Ka taea e te mate pukupuku te horapa ki ō wheua? (Bone Metastasis) Me kōrero tātou mō tēnei!

Kua rongo pea koe i tētahi tangata e pangia ana e te mate pukupuku, ā, i muri mai ka pāngia e te mamae o te wheua, e te ngoikore rānei o ngā wheua. Tērā pea kua pāngia koe e tēnei āhuatanga. Ko te mea nui o tēnei ko te horapa o ngā pūtau mate pukupuku mai i tētahi wāhanga o te tinana ki ngā wheua. Ka kiia tēnei he metastasis wheua . Ahakoa he mate kino tēnei, kaua e mataku. Ko te mea nui ko te mōhio ki tēnei āhuatanga me te whakahaere tika.

He aha te Metastasis o te Wheua? Me mārama noa iho.

Ki te kī ngāwari, ko te horapa o te wheua ko te haere o ngā pūtau matepukupuku i tīmata mai i tētahi atu wāhi o tō tinana (pērā i te ū, te pūkahukahu, te repeure rānei) mā roto i ō toto ki ō wheua, ā, ka tīmata te tipu ki reira. Koinei tētahi o ngā tohu o te matepukupuku horapa .

Ko te mea nui kia mōhio koe, ehara tēnei i te matepukupuku wheua tuatahi. He matepukupuku tēnei kua horapa ki ngā wheua mai i tētahi atu wāhi.

Engari, kāore he rongoā mō tēnei mate. Heoi, he maha ngā maimoatanga e wātea ana hei whakahaere i ngā tohu me te whakaroa i te whanaketanga o te mate. Ko tētahi atu āhuatanga ko te roa ake o te oranga o te tangata me te mate pukupuku i tō mua, nō reira kei te piki haere te horapa o te wheua ki te wheua. I whakaatuhia e tētahi rangahau kua piki ake te maha o ngā horapa o te wheua mai i te 3% i te tau tuatahi i muri i te tātaritanga o te mate pukupuku ki te 8% i muri i te 10 tau.

He aha ngā tohu o tēnei? Tirohia mēnā kei a koe anō ēnei tohu?

Ko te tohu tino kitea ko te mamae o te wheua . Ka rite ki te mea e kumea ana tetahi mea, ki te taumaha rānei. Ka kino ake te mamae i te pō, inā koa i te pō. I ētahi wā ka koi, ka wero, ka koi rānei.

Ka pā mai pea ētahi atu raruraru ki te horapa o te wheua. Tērā atu anō ētahi tohu motuhake e pā ana ki tēnei:

• Ngā Whati Wheua: Mā tēnei āhuatanga ka tino pakarukaru ō wheua. Arā, ka taea e koe te whati i te wheua me te kore e hinga nui. Ka pā ki tētahi wheua o tō tinana. Engari ko te nuinga o te wā ka pā ki te tuaiwi, ki ngā rara, ki te hope, ki te humerus, ki te femur, me te angaanga. He tino koi, he tino kino te mamae ina whati te wheua. Ki te whati te ringa, te waewae rānei, e kore e taea e koe te neke.
• Hypercalcemia: Koinei te wā ka tino teitei rawa ngā taumata konupūmā o roto i tō toto. Ko ngā tohu ko te whanoke, te mate kōroke, te kore hiahia kai, te whakapairuaki, me te ruaki.
• Te Pēhanga o te Taura Tuaiwi: Mena kua horapa te pukupuku, ā, kei te pēhi i tō taura tuaiwi, tera pea ka pāngia koe e te mamae o te tuara, te ngoikore, te ngoikore rānei o ō ringaringa me ō waewae, me te kore e taea te pupuri i te mimi. Koinei te takeMe whakaaro he āhuatanga ohorere tēnei.

He aha tēnei e tupu nei? He aha te take?

Ka puta tēnei āhuatanga ina pakaru ngā pūtau mai i ngā pukupuku matepukupuku, ka tomo ki roto i tō toto, ka haere mā roto, kātahi ka haere ki ō wheua. Kia tae ki reira, ka tīmata aua pūtau matepukupuku i tētahi tukanga e kiia nei e ngā tohunga ko te "porowhita kino o te metastasis wheua."

Hei mārama ki tēnei huringa, he pai ki te mōhio ki te mahi a ō pūtau wheua. E rua ngā momo pūtau matua o roto i ō tātou wheua: ko ngā osteoblast me ngā osteoclasts .

• Ko ngā osteoblast he pūtau e hanga ana i te wheua hou.
• Ko ngā osteoclasts he pūtau e whakarewa ana, e wahi ana, e tango ana hoki i ngā pūtau wheua tawhito, kua pakaru.

I te nuinga o te wā, ka mahi tahi ēnei momo pūtau e rua ki te pupuri i te taurite i waenga i te hanga o ngā pūtau wheua hou me te whakakapinga o ngā pūtau wheua tawhito. Engari ina uru te mate pukupuku ki roto i ngā wheua, ka hē te tukanga nei. Anei ngā mea ka tupu:

• Ki te nui rawa ngā pūtau wheua hou e hangaia ana e ngā osteoblast , ka nui rawa te hanga o tō wheua, ā, ka puta he wāhi hanganga wheua rerekē i roto i a koe. Tērā pea ka tapaina ēnei wāhi e tō tākuta he whara osteosclerotic , he whara osteoblastic rānei. Ahakoa te āhua pakeke o ēnei wāhi mai i waho, he tino pakarukaru, pērā i te paparanga hukapapa angiangi i te taha o te awa. Ka taea e rātou te pakaru me te pakaru ngāwari.
• Ina tere ake te pakaru o ngā pūtau wheua e ngā osteoclast i te tikanga, ka taea e ngā matū e tukuna ana e ō pūtau wheua te hanga i ngā kōhao ririki ki roto i tō wheua. Ki te tirohia i raro i te karuārai, ka rite ki te mea kua keria e tetahi he kōhao ki roto i tō wheua. Ka kiia ēnei kōhao e tō tākuta he whara osteolytic . Ka pakarukaru, ka ngoikore hoki ō wheua i ēnei whara. Ka nui ake te tūponotanga o te whati o te wheua.

Kua whakaatuhia e ngā rangahau he hononga kei waenganui i ētahi momo pūtau wheua me ētahi momo mate pukupuku kua horapa. Hei tauira, 70% ki te 85% o ngā metastases wheua mai i te mate pukupuku prostate he osteogenic, arā, nā te nui rawa o te wheua e hangaia ana e ngā osteoblast. Heoi, 75% o ngā metastases mai i te mate pukupuku ū he osteolytic, arā, nā te tere rawa o te pakaru o ngā pūtau wheua.

Me pēhea koe e mōhio ai ki tēnei?

Ka whakahaerehia e tō tākuta ētahi whakamātautau whakaahua hei tātaritanga i tēnei mate. Tērā pea ka whakahaerehia hoki e rātou he whakamātautau toto , he whakamātautau mimi rānei hei rapu i ngā matū e tohu ana i te pakaru o te wheua. Tērā pea ko ngā whakamātautau whakaahua ko:

• Matawai wheua
• Matawai CT (Tomography rorohiko - Matawai CT)
• Matawai MRI (Whakaahua aukume - matawai MRI)
• Matawai PET (Positron emission tomography - matawai PET)
• X-ray

Ka taea e ēnei whakamātautau te whakatau tika i te āhua o ō wheua, mēnā kua horapa ngā pūtau matepukupuku, me te tawhiti kua horapa.

He aha ngā maimoatanga?

Engari, kāore he rongoā mō te horapa o te wheua ki roto i te tinana. Heoi anō, kei reira ngā rongoā me ngā maimoatanga hei āwhina i te whakaiti i te mamae me te whakahaere i te haere whakamua o te mate . Ka taea e ēnei maimoatanga te whakapai ake i te kounga o tō oranga.

Anei ētahi o ngā tikanga maimoatanga matua:

• Ngā Bisphosphonates: Ka whakapakari ēnei rongoā (hei tauira, Pamidronate, Zoledronic acid (Zometa®)) i ō wheua, ka whakaiti i te nui o te konupūmā i roto i ō toto, ā, ka whakaiti i te tūponotanga o te whakawhanake i te hypercalcemia.
• Te rongoā matū, te rongoā homoni rānei: Ka tohua pea tēnei maimoatanga e tō tākuta mēnā he maha atu i te kotahi ngā wāhi e horapa ana ngā pūtau matepukupuku (metastases) ki ō wheua.
• Te rongoā paturopi monoclonal: Ka hoatu ngā rongoā pēnei i te Denosumab (Prolia®, Xgeva® rānei) hei whakaiti i te mōrearea o te whati wheua.
• Whakaora irahiko: Mena kei te mamae koe i te pukupuku i roto i tētahi o ō wheua, ka hoatu pea te rongoā irahiko hei rongoā i taua mamae. Ka taea hoki e ia te āwhina i te mamae i puta mai i te pēhanga o te taurakira. Ka hoatu pea e tō tākuta he corticosteroids ki a koe me te rongoā irahiko.
• Kyphoplasty: He maimoatanga tēnei mō ngā whati pēhanga tuaiwi.
• Pokanga: Ka tūtohu pea tō tākuta kia pokangahia hei whakapakari i ngā wheua pakarukaru, hei tango rānei i te pukupuku matepukupuku.

Kia maumahara, mā tō tākuta e whakatau te maimoatanga pai rawa atu māu, nō reira me kōrero marie ki a ia mō tēnei mea.

Ka aha mēnā ka kore e rongoatia?

Ki te kore e rongoatia te horapa o te wheua ki roto i te tinana, ka puta pea ngā raruraru pēnei i te hypercalcemia. Ki te kore e rongoatia, ka arahi pea tēnei ki te koma. Waihoki, kāore pea koe e taea te hikoi, te mahi rānei i tāu mahi nā te whati o te wheua. Ka taea e te mamae nui o te wheua te whakaiti i tō kaha ki te pārekareka ki te ora. Ko te mea nui, ko te pēhanga o te taurakira ka arahi pea ki te pararutiki ki te kore e rongoatia. Nō reira, kaua e warewarehia ngā tohu.

He aha ngā mea hei tumanako atu mēnā kua horapa te wheua ki roto i a koe?

Mena kua horapa te mate pukupuku ki te wheua, ko te tikanga kua horapa te mate pukupuku mai i tētahi atu wāhanga o tō tinana ki ō wheua. He tohu tēnei mō te mate pukupuku kua horapa haere . I tēnei wā, me whiwhi koe i te maimoatanga hauora me te tautoko mō te mate pukupuku tuatahi me te mate pukupuku kua horapa ki te wheua.

He mea tino nui kia kaua e mataku, kia whai i ngā tohutohu a te taote, kia noho pai hoki.

Kia pēhea te roa ka taea e koe te ora me tēnei mate?

He uaua ki te hoatu i tētahi whakautu kotahi ki tēnei pātai. Nā te mea he maha ngā āhuatanga e whakawhirinaki ana ki tēnei. Ka rerekē pea tēnei wā, mai i te ono marama ki te neke atu i te whā tau. Ko ngā āhuatanga matua e pā ana ki tēnei:

• Momo matepukupuku: E ai ki tētahi rangahau, ko te wā ora mō te matepukupuku pūkahukahu kua horapa ki ngā wheua e ono ki te whitu marama te roa, mō te matepukupuku repeure kua horapa ki ngā wheua ia, e 53 marama te roa.
• Te Wāhanga o te Matepukupuku: Ko te hunga e pāngia ana e te matepukupuku i te Wāhanga I (Wāhanga I) he iti ake te tūponotanga ka pāngia e te matepukupuku i te wheua i te hunga i pāngia i te Wāhanga IV (Wāhanga IV). Hei tauira, i kitea e ngā kairangahau i whai i te tere o te pāngia e te wheua i te 10 tau i muri i te tātaritanga o te matepukupuku, 3% o te hunga e pāngia ana e te Wāhanga I i pāngia e te mate, ko te 28% o te hunga e pāngia ana e te Wāhanga IV i pāngia e te mate.

He mate pukupuku wāhanga 1 tōku, ā, kua tīmata te memeha haere. He aha i horapa ai taku mate pukupuku?

Engari, i ētahi wā ahakoa kua rongoatia te mate pukupuku, ā, kua memeha haere , ka taea tonu te puta o te mate pukupuku kua horapa, e mōhiotia ana ko te metastasis wheua. Ko te tikanga o te "whakakorenga" kāore he tohu, ā, kāore he tohu o te mate pukupuku e kitea ana i roto i ngā whakamātautau. Mena kua horapa ō wheua, ka kī pea tō tākuta he mate pukupuku tawhiti e hoki mai ana tēnei āhuatanga. Ko te mate pukupuku e hoki mai ana ko te hokinga mai o te mate pukupuku i muri i te maimoatanga.

Me pēhea taku tiaki i ahau anō?

Ka pāngia tō kounga o te oranga e te horapa o te wheua. Ehara i te mea ngāwari te noho me ngā tohu pēnei i te mamae me te whakaaro kei te horapa te mate pukupuku. Engari anei ētahi whakaaro hei āwhina i a koe:

• Kai pai: Ka pāngia tō hiahia kai e ngā raruraru o te horapa o te wheua. Kōrero ki tētahi tohunga kai hei whakawhanake i tētahi mahere kai hauora e pai ana māu.
• Whakaarohia ngā kaupapa whakaora i te mate pukupuku: He tangata ora koe i te mate pukupuku mai i te rā i kitea ai tō mate. Nā te mea kei te pāngia koe e te mate wheua kua horapa, he rite tonu koe. Tērā pea he kaupapa me ngā rōpū tautoko hei āwhina i te hunga kei roto i te āhuatanga kotahi me koe.
• Pātai atu mō te tiaki mamae:He maha ngā wā, ko te tohu tuatahi o te horapa o te wheua ko te mamae o te wheua. Ka taea e tēnei mamae te kino, ā, ka pā ki tō kounga o te oranga. Kei roto i te tiaki mamae ngā rongoā mamae me ētahi atu tautoko whakahaere mamae. Kei roto hoki i te tiaki mamae te tohutohu hinengaro hei āwhina i a koe ki te whakahaere i ngā wero kare ā-roto e pā ana ki te mate pukupuku mutunga kore.
• Tirohia ngā whakamātautau haumanu: Kei te rapu ngā kairangahau i ngā huarahi hou hei rongoā i ngā mate wheua kua horapa mai i ngā momo mate pukupuku. Pātai atu ki tō tākuta mō ngā whakamātautau haumanu e tika ana māu.

Me whakaaro ahau ki te tiaki hōhipera?

Kei tō āhua te āhua. Mena kei te whakaaro tō tākuta kāore pea tō mate pukupuku e ora mā te haere tonu o te maimoatanga, ā, e ono marama, iti iho rānei tō oranga mēnā ka mutu te maimoatanga, ka tūtohu pea ia i te tiaki hōhipera . Ko te arotahi a te tiaki hōhipera ko te whakamarie tinana, te kore mamae, me te whakahaere i ētahi atu tohu.

Āhea ahau me toro atu ki taku tākuta?

Mena kei te kino haere ō tohumate o te horapa o te wheua, hei tauira, ki te mamae koe kāore e taea te whakahaere ahakoa he rongoā kua tohua, me toro atu ki tō tākuta tonu. Kia maumahara, kāore koe e hiahia ki te noho me te mamae nui o te horapa o te wheua. Ka tohua e tō tākuta he rongoā whakamamae mamae me ētahi atu maimoatanga kāore e pā ki tō kounga o te oranga, tae atu ki tō kaha ki te noho tahi me ō whanaunga.

Āhea ahau me haere ki te Rūma Ohotata?

Mena kei a koe ngā tohu o te pēhanga o te taurakira, me waea atu koe ki te 911, me haere rānei ki te rūma whawhati tata tonu. Ko ēnei tohu ko:

• Mena ka māuiui, ka ngoikore rānei ō waewae, ō kapu waewae, tō puku raro rānei.
• Mena he uaua ki te neke i ō waewae.
• Ki te kore e taea e koe te whakahaere i tō mimi, i tō tūtae rānei.
• Ki te kore rawa e taea e koe te mimi.

Ki te kore e rongoatia, ka taea e te pēhanga o te taurakira te arahi ki te pararutiki, no reira kia tino tūpato ki ēnei tohu.

He aha ngā pātai me pātai atu e au ki taku tākuta?

Mā te mōhio kua horapa te wheua ki roto i a koe, i te mea kei te pāngia koe e te mate pukupuku, ka pā kino atu ki te kounga o tō oranga. Anei ētahi pātai ka taea e koe te pātai atu ki tō tākuta:

• Ko ēhea o aku wheua kua kī tonu i ngā pūtau matepukupuku?
• He aha te pānga o te mate pukupuku wheua ki taku āhua whānui?
• He aha ngā maimoatanga, ngā huinga maimoatanga rānei ka taea te āwhina i ahau?
• Ka taea e ngā maimoatanga te aukati i te horapa o ngā pūtau wheua ki ētahi atu wheua?
• He aha ngā kōwhiringa hei whakahaere i te mamae o tōku wheua?
• Me pēhea te whakaiti i te mōrearea o te whati wheua?

He aha te rerekētanga i waenga i te Matepukupuku Wheua me te Metastasis Wheua?

He mea tēnei e whakapoauau ana i te tini o te tangata.

• Ko te mate pukupuku wheua he momo mate pukupuku e tīmata ana i roto i ō wheua, pērā i te osteosarcoma , te Ewing sarcoma rānei.
• Ko te horapa o te mate pukupuku ki te wheua ko te wā i tīmata ai te mate pukupuku i tētahi atu wāhi o tō tinana i muri mai ka horapa ki ō wheua.

He tohu te horapa o te wheua ki te mate pukupuku. Tērā pea ka kīia atu ki a koe kei te horapa tō wheua, ko te wā tuatahi tēnei ka mōhio koe kua horapa tō mate pukupuku mai i tōna tīmatanga. Tērā pea ka nui rawa te mamae me te pouri o ngā rongo. Heoi anō, ko te mōhio kei te puta te mamae tonu i te wheua, ā, ka pā ki tō kounga o te oranga, ka nui ake te pouri. Tērā pea ka āwangawanga koe, ka mataku hoki mō ngā mea ka tūpono i muri mai. Engari kia mahara, kei reira ō tākuta hei whakarongo ki a koe, hei mārama hoki ki ō āwangawanga. Ka taea e rātou te āwhina i a koe ki ngā mea katoa mai i te whakahaere i tō mamae ki te whakamārama i ngā mea ka tūpono mēnā ka horapa tō mate pukupuku.

Hei whakamutunga, he karere hei kawe ki te kāinga:

Ahakoa he mate kino te horapa o te wheua ki roto i te wheua, he huarahi hei whakahaere i tēnei.

• Ko te mea nui kia kaua e mataku, kia ata whai hoki i ngā tohutohu a te tākuta.
• He maimoatanga kei reira hei whakahaere i te mamae, hei pupuri hoki i te kounga pai o te oranga.
• Kāore koe i te mokemoke. Kei a koe te whānau, ngā hoa, ngā tākuta, me ngā tohunga hauora hei āwhina i a koe.
• He mea tino nui te noho pai me te kaha o te hinengaro i tēnei haerenga.

Mena he pātai anō āu mō tēnei, kaua e wehi ki te pātai atu ki tō tākuta. Māna e whakamārama ngā mea katoa ki a koe.

Matepukupuku , horapa o te wheua, mamae wheua, horapa o te matepukupuku, maimoatanga matepukupuku, pikinga o te konupūmā, pēhanga tuaiwi