He whakarāpopototanga o te Blastocyst: Te taahiraa tuatahi i roto i te hāputanga hauora (Blastocyst)

Mena he tangata koe e tumanako ana ki te whānau tamariki, inā koa kei te rongoatia koe mō te kore tamariki, kua rongo pea koe i te kupu 'Blastocyst' mai i tō tākuta. He maha ngā wā ka rangona tēnei kupu, inā koa ka kōrerohia ngā maimoatanga pēnei i te IVF. Ina rongo koe i tēnei, tera pea he ahua pūtaiao, he uaua hoki ki a koe. Engari kaua e wehi. Ki te kī noa, koinei te tīmatanga iti rawa, engari he tino nui o tō tumanako. I tēnei rā, ka kōrerohia e tātou he tino māmā, he hoahoa hoki mō te aha tēnei Blastocyst, tana mahi, me tōna hiranga mō te hapūtanga.

He aha te Blastocyst?

Whakaarohia, i muri i te whakamomonatanga o te hua manu o tētahi wahine hauora e te parāoa o tētahi tāne hauora, ko te pūtau tuatahi e puta mai ana ka kiia he zygote. Ka tīmata te wehewehe tere o taua pūtau. Ka huri te kotahi hei rua, ka huri te rua hei whā, ā, ka pērā tonu, ka hanga he hanganga pōro iti e kiia nei ko te blastocyst .

Ki te kī ngāwari, ko te blastocyst te wāhanga tino tīmatanga o te kukune . Ka puta i te rima ki te ono ngā rā i muri i te whakatōngia o te hua manu e te parāoa. He tohu nui tēnei i roto i te tukanga hapūtanga. Koinei te wā e honoa ai ēnei pūtau, e piri ai ki te pakitara o te kōpū. Ka kiia tēnei ko te whakatōnga.

He mea tino nui tēnei wāhanga Blastocyst i roto i te IVF (In Vitro Fertilization) nā te mea ka taea e ngā tākuta te whiriwhiri i te Blastocyst hauora me te tino whanake ka whakatō ki roto i te kōpū o te whaea. Mā tēnei ka piki ake te tūponotanga o te haputanga angitu.

Me pēhea te tukanga o te haputanga o te tamaiti?

Hei mārama katoa ki te hiranga o te blastocyst, he mea āwhina kia whai whakaaro iti ki te tukanga katoa o te haputanga o te tamaiti. Me titiro tātou ki te whanaketanga o tēnei haerenga whakamiharo i ia taahiraa.

1. Te Whakatōnga Hua: I te nuinga o te wā, tata ki te 14 ngā rā i muri i te tīmatanga o te paheketanga o te wahine, ka tukuna he hua kua pakeke (hua manu) mai i tētahi o ana ovaries. Ka haere tēnei hua manu ki raro i te ngongo fallopian ka tatari kia whakatōngia e te parāoa.

2. Te Whakatōtōtanga: Mena ka puta te moepuku i tēnei wā, ka taea e te parāoa te tūtaki ki te hua manu i roto i te ngongo fallopian ka hono atu ki a ia. Koinei te mea e kiia nei e tātou ko te whakatōtōtanga.

3. Te Hanganga o te Zygote: Ka kiia e tātou te hua manu kua whakatōkia he 'zygote'. Koinei te pūtau kotahi tuatahi e whakakotahi ana i ngā ira o te whaea me te pāpā.

4. Te Haerenga ki te Wāhanga Blastocyst:Ka haere tēnei zygote i roto i te ngongo fallopian ki te kōpū mō te toru ki te rima rā. Kāore e noho noa iho i reira, engari ka wehea tonutia. E rua, e whā, e waru ngā pūtau... ka tere te wehea, ā, ka huri hei pōro iti me ngā rau pūtau me te kōhao i roto. Koinei te mea e kiia nei e tātou he Blastocyst .

5. Te Whakatōnga: I muri i te taenga ki te kōpū, ka noho te blastocyst ki reira mō ētahi rā, ka piri ki te pakitara o roto o te kōpū (endometrium). Koinei te mea e kiia nei e tātou ko te 'whakatōnga'.

6. Te kukune me te tamaiti: Whai muri i te whakaurunga ki roto i te kōpū, ka haere tonu te wehewehe me te tipu o ēnei pūtau hei kukune. I muri i te 9 wiki pea, ka whanake tonu tēnei kukune ka huri hei kukune, koinei te āhua katoa o te pēpi e mōhiotia ana e tātou.

He aha te mahi a te blastocyst? He aha te hiranga o tēnei?

He wāhanga tino nui, ā, he wāhanga e kore e taea te karo te wāhanga blastocyst i roto i te whanaketanga o te kukune me te tamaiti. Ko te take māmā noa iho, ki te kore te blastocyst e whakatō tika ki roto i te pakitara kōpū, e kore e puta te haputanga.

Ka puta tēnei whakaurunga mā roto i tētahi tukanga whakamiharo. I raro i te mana o ngā homoni i roto i ō tātou tinana, ka pāngia te blastocyst e tētahi tukanga e kiia nei ko te "pao." Pērā i te pīpī e pao mai ana i te hua manu, ka pakaru te blastocyst mā roto i tōna kiriuhi angiangi o waho (zona pellucida). Ka puta tēnei i roto i te rā, i te toru rānei o tōna whakaurunga ki roto i te kōpū.

Kātahi ka puta te mahi tuturu. E rua ngā paparanga pūtau i roto i te blastocyst.

• Te Toropūpū: Ko ēnei pūtau te tuatahi ki te piri ki te pakitara o te kōpū. Mā te whakaputa i tētahi pūmua piri (L-selectin), he rite ki te kāpia. Ā muri ake nei, ka hangaia e ēnei pūtau te whenua uri . He okana tino nui te whenua uri e whakarato ana i te hāora me ngā matūkai ki te pēpi, ā, e tango ana hoki i ngā para mai i te pēpi.
• Papatipu pūtau o roto: Ka whanake tēnei papatipu pūtau hei tamaiti i roto i te kōpū i muri mai.

Ka huihui ētahi pūtau o te whenua whānau hei hanga i te pēke amniotic, arā, te pēke wai tiaki e karapoti ana i te pēpi.

He aha ngā tohu o te whakaurunga o te blastocyst?

Ko te nuinga o te tangata kāore e pāngia e tetahi tohu i tēnei wā. Engari ko ētahi tāngata, tata ki te hautoru, ka pāngia pea e ētahi tohu. Koinei pea te tohu tuatahi e hapu ana koe. Engari ehara i te katoa e pāngia ana e ēnei tohu, ā, ki te pāngia koe e ēnei tohu, ehara i te mea kei te hapu koe. Nō reira, he pai tonu te kōrero ki tō tākuta.

Ka taea e te Blastocyst te whakawhanau tamariki?

He kaupapa tairongo tēnei hei kōrero, engari he mea nui kia mōhio. Ae, ka taea e te blastocyst te whānautanga kore, te kore rānei e whakatō pai. Inaa, tata ki te 75% o ngā whānautanga kore wawe rawa nā te korenga o te whakatō pai o te blastocyst.

He aha tēnei e tupu nei?

Ko te take matua mō tēnei ko ngā āhuatanga rerekē o te ira tangata.Ina wehea ngā pūtau o te blastocyst, i ētahi wā ka puta he raruraru ki ngā chromosome. Hei tauira, tera pea he chromosome tāpiri, he chromosome ngaro, he wāhanga rānei o te chromosome ka whati.

Ina kore e angitu te whakatōnga i tēnei ara, ka tīmata pea te hāputanga engari ka mutu wawe rawa (tata ki te 5 wiki). Koinei te mea e kiia nei e mātou he "hāputanga matū". Ki te kore tō paheketanga e roa, ki te kore rānei koe e whakamātautau hāputanga, tērā pea kāore koe e mōhio kua tupu tēnei.

He tino onge te whakatōnga o tētahi blastocyst me te rerekētanga o te ira tangata, ā, ka taea te haputanga. I roto i ēnei āhuatanga, tera pea ka pāngia te pēpi e ngā mate pēnei i te Down syndrome, te Klinefelter syndrome, te Turner syndrome rānei.

He huarahi hei kite i ēnei raruraru ira i mua i te wā o te IVF?

Āe, me te whanaketanga o te rongoā hou, kei reira he otinga mō tēnei. I te wā o te maimoatanga IVF, i mua i te whakaurunga o te blastocyst ki roto i te kōpū, ka taea te tango i ētahi pūtau mai i reira ka whakamatautauria mō ngā raruraru ira.

Ko te ingoa o tēnei whakamātautau ko te Whakamātautau Ira i mua i te whakatōnga (PGT) .

Mā tēnei whakamātautau, ka taea e ngā tākuta te whiriwhiri i te blastocyst tino hauora o te ira tangata hei whakatō ki roto i te kōpū. Nō reira,

• Ka piki ake te tūponotanga o te haputanga angitu.
• Ka whakaitihia te mōrearea o te materoto wawe.
• Ka taea e ia te whakaiti i te mōrearea o te whānautanga o tētahi tamaiti me ngā āhuatanga rerekē o te ira tangata.

Mō te tangata e hapu ana i roto i te taiao, ka taea anake te mahi i ēnei momo whakamātautau i muri i te 9, i te 10 wiki rānei o te hapūtanga.

Ka taea te whakaiti i te mōrearea o ngā rerekētanga o te ira tangata?

Engari, kāore e taea e tātou te whakahaere i ētahi āhuatanga mōrearea.

• Neke atu i te 35 tau te pakeke.
• He hītori whānau kei roto i te whānau o ngā mate chromosome.
• Kua pāngia e ngā materoto o mua, kua whānau rānei he pēpi me te raruraru ira tangata.

Mena kei a koe ēnei āhuatanga mōrearea, he mea tino nui kia kōrero koe ki tō tākuta me tētahi kaitohutohu ira ina whakamahere koe ki te whānau tamariki.

Heoi anō, kei reira ētahi mea ka taea e tātou te whakahaere. Mā te whai i tētahi momo noho hauora i mua atu, i muri mai hoki i te hapūtanga, ka taea e tātou te whakaiti i te tūponotanga o te kino ki te tamaiti kei roto i te pēpi.

• Āraia te pānga o ngā matū paitini.
• Āta karohia te whakamahi i ngā raau taero me te waipiro.
• Kai i te kai taurite.
• Tangohia ngā huaora e tika ana kia rite ki ngā tohutohu a tō tākuta.

He tīmatanga nui te blastocyst ki tētahi hāputanga hauora. Ki te kore e tupu pai, ā, ki te kore e whakatōkia ki roto i te kōpū, e kore e puta te hāputanga. Ki te pāngia koe e tētahi ira iti, mamae rānei i ngā wāhanga tōmua o te hāputanga, kaua e mataku, kaua hoki e wareware, engari me toro atu ki tō tākuta tonu mō ētahi tohutohu. Ka taea e ia te tirotiro i a koe me te whakarite kei te pai ngā mea katoa.