Kia ako tātou mō ngā mate tauhou e haere tahi ana me te mate pukupuku (Paraneoplastic Syndromes)!

Kua rongo kē koe mō tētahi tangata e pāngia ana e te mate pukupuku e pāngia ana e ngā tohu kāore i puta mai i te mate pukupuku tonu, engari nā ētahi atu mate? He rite tonu ki te mea kei roto te mate pukupuku i tētahi wāhanga o te tinana, engari kei te horapa ōna pānga ki ētahi atu wāhanga. Koinei te mea e kiia nei e tātou ko (Paraneoplastic Syndromes) . Tērā pea he ahua uaua tēnei, engari me kōrero tātou mō te āhua o te mate. Kaua e mataku, he mea tino nui kia mōhio ki tēnei.

He aha te mate paraneoplastic?

Ki te kī ngāwari, ina pāngia koe e te mate pukupuku, ka kiia e mātou he Paraneoplastic Syndrome , arā, ko te putanga mai o ētahi atu tohu i roto i te tinana, ehara i te mea nā ngā pūtau mate pukupuku i puta tika mai. Whakaarohia, he mate pukupuku kei roto i te tinana, engari ko ētahi homoni , ko ngā pūmua rānei i tukuna e ia ka meinga he pūnaha motuhake i roto i te tinana kia tīmata te mahi rerekē. I ētahi wā rānei, i a tā tātou pūnaha ārai mate , e ngana ana ki te whakangaro i ngā pūtau mate pukupuku, ka whakaeke hē i ngā pūtau pai. Ka kiia e mātou tēnei he urupare ā-tinana . Ka puta anō hoki ēnei tohu i roto i ēnei āhuatanga.

Ka pāngia pea ngā pūnaha rerekē o te tinana e ngā mate paraneoplastic . Hei tauira, ka pāngia tō pūnaha io , te pūnaha endocrine (te pūnaha e hanga ana i ngā homoni), ngā whatukuhu , ngā wheua , ngā hononga , te kiri, me te toto .

He maha ngā wā, ko ngā tohu o tētahi o ēnei (Paraneoplastic Syndromes) ngā tohu tuatahi o te mate pukupuku. Nō reira, he mea tino nui kia mōhio koe ki tēnei.

Ko wai te mea ka tino pāngia e tēnei mate? (Ko wai ka pāngia e ngā mate paraneoplastic?)

He nui ake te kitea o ngā mate paraneoplastic i roto i te hunga pakeke me te hunga kaumātua, inā koa ko te hunga he mate pēnei i te mate pukupuku pūkahukahu , te mate pukupuku lymphatic , te mate pukupuku ovarian , te mate pukupuku ū rānei. Ko ngā āhuatanga e hua ai te mate pukupuku ka taea hoki te hua o ēnei mate.

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He pēhea te noa o ēnei? (He pēhea te noa o ngā mate paraneoplastic?)

E 8% ki te 20% o te hunga whai matepukupuku ka pāngia e ngā matepukupuku paraneoplastic . Ko te tikanga, ehara i te katoa o ngā tūroro matepukupuku ka pāngia e ēnei matepukupuku, engari he nui te hunga ka pāngia.

He aha ngā mate pukupuku e hono ana ki ngā mate paraneoplastic?

Te tangata whai pukupuku matepukupuku (Paraneoplastic Syndrome)Ahakoa ka pā mai tētahi ki tētahi, he maha ngā momo mate pukupuku e hono pinepine ana ki ēnei āhuatanga:

• Matepukupuku ū
• Matepukupuku puku
• Leukemia
• Lymphoma
• Te mate pukupuku pūkahukahu (ina koa ko te mate pukupuku pūkahukahu pūtau-iti)
• Matepukupuku ovarian
• Matepukupuku repeure
• Matepukupuku prostate
• Matepukupuku whatukuhu
• Matepukupuku o te kōpū

He aha ngā take o ngā mate paraneoplastic?

Kua kōrero kē tātou e rua ngā take matua mō tēnei.

1. Ngā matū e tukuna ana e ngā pūtau matepukupuku: Ka tukuna e ētahi matepukupuku ngā homoni me ngā pūmua . Mā ēnei matū ka kore e mahi tika ētahi okana o te tinana. Ki te kore e rongoatia, ka pā he kino tuturu.

2. Te hē o te pūnaha ārai mate: Kei reira te pūnaha ārai mate o tō tātou tinana hei tiaki i a tātou mai i ngā mate. Ka whakaputahia e tēnei pūnaha ngā matū e kiia nei ko ngā paturopi . Ka kitea, ka whakangaromia hoki e ēnei paturopi ngā pūtau rerekē, pērā i ngā pūtau matepukupuku. Engari i ētahi wā, ka ranea ēnei tohu, ā, ka tīmata ngā paturopi ki te whakaeke i ngā pūtau hauora. Koinei te wā ka puta mai ai ngā tohu o te (Paraneoplastic Syndrome) .

He aha ngā tohu o ngā mate paraneoplastic?

Ka rerekē pea ngā tohu e puta mai ana i tēnei i ia tangata, i ia tangata. Kei te pūnaha o te tinana e pāngia ana. He mea whakamiharo, neke atu i te 60% o ngā take, ka puta ngā tohu o tēnei mate i mua i te tautuhi i te mate pukupuku. Nō reira, ki te kitea wawetia ēnei tohu, ka taea te kite i te mate pukupuku me te rongoā i te wā tōmua. Kātahi ka nui ake te tūponotanga o te angitu o te maimoatanga.

Ngā tohu noa

Koinei ētahi o ngā tohu tino kitea:

• Kirika
• Te ngaronga o te hiahia kai me te mate taimaha
• Te werawera o te pō

Ina pāngia te pūnaha io

Mena ka pāngia tō pūnaha io matua (arā, tō roro me tō tuaiwi) me te pūnaha io taha (ngā io e puta ana i te roro me te tuaiwi), ka pāngia pea koe e ngā tohu pēnei i:

• Pōuriuri
• Tirohanga takirua
• Te uaua ki te kōrero
• Ngaronga o te mahara
• Ngā mate haurangi ( ngā hopukanga )
• ngoikore o te uaua
• Te whakaiti i ngā urupare, ngā kare ā-roto, ngā mahi tahi rānei
• Te ngaronga o te rongo i roto i ō ringaringa me ō waewae

Whakaarohia, he mate pukupuku pūkahukahu tō tetahi, engari ka tīmata ohorere te ngaro o tōna mahara, te koretake o āna kupu ina kōrero, ā, ka uaua ki te pupuri i tōna taurite ina hikoi. Koinā te wā e whakapae ana ngā tākuta he mate pukupuku (Paraneoplastic Syndrome) tēnei.

Ina pāngia te pūnaha endocrine

Mena ka pāngia tō pūnaha homoni, ka pāngia pea koe e ngā tohu penei:

• Ngenge rawa
• toto toto tiketike
• ngoikore o te uaua
• Whakapairuaki me te ruaki
• Te pikinga taumaha ohorere me te kore he take

Ina pāngia ngā hononga, ngā wheua me ngā uaua (Ngā hononga, ngā wheua me ngā uaua - rheumatologic)

Mena ka pāngia ēnei pūnaha:

• Ngā āhuatanga pēnei i te rumatiki
• Te mamae o ngā hononga, te pupuhi, te pakari rānei

Ina pā ki te kiri )

I ētahi wā ka pāngia te kiri:

• Te mākūkū
• Te horoi
• Kiri matotoru
• Ngā tipu kiri pai (kore-matepukupuku)

He aha ngā momo mate paraneoplastic?

He maha ngā momo Paraneoplastic Syndromes . Ka whakarōpūtia ēnei i runga i te pānga ki ia pūnaha.

Ngā mate paraneoplastic o te pūnaha io

Ētahi tauira:

• (Te pirau o te roro iti): He kino tēnei ki te roro iti, ka pā ki ngā mea pēnei i te taurite me te hikoi.
• Dysautonomia: Ka pā ki te mahi a te pūnaha io motuhake.
• Te mate pukupuku roro (encephalitis): Te mumura o te roro.
• Encephalomyelitis: Te mumura o te roro me te taurakira.
• Te mate myasthenic Lambert-Eaton (LEMS): Ka ngoikore te uaua.
• Myasthenia gravis (MG): Ko tētahi atu āhuatanga tēnei e ngoikore ai ngā uaua.
• Myelopathy: Ngā mate e pā ana ki te taurakira.
• Neuromyotonia: Te ngohe tonu o ngā uaua.
• (Opsoclonus-myoclonus syndrome): Ngā nekehanga rerekē o ngā kanohi me ngā uaua.
• (Neuropathy peripheral): Te kino ki ngā io peripheral.
• (Stiff-person syndrome): Te pakari o ngā uaua me ngā mamae o te ngākau.

Ngā mate paraneoplastic o te pūnaha endocrine

Ngā tauira:

• (Te mate a Cushing): He mate e hua mai ana i te pikinga o te homoni cortisol.
• Hypercalcemia: Te pikinga o ngā taumata konupūmā i roto i te toto.
• (Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH): He āhuatanga e piki ai te pupuri wai i roto i te tinana.

Ngā mate paraneoplastic rūmātiki

(ka pā ki ngā hononga, ngā wheua, ngā uaua me ngā kiko honohono)

Ngā tauira:

• (Te mate pāwera eosinophilic)
• (Erythromelalgia)
• (Te mate wheua hypertrophic)
• (Te mate pāwera o te nikau)
• (Te mate pūkahukahu paraneoplastic)

Ngā mate paraneoplastic toto

Ngā tauira:

• (Paraneoplastic erythrocytosis): Te pikinga o ngā toto whero.
• (Paraneoplastic thrombocytosis): Te pikinga o ngā pereti toto.

Ngā mate kiri paraneoplastic

Ngā tauira:

• Acanthosis nigricans: He kiri mātotoru, he pouri ngā wāhi.
• Dermatomyositis: Te mumura o te kiri me ngā uaua.
• Leukocytoclastic vasculitis: Te mumura o ngā oko toto iti.
• (Paraneoplastic pemphigus): He āhuatanga e puta ai te pupuhi o te kiri.
• (Sweet syndrome): Te kirika me ngā whara kiri mamae.

Ngā mate paraneoplastic whatukuhu

Ko te paraneoplastic glomerulonephritis he mate e pā ana ki ngā whatukuhu.

Me pēhea te tautuhi i ngā mate paraneoplastic?

Ka tātaritatia tēnei mate e tō tākuta mā te pātai atu ki a koe mō tō hītori hauora, te whakahaere i tētahi whakamātautau tinana, me te whakahaere i ētahi atu whakamātautau.

• Whakamātautau io: Nā te mea he maha ngā wā ka pāngia te pūnaha io e tēnei mate, ka tono tō tākuta kia mahi koe i ētahi mea hei tirotiro i te mahi a tō roro me ō uaua. Ka tirohia e rātou ngā huringa o tō kaha, tō mahara, me tō taunga.
• Ngā whakamātautau whakaahua: Ka taea te whakamahi i ngā whakamātautau pēnei i te CT scan , te MRI , me te ultrasound hei tirotiro mēnā he pukupuku kei te pūtake o ngā tohu.
• Ngā whakamātautau toto: Ka taea e ngā whakamātautau toto te whakaatu i ngā mea ka ara ake ai te whakapae mō te mate pukupuku. Ka taea hoki e rātou te tirotiro mō ngā paturopi e pā ana ki ngā mate paraneoplastic . Ka taea hoki e ēnei whakamātautau te whakatau mēnā i puta mai ngā tohu i ētahi atu take, pērā i ngā mate pāwera, i ngā kore taurite o ngā homoni rānei.
• Te pokanga tuaiwi / te weronga hope: I ētahi wā, ka whakamatautauria tō wai cerebrospinal (CSF) kia kitea ai mēnā he paturopi e whakaeke ana i ngā pūtau hauora. Ko te tikanga o tēnei ko te wero i tētahi ngira iti ki roto i tō tuara o raro , kātahi ka tangohia he tauira o te wai. Kātahi ka tirohia.

Me pēhea te whakahaere, te rongoā rānei i ēnei āhuatanga? (Me pēhea te whakahaere, te rongoā rānei i ngā mate paraneoplastic?)

Ko te mea nui ko te rongoā i te mate pukupuku e puta ai ō tohumate. I taua wā anō, ka whakahaerea hoki e koe ō tohumate hei whakaiti i te kino ki ngā okana, ki ngā pūnaha rānei o tō tinana.

Ko ētahi o ngā maimoatanga e whakamahia ana hei whakahaere i ngā mate paraneoplastic :

• Ngā corticosteroids:Ngā rongoā pēnei i te (Cortisone) me te (prednisone). Mā ēnei ka whakaiti i te mumura (pupuhi) i roto i te tinana.
• Te Pehi i te Ārai Mate: Ngā rongoā hei whakaiti i te urupare a te pūnaha ārai mate o tō tinana. Ka tohua e tō tākuta ngā rongoā i runga i te momo paraneoplastic syndrome kei a koe.
• Immunoglobulin intravenous (IVIG): Ka mahi tēnei maimoatanga mā te whakangaro i ngā paturopi kino. I roto i tēnei, ka tukuna ngā paturopi hauora hei werohanga, hei whakangaro i ngā paturopi kino.
• Plasmapheresis: Ko te tango i te plasma (te wāhanga wai o te toto) i te toto hei whakaiti i te nui o ngā paturopi kei roto i tēnei plasma, ā, ka taea te kino i ngā kiko hauora.
• Te whakaora tinana me te whakaora kōrero: Kei roto i tēnei ko ngā mahi whakakorikori uaua hei whakapai ake i ngā mahi pēnei i te kōrero me te nekeneke. Tērā pea ka hiahiatia tēnei maimoatanga mēnā he mate paraneoplastic tōu e pā ana ki te pūnaha io.

He aha taku e tumanako atu ai mēnā he mate paraneoplastic tōku?

Ko te āhua o tō mate pukupuku e whakawhirinaki ana ki te taumata o tō mate pukupuku. I ētahi wā, he ngawari, he rangitahi rānei ngā tohu e puta mai ana i tēnei mate. I ētahi atu wā, he kino pea ngā tohu, ā, me whakahaere mō te wā roa.

Kōrero ki tō tākuta mō te pānga o te taumata o tō matepukupuku me tō urupare ki te maimoatanga ki tō whakaoranga.

He aha ngā raruraru e pā ana ki ngā mate paraneoplastic?

Ka taea e tēnei te arahi ki ngā momo raruraru. Ko ētahi he iti noa iho, ko ētahi he kino rawa atu, ā, ka mate pea mēnā kāore e rongoatia. Ma tō tākuta koe e whakamārama ki a koe i ngā raruraru me ngā kōwhiringa maimoatanga.

Āhea ahau me waea atu ki te tākuta mō ngā mate paraneoplastic?

Ki te puta mai ngā tohu o te mate paraneoplastic kāore he take mārama, me toro atu ki te tākuta. Ina koa kua rongoatia koe mō te mate pukupuku i roto i ngā tau e rima kua pahure ake nei , ā, kei te pāngia koe e ēnei tohu, he mea pai kia whakamātauria anō koe. Mā tēnei hoki ka āwhina i tō tākuta ki te whakatau mēnā kua hoki mai anō te mate pukupuku.

He aha ngā pātai me pātai atu e au ki taku tākuta?

Ko ētahi pātai ka taea e koe te pātai atu ki tō tākuta:

• He aha te take o aku tohumate?
• He aha te pānga o taku (Paraneoplastic Syndrome) ki taku mahere maimoatanga matepukupuku?
• He aha ngā kōwhiringa maimoatanga kei a au?
• TakuHe aha te pānga o te Paraneoplastic Syndrome ki taku whakaoranga?
• Ka pai ake aku tohu i muri i te maimoatanga matepukupuku?
• Me pēhea te whakahaere i ngā tohu mō te wā poto? Me pēhea te whakahaere i ngā tohu mō te wā roa?

Hei whakamutunga, he karere hei kawe ki te kāinga

Ka taea e ngā pukupuku matepukupuku te whakaputa i ngā huringa ohorere i roto i te tinana. I ētahi wā, ka uru atu hoki ki roto ngā tohu o te mate paraneoplastic . Nā te mea he maha ngā momo o ēnei matepukupuku, ā, he rerekē ngā tohu, ka roa pea te wā ka mōhio tō tākuta he hononga ō tohu ki te matepukupuku. Heoi, ina whakaūtia te tātaritanga, ka taea e ia te rongoā i ngā tohu, me te mea nui, te matepukupuku taketake .

Ko te huarahi pai ki te whakahaere i te Paraneoplastic Syndrome ko te whiwhi i te maimoatanga tino whai hua mō te mate pukupuku. Nō reira, kaua e warewarehia ngā tohumate katoa. Mena he ruarua āu, tirohia te tākuta i te wā e taea ai. Ko reira anake ka taea ai e tātou katoa te noho hauora.

Ngā mate paraneoplastic, mate pukupuku, ngā tohu, te pūnaha io, te pūnaha endocrine, te pūnaha ārai mate, te maimoatanga mate pukupuku