Kei a koe te Peripheral T-cell Lymphoma (PTCL) ? Kaua e manukanuka, me kōrero tāua!

I ētahi wā, ka pāngia tātou e ngā mate kāore i te whakaarohia e tātou, tika? He āhua uaua te Peripheral T-cell Lymphoma, arā, te PTCL , engari he mea nui kia mōhio ki tēnei mate. Ehara i te mate kotahi, engari he huinga o ngā mate maha. Me kōrero noa tātou mō tēnei mea, i roto i te huarahi e mārama ai koe?

Ehara te Peripheral T-cell Lymphoma (PTCL) i te mate kotahi. He rōpū o ngā momo matepukupuku toto kaha . Ina koa, ka pā ki tō tātou pūnaha lymphatic . Kua rongo pea koe i tēnei ingoa ko te "Non-Hodgkin lymphoma", ā, koia tonu. Ko tētahi āhuatanga o te PTCL ko tōna horapa (metastasize) mai i tētahi wāhanga o te tinana ki ētahi atu wāhanga . Ko te tikanga ka pā ki te nuinga o ngā wāhanga o te tinana, nō reira ka rerekē ngā tohu.

Ko te rongo pai, ka taea e ngā tākuta te whakahaere angitu i ngā momo PTCL maha. Heoi, i ētahi wā ka hoki anō te mate. Koia te take e rapu tonu ai ngā kairangahau hauora i ngā maimoatanga hou hei āwhina i te tangata kia roa ake te ora me te PTCL.

He mate noa te PTCL?

Kāo, ehara tēnei i te mate tino noa . E whakaatu ana tētahi rangahau puta noa i te ao e rua rau mano ngā tāngata e pāngia ana e te PTCL. Tata ki te 10% o te hunga e pāngia ana e te (Non-Hodgkin lymphoma) he PTCL tō rātou.

He nui ake te kitea o tēnei mate i roto i ngā whenua Āhia, Āwherika, me te Karipiana i tērā i te Hononga o Amerika. He maha tonu te pānga ki te hunga neke atu i te 60 tau te pakeke . Heoi, ka taea hoki e ētahi momo te pā ki ngā tamariki nohinohi me ngā taiohi .

He aha ngā momo matua o te PTCL?

Neke atu i te 20 ngā momo PTCL kua tautuhia e te Whakahaere Hauora o te Ao (WHO). He tohu ira motuhake tō ia momo. Me titiro tātou ki ētahi o ngā momo tino noa.

Te lymphoma pūtau-T ā-rohe, kāore i te tohua i tētahi atu huarahi (PTCL-NOS)

Koinei te momo momo tino noa . Ko te (PTCL-NOS) he kāwai e whakauru ana i ngā kēhi kāore e taea te tautuhi tika, ā, kāore e uru ki roto i ngā momo momo momo mārama kē atu. Tata ki te 30% o ngā tūroro PTCL katoa ka taka ki tēnei kāwai. Ka pā pea ki ō pona lymph, te hinu wheua , te whēkau , te ate rānei.

Te mate pukupuku pūtau-T angioimmunoblastic (AITL)

Ka pā anō hoki tēnei ki te 15% ki te 30% o ngā tūroro PTCL puta noa i te ao. Ka pā anō hoki te AITL ki tō whēkau, ki tō hinu wheua, ki tō whēkau, ki tō ate rānei.

Te lymphoma pūtau nui anaplastic (ALCL)

He rerekē anō hoki ngā momo o te (ALCL).

• Kotahi te mea e kiia nei ko te ALCL kiri tuatahi , e pā ana ki te kiri .
• Kotahi anō.Ko te ALCL pūnaha, e pā ana ki ngā pukahukahu, te kiri, me ētahi atu okana. I ētahi wā ka whakarōpūhia anō tēnei ALCL pūnaha i runga i ngā huringa o tētahi ira motuhake e kiia nei ko te ALK (anaplastic lymphoma kinase) . Tata ki te 15% o te PTCL ka taka ki tēnei momo "(ALCL)".

Te lymphoma kaikōhuru taiao extranodal/pūtau-T, momo ihu

He āhua motuhake tēnei. Ko te nuinga o te wā ka puta tēnei momo i roto i ngā kiko o tō ihu , ngā kōhao sinus , me te korokoro o runga . Engari i ētahi wā ka horapa ki te kiri, ki te ara nakunaku , me ētahi atu okana. Tata ki te 10% o te PTCL te take o tēnei momo.

Ngā lymphoma pūtau-T o te puku

E kī ana te ingoa, tika? Ka pā tēnei ki te pūnaha nakunaku . E 6% pea o te PTCL. Kei roto hoki i tēnei ngā momo e kiia nei ko te enteropathy-associated T-cell lymphoma (EATL) me te monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL) .

Te mate pukupuku pūtau-T pakeke/te mate toto toto (ATLL)

Ka pā pea ki te kiri me ngā wheua. E whā ngā momo ATLL: te mate koi, te mate pukupuku, te mate mau tonu, me te mate paoa . Ko ngā momo e rua e tino kitea ana ko te mate koi me te mate pukupuku, he kaha te tipu. Ko ngā momo mau tonu me te mate paoa he puhoi ake te tipu . Ka pā ia momo ATLL ki ngā wāhanga rerekē o te tinana.

He aha ngā tohu o te PTCL?

Ahakoa he tohu motuhake kei ia momo PTCL, kei reira ētahi tohu noa. Me titiro tātou ki ēnei:

• Ngā pona waikura pupuhi: Tērā pea ka pupuhi tō kaki, ō ringaringa, ō hope rānei, engari kāore he mamae . Whakaarohia he puku iti i roto i tō kaki e ahua nui haere ana i roto i te wā, engari kāore e mamae. Koinā anake.
• Te whakahekenga taumaha kāore i te mārama: Ki te ngaro te 10% o tō taumaha katoa i roto i ngā marama e ono, me te kore e whakapau kaha, he mea tēnei hei āwangawanga māu.
• Mamae puku, pupuhi rānei: Ka pā tēnei mēnā kua rahi tō whēkau. Tērā pea ka kore e pai tō āhua, me te mea kua kī tonu tō puku.
• Ngenge tonu: Te ngenge nui mō ētahi rā, kāore he take e kitea ana. Me te mea nei kāore te ngenge e memeha ahakoa te roa o te moe.
• Te kirika kore whakamārama: I te nuinga o te wā, ka puta te kirika i te wā e whawhai ana te tinana ki tētahi mate. Heoi, ki te roa te kirika neke atu i te 39.5 nekehanga Celsius (103 Fahrenheit) mō ngā haora neke atu i te rua i muri i te maimoatanga kāinga, ki te roa rānei te kirika mō ngā rā neke atu i te rua, he tohu pea tēnei mō tētahi mea kino ake.

Ko te mea nui, kaua e manukanuka kei te pāngia koe e te PTCL nā te mea kei a koe ēnei tohu. Tērā pea he take māmā ake. Engari ki te mau tonu ēnei tohu,He mea tino nui kia kite i te tākuta me te tiki tohutohu.

Nā, kia titiro tātou he aha ngā tohu e puta mai ana me ētahi momo motuhake.

Ngā āhuatanga tāpiri o te lymphoma pūtau-T ā-peripheral, kāore i tohua i tētahi atu huarahi (PTCL-NOS)

Haunga ngā tohu noa, ka kitea pea e koe:

• Te hekenga o ngā toto whero (Anemia) - Ka pā te kiri mā me te ngenge nui.
• Te iti o te maha o ngā pereti toto (Thrombocytopenia) - Ka taea e tēnei te arahi ki te whakaheke toto.
• Ngā ira whero mākūkū i runga i te kiri.
• Mena kei roto i te uma te mate pukupuku , ka mamae te uma, ka uaua rānei te manawa (dyspnea).

Ngā āhuatanga tāpiri o te lymphoma pūtau-T angioimmunoblastic (AITL)

Hei tāpiri atu ki ngā tohu noa:

• Te werawera i te pō - Te nui o te werawera i a koe e moe ana, ā, ka mākū ngā whāriki o te moenga.
• Te kiri mākūkū.
• Ngā mate pūnaha ārai mate pērā i te "anemia hemolytic pūnaha ārai mate" .

Ngā āhuatanga tāpiri o te lymphoma pūtau nui anaplastic (ALCL)

ALCL kiri tuatahi (te momo e pā ana ki te kiri)

• Ngā mea pēnei i te whero rerekē, te parauri-whero rānei o te kiri, me ngā puku ka nui haere i te roanga o te wā.
• He mirumiru nui, porotaka, he mākūkū .
• Ka mamae pea ēnei puku, ka kirikiri hoki.

ALCL pūnaha (te momo e pā ana ki ngā whekau o roto)

I tēnei āhuatanga, ka kitea ngā tohu e pā ana ki te PTCL.

Te lymphoma kaikōhuru taiao extranodal/pūtau-T, momo ihu

• Te ihu pupuhi, te āhua e mea ana kua purua te ihu.
• Te toto o te ihu .
• Ka pūkohu te roto o te ihu.
• Te pupuhi mamae o te mata .
• Ngā raruraru kanohi pērā i te rere o te wai mai i ngā kanohi me te mamae o te kanohi.

Te mate pukupuku pūtau-T pakeke/te mate toto toto (ATLL)

He mea noa ngā tohu PTCL mō ngā momo ATLL e whā.

He aha ngā take o te PTCL?

I te whakarapopototanga, ka puta te lymphoma pūtau-T Peripheral ina huri ngā pūtau-T i roto i tō tātou tinana ((huri)) hei pūtau matepukupuku. E mōhio ana koe, ko ēnei pūtau-T he momo toto ma e tiaki ana i a tātou mai i ngā whakaeke pēnei i ngā iroriki e uru mai ana ki roto i tō tātou tinana. Nō reira, ina huri ēnei pūtau-T, ka huri hei pūtau matepukupuku, ka tīmata te whakanui me te kore e taea te whakahaere . Ina whakanui pēnei rātou, ka kohia ki roto i ō tātou pukahukahu, te whēkau, te ate, me ētahi atu okana, ka hanga he pukupuku matepukupuku .

Kāore anō kia kitea e ngā tohunga he aha i pēnei ai te whakarerekētanga o ēnei pūtau-T.Heoi, kua kitea e ngā rangahau he hononga tōna ki ētahi āhuatanga hauora.

Hei tauira:

• Kua whakaatuhia e tētahi rangahau ā-ao whānui, ko te hunga whai mate celiac ka nui ake te mōrearea ki te whakawhanake i ētahi momo PTCL, tae atu ki te ALCL.
• Waihoki, ko te hunga kua pangia e te huaketo Epstein-Barr, tera pea ka nui ake te mōrearea ki te whakawhanake i te lymphoma extranodal natural killer/T-cell.
• Ko te hunga e pangia ana e te huaketo (Human T-cell lymphotropic virus Type 1 (HTLV-1)) he nui ake te mōrearea ki te whakawhanake i te (acute T-cell lymphoma/leukemia).

Me pēhea te tautuhi i te PTCL?

Tērā pea me mahi e ngā tākuta ētahi whakamātautau rerekē hei kimi i te momo PTCL e pāngia ana e ō raruraru hauora. Kei roto i ēnei ko ngā whakamātautau toto, ngā whakamātautau whakaahua, ngā whakamātautau koiora , me ngā whakamātautau ira hei ako i te hanganga ira o ngā pūtau matepukupuku.

Ngā whakamātautau toto

Ka whakahaerehia e ngā tākuta he whakamātautau toto hei tirotiro mō ngā huaketo e hono ana ki te PTCL. Kei roto i ēnei ko:

• Te tatau toto katoa (CBC)
• Te papatohu pākia whānui (CMP)
• Whakamātautau lactate dehydrogenase (LDH)
• Ngā whakamātautau mō te Hepatitis B me te Hepatitis C
• Whakamātautau huaketo ārai mate tangata (HIV)
• Ngā whakamātautau huaketo lymphotropic pūtau-T tangata Momo 1 (HTLV-Momo 1)

Ngā whakamātautau whakaahua

Mā ēnei matawai ka taea e ngā tākuta te tiki mōhiohio mō roto i tō tinana, inā koa ko ngā wāhi kei reira ngā puku matepukupuku.

• Matawai tomography rorohiko (CT)
• Matawai i te tomografi tukunga Positron (PET)
• Matawai whakaahua aukume (MRI)

Ngā koiora

Ko te tikanga tēnei ko te tango i tētahi wahi kiko iti mai i tētahi wāhi whakapae, ka tirotirohia i raro i tētahi karuārai. Koinei te huarahi matua hei whakaū i te mate .

• Te koiora o ngā kōpū lymph
• Te koiora kiri
• Te koiora wheua

He aha ngā wāhanga o te PTCL?

Ka whakamahia e ngā tākuta te whakatau i te taumata o te mate pukupuku hei whakarite maimoatanga, hei hoatu hoki i tētahi whakaaro mō ngā mea ka taea e koe te tumanako mai i te maimoatanga (matapae). Ka whakatauhia tēnei taumata e te momo PTCL me te wāhi kua horapa ngā pūtau-T mate pukupuku. Anei ngā taumata matua e whā o te PTCL:

• Wāhanga I: Kei roto noa i te pūtau kotahi, i te tautau pūtau kotahi rānei ngā pūtau-T matepukupuku.
• Wāhanga II: Kua pāngia e te mate pukupuku ngā pona lymph e rua, neke atu rānei, i te taha kotahi o tō tinana (hei tauira, i ia taha o tō kaki, i te taha kotahi rānei i runga ake, i raro rānei i te diaphragm).
• Wāhanga III: Kua horapa te mate pukupuku ki ngā kiko i runga ake me raro i tō diaphragm.
• Wāhanga IV: Haunga ngā rauropi, kua pāngia hoki ētahi atu okana e te mate pukupuku, pērā i ngā pukahukahu, te ate, te hinu wheua, te pūnaha nakunaku rānei.

He aha ngā maimoatanga mō te PTCL?

Nā te mea he maha ngā momo PTCL me te wāhanga o te mate pukupuku, kāore he maimoatanga kotahi e pai ana mō te katoa . Tērā pea ka rerekē ngā kōwhiringa maimoatanga i ia tangata, i ia tangata. Mā tō tākuta e whakatau te maimoatanga pai rawa atu māu. Anei ētahi o ngā maimoatanga tino noa:

• Te rongoā matū: He huinga o ngā momo rongoā matū rerekē. Koinei te maimoatanga matua e whakamahia whānuitia ana.
• Whakaora irahiko: Ka whakamahia tahitia tēnei me te rongoā matū, inā koa ka kitea te mate pukupuku i te rohe.
• Whakaora arotahi: He maimoatanga tēnei e arotahi ana ki ngā huringa ira motuhake (ngā whakarerekētanga ira) e meinga ai ngā pūtau hauora kia huri hei pūtau matepukupuku. He rerekē tēnei i te rongoā chemotherapy tuku iho.
• Te rongoā matū me te whakawhitinga pūtau take allogeneic: Ka taea te whakamahi i tēnei maimoatanga mō te PTCL kāore e aro ki te rongoā matū me te rongoā irahiko, ka hoki anō rānei i muri i te maimoatanga. He maimoatanga uaua ake tēnei.

I ētahi wā, ka taea e koe te whai wāhi atu ki ngā whakamātautau haumanu o ngā maimoatanga hou mō te PTCL. Kōrero ki tō tākuta mō tēnei.

He aha ngā pānga taha e pā ana ki te maimoatanga?

He maha ngā maimoatanga mate pukupuku ka pā mai ētahi pānga taha. Heoi, kāore e pāngia te katoa e ēnei pānga taha katoa, ā, ka rerekē te kaha. Hei tauira, ko ngā pānga taha o te chemotherapy me te radiation therapy ka uru atu ki:

• Ngenge
• Kohu roro i puta mai i te rongoā matū - he kare ā-roto o te kohu roro, te ngaronga o te mahara, me te uaua ki te arotahi.
• Whakapairuaki me te ruaki
• Te ngaro o te makawe
• Ngā mate waha
• He ngāwari ake te pāngia e ngā mate urutā

He maha ngā huarahi inaianei hei whakahaere i ēnei pānga taha, nō reira me kōrero anō hoki ki tō tākuta.

He aha te matapae mō te PTCL?

Ko tēnei e whakawhirinaki ana ki te momo PTCL, te wāhanga o te mate pukupuku, tō hauora whānui, me te mea kei te ora te mate pukupuku (remission) me te maimoatanga.Ko te tikanga o te "whakakorenga mate" kāore he tohu, ā, kāore hoki he tohu o te mate pukupuku e kitea ana i roto i ngā whakamātautau. I ētahi wā, ka taea te whakaora katoa i te PTCL mā te whakamahi i ngā maimoatanga paerewa.

Heoi anō, he maha ngā momo lymphoma pūtau-T ā-taha ka hoki mai anō ((recur)) . Mēnā ka puta tēnei, me hiahia pea koe ki tētahi atu maimoatanga, ki tētahi atu momo maimoatanga rānei.

He mea maori noa iho te hiahia ki te mōhio he aha ngā mea ka tumanakohia mai i tō maimoatanga. Ko tō tākuta te tangata pai rawa atu hei mōhio mō tō āhua. Nō reira, kia tuwhera, kia pono hoki ki a ia mō tēnei mea, kaua hoki e wehi ki te pātai.

Ka taea te ārai i te PTCL?

Engari, kāo, e ai ki tā mātou e mōhio ana, kāore he huarahi motuhake hei ārai i tēnei . Ko tēnei lymphoma ka puta mai i te whanonga kino o ngā pūtau-T, ā, ka huri hei matepukupuku. Kāore he mea e taea e tātou te mahi hei ārai i tēnei. Heoi, mā te karo i ētahi āhuatanga mōrearea (hei tauira, te huaketo HTLV-1) ka whakaiti i te mōrearea o te whakawhanake i ngā momo PTCL e pā ana.

Me pēhea taku tiaki i ahau anō? (Te noho tahi me te PTCL)

He momo mate pukupuku onge, tere te tipu o te lymphoma pūtau-T ā-peripheral. Mena kei a koe te PTCL, anei ētahi tohutohu hei āwhina i a koe ki te ora me te mate:

• Whakaarohia te tiaki mamae: Ka taea e tēnei tiaki te āwhina i a koe ki te whakahaere i ngā tohu me ngā pānga taha o te maimoatanga. Heoi anō, ka taea e tō rōpū tiaki mamae te tautoko i a koe ki te whakatau i ngā wero kare ā-roto (te pouri, te wehi, te manukanuka) e pā mai ana me te noho me tētahi mate kino.
• Kimihia he tautoko: Nā te mea he mate pukupuku onge te PTCL, tera pea ka whakaaro koe ko koe anake te tangata e pāngia ana e tēnei mate. Engari kāore koe e hiahia ki te mahi ko koe anake. Kōrero ki tō rōpū hauora, ka kimihia ngā rōpū tautoko hei hono atu ki ētahi atu e pāngia ana e te mate kotahi. He mea nui te whakapuaki i ngā wheako me te whiwhi tautoko mai i ētahi atu i tēnei wā.
• Whakawāteahia he wā mōu ake (Manaaki i a koe anō): He mate taumaha te mate pukupuku. He mea nui te tiaki i a koe anō ina noho tahi koe me te PTCL. Kōrero ki tō rōpū hauora mō ngā huarahi hei whakahaere i te ahotea (whakaaroaro, mahi manawa, whai wāhi ki tētahi mahi whakangahau), me pēhea te hanga i tētahi kai totika hei pupuri i a koe kia kaha i te wā e rongoatia ana. Kia nui te moe.

He aha ngā pātai me pātai atu e au ki taku tākuta?

Kaua e wareware ki te pātai i ēnei pātai ina kite koe i tō tākuta:

• He aha te momo lymphoma pūtau-T Peripheral kei a au? He aha tōna ingoa?
• He aha te taumata o tōku mate? Kua horapa pēhea?
• He aha ngā kōwhiringa maimoatanga kei a au? He aha ngā painga me ngā huakore o ia maimoatanga?
• He aha te momo angitu e taea te tumanako mai i ēnei maimoatanga?
• He aha ngā pānga taha o te maimoatanga? Me pēhea te whakahaere i aua pānga?
• Me whakaaro ahau ki tētahi maimoatanga hou e ahu mai ana i te rangahau ((whakamātautau haumanu))? He tika ēnei mōku?
• He aha ngā huringa me mahi e au i roto i tōku āhua noho?

Karere Whakamutunga mō te Tango ki te Kāinga

Ko te lymphoma pūtau-T ā-rohe (PTCL) he momo matepukupuku toto onge engari he mea nui. Ka puta mai i te wā e whakarerekē ana ngā pūtau-T e tiaki ana i ō tātou tinana, ā, ka noho hei matepukupuku. Ahakoa he rite tonu te pūtake o aua pūtau, he rerekē te hanganga ira o ia pūtau. Nā te mea ka pāngia ngā wāhanga rerekē o te tinana e te PTCL, he uaua pea te tautuhi me te rongoā i ētahi wā.

Engari, kia mau tonu te tumanako! Kei te rapu tonu ngā kairangahau hauora i ngā maimoatanga hou, whai hua ake e aro ana ki ngā huringa ira o te PTCL. Mena kua tohua koe he PTCL, kaua e mataku, me kōrero noa ki tō rōpū hauora . Pātai atu mēnā he maimoatanga rangahau hou (whakamātautau haumanu) e tika ana mō tō āhua motuhake. Mā te mōhiotanga tika me te tautoko a ō whanaunga, ka whai mana koe ki te aro atu ki tēnei wero!