Wernicke-Korsakoff Syndrome hi eng nge ni? Kan sawi dawn nia!

Thluak leh hriatrengna tichhe thei dinhmun mak tak mai hi i hre tawh em? A châng chuan, kan taksain vitamin ṭhenkhat, a bik takin vitamin B1 ``Thiamine`` an tih chu a tlakchham chuan kan thluak hi nasa takin a chhe thei tih pawh kan hre lo. Chutiang natna khirh tak pakhat chu Wernicke-Korsakoff Syndrome (WKS) a ni. Hei hi emergency treatment mamawh tak tak condition a ni. He thu hi awlsam takin, i hriatthiam theih angin kan sawi dawn em ni?

Wernicke-Korsakoff syndrome (`WKS`) hi eng nge ni tak tak?

A awlsam zawngin sawi ila, hei hi kan thluak leh hriatrengna tichhe thei natna a ni. Hei hi a chhan ber chu kan taksaah hian ‘Thiamine’ (`Thiamine`) emaw vitamin B1 emaw a tlahniam nasa hle a ni. Ngaihtuah teh, kan taksa hi lirthei ang mai a ni. He lirthei engine hi thluak a ni. Engine a kal theih nan gasoline a mamawh a ni. Chutiang bawkin ‘Thiamine` (`Thiamine`) an tih vitamin hi kan thluak leh kan nervous system hnathawh nan a pawimawh hle. He vitamin hian kan eitur chu chakna ah a chantir thin a ni. Chuvangin he ‘Thiamine` (`Thiamine`) hi a tlahniam chuan thluak hian a mamawh chakna a hmu lo va, chutah chuan thluak cell te chu a chhe tan ta a ni.

He `WKS`-ah hian stage lian pahnih a awm a:

1. Wernicke encephalopathy: Hei hi thluaka hliam hmasa ber, rang tak, na tak a ni. Enkawl vat a ngai a ni.

2. Korsakoff syndrome: Hei hi hun rei tak chhunga natna a ni a, hriatrengna nasa takin a nghawng a ni.

German neurologist Carl Wernicke leh Russian neurologist Sergei Korsakoff te hming chawia sak a ni a, anni hian he natna hi an hmuchhuak hmasa ber a ni.

‘Wernicke’s encephalopathy’ leh ‘Korsakoff syndrome’ hi eng nge inzawmna?

An pahnih hi an inzawm tlat a ni. A dik tak chuan ``Wernicke encephalopathy`` an tih hi a hun taka enkawl loh chuan zawi zawiin hriatrengna lama harsatna lian tak ``Korsakoff syndrome`` tih hming puah a lo chang ta a ni.

Wernicke encephalopathy natna lan chhuahna lian ber pathum a awm tlangpui a:

• Buaina: Thil hriatna hloh, hmun leh hun hloh.
• Balance hloh leh chetna thunun theih lohna (`Ataxia`): Kea kal chu a nghet lo va, ke leh ke pawh thunun a harsa ta hle.
• Mit hmuh dan inthlak danglam leh mit lama harsatna: Mit chetna pangngai lo, double hmuh ang chi.

Hei bakah hian a chang chuan taksa ruhte pawh a chak lo thei bawk.

Heng symptoms te hi rei tak a awm reng chuan thluak leh nerve cells te chu a tichhia reng a ni. Hei hi hriatrengna hloh nasa tak a awm a, hriatrengna thar hriatreng theih loh hun a ni. Hei hi ``Korsakoff syndrome`` an ti a.

Wernicke-Korsakoff Syndrome (WKS) hi hun kal zelah a zual zel thei a, nunna atana hlauhawm pawh a ni thei. Chuvangin thiamine hmanga enkawl vat a pawimawh hle. Chutianga tih chuan natna lan chhuahna a tiziaawm thei a, hriatrengna leh thluak hnathawh dangte tihchhiat reng a veng thei bawk.

Nangmah emaw, i hnaih ber emaw pawhin heng symptoms hi an neih chuan doctor pan nghal emaw, damdawi in hnai ber pan emaw tur a ni.

He dinhmun hian tute nge a nghawng ber?

Wernicke-Korsakoff syndrome (WKS) hi hmeichhia aiin mipaah ​​a tam zawk. Kum 30 leh 70 inkar ah a awm tlangpui a, zu in avanga WKS vei tam zawk hi mipa kum 40 chunglam an ni a, mahse hmeichhia leh naupang zawkte pawhin zu tih loh chhan dang vangin he natna hi an nei thei bawk. Naupang tê têah a awm tlem hle.

Tute nge Wernicke-Korsakoff syndrome vei theihna chance sang zawk?

Wernicke encephalopathy hi zu in tam lutuk (alcohol use disorder) te zingah a langsar ber a ni. Zu hi rei tak kan in chuan pum leh chaw ei kawng a tichhe thin. Tin, taksain vitamin a lakluh theihna (malabsorption) a tibuai bawk. Zu in mi 80% velin thiamine an hip thei lo va, an vawng reng thei lo niin an sawi.

Tin, damdawi lam thil engemaw avanga ei tur tha taka ei thei lote pawhin `WKS` an nei thei bawk. Entirnan, taksa rihna tihtlem surgery (`bariatric surgery`) hnuah emaw, cancer natna `chemotherapy` avanga side effect angin emaw a awm thei.

Risk factor dang thenkhat chu hetiang hi a ni:

• Intestinal natna, entirnan, inflammatory bowel disease emaw gastropathy emaw.
• Cancer (a bik takin a nasat chuan).
• Thyroid hormone level sang lutuk (thyrotoxicosis) a awm.
• Genetic mutation thenkhat.
• Hun rei tak chhung lung natna tan diuretic therapy hman.
• Thiamine tlakchhamna natna, HIV/AIDS ang chi te.
• Kidney failure, a chhan chu hun rei tak dialysis hmanga enkawlna hian taksain thiamine a lakluh theihna a tihtlem avangin.
• Damdawi hmun emaw, ei tur tha tak tak emaw hmuh theih lohna.
• Naupai laiin luak chhuak leh luak chhuak tam lutuk (hyperemesis gravidarum).

‘Wernicke-Korsakoff syndrome’ hi engte nge ni?

Hei hi a chhan ber chu ``Thiamine`` tlakchham vang a ni. He vitamin pawimawh tak hian kan ei tur sugar chu chakna ah a chantir thin. Chuvangin ``Thiamine`` kan neih tlem hian kan thluak hian a hnathawh that theih nan a mamawh chakna a hmu lo.

Thiamine tlakchhamna chhan ber chuHun rei tak chhunga zu in tam lutuk. Zu hian taksain thiamine a hip a, thin (liver)-a dahkhawm a harsat phah a ni. Zu hian hna pawimawh dang atana vitamin B1 hman a tibuai bawk.

A chhan dang pawh a awm:

• Ei leh in dik lo: Ei leh in inthlau tak ei loh.
• Ei leh in lama harsatna: anorexia leh bulimia ang chi.
• Infection rei tak awm thei.
• Surgery: A bik takin gastric bypass surgery ang chi, taksa rihna tihtlem nan.
• Traumatic brain injury: Mahse hei hi a tlem deuh.

‘Wernicke-Korsakoff syndrome’ natna lan chhuah dan chu engte nge ni?

Hei hi symptom hrang hrangah a lang thei. Natna khirh tak takah chuan a lan chhuah tam ber pakhat chu ‘confabulation’ a ni. Chu chu i hriatreng loh thil thup nan i rilruah thawnthu siam chhuah tihna a ni. Ngaihtuah teh, mi tu emaw chuan nizan lama an thil tih kha a hre reng lova, mahse a thup bo nan dawt an sawi a, mahse thil thleng tak tak nia an ngaih avangin dawt an sawi lo. A thawnthu chu an ring tlat a ni.

Hetiang natna vei te hian an buai emaw, an rilru a buai emaw fo thei. He buaina hian an tan thil dik lo a awm tih an hriat chian a, inenkawlna zawng a harsat phah a ni.

Wernicke encephalopathy natna lan chhuah dan tlangpui :

• Balance hloh emaw, chetna control theih lohna (ataxia).
• ‘Confabulation’ tih hi a ni.
• Buaina, rilru hahna (delirium).
• Kal harsa, kal dan nghet lo.
• Mutthilh theih lohna.
• Taksa lumna pangngai lo taka hniam (hypothermia).
• Lung lam harsatna: Lung chakna sang (tachycardia) emaw thisen sang hniam (hypotension).
• Muscle coordination hloh (ataxia) a ni.

Mit lama harsatna pawh a awm fo thin:

• Mit chet dan pangngai lo (nystagmus).
• Double vision hmuh theihna.
• Mitmeng chunglam a tlak (ptosis).
• Mit ruh tha lo emaw, chak lohna emaw (ophthalmoplegia).

Wernicke encephalopathy hi enkawl loh a nih chuan Korsakoff syndrome-ah a kal thei a, hei hi hun rei tak chhunga hriatrengna lama harsatna a ni. A natna lan chhuah dante chu:

• Hriatrengna hloh vek (`Amnesia`) emaw thil thar hriatreng theih lohna emaw.
• Nungchang inthlak danglamna: thinrim, thinrim rang.
• ‘Confabulation’ tih hi a ni.
• Delirium leh ngaihtuahna tihbuai (disorientation).
• Chauhna emaw, rilru hahna emaw.
• Hallucinations, a bik takin zu in loh hunah.
• Thil ngaihtuah theih lohna.
• Kalna nghet lo.

Symptom thenkhat chu enkawl pawhin a tha kim lo. A nasat chuan hriatna hloh (`coma`) a awm thei. Nangmah emaw, i hnaih ber emaw chuan i hriatna a hloh a nih chuan, emaw, `Wernicke-Korsakoff syndrome` symptoms i neih chuan doctor pan emaw, emergency room-ah emaw kal nghal rawh.

Engtin nge ‘Wernicke-Korsakoff syndrome’ hi hriat chhuah a nih?

He `WKS` dinhmun hi a hmaa hriatchhuah hi enkawlna hlawhtling tak neih nan a pawimawh hle. Doctor-te chuan taksa enfiahna an neih a, i natna lan chhuah dan an zawt a, i chhungkaw chanchin an zawt a ni. Mahse, mi pakhatin a buai emaw, a hriatrengna a hloh emaw chuan hriat a harsa thei hle.

Doctor chuan heng thilte hi a bik takin a enfiah ang:

• Zu in lama harsatna (`Zu hmansualna`) a awm em?
• Malnutrition a awm em?
• Thiamine tlakchhamna a awm em?

Eng test nge Wernicke-Korsakoff syndrome hriat theihna tura puitu?

I doctor chuan i thisen sugar leh thiamine level enfiah turin thisen test a ti ang. Zu in hman leh hman loh enfiah nan thisen zu test leh liver function endik turin liver function test pawh an ti thei bawk a, hei hian liver chhiatna a lantir thei a ni.

Test dang pawh tih belh theih a ni a, a chhan dang a awm leh awm loh enfiah leh theih a ni:

• ‘Arterial blood gas’ (ABG) test hmangin thisenah carbon dioxide leh oxygen awm zat a enfiah thin.
• 'Thisen chhiar kim' (`Thisen chhiar kim - CBC`).
• Toxicology screening neih a ni.

Heng ang imaging test te pawh i neih a ngai mai thei bawk:

• 'CT scan' tih a ni.
• 'MRI' (`MRI`) tih a ni.
• ‘Electrocardiogram’ tih (`Electrocardiogram - EKG`) tih a ni.

Wernicke-Korsakoff Syndrome hi tihdam theih a ni em? Engtin nge enkawl a nih?

Dik tak chuan tihdam theih a ni lo. Amaherawhchu, a hmaa enkawl tan a nih chuan a natna lanchhuahna chu a reh thei a, a then chu a let leh thei bawk. Hei hian a awmzia chu ``Wernicke encephalopathy`` natna chu a zual zel atanga ``Korsakoff syndrome`` thlenga tihtawp theih a ni tihna a ni.

A tam zawkah chuan enkawlna hian natna lan chhuah dan, rilru buai, mit lama harsatna, leh balance hloh te chu a control thei a, a tichangtlung thei bawk. I doctor chuan i tana tha tur treatment plan a siam ang.

Enkawlna atan a hnuaia mite hi tih a ni tlangpui:

• Pill emaw injection emaw hmanga vitamin B1 pek.
• Taksa tui a tlakchham chuan ``IV fluids`` hmangin saline pek tur a ni.
• Zu in chungchanga harsatna awmte enkawl.
• Nutritional support pek.
• A tul chuan damdawi dang pe bawk ang che.

Engtin nge he natna hi i vei theihna tur i tihziaawm theih ang?

A tam zawkah chuan zu in tihtawp emaw tihtlem emaw hi Wernicke-Korsakoff syndrome vei theihna tur tihtlem nan i tih theih pawimawh ber a ni. Tin, ei leh in tha neih leh a tul chuan thiamine supplement injection emaw pill emaw ang chi ei hian i hlauhawmna a tihziaawm thei a, a bik takin zu ruihhlo ngawlvei tan chuan.

Wernicke-Korsakoff syndrome vei tan chuan eng prognosis nge a awm?

Nangmah emaw, i hnaih ber emaw pawhin he natna hi i neih chuan, a natna lan chhuah dan a nasat dan leh natna hmuhchhuah leh enkawl thuai danah a prognosis a innghat a ni. Enkawl hmasak hian natna lan chhuah dan a tidanglam thei a, hun rei tak chhunga harsatna awm thei tur pawh a veng thei bawk. Mahse, enkawl loh chuan rualbanlohna leh thihna thlengin a thlen thei a ni.

Hetiang dinhmun hi engtikah nge doctor thurawn i lak ang?

Nangmah emaw, i hriat emaw chuan Wernicke-Korsakoff syndrome symptoms a neih chuan doctor pan nghal rawh. I doctor ko emaw, damdawi ina emergency room hnai ber pan emaw, emergency treatment i neih a ngai mai thei.

Engtin nge ka in enkawl ang?

Wernicke-Korsakoff syndrome diagnosis dawn hi thil awlsam a ni lo. Damdawi inah dah a ngai mai thei a, enkawlna i dawng a ngai mai thei. A pawimawh ber chu i doctor thurawn zawm hi a ni a, chu chu zu in tihtlem (a nih loh leh tihtlem vek) leh ei leh in tha tak ei te hi a ni. Heng thilte hian i dam lehna tur chu nasa takin a pui dawn a ni.

I doctor thupek chu uluk takin zawm la, complication te enkawl dan tur leh symptoms te enkawl tur a ni. I tan a tha tur personalized care plan a siam ang a, i hriselna a lo awm leh theih nan a pui ang che.

Wernicke-Korsakoff syndrome hi hriatrengna lama harsatna awm lo mahse na tak a ni. A natna lan chhuah dan tihziaawmna tur leh harsatna a awm loh nan enkawl vat a ngai a ni. Natna a zual zel chuan nervous system-a symptoms, buaina nasa tak leh ngaihtuahna buai tak tak te a lo lang thin. Heng symptoms te hian nangmah emaw, i hnaih ber emaw tan i dinhmun hriat a harsat phah thei a ni. Chuvangin natna hi hriat hmasak a pawimawh. I doctor chuan i mamawh ang zela enkawlna tur ruahmanna a rawn rawt ang che.

Hriat reng tur pawimawh ber berte (Take-Home Message) .

Okay, chuvangin kan sawi tawh `Wernicke-Korsakoff Syndrome` chungchanga hriat reng tur pawimawh tak takte chu hetiang hi a ni:

• Hei hi thiamine (vitamin B1) tlakchhamna avanga thluak leh hriatrengna tichhe thei natna khirh tak a ni.
• Risk factor ber chu zu in tam lutuk hi a ni.
• Stage hmasa ber chu Wernicke encephalopathy a ni a, enkawl loh chuan hun rei tak chhunga hriatrengna lama harsatna, Korsakoff syndrome tih chu a thlen thei a ni.
• Buaina, kal harsa, mit lama harsatna, leh hriatrengna hloh te hi a lan chhuahna ber a ni thei.
• Rapid diagnosis leh thiamine hmanga emergency enkawl a pawimawh hle.
• Dam vek theih ni lo mah se, a hmaa enkawl hian natna lan chhuah dan a thunun thei a, a chhiatna awm reng tur a veng thei bawk.
• Nangmah emaw, i hriat miin emaw heng symptoms te hi a lantir a nih chuan doctor thurawn zawng nghal rawh.

He thu hi i tan a tangkai ngei ka beisei. Hrisel takin awm rawh!

` Wernicke-Korsakoff syndrome, thiamine tlakchhamna, vitamin B1, zu in, hriatrengna lama harsatna, thluak lama harsatna, thluak lam natna