Kua whakaaro kē koe me pēhea te whakaputanga o ēnei toto toto whero, arā, ngā toto toto whero , i roto i ō tātou tinana? He tukanga whakamiharo, he uaua, he mea nui hoki tēnei mō ō tātou oranga. I tēnei rā ka kōrero tātou mō te whakaputanga o ēnei toto toto whero, e kiia ana tēnei e tātou i roto i te rongoā ( Erythropoiesis). He rite tēnei ki tētahi wheketere iti i roto i ō tātou tinana, e whakaputa tonu ana i ngā toto toto whero hou.
He aha te Erythropoiesis? He aha te hiranga ki a tātou?
Ki te kī māmā noa, ko te (Erythropoiesis) te tukanga e hanga ai e tō tinana ngā toto whero (i roto i te rongoā, ka kiia hoki tēnei ko ngā "Erythrocytes"). Mā tēnei tukanga ka tika te nui o ngā toto whero i roto i ō tātou tinana – kaua e iti rawa, kaua hoki e maha rawa. Whakaarohia te hiranga o ēnei toto whero ki ō tātou tinana!
Ko rātou ēnei:
- Ina manawa tātou, ka uru te hāora ki roto i ngā pukahukahu, ka haria ki ngā kiko me ngā pūtau katoa o te tinana. He rite ki ngā kaikawe mēra iti i roto i ō tātou tinana.
- Waihoki, ko te hauhā waro e hangaia ana i roto i ngā kiko o te tinana ka whakahokia ki ngā pukahukahu, ka tukuna ki waho ina puta te manawa.
Nō reira, e kite ana koe, kāore e taea e tātou te ora me te kore ēnei toto whero. He hauora tātou nā te mea kei te tika te tukanga e kiia nei ko te erythropoiesis.
Ko te Erythropoiesis tētahi wāhanga o tētahi tukanga nui ake. Ko te tukanga katoa o te hanga i ngā momo pūtau toto e toru i roto i tō tātou tinana e kiia ana ko te " Hēmatopoiesis ".
- Ko te tukanga hanga toto whero e kiia ana ko te "Erythropoiesis" (koinei te mea e kōrerohia ana ināianei).
- Ko te tukanga hanga o ngā pūtau toto mā e kiia ana ko te "Leukopoiesis".
- Ko te hanga o ngā pereti toto (ngā pūtau e āwhina ana ki te toto totoka) e kiia ana ko te "Thrombopoiesis".
Kei hea tēnei (Erythropoiesis) e puta ai?
Ka rerekē te wāhi e hangaia ai ēnei pūtau toto whero i roto i te wā.
I te wā kei roto te pēpi i te kōpū (te erythropoiesis fetal)
Ka tīmata tēnei (Erythropoiesis) i mua i tō tātou whānautanga, arā, i a tātou e noho tonu ana i roto i te kōpū o tō tātou whaea.
- I te toru wiki pea: Ka tīmata tēnei i roto i tētahi hanganga e kiia nei ko te "Pūke Huamata " e whāngai ana i te kukune.
- I muri i ngā marama e rua, e toru rānei: Whai muri i tēnā, ka hangaia ngā toto whero i roto i te ate me te whēkau o te pēpi.
- Tata ki te rima marama: Ka tīmata tēnei tukanga i roto i te hinu wheua o te kukune. Ko te hinu wheua te wāhanga ngohengohe, rite ki te hautai i roto i ō tātou wheua.
Tamariki me ngā pakeke (Erythropoiesis)
I muri i tō tātou whānautanga, ko te nuinga o ngā pūtau toto whero ka hangaia i roto i ō tātou tinanaI roto i te hinu wheua .
- Tamariki: I te wā tamarikitanga, ka hangaia ngā toto whero i roto i te hinu wheua o te maha o ngā wheua o te tinana.
- Ngā Pakeke: I a tātou e pakeke haere ana, ka mahi noa tēnei i roto i ētahi wheua. Hei tauira, i ngā wāhi pēnei i te hope, ngā tuaiwi, ngā rara, me te uma.
He aha te rerekētanga i waenga i te erythropoiesis Medullary me te erythropoiesis Extramedullary?
Ahakoa te ahua uaua o ēnei kupu e rua, he ngāwari noa iho te mārama.
- Ko te tikanga o te kupu `(Medullary)` he mea e pā ana ki te hinu wheua. Nō reira, ko te tikanga o te kupu `(Medullary erythropoiesis)` ko te hanganga o ngā toto whero i roto i te hinu wheua. Koinei te āhua noa.
- Ko te erythropoiesis extramedullary e pā ana ki te hanganga o ngā pūtau toto whero i waho o te hinu wheua, pērā i te ate me te whēkau.
I te wā o te kukune, he mea noa tēnei (extramedullary erythropoiesis). Engari ki te pā ki te pakeke, he tohu pea tēnei mō tētahi mate, raruraru rānei i roto i te hinu wheua. Kātahi ka tirotirohia e ngā tākuta.
He aha ngā wāhanga o te hanganga o ngā pūtau toto whero?
Kāore te toto whero e hangaia katoatia i te wā kotahi, he haerenga e haere ana i roto i ngā wāhanga maha. He rite ki te anuhe e huri ana hei pūrerehua.
Ka tīmata ēnei pūtau toto katoa i tētahi pūtau taketake kotahi. Ka kiia e mātou he "pūtau take Hematopoietic" (HSC) . He rite tēnei ki tētahi "pūtau matua." Ka taea e tēnei pūtau HSC te huri hei tetahi o ēnei pūtau toto whero, hei pūtau toto mā, hei pereti toto rānei.
Ina hangaia he toto whero, ka huri tuatahi tēnei pūtau HSC hei pūtau e kiia nei ko te "Common myeloid progenitor" (CMP) . Ka taea hoki e tēnei pūtau CMP te huri hei toto whero, hei pereti toto, hei ētahi momo toto mā rānei. Muri iho, ka whanake te pūtau CMP ka huri hei toto whero hei "Megakaryocyte-erythroid progenitor cell" (MEP) .
Kia riro hei MEP, kei te anga whakamua taua pūtau ki te huri hei toto whero. Kātahi ka haere i roto i ētahi atu wāhanga:
- `(Proerythroblast)` (Proerythroblast)
- `(Erythroblast)` (Erythroblast)
- `(Normoblast)` (Normoblast)
- `(Reticulocyte)` (Reticulocyte) - He toto whero taitamariki tēnei.
- Hei whakamutunga, ka huri hei "Erythrocyte" kua tino pakari, arā, he toto whero e mōhiotia ana e tātou.
Ka tukuna ēnei toto whero kua tino hangaia ki roto i te toto mai i te hinu wheua. Ko reira ka tīmata ai tā rātou mahi tino nui - te kawe i te hāora me te tango i te hauhā waro.
Kia pēhea te roa o tēnei tukanga?
E tata ana ki te wiki te roa kia tino hangaia ai te kotahi pūtau toto whero.
He aha te roanga o te ora o te toto whero?
Kotahi te toto whero e ora ana i roto i tō tātou tinana mō te tata ki te 120 ngā rā.Ara. Kātahi ka mate aua pūtau, ka puta mai he pūtau hou hei whakakapi i a rātou. He huringa tēnei e tupu tonu ana.
He aha te mea e whakahaere ana i tēnei (Erythropoiesis)?
He tino mīharo te whakahaere a ō tātou tinana i tēnei tukanga (Erythropoiesis). Ko te mea nui ko te taumata o te hāora i roto i ō tātou tinana.
Whakaarohia, ki te kore e nui te hāora e whiwhi ana i ō kiko (e kiia ana tēnei āhuatanga ko te "Hypoxia"), ka tere ake te hanga o ngā toto whero i roto i tō tinana. Nā te mea ka piki ake ngā toto whero, ka piki ake hoki te nui o te hāora e haere ana ki ngā kiko.
Ka whakaohokia tēnei tukanga (Erythropoiesis), arā, ka whakahohehia, e tētahi homoni motuhake. Ko tōna ingoa ko te `(Erythropoietin)` (EPO ).
He aha tēnei (Erythropoietin - EPO)?
Ko te Erythropoietin (EPO) he homoni e whakanui ana i te hanga o ngā toto whero. He rite ngā homoni ki ngā karere matū e whakarite ana i ngā mahi rerekē i roto i tō tātou tinana. Ko te nuinga o te EPO e hiahiatia ana e tō tātou tinana ka hangaia e ō tātou whatukuhu .
Anei te āhua o tēnei:
1. Nā te iti o te maha o ngā toto whero, kāore e nui te hāora e whiwhi ana i roto i ō kiko tinana.
2. Hei whakautu i tēnei, ka nui ake te homoni EPO e tukuna ana e ō whatukuhu.
3. Ka whakaohokia e tēnei homoni EPO tō hinu wheua kia nui ake ngā pūtau toto whero.
4. I te pikinga ake o te maha o ngā toto whero, ka piki ake anō hoki te nui o te "(Hemoglobin)" (te pūmua e kawe ana i te hāora) i roto i a rātou. Ina rongo ngā whatukuhu i tēnei, ka whakaitihia e rātou te whakaputanga o te EPO.
5. Mā tēnei, ka mau tonu te maha o ngā toto whero i roto i tō tātou tinana ki tētahi taumata. Ka kiia tēnei taurite ko "(Homeostasis)" (homeostasis).
Kei te whakaputa tonu ā tātou whatukuhu i tētahi iti o te EPO hei ārai i te hanganga o ngā toto whero. Nā te mea e mate ana te 1% o ā tātou toto whero i ia rā, ko te (Erythropoiesis) te mea e whakakī ana i taua ngoikoretanga.
Mena ka rerekē te taumata o ngā toto whero nā te mate, nā te aituā rānei, ka whakanui, ka whakaiti rānei ngā whatukuhu i te hanga EPO.
He aha te mea ka tupu mēnā he raruraru kei roto i te erythropoiesis?
Mena he raruraru, he hapa rānei kei roto i te tukanga hanga toto whero, tera pea he iti ake , he nui ake rānei ō toto whero.
- Te iti o te maha o ngā toto whero: Ka kiia tēnei ko te anemia . Ko te tikanga tēnei kāore e nui te hāora e whiwhi ana i ngā kiko o tō tinana. Ka taea e tēnei te whakararuraru i a koe , te ngenge tonu, ā, i ētahi wā ka makariri hoki . He rerekē ngā momo anemia.
- Te pikinga o te maha o ngā toto toto whero: Ka kiia tēnei ko te `(Erythrocytosis)` (erythrocytosis). Ina tupu tēnei, ka pāngia pea koe e ngā tohu iti pēnei i te ānini me te ngenge. Heoi, i runga i te take, ka arahi pea ki ngā raruraru nui pēnei i te toto totoka .
He aha ngā āhuatanga ka pā ki te erythropoiesis?
He maha ngā mate me ētahi atu āhuatanga ka pā ki te whakaputa me te whakahaere i ngā pūtau toto whero i roto i tō tātou tinana.
Ngā mate e pā ana ki te pūkahukahu
Ka taea e ēnei te whakaiti i te nui o te hāora e whiwhi ana te tinana, ka rerekē ai te hanga EPO.
- Mate huango
- Te mate pūkahukahu ārai mau tonu (COPD)
Ngā mate pukupuku e pā ana ki te toto, ki te wheua rānei
Ka taea e ēnei te whakararuraru tika i te tukanga hanga toto whero.
- Leukemia
- Lymphoma
- Myeloma
- Ngā mate myeloproliferative
Ētahi atu take
- Ngā ngoikoretanga o te kai: Ina koa ko te korenga o te rino, te huaora B12, me te waikawa folic (waikawa folic) ka arahi pea ki te ngoikore o te hanga toto whero. Koinei ngā poraka hanga e hiahiatia ana hei hanga toto whero.
- Te noho ki ngā teitei: I ngā teitei, he iti ake te hāora i te rangi. Nō reira, hei urutau, ka nui ake te EPO e whakaputaina ana e te tinana, ā, ka whakanuia ake te hanga o ngā pūtau toto whero.
Ka hangaia e ō tātou tinana he toto whero hou i roto i ō tātou oranga. Ina mate ngā pūtau tawhito, ka kite te tinana i ēnei huringa, ā, ka whakanui ake i te hanga EPO, ā, ka whakanui ake i te hanga o ngā toto whero. Hei pupuri i te hauora o te hāora ki ō tātou kiko, me tika te maha o ngā toto whero. Waimarie, ka whakahaere aunoa te tinana i tēnei tukanga, me te kore he kaha mai i a tātou. Heoi, ki te pāngia koe e tētahi mate e whakararuraru ana i tēnei tukanga (erythropoiesis), ka taea e tō tākuta te rongoā, te whakahaere rānei i taua mea.
Ngā mea tino nui hei maumahara (Karere hei kawe ki te kāinga)
- He tukanga tino nui te erythropoiesis e whakaputa ana i ngā pūtau toto whero i roto i tō tātou tinana.
- Ko ēnei pūtau toto whero te hunga e kawe ana i te hāora puta noa i ō tātou tinana , ā, e tango ana hoki i te hauhā waro.
- I roto i tō tātou hinu wheua te nuinga o tēnei tukanga e puta ai.
- Ko te homoni e kiia nei ko te Erythropoietin (EPO) , e hangaia ana e ngā whatukuhu, ka āwhina i te whakahaere i tēnei tukanga.
- Ka pā mai pea ngā raruraru o tēnei tukanga ki te anemia (te hekenga o ngā toto whero) te erythrocytosis rānei (te pikinga ake o ngā toto whero).
- He mea nui te erythropoiesis tika mō te oranga hauora. Mena he pātai, he ruarua rānei āu mō tēnei mea, me rapu tohutohu hauora .
Nō reira, ko tāku tumanako kua mārama kē koe ki tēnei tukanga whakamiharo e kiia nei ko (Erythropoiesis). He maha ngā mea e tupu ana i roto i ō tātou tinana kāore anō kia mōhiotia e tātou, tika?
Ngā toto whero, te erythropoiesis, te hinu wheua, te anemia, te hāora, te erythropoietin, te whatukuhu











💬 Comments (0)
Kaore ano kia tukuna he korero. Tāpirihia to korero ki konei mo te wa tuatahi.
Tāpirihia to korero