Type 2 Diabetes hi a dam kim thei em? Thu thar ber ber i zawng chhuak ang u!

Kan ramah hian zunthlum hi mi tam tak zingah natna hluar tak a lo ni ta a. I chhungte zinga pakhat emaw, i ṭhian emaw, nangmah ngei pawhin he natna hian a nghawng ve mai thei. A bik takin Type 2 Diabetes hi hriselna lama harsatna lian tak a ni a, khawvel puma mi maktaduai 400 chuangin a tuar a ni. Uluk taka control loh chuan harsatna hlauhawm tak tak, kal chhia, mit hmuh lohna, thinlung natna, leh paralysis te a thlen thei a ni. He natna control nan hian damdawi chi hrang hrang 30 chuang awm mahse, pakhat mah hian a "tidam" vek thei lo. Mahse... zirchianna thar chuan he dinhmun hi a danglam thei tih a tarlang. Engtin nge tih i en ang u.

Hun rei tak chhunga zunthlum chungchanga kan ngaihtuah tawh chu

Kum sawmhnih vel kalta khan mithiam hnenah zunthlum chungchang zawt ta la, hei hi a chhan ber chu ‘insulin resistance’ a ni a ti ang. A awlsam zawngin sawi ila, insulin hi kan pancreas atanga hormone siam a ni. A hnathawh ber chu kan ei leh in atanga glucose (sugar) lo chhuak chu la in kan taksa cell-ah dah a ni. Chu chu cell-te hian chakna an hmuh hun a ni.

Insulin chu chabi angin ngaihtuah la, cell chu kawngkhar angin ngaihtuah bawk ang che. Insulin hi kawngkhar hawngtu chabi a ni a, chutiang chuan glucose chu cell chhungah a lut thei a ni.

Mahse, insulin resistance nei mi cell te hian he insulin hi an chhang tha lo hle. Kawngkhar keyhole chu a rust ang mai a ni. Tichuan, kawngkhar chu hawn theih a nih loh avangin pancreas hian insulin chabi tam zawk a siam a ngai ta a ni. Hun a kal zel a, chutiang taka thawhrimna avang chuan pancreas chu a chak lo ta hle a ni. Chutih lai chuan type 2 diabetes a lo awm ta a ni. Hei hi hun rei tak chhunga kan hriat tawh thawnthu chu a ni.

Thil thar hmuhchhuah pawimawh ber: Beta cell chanchin

Tunah chuan scientist-te chuan buaina chu insulin resistance chauh a ni lo tih an hmuchhuak ta. Buaina chanve dang chu kan beta cells ah a awm a ni . Hengte hi pancreas chhunga awm cell te an ni a, factory tenau tak tak, insulin siamna ang mai an ni.

Kan taksa mamawh beta cell tam zawk hi kan dam chhung kum hmasa berah siam chhuah a ni. Mahse mi thenkhat chu midang aiin beta cell nei tam zawk piang an ni. Chuvangin, nakin lawkah insulin resistance an nei a nih pawhin an beta cell factory-te chuan an compensate turin insulin tam zawk an siam thei a ni.

Chuvangin, tuna thil tum lian ber chu heng beta cell thi mek te hi siam thar leh thei emaw, cell awm zat tipung thei emaw damdawi zawn hi a ni. Chutianga tih theih a nih chuan type 2 diabetes chu tihdam theih a ni ang a, control mai ni lovin.

Beiseina thlentu damdawi thar ber berte

Scientist-te chuan he thil hi an zirchian lai hian heng beta cells te hi tipung thei tur damdawi an hmuchhuak ta a ni. Harmine tih a ni. Khawvel hmun hrang hranga thing chi hrang hranga pianphung anga awm compound a ni.

He damdawi, harmine tia koh hian beta cell chhunga enzyme DYRK1A tih chu block-in hna a thawk a ni. Hei hi block a nih chuan beta cells te chu an inthen tan a, an pung a, an lian chho ta a ni. Mice-a test-naah chuan he damdawi pek hi zunthlum vei mice-te chu beta cell size chu a let thum zetin a pung a ni! Hetih rual hian an thisen sugar level pawh a pangngaiin a lo let leh bawk.

Mahse, hei hi mihringah pawh a hlawhtlin theih nan chuan scientist-te chuan thil dang a ngai tih an hrechhuak ta a ni. Chuvangin, harmine damdawi chu zunthlum natna atana hman tawh damdawi class dang nen an test ta a ni. Chu damdawi class chu GLP1R agonists an ti a . Zunthlum damdawi ei thin i nih chuan heng hmingte hi i hre tawh mai thei: `(exenatide)`, `(liraglutide)`, `(lixisenatide)` te hi he class-a damdawi thenkhat an ni. Beta cells tichaktu leh insulin siamchhuahna tichaktu hmangin hna an thawk a ni.

Chuti a nih chuan, heng damdawi pahnih hi an inzawm khawm chuan eng nge thleng? A result chu a mak khawp mai!

Heng result te hian he enkawlna dan hi mihringah pawh a hlawhtling ngei ang tih rinna nasa tak a siam a ni.

Kan hmaa harsatna awm tur leh engvangin nge hei hi a pawimawh?

Tuna harsatna lian ber chu he damdawi mix hi beta cells-ah direct-a thlen dan tur a ni. Scientist te chuan, "Beta cells tihdamna tur package kan nei a, mahse kan thawn tur address dik tak erawh kan hre lo," an ti. Chumi chinfelna atan chuan monoclonal antibodies tih hming pu thil hman an ngaihtuah a ni. Hengte hi smart courier service ang mai an ni a, kan damdawi package chu beta cell-ah direct-in a thlen thei a ni.

Engvangin nge hei hi a pawimawh em em?

Ngaihtuah teh, tuna zunthlum damdawi hman mek hian thisen sugar level chauh a control a ni. Damdawi i ei tawh loh chuan natna chu a lo lang leh ang.

Tun thlenga permanent solution hnaih ber chu bariatric surgery a ni . Chu chu taksa rihna tihtlem nan surgery tihna a ni. Hei hian zunthlum hi remission-ah a dah fo thin. Mahse khawvela mi maktaduai 400 vel tan chuan surgery hi thil tih theih a ni lo. A man a to a, a risky a, a dam theih nan hun rei tak a ngai bawk.

Mahse he damdawi inkawp thar hi a hlawhtling a nih chuan khawvel hmun hrang hranga mi maktaduai tam takte nun a tidanglam thei a ni. Symptoms chauh a titawp lo va, natna bulpui ber, beta cells hloh hi a siam tha leh a ni.