng zawngin an hmu vek lo. Mahse, anmahni fimkhur a pawimawh.
| Side effect chi hrang hrang | Natna |
|---|---|
| Side effect na tak tak, doctor hnena hriattir nghal tur | |
| Allergy natna a awm thei | Vun vun rawng, hnim hring, hmai, hmui, lei emaw kawr emaw a hring, thawk harsa. |
| Liver hliam chhinchhiahna | Pum dinglam chunglam natna, chaw ei chak lohna, luak chhuak, ekna rawng hring, zun dum emaw, sen emaw, mit emaw vun emaw sen, leh chau danglam taka inhriatna. |
| Mit hmuhna lama inthlak danglamna | Mit hmuh fiah lo, light chhehvel ring hmuh, mit hmuh loh. |
| Side effects nasat loh tlangpui, mahse a awm reng chuan doctor hnenah hriattir tur a ni | |
| Lu na | Lu na tlangpui. |
| Luak chhuak thei | Luak chhuak . |
| Luhai | I luak chhuak dawn ang maia inhriatna (Nausea). |
| Sinus natna | Hmai emaw hmai emaw vel a na emaw, a tight emaw hriatna. |
He list-a tarlan loh symptom dang danglam tak i neih chuan i doctor hnenah pawh hrilh la.
Damdawi hi engtin nge him taka kan dahkhawm ang?
- Naupang lakah hlat rawh: Damdawi hi naupang leh ran vulhte hmuh theih lohna hmunah, hmun khar takah dah fo ang che.
- Temperature dik tak: Room temperature (20 leh 25 degree Celsius inkar)-ah dah tur a ni. Khua lum leh vawt lutuk lakah venghim rawh.
- Damdawi expired: Damdawi expiry date pelh tawh chu hmang suh. Anni chu uluk takin paih rawh.
- Hman dan: Damdawi hman lohte chu toilet hnuaiah emaw, bawlhhlawh bawmah direct-in emaw paih suh. I doctor hnenah an paih dan dik tak zawt rawh.
Take-Home Thuchah a ni
- Tezacaftor-a chuan; Ivacaftor an tih damdawi hi chaw thau tak nen ei fo thin ang che. Hei hian damdawi chu taksain a hip lut tha zawk theih nan a pui thin.
- He damdawi hi i ei lai hian grapefruit emaw grapefruit tui emaw in loh vek tur a ni.
- Damdawi dang, vitamin leh hnam damdawi i ei zawng zawngte chu i doctor hnenah hriattir ngei ang che.
- Dose i miss a nih chuan missed dose chu i dose leh tur thleng darkar 6 aia rei a nih chauhvin ei thin ang che. Chutiang a nih loh chuan skip mai rawh. Dose pahnih chu a rualin ei ngai suh.
- Side effect na tak i neih chuan, mit a inthlak danglam, vun emaw mit a sen emaw a nih chuan doctor rawn nghal rawh.
- He thuziak hi a tlangpui chauh a ni. Doctor thurawn zawm fo ang che.
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