ꯏꯒꯤ ꯈꯣꯡꯖꯦꯜ ꯑꯃꯅꯥ ꯀꯦꯟꯁꯔ ꯈꯉꯗꯣꯛꯅꯕꯒꯤ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯅꯧꯕꯥ ꯄꯥꯝꯕꯩ (ꯂꯤꯛꯌꯨꯏꯗ ꯕꯥꯏꯑꯣꯞꯁꯤ)ꯒꯤ ꯃꯇꯥꯡꯗꯥ ꯈꯉꯂꯁꯤ?

ꯃꯤꯑꯣꯏ ꯀꯌꯥ ꯑꯃꯅꯥ "ꯕꯥꯏꯑꯣꯞꯁꯤ" ꯍꯥꯌꯕꯥ ꯋꯥꯍꯩ ꯑꯁꯤ ꯇꯥꯕꯗꯥ ꯌꯥꯝꯅꯥ ꯋꯥꯅꯥ ꯊꯣꯀꯏ, ꯅꯠꯇꯦ? ꯃꯈꯣꯌꯅꯥ "ꯕꯥꯏꯑꯣꯞꯁꯤ" ꯍꯥꯌꯕꯥ ꯋꯥꯍꯩ ꯑꯁꯤ ꯇꯥꯕꯗꯥ ꯈꯔꯥ ꯂꯥꯡꯇꯛꯅꯕꯥ ꯐꯥꯎꯕꯥ ꯍꯥꯌꯕꯁꯤ ꯅꯣꯔꯃꯦꯂꯅꯤ꯫ ꯑꯗꯨꯕꯨ ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯍꯥꯛꯀꯤ ꯏꯒꯤ ꯊꯣꯡ ꯑꯃꯥ ꯈꯛꯇꯃꯛ ꯂꯧꯗꯨꯅꯥ ꯀꯦꯟꯁꯔ ꯁꯦꯂꯁꯤꯡꯒꯤ ꯃꯔꯃꯗꯥ ꯈꯉꯅꯕꯒꯤ ꯄꯥꯝꯕꯩ ꯑꯃꯥ ꯂꯩꯔꯝꯂꯕꯗꯤ ꯈꯟꯗꯨꯅꯥ ꯌꯦꯡꯕꯤꯌꯨ? ꯃꯁꯤ ꯑꯩꯈꯣꯌꯅꯥ ꯑꯉꯀꯄꯥ, ꯑꯅꯧꯕꯥ ꯃꯇꯃꯒꯤ ꯇꯦꯛꯅꯣꯂꯣꯖꯤ ꯑꯁꯤꯕꯨ "ꯂꯤꯛꯌꯨꯏꯗ ꯕꯥꯏꯑꯣꯞꯁꯤ" ꯍꯥꯌꯅꯥ ꯀꯧꯏ꯫ ꯃꯁꯤꯅꯥ ꯀꯦꯟꯁꯔꯒꯥ ꯂꯥꯟꯊꯦꯡꯅꯔꯤꯕꯥ ꯃꯤꯑꯣꯏꯁꯤꯡꯗꯥ ꯑꯆꯧꯕꯥ ꯑꯥꯁꯥ ꯑꯃꯥ ꯄꯨꯔꯛꯂꯦ꯫

ꯌꯥꯝꯅꯥ ꯂꯥꯏꯅꯥ ꯍꯥꯌꯔꯕꯗꯥ, ꯃꯁꯤ ꯂꯤꯛꯕꯤꯗ ꯕꯥꯏꯑꯣꯞꯁꯤ ꯍꯥꯌꯕꯁꯤ ꯀꯔꯤꯅꯣ?

ꯂꯤꯛꯕꯤꯗ ꯕꯥꯏꯑꯣꯞꯁꯤ ꯑꯁꯤ ꯇꯤꯎꯃꯔꯁꯤꯡ ꯈꯉꯗꯣꯛꯅꯕꯥ ꯁꯤꯖꯤꯟꯅꯕꯥ ꯑꯈꯟꯅꯕꯥ ꯕ꯭ꯂꯗ ꯇꯦꯁ꯭ꯠ ꯑꯃꯅꯤ꯫ ꯑꯩꯈꯣꯌꯒꯤ ꯍꯀꯆꯥꯡꯗꯥ ꯇꯤꯎꯃꯔ ꯑꯃꯥ ꯁꯦꯃꯒꯠꯂꯀꯄꯥ ꯑꯃꯁꯨꯡ ꯍꯦꯅꯒꯠꯂꯀꯄꯥ ꯃꯇꯃꯗꯥ ꯇꯤꯎꯃꯔ ꯑꯗꯨꯒꯤ ꯑꯄꯤꯀꯄꯥ ꯁꯔꯨꯀꯁꯤꯡ ꯑꯗꯨ ꯆꯦꯟꯊꯔꯀꯏ ꯑꯃꯁꯨꯡ ꯏꯗꯥ ꯆꯪꯂꯀꯏ ꯍꯥꯌꯅꯥ ꯈꯅꯕꯤꯌꯨ꯫ ꯑꯔꯤꯕꯥ ꯋꯥꯜ ꯑꯃꯗꯒꯤ ꯄ꯭ꯂꯥꯁ꯭ꯇꯔꯒꯤ ꯁꯔꯨꯀꯁꯤꯡ ꯊꯨꯒꯥꯏꯔꯀꯄꯒꯨꯝꯅꯥ꯫ ꯂꯤꯛꯕꯤꯗ ꯕꯥꯏꯑꯣꯞꯁꯤ ꯇꯦꯁ꯭ꯠ ꯑꯁꯤꯅꯥ ꯏꯗꯥ ꯆꯪꯂꯀꯄꯥ ꯀꯦꯟꯁꯔꯒꯤ ꯁꯔꯨꯀꯁꯤꯡ ꯑꯗꯨ ꯑꯩꯈꯣꯌꯅꯥ ꯈꯉꯗꯣꯀꯄꯥ ꯉꯃꯒꯅꯤ꯫

ꯏꯗꯥ ꯌꯥꯑꯣꯕꯥ ꯌꯥꯕꯥ ꯃꯔꯨ ꯑꯣꯏꯕꯥ ꯋꯥꯐꯝ ꯑꯅꯤ ꯂꯩ:

• ꯁꯔꯛꯌꯨꯂꯦꯇꯤꯡ ꯇꯤꯎꯃꯔ ꯁꯦꯂꯁꯤꯡ (CTCs): ꯃꯈꯣꯌ ꯑꯁꯤ ꯇꯤꯎꯃꯔꯗꯒꯤ ꯂꯥꯄꯊꯣꯛꯅꯥ ꯂꯩꯕꯥ ꯑꯃꯁꯨꯡ ꯏꯒꯤ ꯈꯣꯡꯖꯦꯂꯒꯤ ꯈꯨꯠꯊꯥꯡꯗꯥ ꯍꯀꯆꯥꯡ ꯄꯨꯝꯕꯥ ꯆꯠꯂꯤꯕꯥ ꯑꯄꯨꯅꯕꯥ ꯀꯦꯟꯁꯔ ꯁꯦꯂꯁꯤꯡꯅꯤ꯫
• ꯁꯔꯀꯨꯂꯦꯇꯤꯡ ꯇꯤꯎꯃꯔ DNA (ctDNA): ꯃꯁꯤ ꯀꯦꯟꯁꯔ ꯁꯦꯂꯁꯤꯡꯒꯤ ꯃꯅꯨꯡꯗꯥ ꯂꯩꯕꯥ ꯖꯦꯅꯦꯇꯤꯛ ꯏꯅꯐꯣꯔꯃꯦꯁꯟ (DNA)ꯒꯤ ꯑꯄꯤꯀꯄꯥ ꯁꯔꯨꯀꯁꯤꯡꯅꯤ꯫ DNA ꯑꯁꯤ ꯁꯦꯜ ꯑꯃꯅꯥ ꯊꯕꯛ ꯇꯧꯕꯗꯥ ꯃꯊꯧ ꯇꯥꯕꯥ ꯏꯅꯁ꯭ꯠꯔꯛꯁꯟ ꯄꯨꯝꯅꯃꯛ ꯌꯥꯎꯕꯥ "ꯕ꯭ꯂꯨꯞꯔꯤꯟꯇ" ꯑꯃꯒꯨꯝꯅꯥ ꯑꯣꯏ꯫ ꯀꯦꯟꯁꯔ ꯁꯦꯂꯁꯤꯡꯅꯥ ꯁꯤꯕꯥ ꯃꯇꯃꯗꯥ ꯗꯤ.ꯑꯦꯟ.ꯑꯦ.ꯒꯤ ꯁꯔꯨꯀꯁꯤꯡ ꯑꯁꯤ ꯏꯗꯥ ꯊꯨꯃꯖꯤꯜꯂꯤ꯫

ꯅꯍꯥꯛꯀꯤ ꯏꯗꯥ ꯁꯤ.ꯇꯤ.ꯁꯤ.ꯁꯤꯡ ꯅꯠꯠꯔꯒꯥ ꯁꯤ.ꯇꯤ.ꯗꯤ.ꯑꯦꯟ.ꯑꯦ.ꯁꯤꯡ ꯑꯁꯤ ꯂꯩꯕꯅꯥ ꯅꯍꯥꯛꯀꯤ ꯍꯀꯆꯥꯡꯒꯤ ꯃꯐꯝ ꯑꯃꯗꯥ ꯀꯦꯟꯁꯔ ꯂꯩ ꯍꯥꯌꯕꯒꯤ ꯑꯐꯕꯥ ꯈꯨꯗꯝ ꯑꯃꯅꯤ꯫ ꯃꯁꯤꯗꯁꯨ ꯅꯠꯇꯅꯥ, ꯏꯅꯐꯣꯔꯃꯦꯁꯅꯁꯤꯡ ꯑꯁꯤꯅꯥ ꯑꯩꯈꯣꯌꯗꯥ ꯀꯦꯟꯁꯔꯒꯤ ꯖꯦꯅꯦꯇꯤꯛ ꯏꯅꯐꯣꯔꯃꯦꯁꯅꯒꯤ ꯃꯇꯥꯡꯗꯥ ꯑꯆꯧꯕꯥ ꯋꯥꯈꯜꯂꯣꯟ ꯑꯃꯥ ꯄꯤꯕꯥ ꯉꯃꯒꯅꯤ꯫ ꯏꯅꯐꯣꯔꯃꯦꯁꯟ ꯑꯗꯨ ꯁꯤꯖꯤꯟꯅꯗꯨꯅꯥ, ꯅꯍꯥꯛꯀꯤ ꯗꯣꯛꯇꯔꯅꯥ ꯅꯍꯥꯛꯀꯤꯗꯃꯛꯇꯥ ꯀꯔꯤ ꯂꯥꯏꯌꯦꯡ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯐꯕꯒꯦ ꯍꯥꯌꯕꯗꯨ ꯂꯦꯄꯊꯣꯀꯄꯗꯥ ꯃꯇꯦꯡ ꯄꯥꯡꯒꯅꯤ꯫

ꯃꯁꯤ ꯍꯧꯖꯤꯀꯁꯨ ꯌꯥꯝꯅꯥ ꯑꯅꯧꯕꯥ ꯇꯦꯛꯅꯣꯂꯣꯖꯤ ꯑꯃꯅꯤ, ꯑꯗꯨꯕꯨ ꯃꯁꯤꯅꯥ ꯀꯦꯟꯁꯔ ꯂꯥꯌꯦꯡꯕꯗꯥ ꯑꯍꯣꯡꯕꯥ ꯑꯃꯥ ꯄꯨꯔꯀꯄꯥ ꯉꯃꯒꯅꯤ ꯍꯥꯌꯅꯥ ꯁꯥꯏꯟꯇꯤꯁ꯭ꯇꯁꯤꯡꯅꯥ ꯊꯥꯖꯩ꯫ ꯌꯨ.ꯑꯦꯁ.ꯀꯤ ꯐꯨꯗ ꯑꯃꯁꯨꯡ ꯗ꯭ꯔꯒ ꯑꯦꯗꯃꯤꯅꯤꯁ꯭ꯠꯔꯦꯁꯟ (ꯑꯦꯐ.ꯗꯤ.ꯑꯦ.)ꯒꯨꯝꯕꯥ ꯑꯦꯖꯦꯟꯁꯤꯁꯤꯡꯅꯥ ꯑꯌꯥꯕꯥ ꯄꯤꯔꯕꯥ ꯇ꯭ꯔꯥꯏꯑꯦꯜ ꯀꯌꯥ ꯑꯃꯥ ꯍꯥꯟꯅꯗꯒꯤ ꯂꯩꯔꯦ꯫

ꯃꯁꯤ ꯆꯥꯡ ꯅꯥꯏꯅꯥ ꯕꯥꯏꯑꯣꯞꯁꯤ ꯇꯧꯕꯒꯥ ꯀꯔꯝꯅꯥ ꯈꯦꯠꯅꯕꯒꯦ?

ꯑꯅꯤꯁꯤꯒꯤ ꯃꯔꯛꯇꯥ ꯑꯆꯧꯕꯥ ꯈꯦꯠꯅꯕꯥ ꯑꯃꯥ ꯂꯩꯔꯤ꯫ ꯆꯥꯡ ꯅꯥꯏꯅꯥ ꯕꯥꯏꯑꯣꯞꯁꯤ ꯑꯃꯗꯥ, ꯀꯦꯟꯁꯔꯅꯥ ꯅꯥꯕꯥ ꯇꯤꯎꯃꯔꯗꯒꯤ ꯍꯀꯊꯦꯡꯅꯅꯥ ꯇꯤꯁ꯭ꯌꯨ ꯁꯦꯝꯄꯜ ꯑꯃꯥ ꯂꯧꯗꯨꯅꯥ ꯇꯦꯁ꯭ꯠ ꯇꯧꯏ꯫ ꯑꯗꯨꯝ ꯑꯣꯏꯅꯃꯛ, ꯂꯤꯛꯌꯨꯏꯗ ꯕꯥꯏꯑꯣꯞꯁꯤ ꯑꯃꯗꯥ, ꯇꯤꯎꯃꯔ ꯑꯗꯨꯗꯒꯤ ꯁꯦꯝꯄꯜ ꯑꯃꯥ ꯂꯧꯗꯦ꯫ ꯃꯗꯨꯒꯤ ꯃꯍꯨꯠꯇꯥ, ꯃꯁꯤꯅꯥ ꯏꯗꯥ ꯀꯦꯟꯁꯔ (ꯀꯦꯟꯁꯔ ꯁꯦꯂꯁꯤꯡ ꯅꯠꯠꯔꯒꯥ ꯗꯤ.ꯑꯦꯟ.ꯑꯦ.ꯒꯤ ꯁꯔꯨꯀꯁꯤꯡ)ꯒꯤ ꯄ꯭ꯔꯃꯥꯅꯁꯤꯡ ꯊꯤꯔꯤ꯫

ꯑꯅꯤꯁꯤꯒꯤ ꯃꯔꯛꯇꯥ ꯂꯩꯔꯤꯕꯥ ꯈꯦꯟꯅꯕꯥ ꯑꯗꯨ ꯍꯦꯟꯅꯥ ꯃꯌꯦꯛ ꯁꯦꯡꯍꯟꯅꯕꯥ ꯇꯦꯕꯜ ꯑꯁꯤ ꯌꯦꯡꯁꯤ꯫

ꯂꯤꯛꯕꯤꯗ ꯕꯥꯏꯑꯣꯞꯁꯤ ꯑꯃꯗꯥ, ꯍꯀꯆꯥꯡꯗꯥ ꯀꯦꯟꯁꯔ ꯂꯩꯔꯕꯁꯨ ꯃꯇꯝ ꯑꯗꯨꯗꯥ ꯂꯧꯈꯤꯕꯥ ꯏꯒꯤ ꯁꯦꯝꯄꯜ ꯑꯗꯨꯗꯥ ꯀꯦꯟꯁꯔ ꯁꯦꯂꯁꯤꯡ ꯌꯥꯑꯣꯗꯕꯒꯤ ꯑꯄꯤꯀꯄꯥ ꯆꯥꯡ ꯂꯩ꯫ ꯑꯗꯨꯝ ꯑꯣꯏꯅꯃꯛ, ꯀꯔꯤꯒꯨꯝꯕꯥ ꯀꯦꯟꯁꯔ ꯂꯥꯀꯄꯥ ꯇꯥꯔꯕꯗꯤ, ꯃꯁꯤꯅꯥ ꯄꯤꯔꯤꯕꯥ ꯏꯅꯐꯣꯔꯃꯦꯁꯟ ꯑꯁꯤ ꯂꯥꯏꯌꯦꯡꯕꯒꯤ ꯊꯧꯔꯥꯡ ꯇꯧꯕꯗꯥ ꯃꯃꯜ ꯌꯥꯝꯃꯤ꯫

ꯀꯔꯤ ꯀꯦꯁꯁꯤꯡꯗꯥ ꯂꯤꯛꯌꯨꯏꯗ ꯕꯥꯏꯑꯣꯞꯁꯤ ꯄꯥꯡꯊꯣꯀꯄꯒꯦ?

ꯃꯍꯧꯁꯥꯅꯥ ꯗꯣꯛꯇꯔ ꯑꯃꯅꯥ ꯀꯦꯟꯁꯔ ꯑꯁꯤ ꯍꯦꯟꯅꯥ ꯆꯥꯎꯈꯠꯂꯛꯂꯤꯕꯥ ꯑꯃꯁꯨꯡ ꯍꯀꯆꯥꯡꯒꯤ ꯑꯇꯩ ꯃꯐꯃꯁꯤꯡꯗꯥ ꯁꯟꯗꯣꯀꯈ꯭ꯔꯕꯥ ꯑꯅꯥꯕꯁꯤꯡꯗꯥ (ꯃꯦꯇꯥꯁ꯭ꯇꯦꯇꯤꯛ ꯀꯦꯟꯁꯔ) ꯇꯦꯁ꯭ꯠ ꯑꯁꯤ ꯔꯤꯀꯃꯦꯟꯗ ꯇꯧꯏ꯫ ꯃꯁꯤꯅꯥ ꯃꯈꯣꯌꯗꯥ ꯃꯊꯪꯗꯥ ꯀꯔꯤ ꯇꯧꯒꯗꯒꯦ ꯍꯥꯌꯕꯗꯨ ꯂꯦꯄꯊꯣꯀꯄꯗꯥ ꯃꯇꯦꯡ ꯄꯥꯡꯏ, ꯃꯔꯨꯑꯣꯏꯅꯥ ꯀꯔꯤꯒꯨꯝꯕꯥ ꯍꯧꯖꯤꯛ ꯂꯩꯔꯤꯕꯥ ꯂꯥꯏꯌꯦꯡꯁꯤꯡ ꯑꯁꯤ ꯐꯖꯅꯥ ꯊꯕꯛ ꯇꯧꯗ꯭ꯔꯕꯗꯤ꯫

ꯇꯦꯁ꯭ꯠ ꯑꯁꯤ ꯇꯧꯕꯒꯤ ꯃꯔꯨꯑꯣꯏꯕꯥ ꯃꯔꯝ ꯀꯌꯥ ꯂꯩꯔꯤ:

꯱.ꯄ꯭ꯔꯣꯒ꯭ꯅꯣꯁꯤꯁ ꯂꯦꯄꯊꯣꯀꯄꯥ꯫

ꯏꯗꯥ ꯂꯩꯕꯥ ꯁꯤ.ꯇꯤ.ꯁꯤ.ꯁꯤꯡ (ꯀꯦꯟꯁꯔ ꯁꯦꯂꯁꯤꯡ)ꯒꯤ ꯃꯁꯤꯡ ꯑꯁꯤꯅꯥ ꯑꯅꯥꯕꯥ ꯑꯗꯨꯒꯤ ꯐꯤꯚꯃꯒꯤ ꯃꯇꯥꯡꯗꯥ ꯑꯀꯛꯅꯕꯥ ꯋꯥꯈꯜꯂꯣꯟ ꯑꯃꯥ ꯄꯤꯕꯥ ꯉꯃꯒꯅꯤ꯫ ꯏꯗꯥ ꯁꯤ.ꯇꯤ.ꯁꯤ.ꯒꯤ ꯃꯁꯤꯡ ꯅꯦꯝꯕꯥ ꯍꯥꯌꯕꯁꯤꯅꯥ ꯌꯥꯝꯅꯥ ꯐꯕꯥ ꯀꯟꯗꯤꯁꯟ ꯑꯃꯥ ꯍꯥꯌꯕꯅꯤ꯫ ꯑꯗꯨꯝ ꯑꯣꯏꯅꯃꯛ, ꯀꯔꯤꯒꯨꯝꯕꯥ ꯁꯤ.ꯇꯤ.ꯁꯤ.ꯁꯤꯡ ꯌꯥꯝꯅꯥ ꯂꯩꯔꯕꯗꯤ ꯂꯥꯌꯅꯥ ꯑꯁꯤ ꯈꯔꯥ ꯍꯦꯟꯅꯥ ꯁꯥꯊꯤꯕꯥ ꯑꯣꯏ ꯍꯥꯌꯕꯅꯤ꯫ ꯃꯁꯤꯒꯤ ꯃꯑꯣꯡ ꯑꯁꯤꯅꯥ ꯗꯣꯛꯇꯔꯁꯤꯡꯅꯥ ꯃꯇꯝ ꯃꯇꯃꯒꯤ ꯑꯣꯏꯅꯥ ꯇꯦꯁ꯭ꯠ ꯑꯁꯤ ꯇꯧꯕꯥ ꯌꯥꯏ, ꯂꯥꯌꯅꯥ ꯑꯁꯤꯅꯥ ꯂꯥꯌꯦꯡꯕꯗꯥ ꯀꯔꯝꯅꯥ ꯔꯦꯁ꯭ꯄꯣꯟꯁ ꯇꯧꯔꯤꯕꯒꯦ ꯍꯥꯌꯕꯗꯨ ꯌꯦꯡꯕꯥ ꯌꯥꯏ ꯑꯃꯁꯨꯡ ꯃꯁꯤꯒꯤ ꯃꯇꯨꯡ ꯏꯟꯅꯥ ꯂꯥꯌꯦꯡ ꯍꯣꯡꯗꯣꯀꯄꯥ ꯌꯥꯏ꯫

ꯂꯥꯌꯦꯡꯕꯒꯤ ꯋꯥꯔꯦꯞ ꯂꯧꯕꯥ ꯲

ꯃꯁꯤ ꯂꯤꯛꯕꯤꯗ ꯕꯥꯏꯑꯣꯞꯁꯤꯒꯤ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯃꯃꯜ ꯌꯥꯝꯂꯕꯥ ꯀꯥꯟꯅꯕꯁꯤꯡꯒꯤ ꯃꯅꯨꯡꯗꯥ ꯑꯃꯅꯤ꯫ ꯀꯦꯟꯁꯔ ꯁꯦꯜ ꯈꯔꯗꯗꯤ ꯑꯀꯛꯅꯕꯥ ꯖꯦꯅꯦꯇꯤꯛ ꯑꯣꯏꯕꯥ ꯑꯁꯣꯌꯕꯁꯤꯡ ꯂꯩ꯫ ꯑꯍꯣꯡꯕꯁꯤꯡ ꯑꯗꯨ ꯈꯛꯇꯗꯥ ꯄꯥꯟꯗꯝ ꯊꯝꯂꯤꯕꯥ ꯑꯀꯛꯅꯕꯥ ꯗ꯭ꯔꯒꯁꯤꯡ ꯂꯩꯔꯤ꯫ ꯑꯩꯈꯣꯌꯅꯥ ꯃꯁꯤꯕꯨ ``ꯇꯥꯔꯒꯦꯠ ꯇꯧꯔꯕꯥ ꯊꯦꯔꯥꯄꯤ'' ꯍꯥꯌꯅꯥ ꯀꯧꯏ꯫ ꯌꯥꯝꯅꯥ ꯂꯥꯏꯅꯥ ꯍꯥꯌꯔꯕꯗꯥ, ꯃꯁꯤ ꯑꯀꯛꯅꯕꯥ ꯀꯤ ꯑꯃꯈꯛꯇꯅꯥ ꯍꯥꯡꯗꯣꯀꯄꯥ ꯌꯥꯕꯥ ꯂꯣꯛ ꯑꯃꯒꯨꯝꯕꯅꯤ꯫ ꯂꯤꯛꯌꯨꯏꯗ ꯕꯥꯏꯑꯣꯞꯁꯤꯅꯥ ꯅꯍꯥꯛꯀꯤ ꯀꯦꯟꯁꯔ ꯁꯦꯂꯁꯤꯡꯗꯥ ꯀꯔꯤ ꯃꯈꯂꯒꯤ "ꯂꯣꯛ" ꯂꯩꯕꯒꯦ ꯍꯥꯌꯕꯗꯨ ꯈꯪꯍꯅꯕꯥ ꯉꯃꯒꯅꯤ꯫ ꯃꯗꯨꯒꯤ ꯃꯇꯨꯡꯗꯥ ꯅꯍꯥꯛꯀꯤ ꯗꯣꯛꯇꯔꯅꯥ ꯅꯍꯥꯀꯄꯨ ꯃꯗꯨꯒꯤꯗꯃꯛꯇꯥ ꯑꯆꯨꯝꯕꯥ "ꯀꯤ" (ꯗ꯭ꯔꯒ) ꯄꯤꯕꯥ ꯌꯥꯏ꯫

3. ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯣꯔꯃꯦꯜ ꯕꯥꯏꯑꯣꯞꯁꯤ ꯑꯃꯥ ꯄꯥꯡꯊꯣꯀꯄꯥ ꯉꯃꯗ꯭ꯔꯕꯗꯤ꯫

ꯀꯔꯤꯒꯨꯝꯕꯥ ꯃꯇꯃꯗꯥ ꯄꯦꯁꯦꯟꯇ ꯑꯃꯅꯥ ꯆꯥꯡ ꯅꯥꯏꯅꯥ ꯕꯥꯏꯑꯣꯞꯁꯤ ꯇꯧꯕꯥ ꯉꯃꯗꯅꯥ ꯌꯥꯝꯅꯥ ꯋꯥꯅꯥ ꯊꯣꯀꯄꯥ ꯌꯥꯏ꯫ ꯅꯠꯠꯔꯒꯥ ꯇꯤꯎꯃꯔ ꯑꯗꯨ ꯕ꯭ꯔꯦꯟ ꯅꯠꯠꯔꯒꯥ ꯂꯪꯁꯒꯨꯝꯕꯥ ꯑꯣꯔꯒꯥꯟ ꯑꯃꯒꯤ ꯌꯥꯝꯅꯥ ꯁꯦꯟꯁꯤꯇꯤꯚ ꯑꯣꯏꯕꯥ ꯑꯃꯁꯨꯡ ꯌꯧꯕꯥ ꯉꯃꯗꯕꯥ ꯁꯔꯨꯛ ꯑꯃꯗꯥ ꯂꯩꯕꯥ ꯌꯥꯏ꯫ ꯀꯔꯤꯒꯨꯝꯕꯥ ꯑꯁꯤꯒꯨꯝꯕꯥ ꯃꯐꯝ ꯑꯃꯗꯒꯤ ꯄꯣꯠꯁꯛ ꯑꯃꯥ ꯀꯀꯊꯠꯂꯕꯗꯤ, ꯑꯀꯣꯌꯕꯗꯥ ꯂꯩꯔꯤꯕꯥ ꯍꯀꯁꯦꯜ ꯐꯕꯥ ꯇꯤꯁꯨꯁꯤꯡꯗꯥ ꯑꯃꯥꯡ-ꯑꯇꯥ ꯊꯣꯀꯍꯅꯕꯒꯤ ꯔꯤꯁ꯭ꯛ ꯂꯩ꯫ ꯑꯁꯤꯒꯨꯝꯕꯥ ꯀꯦꯁꯁꯤꯡꯗꯗꯤ, ꯔꯤꯁ꯭ꯛ ꯂꯩꯇꯕꯥ ꯂꯤꯛꯌꯨꯏꯗ ꯕꯥꯏꯑꯣꯞꯁꯤ ꯑꯁꯤ ꯌꯥꯝꯅꯥ ꯀꯥꯟꯅꯩ꯫

ꯍꯧꯖꯤꯛ ꯑꯌꯥꯕꯥ ꯄꯤꯔꯕꯥ ꯂꯤꯛꯕꯤꯗ ꯕꯥꯏꯑꯣꯞꯁꯤ ꯇꯦꯁ꯭ꯇꯁꯤꯡ ꯑꯁꯤ ꯀꯔꯤꯅꯣ?

ꯃꯥꯂꯦꯝ ꯁꯤꯅꯕꯥ ꯊꯨꯡꯅꯥ ꯔꯤꯁꯔꯆ ꯇꯧꯕꯒꯤ ꯊꯕꯛ ꯀꯌꯥ ꯆꯠꯊꯔꯤ꯫ ꯍꯧꯖꯤꯛ ꯌꯨꯅꯥꯏꯇꯦꯗ ꯁ꯭ꯇꯦꯇꯁꯇꯥ ꯑꯦꯐ.ꯗꯤ.ꯑꯦ.ꯅꯥ ꯑꯌꯥꯕꯥ ꯄꯤꯔꯕꯥ ꯑꯆꯧꯕꯥ ꯇ꯭ꯔꯥꯏꯑꯦꯜ ꯀꯌꯥ ꯑꯃꯥ ꯂꯩꯔꯤ, ꯃꯁꯤꯅꯥ ꯇꯥꯀꯄꯗꯤ ꯃꯈꯣꯌꯁꯤꯡ ꯑꯁꯤ ꯁꯦꯐꯇꯤ ꯑꯃꯁꯨꯡ ꯑꯦꯛꯌꯨꯔꯦꯁꯤꯒꯤꯗꯃꯛꯇꯥ ꯃꯄꯨꯡ ꯐꯥꯅꯥ ꯇꯦꯁ꯭ꯠ ꯇꯧꯈ꯭ꯔꯦ:

• ꯁꯦꯜ ꯁꯔꯆ® ꯁꯔꯛꯌꯨꯂꯦꯇꯤꯡ ꯇꯤꯎꯃꯔ ꯁꯦꯜ (CTC) ꯇꯦꯁ꯭ꯠ: ꯃꯁꯤꯅꯥ ꯏꯗꯥ ꯂꯩꯕꯥ CTCꯁꯤꯡ (ꯀꯦꯟꯁꯔ ꯁꯦꯂꯁꯤꯡ)ꯒꯤ ꯃꯁꯤꯡ ꯑꯗꯨ ꯂꯦꯄꯊꯣꯀꯏ꯫ ꯃꯁꯤ ꯍꯀꯆꯥꯡ ꯄꯨꯝꯕꯗꯥ ꯁꯟꯗꯣꯔꯀꯄꯥ ꯕ꯭ꯔꯦꯁ꯭ꯠ, ꯄ꯭ꯔꯣꯁ꯭ꯇꯦꯠ ꯑꯃꯁꯨꯡ ꯀꯣꯂꯣꯟ ꯀꯦꯟꯁꯔ ꯂꯩꯕꯥ ꯑꯅꯥꯕꯁꯤꯡꯒꯤ ꯐꯤꯚꯝ ꯌꯦꯡꯁꯤꯟꯅꯕꯥ ꯁꯤꯖꯤꯟꯅꯩ꯫
• cobas® EGFR ꯃ꯭ꯌꯨꯇꯦꯁꯟ ꯇꯦꯁ꯭ꯠ v2: ꯃꯁꯤꯅꯥ ctDNA (ꯀꯦꯟꯁꯔ DNA ꯐ꯭ꯔꯦꯀꯃꯦꯟꯇꯁꯤꯡ) ꯇꯦꯁ꯭ꯠ ꯇꯧꯏ꯫ ꯃꯁꯤꯅꯥ ꯂꯪꯁ ꯀꯦꯟꯁꯔ (ꯅꯟ-ꯁ꯭ꯃꯣꯜ ꯁꯦꯜ ꯂꯪꯁ ꯀꯦꯟꯁꯔ - ꯑꯦꯟ.ꯑꯦꯁ.ꯁꯤ.ꯑꯦꯜ.ꯁꯤ.)ꯗꯥ ꯃꯔꯨꯑꯣꯏꯅꯥ ꯊꯣꯀꯄꯥ ꯏ.ꯖꯤ.ꯑꯦꯐ.ꯑꯥꯔ. ꯃꯁꯤꯒꯤ ꯃꯇꯨꯡ ꯏꯟꯅꯥ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯆꯨꯅꯕꯥ `ꯇꯥꯔꯒꯦꯠ ꯊꯦꯔꯥꯄꯤ` ꯈꯅꯒꯠꯄꯥ ꯌꯥꯏ꯫
• ꯒꯥꯔꯗꯦꯟꯇ꯳꯶꯰® ꯁꯤ.ꯗꯤ.ꯑꯦꯛꯁ.: ꯃꯁꯤꯅꯥ ꯁꯤ.ꯇꯤ.ꯗꯤ.ꯑꯦꯟ.ꯑꯦ. ꯃꯁꯤꯅꯥ ꯀꯦꯟꯁꯔ ꯃꯈꯜ ꯀꯌꯥꯗꯥ ꯎꯕꯥ ꯐꯪꯂꯤꯕꯥ ꯀꯃꯟ ꯑꯣꯏꯕꯥ ꯖꯦꯅꯦꯇꯤꯛ ꯑꯣꯏꯕꯥ ꯑꯍꯣꯡꯕꯁꯤꯡ ꯈꯉꯗꯣꯀꯏ ꯑꯃꯁꯨꯡ ꯗꯣꯛꯇꯔꯁꯤꯡꯗꯥ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯏꯐꯦꯛꯇꯤꯕ ꯑꯣꯏꯕꯥ ꯂꯥꯌꯦꯡ ꯈꯅꯕꯗꯥ ꯃꯇꯦꯡ ꯄꯥꯡꯏ꯫
• ꯐꯥꯎꯟꯗꯦꯁꯟꯋꯥꯟ® ꯂꯤꯛꯕꯤꯗ ꯁꯤ.ꯗꯤ.ꯑꯦꯛꯁ.: ꯃꯁꯤ ꯇꯣꯉꯥꯟ-ꯇꯣꯉꯥꯅꯕꯥ ꯃꯈꯂꯒꯤ ꯀꯦꯟꯁꯔꯗꯥ ꯖꯦꯅꯦꯇꯤꯛ ꯑꯣꯏꯕꯥ ꯑꯍꯣꯡꯕꯁꯤꯡ ꯈꯉꯗꯣꯛꯅꯕꯥ ꯁꯤꯖꯤꯟꯅꯕꯥ ꯁꯤ.ꯇꯤ.ꯗꯤ.ꯑꯦꯟ.ꯑꯦ.

ꯃꯁꯤꯒꯤ ꯇꯦꯁ꯭ꯠ ꯑꯁꯤ ꯑꯋꯥꯕꯥ ꯑꯣꯏꯕꯔꯥ? ꯔꯤꯖꯜꯇ ꯐꯪꯕꯗꯥ ꯃꯇꯝ ꯀꯌꯥ ꯆꯪꯕꯒꯦ?

ꯂꯤꯛꯕꯤꯗ ꯕꯥꯏꯑꯣꯞꯁꯤꯒꯤ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯐꯕꯥ ꯋꯥꯐꯃꯗꯤ ꯃꯁꯤ ꯌꯥꯝꯅꯥ ꯏꯆꯝ ꯆꯝꯕꯥ, ꯑꯋꯥꯕꯥ ꯂꯩꯇꯕꯥ ꯊꯧꯑꯣꯡ ꯑꯃꯅꯤ꯫ ꯃꯁꯤ ꯆꯥꯡ ꯅꯥꯏꯅꯥ ꯏ ꯇꯦꯁ꯭ꯠ ꯇꯧꯅꯕꯥ ꯏ ꯄꯤꯕꯒꯥ ꯃꯥꯟꯅꯩ꯫ ꯅꯤꯗꯜ ꯑꯗꯨ ꯊꯥꯗꯣꯔꯀꯄꯥ ꯃꯇꯃꯗꯥ ꯈꯔꯥ ꯁꯣꯀꯄꯥ ꯅꯠꯇꯅꯥ ꯑꯇꯩ ꯑꯅꯥꯕꯥ ꯑꯃꯠꯇꯥ ꯂꯩꯇꯦ꯫

ꯅꯍꯥꯛꯀꯤ ꯏꯒꯤ ꯁꯦꯝꯄꯜ ꯑꯗꯨ ꯂꯦꯕ ꯑꯃꯗꯥ ꯊꯥꯏ, ꯃꯐꯃꯗꯨꯗꯥ ꯄꯦꯊꯣꯂꯣꯖꯤꯁ꯭ꯇꯁꯤꯡꯅꯥ ꯄ꯭ꯂꯥꯖꯃꯥ ꯑꯗꯨ ꯏꯗꯒꯤ ꯇꯣꯈꯥꯌꯅꯥ ꯊꯃꯗꯨꯅꯥ ꯁꯤ.ꯇꯤ.ꯁꯤ.ꯁꯤꯡ ꯅꯠꯠꯔꯒꯥ ꯁꯤ.ꯇꯤ.ꯗꯤ.ꯑꯦꯟ.ꯑꯦ. ꯃꯍꯧꯁꯥꯅꯥ ꯔꯤꯖꯜꯇ ꯐꯪꯕꯗꯥ ꯅꯨꯃꯤꯠ ꯑꯅꯤꯗꯒꯤ ꯑꯍꯨꯝ ꯐꯥꯎꯕꯥ ꯆꯪꯏ꯫

ꯔꯤꯖꯜꯇꯁꯤꯡ ꯑꯁꯤꯅꯥ ꯅꯍꯥꯛꯀꯤ ꯏꯒꯤ ꯁꯦꯝꯄꯜ ꯑꯗꯨꯗꯥ ꯀꯦꯟꯁꯔ ꯁꯦꯂꯁꯤꯡ ꯅꯠꯠꯔꯒꯥ ꯗꯤ.ꯑꯦꯟ.ꯑꯦ.ꯒꯤ ꯁꯔꯨꯀꯁꯤꯡ (ꯄꯣꯖꯤꯇꯤꯕ) ꯅꯠꯠꯔꯒꯥ ꯌꯥꯑꯣꯗꯕꯥ (ꯅꯦꯒꯦꯇꯤꯕ) ꯂꯩꯕ꯭ꯔꯥ ꯍꯥꯌꯕꯗꯨ ꯈꯪꯍꯜꯂꯤ꯫ ꯀꯔꯤꯒꯨꯝꯕꯥ ꯄꯣꯖꯤꯇꯤꯕ ꯑꯣꯏꯔꯕꯗꯤ ꯇꯦꯁ꯭ꯠ ꯈꯔꯅꯥ ꯃꯈꯣꯌ ꯑꯁꯤ ꯀꯔꯤ ꯃꯈꯂꯒꯤ ꯀꯦꯟꯁꯔꯗꯒꯤ ꯂꯥꯀꯄꯅꯣ ꯑꯃꯁꯨꯡ ꯃꯈꯣꯌꯗꯥ ꯀꯔꯤ ꯖꯤꯅꯦꯇꯤꯛ ꯑꯣꯏꯕꯥ ꯑꯍꯣꯡꯕꯥ ꯂꯩꯕꯒꯦ ꯍꯥꯌꯕꯗꯨꯁꯨ ꯈꯉꯕꯥ ꯉꯃꯒꯅꯤ꯫